© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor-in-Chief: Peter Gregory, Deputy Editors: Mary De Vita, Duoduo Liang, Lorna Stimson
Online ISSN: 1521-4095
Associated Title(s): Advanced Electronic Materials, Advanced Energy Materials, Advanced Engineering Materials, Advanced Functional Materials, Advanced Healthcare Materials, Advanced Materials Interfaces, Advanced Materials Technologies, Advanced Optical Materials, Advanced Science, Laser & Photonics Reviews, Particle & Particle Systems Characterization, Small
Inside Front Cover: Enzyme-Based Multi-Component Optical Nanoprobes for Sequence-Specific Detection of DNA Hybridization (Adv. Mater. 3/2008)
A novel multicomponent gold nanoparticle (AuNP)-based nanoprobe can be assembled from a thiolated DNA detection probe, horseradish peroxidase (HRP), and bovine serum albumin (BSA), report Shiping Song, Yun Zhao, Chunhui Fan, and co-workers on p. 497. The DNA detection probe is employed to construct a complex for “sandwich”-based DNA detection, the HRP translates the hybridization event into an enzymatic catalysis-based optical signal, and BSA serves as a non-specific blocker.