Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor-in-Chief: Peter Gregory, Deputy Editors: Martin Ottmar, Carolina Novo da Silva, Lorna Stimson
Online ISSN: 1521-4095
Associated Title(s): Advanced Energy Materials, Advanced Engineering Materials, Advanced Functional Materials, Advanced Healthcare Materials, Advanced Materials Interfaces, Advanced Optical Materials, Particle & Particle Systems Characterization, Small
Artificial Vasculature: Rapid Fabrication of Bio-inspired 3D Microfluidic Vascular Networks (Adv. Mater. 35/2009)
The cover depicts a 3D microchannel network embedded inside an acrylic polymer substrate. The network is created using an electrostatic discharge method that instantaneously vaporizes and fractures the substrate, leaving behind a tree-like fractal arrangement of microchannels bearing a remarkable similarity to naturally occurring vasculature. The ability to rapidly construct microchannel networks incorporating a wide range of diameters (∼10–500 µm) may help enable production of organ-sized engineered tissue scaffolds containing embedded vasculature, as reported by Arul Jayaraman, Victor Ugaz, and co-workers on p. 3567.