Advanced Materials

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21_36b/2009Mercury Biosensors: Polydiacetylene–Liposome Microarrays for Selective and Sensitive Mercury(II) Detection (Adv. Mater. 36/2009)

Polydiacetylene (PDA) liposome microarrays have been developed for selective and sensitive mercury detection. The sensors, reported on p. 3674 by Jinsang Kim and co-workers, are designed to produce red fluorescence emission upon binding with Hg2+; when the single-stranded DNA aptamers on the microarray selectively wrap around the mercury ions, the resulting complexes repulse each other. The epoxy-based PDA liposome design is an excellent universal platform that can be readily extended to other sensor designs.

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