Advanced Materials

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22_37b/2010Cellular Imaging: Conjugated Oligoelectrolyte Harnessed Polyhedral Oligomeric Silsesquioxane as Light-Up Hybrid Nanodot for Two-Photon Fluorescence Imaging of Cellular Nucleus (Adv. Mater. 37/2010)

Bin Liu and co-workers report on p. 4186 on a water-soluble organic/inorganic hybrid nanodot based on polyhedral oligomeric silsesquioxane (POSS) and conjugated oligoelectrolytes for twophoton fluorescence imaging of cellular nuclei. The small size of the dots (∼3.3 nm) impart nucleus permeability and substantial DNA-enhanced twophoton excited fluorescence that allows highcontrast illumination of the nucleus.

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