Advanced Materials

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23_36/2011Surface-Enhanced Raman Spectroscopy: Reversible Tuning of SERS Hot Spots with Aptamers (Adv. Mater. 36/2011)

On page 4152, Martin Moskovits and co-workers report a reversible surface-enhanced Raman spectroscopy (SERS)-based sensor consisting of gold nanoparticles tethered with stem loop aptamers capable of delivering robust signals from sensing events involving as few as two target molecules. Washing the sensor with buffer causes the SERS spectrum to revert to its pre-detection-event form, fully restoring its capability as a sensor.

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