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Editor-in-Chief: Peter Gregory, Deputy Editors: Mary De Vita, Duoduo Liang, Lorna Stimson
Online ISSN: 1521-4095
Associated Title(s): Advanced Electronic Materials, Advanced Energy Materials, Advanced Engineering Materials, Advanced Functional Materials, Advanced Healthcare Materials, Advanced Materials Interfaces, Advanced Materials Technologies, Advanced Optical Materials, Advanced Science, Laser & Photonics Reviews, Particle & Particle Systems Characterization, Small
Lipid Nanoparticles: Peptide Targeted Lipid Nanoparticles for Anticancer Drug Delivery (Adv. Mater. 28/2012)
Nanoparticles reach the tumor through the “leaky” tumor vasculature that allows the transfer of large molecules out of the blood stream. Once in the tumor microenvironment targeting peptides on the surface of the nanoparticles allow specific binding by tumor-cell receptors and subsequent cell internalization. On page 3803, E. Kokkoli and co-workers review the recent strategies used to create peptide-targeted lipid nano-particles to improve cancer therapy.