25_02i/2013Gene Delivery: Plasmid-Templated Shape Control of Condensed DNA–Block Copolymer Nanoparticles (Adv. Mater. 2/2013)

Micellar nanoparticles are created by Hai-Quan Mao, Erik Luijten, and co-workers on page 227 through complexation of plasmid DNA (green) and block copolymers (blue/brown). Variation of solvent polarity allows systematic control over the micelle shape (modeling images are shown in the foreground of the image and transmission electron microscopy images in the background) without changing their chemical composition, paving the way for targeted gene delivery.

| Table of Contents