Advanced Materials

Cover image for Vol. 28 Issue 46

25_21i/2013Tumor Cell Isolation: High-Purity Prostate Circulating Tumor Cell Isolation by a Polymer Nanofiber-Embedded Microchip for Whole Exome Sequencing (Adv. Mater. 21/2013)

A nanofiber-embedded NanoVelcro Chip is coupled with ArcturusXT laser capture microdissection technology to enable the detection and isolation of single circulating tumor cells from patients with prostate cancer. Edwin M. Posadas and co-workers demonstrate on page 2897 the capacity of conducting whole exome sequencing on single circulating tumor cells.

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