Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor-in-Chief: Peter Gregory, Deputy Editors: Mary Farrell, Duoduo Liang, Lorna Stimson
Online ISSN: 1521-4095
Associated Title(s): Advanced Electronic Materials, Advanced Energy Materials, Advanced Engineering Materials, Advanced Functional Materials, Advanced Healthcare Materials, Advanced Materials Interfaces, Advanced Optical Materials, Advanced Science, Particle & Particle Systems Characterization, Small
Scaffolds: 3D Structural Patterns in Scalable, Elastomeric Scaffolds Guide Engineered Tissue Architecture (Adv. Mater. 32/2013)
Microfabricated biodegradable scaffolds with 3D structural patterns are created by semi-automated layer-by-layer assembly of elastomeric polymer sheets with through-pores, as described by Lisa E. Freed and co-workers on page 4459. The 3D pore network architecture defined by the relative alignment of layers directed cell and muscle-like fiber orientation in skeletal and cardiac muscle. In this picture, heart cell bundles weave through a pore network created in a multi-layer poly(glycerol sebacate) (PGS) scaffold.