Theranostic Graphene Oxide for Prostate Cancer Detection and Treatment
Suhash Reddy Chavva, Avijit Pramanik, Bhanu Priya Viraka Nellore, Sudarson Sekhar Sinha, Brian Yust, Rajashekhar Kanchanapally, Zhen Fan, Rebecca A Crouch, Anant Kumar Singh, Bethany Neyland, Kimberly Robinson, Xuemei Dai, Dhiraj Sardar, Yuefeng Lu and Paresh Chandra Ray
Article first published online: 27 AUG 2014 | DOI: 10.1002/ppsc.201400143
Epithelial cell adhesion molecule (EpCAM) antibody and A9-aptamer-attached theranostic graphene oxide (GO) are successfully developed for the separation and capturing of circulating tumor cell (CTC) from infected blood. The report shows thattheranostic GO is capable of external near-IR 785 nm light-driven combined synergistic photothermal and photodynamic treatment of prostate cancer.