Journal of Bone and Mineral Research

Cover image for Vol. 30 Issue 2

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: Juliet E Compston

Impact Factor: 6.589

ISI Journal Citation Reports © Ranking: 2013: 12/124 (Endocrinology & Metabolism)

Online ISSN: 1523-4681


  1. 1 - 92
  1. Original Articles

    1. Osteoblast-Specific γ-Glutamyl Carboxylase-Deficient Mice Display Enhanced Bone Formation with Aberrant Mineralization

      Kotaro Azuma, Sachiko Shiba, Tomoka Hasegawa, Kazuhiro Ikeda, Tomohiko Urano, Kuniko Horie-Inoue, Yasuyoshi Ouchi, Norio Amizuka and Satoshi Inoue

      Accepted manuscript online: 20 JAN 2015 06:26AM EST | DOI: 10.1002/jbmr.2463

    2. Glycated Hemoglobin Level and Risk of Hip Fracture in Older People with Type 2 Diabetes: A Competing Risk Analysis of Taiwan Diabetes Cohort Study

      Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin, Ching-Chu Chen, Sing-Yu Yang, Hsuan-Ju Chen, Cheng-Chieh Lin and Tsai-Chung Li

      Accepted manuscript online: 17 JAN 2015 01:42PM EST | DOI: 10.1002/jbmr.2462

    3. Single-Limb Irradiation Induces Local and Systemic Bone Loss in a Murine Model

      Laura E. Wright, Jeroen T. Buijs, Hun-Soo Kim, Laura E. Coats, Anne M. Scheidler, Sutha K. John, Yun She, Sreemala Murthy, Ning Ma, Helen J. Chin- Sinex, Teresita M. Bellido, Ted A. Bateman, Marc S. Mendonca, Khalid S. Mohammad and Theresa A. Guise

      Accepted manuscript online: 15 JAN 2015 05:38AM EST | DOI: 10.1002/jbmr.2458

    4. The Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5

      Timur A. Yorgan, Stephanie Peters, Anke Jeschke, Peggy Benisch, Franz Jakob, Michael Amling and Thorsten Schinke

      Accepted manuscript online: 15 JAN 2015 05:37AM EST | DOI: 10.1002/jbmr.2461

  2. Commentaries

    1. You have free access to this content
      Unlocking the Sost Gene

      Mark L. Johnson

      Accepted manuscript online: 15 JAN 2015 05:37AM EST | DOI: 10.1002/jbmr.2459

  3. Letters to the Editor

    1. Rapid Skeletal Turnover in Radiographic Mimic of Osteopetrosis Might Be Secondary to Systemic Mastocytosis

      Maurizio Rossini, Ombretta Viapiana, Silvano Adami, Luca Idolazzi, Roberta Zanotti and Davide Gatti

      Accepted manuscript online: 15 JAN 2015 05:36AM EST | DOI: 10.1002/jbmr.2456

  4. Original Articles

    1. Mapping Bone Changes at the Proximal Femoral Cortex of Postmenopausal Women in Response to Alendronate and Teriparatide Alone, Combined or Sequentially

      Tristan Whitmarsh, Graham M. Treece, Andrew H. Gee and Kenneth E. S. Poole

      Accepted manuscript online: 15 JAN 2015 05:19AM EST | DOI: 10.1002/jbmr.2454

    2. Spatiotemporal Analyses of Osteogenesis and Angiogenesis via Intravital Imaging in Cranial Bone Defect Repair

      Chunlan Huang, Vincent P. Ness, Xiaochuan Yang, Hongli Chen, Jiebo Luo, Edward B Brown and Xinping Zhang

      Accepted manuscript online: 15 JAN 2015 05:18AM EST | DOI: 10.1002/jbmr.2460

  5. Letters to the Editor

    1. Reply to “Rapid Skeletal Turnover in Radiographic Mimic of Osteopetrosis Might Be Secondary to Systemic Mastocytosis”

      Michael P. Whyte, Katherine L. Madson, William H. McAlister, Steven Mumm, Deborah V. Novack, Jo C. Blair and Nicholas J. Shaw

      Accepted manuscript online: 15 JAN 2015 05:13AM EST | DOI: 10.1002/jbmr.2455

    2. Comment on “Major Source of Error When Calculating Bone Mechanical Properties”

      Gary S. Beaupre

      Accepted manuscript online: 15 JAN 2015 05:12AM EST | DOI: 10.1002/jbmr.2457

  6. Original Articles

    1. Adverse effects of osteocytic constitutive activation of ß-catenin on bone strength and bone growth

      Sixu Chen, Jianquan Feng, Quanwei Bao, Ang Li, Bo Zhang, Yue Shen, Yufeng Zhao, Qingshan Guo, Junjun Jing, Shuxian Lin and Zhaowen Zong

      Accepted manuscript online: 12 JAN 2015 06:18AM EST | DOI: 10.1002/jbmr.2453

    2. Identifying novel clinical surrogates to assess human bone fracture toughness

      Mathilde Granke, Alexander J Makowski, Sasidhar Uppuganti, Mark D Does and Jeffry S Nyman

      Accepted manuscript online: 12 JAN 2015 06:18AM EST | DOI: 10.1002/jbmr.2452

    3. Disruption of Scube2 impairs endochondral bone formation

      Yuh-Charn Lin, Steve R. Roffler, Yu-Ting Yan and Ruey-Bing Yang

      Accepted manuscript online: 12 JAN 2015 06:18AM EST | DOI: 10.1002/jbmr.2451

    4. Low Magnitude Mechanical Stimulation to Improve Bone Density in Persons of Advanced Age: A Randomized, Placebo-Controlled Trial

      Douglas P. Kiel, Marian T. Hannan, Bruce A. Barton, Mary L. Bouxsein, Emily Sisson, Thomas Lang, Brett Allaire, Dawn Dewkett, Danette Carroll, Jay Magaziner, Elizabeth Shane, Elizabeth Teng Leary, Sheryl Zimmerman and Clinton Rubin

      Accepted manuscript online: 8 JAN 2015 05:53AM EST | DOI: 10.1002/jbmr.2448

    5. Neural Crest-Specific TSC1 Deletion in Mice Leads to Sclerotic Craniofacial Bone Lesion

      Fang Fang, Shaogang Sun, Li Wang, Jun-Lin Guan, Marco Giovannini, Yuan Zhu and Fei Liu

      Accepted manuscript online: 6 JAN 2015 05:25AM EST | DOI: 10.1002/jbmr.2447

    6. The Association Between BMI and QCT-Derived Proximal Hip Structure and Strength in Older Men: A Cross-Sectional Study

      Jian Shen, Carrie M Nielson, Lynn M Marshall, David C Lee, Tony M Keaveny, Eric S Orwoll and for the Osteoporotic Fractures in Men (MrOS) Research Group

      Accepted manuscript online: 6 JAN 2015 05:23AM EST | DOI: 10.1002/jbmr.2450

  7. Short Reports

    1. Legg-Calvé-Perthes Disease Produces Chronic Hip Synovitis and Elevation of Interleukin-6 in the Synovial Fluid

      Nobuhiro Kamiya, Ryosuke Yamaguchi, Naga Suresh Adapala, Elena Chen, David Neal, Jack O'Brien, Alec Thoveson, Paul Gudmundsson, Case Brabham, Olumide Aruwajoye, Hicham Drissi and Harry K.W. Kim

      Accepted manuscript online: 1 JAN 2015 10:16PM EST | DOI: 10.1002/jbmr.2435

  8. Original Articles

    1. Wnt Acts as a Pro-Survival Signal to Enhance Dentin Regeneration

      D.J. Hunter, C. Bardet, S. Mouraret, B. Liu, G. Singh, J. Sadoine, G. Dhamdhere, A. Smith, X.V. Tran, A. Joy, S. Rooker, S. Suzuki, A. Vuorinen, S. Miettinen, C. Chaussain and J.A. Helms

      Accepted manuscript online: 1 JAN 2015 10:15PM EST | DOI: 10.1002/jbmr.2444

    2. Activation of the Canonical Wnt Signaling Pathway Induces Cementum Regeneration

      Pingping Han, Saso Ivanovski, Ross Crawford and Yin Xiao

      Accepted manuscript online: 1 JAN 2015 10:15PM EST | DOI: 10.1002/jbmr.2445

    3. RECQL4 Regulates p53 Function in vivo During Skeletogenesis

      Linchao Lu, Karine Harutyunyan, Weidong Jin, Jianhong Wu, Tao Yang, Yuqing Chen, Kyu Sang Joeng, Yangjin Bae, Jianning Tao, Brian C. Dawson, Ming-Ming Jiang, Brendan Lee and Lisa L. Wang

      Accepted manuscript online: 1 JAN 2015 10:14PM EST | DOI: 10.1002/jbmr.2436

  9. Clinical Trials

    1. The Effect of 6 versus 9 Years of Zoledronic Acid Treatment in Osteoporosis: A Randomized Second Extension to the HORIZON-Pivotal Fracture Trial (PFT)

      Dennis M Black, Ian R Reid, Jane A Cauley, Felicia Cosman, Ping Chung Leung, Peter Lakatos, Kurt Lippuner, Steven R Cummings, Trisha F Hue, Amitava Mukhopadhyay, Monique Tan, R Paul Aftring and Richard Eastell

      Accepted manuscript online: 26 DEC 2014 01:20AM EST | DOI: 10.1002/jbmr.2442

  10. Original Articles

    1. Association of QCT bone mineral density and bone structure with vertebral fractures in patients with multiple myeloma

      J. Borggrefe, S. Giravent, F. Thomsen, J. Peña, G. Campbell, A. Wulff, A. Günther, M. Heller and C.C. Glüer

      Accepted manuscript online: 26 DEC 2014 01:19AM EST | DOI: 10.1002/jbmr.2443

    2. Role of the parathyroid hormone type 1 receptor (PTH1R) as a mechanosensor in osteocyte survival

      Marta Maycas, Juan A. Ardura, Luis Fernández de Castro, Beatriz Bravo, Arancha R. Gortázar and Pedro Esbrit

      Accepted manuscript online: 22 DEC 2014 04:55AM EST | DOI: 10.1002/jbmr.2439

    3. Bone Volume Fraction and Fabric Anisotropy Are Better Determinants of Trabecular Bone Stiffness than Other Morphological Variables

      Dr. Ghislain Maquer, MSc Sarah N. Musy, Dr. Jasmin Wandel, Dr. Thomas Gross and Prof. Philippe K. Zysset

      Accepted manuscript online: 22 DEC 2014 03:20AM EST | DOI: 10.1002/jbmr.2437

    4. PTH Signaling During Exercise Contributes to Bone Adaptation

      Joseph D. Gardinier, Fatma Mohamed and David H. Kohn

      Accepted manuscript online: 22 DEC 2014 03:19AM EST | DOI: 10.1002/jbmr.2432

    5. MicroRNA-140 provides robustness to the regulation of hypertrophic chondrocyte differentiation by the PTHrP-HDAC4 pathway

      Garyfallia Papaioannou, Fatemeh Mirzamohammadi, Thomas S. Lisse, Shigeki Nishimori, Marc N. Wein and Tatsuya Kobayashi

      Accepted manuscript online: 22 DEC 2014 03:18AM EST | DOI: 10.1002/jbmr.2438

    6. Mendelian randomisation analysis to examine for a causal effect of urate on bone mineral density

      Nicola Dalbeth, Ruth Topless, Tanya Flynn, Murray Cadzow, Mark J Bolland and Tony R Merriman

      Accepted manuscript online: 15 DEC 2014 01:16AM EST | DOI: 10.1002/jbmr.2434

    7. Gender specific differences in the skeletal response to continuous PTH in mice lacking the IGF1 receptor in mature osteoblasts

      Muriel Babey, Yongmei Wang, Takuo Kubota, Chak Fong, Alicia Menendez, Hashem Z. ElAlieh and Daniel D. Bikle

      Accepted manuscript online: 12 DEC 2014 03:32AM EST | DOI: 10.1002/jbmr.2433

    8. Relationship Between Serum Uric Acid and Bone Mineral Density in the General Population and in Rats with Experimental Hyperuricemia

      Dihua Zhang, I. Alexandru Bobulescu, Naim M. Maalouf, Beverley Adams-Huet, John Poindexter, Sun Park, Fuxin Wei, Christopher Chen, Orson W. Moe and Khashayar Sakhaee

      Accepted manuscript online: 10 DEC 2014 06:25AM EST | DOI: 10.1002/jbmr.2430

  11. Case Reports

    1. The calcineurin inhibitor tacrolimus as a new therapy in severe cherubism

      Natacha Kadlub, Marie-Paule Vazquez, Louise Galmiche, Aurore Coulomb L'Herminé, Linda Dainese, Tim Ulinski, Brigitte Fauroux, Ioana Pavlov, Cécile Badoual, Sandrine Marlin, Marcel Deckert, Nicolas Leboulanger, Ariane Berdal, Vianney Descroix, Arnaud Picard and Amélie E. Coudert

      Accepted manuscript online: 10 DEC 2014 06:25AM EST | DOI: 10.1002/jbmr.2431

  12. Original Articles

    1. Inner ear vestibular signals regulate bone remodeling via the sympathetic nervous system

      G Vignaux, JDLC Ndong, D Perrien and F Elefteriou

      Accepted manuscript online: 10 DEC 2014 06:25AM EST | DOI: 10.1002/jbmr.2426

    2. Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis

      Linda Vi, Gurpreet S. Baht, Heather Whetstone, Adeline Ng, Qingxia Wei, Raymond Poon, Sivakami Mylvaganam, Marc Grynpas and Benjamin A. Alman

      Accepted manuscript online: 8 DEC 2014 03:15AM EST | DOI: 10.1002/jbmr.2422

    3. Osteoblast-specific expression of the Fibrous Dysplasia (FD) causing mutation, GsαR201C produces a high bone mass phenotype but does not reproduce FD in the mouse

      Cristina Remoli, Stefano Michienzi, Benedetto Sacchetti, Alberto Di Consiglio, Stefania Cersosimo, Emanuela Spica, Pamela G. Robey, Kenn Holmbeck, Ana Cumano, Alan Boyde, Graham Davis, Isabella Saggio, Mara Riminucci and Paolo Bianco

      Accepted manuscript online: 8 DEC 2014 03:14AM EST | DOI: 10.1002/jbmr.2425

    4. Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation

      Aránzazu Mediero, Bhama Ramkhelawon, Miguel Perez-Aso, Kathryn J. Moore and Bruce N. Cronstein

      Accepted manuscript online: 8 DEC 2014 03:10AM EST | DOI: 10.1002/jbmr.2421

    5. PTH(1-34) Treatment Increases Bisphosphonate Turnover in Fracture Repair in Rats

      Ciara M Murphy, Aaron Schindeler, Laurence C Cantrill, Kathy Mikulec, Lauren Peacock and David G Little

      Accepted manuscript online: 8 DEC 2014 03:09AM EST | DOI: 10.1002/jbmr.2424

    6. Effect of recent spinal cord injury on Wnt signaling antagonists (sclerostin and Dkk-1) and their relationship with bone loss. A 12-month prospective study

      L Gifre, J Vidal, JL Carrasco, X Filella, S Ruiz-Gaspà, A Muxi, E Portell, A Monegal, N Guañabens and P Peris

      Accepted manuscript online: 8 DEC 2014 03:09AM EST | DOI: 10.1002/jbmr.2423

    7. Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification

      Campbell R. Sheen, Pia Kuss, Sonoko Narisawa, Manisha C. Yadav, Jessica Nigro, Wei Wang, T. Nicole Chhea, Eduard A. Sergienko, Kapil Kapoor, Michael R. Jackson, Marc. F. Hoylaerts, Anthony B. Pinkerton, W. Charles O'Neill and José Luis Millán

      Accepted manuscript online: 27 NOV 2014 02:06AM EST | DOI: 10.1002/jbmr.2420

    8. The excess risk of major osteoporotic fractures in hypothyroidism is driven by cumulative hyperthyroid as opposed to hypothyroid time. An observational register-based time resolved cohort analysis

      Bo Abrahamsen, Henrik L Jørgensen, Anne Sofie Laulund, Mads Nybo, Doug C Bauer, Thomas H Brix and Laszlo Hegedüs

      Accepted manuscript online: 27 NOV 2014 02:06AM EST | DOI: 10.1002/jbmr.2416

    9. A DNA Segment Spanning the Mouse Tnfsf11 Transcription Unit and Its Upstream Regulatory Domain Rescues the Pleiotropic Biologic Phenotype of the RANKL Null Mouse

      M. Onal, K.A. Bishop, H.C. St. John, A.L. Danielson, E. M. Riley, M. Piemontese, J. Xiong, J.J. Goellner, C.A. O'Brien and J.W. Pike

      Accepted manuscript online: 27 NOV 2014 02:06AM EST | DOI: 10.1002/jbmr.2417

    10. Genome-wide comprehensive analysis reveals critical cooperation between Smad and c-Fos in RANKL-induced osteoclastogenesis

      Yasunori Omata, Tetsuro Yasui, Jun Hirose, Naohiro Izawa, Yuuki Imai, Takumi Matsumoto, Hironari Masuda, Naoto Tokuyama, Shinya Nakamura, Shuichi Tsutsumi, Hisataka Yasuda, Kazuo Okamoto, Hiroshi Takayanagi, Atsuhiko Hikita, Takeshi Imamura, Koichi Matsuo, Taku Saito, Yuho Kadono, Hiroyuki Aburatani and Sakae Tanaka

      Accepted manuscript online: 27 NOV 2014 02:02AM EST | DOI: 10.1002/jbmr.2418

    11. Femoral Volumetric Bone Density, Geometry, and Strength in Relation to 25-Hydroxy Vitamin D in Older Men

      Elizabeth Martin, Elizabeth Haney, Jackie Shannon, Jane Cauley, Kristine Ensrud, Tony Keaveny, Joseph Zmuda, Eric Orwoll, Stephanie Litwack Harrison and Lynn Marshall

      Accepted manuscript online: 24 NOV 2014 04:37AM EST | DOI: 10.1002/jbmr.2360

    12. An investigation of the mineral in ductile and brittle cortical mouse bone

      Naiara Rodriguez-Florez, Esther Garcia-Tunon, Quresh Mukadam, Eduardo Saiz, Karla J. Oldknow, Colin Farquharson, José Luis Millán, Alan Boyde and Sandra J. Shefelbine

      Accepted manuscript online: 22 NOV 2014 03:06AM EST | DOI: 10.1002/jbmr.2414

    13. Myelosuppressive therapies significantly increase pro-inflammatory cytokines and directly cause bone loss

      Julie M. Quach, Maria Askmyr, Tanja Jovic, Emma K. Baker, Nicole C. Walsh, Simon J. Harrison, Paul Neeson, David Ritchie, Peter R. Ebeling and Louise E. Purton

      Accepted manuscript online: 22 NOV 2014 03:05AM EST | DOI: 10.1002/jbmr.2415

    14. The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development

      Diana Rigueur, Sean Brugger, Teni Anbarchian, Jong Kil Kim, Yoo Jin Lee and Karen Lyons

      Accepted manuscript online: 21 NOV 2014 04:55AM EST | DOI: 10.1002/jbmr.2385

    15. MiR-497~195 cluster microRNAs regulate osteoblast differentiation by targeting BMP signaling

      Grünhagen J, Bhushan R, Degenkolbe E, Jäger M, Knaus P, Mundlos S, Robinson PN and Ott CE

      Accepted manuscript online: 19 NOV 2014 01:29AM EST | DOI: 10.1002/jbmr.2412

    16. Androgen receptor action in osteoblasts in male mice is dependent on their stage of maturation

      Patricia K Russell, Michele V Clarke, Karey Cheong, Paul H Anderson, Howard A Morris, Kristine M Wiren, Jeffrey D Zajac and Rachel A Davey

      Accepted manuscript online: 19 NOV 2014 01:26AM EST | DOI: 10.1002/jbmr.2413

    17. Genetic and Environmental Variances of Bone Microarchitecture and Bone Remodeling Markers: A Twin Study

      Åshild Bjørnerem, Minh Bui, Xiaofang Wang, Ali Ghasem-Zadeh, John L Hopper, Roger Zebaze and Ego Seeman

      Accepted manuscript online: 18 NOV 2014 04:50PM EST | DOI: 10.1002/jbmr.2365

  13. Short Reports

    1. Role of Decorin in Multiple Myeloma (MM) Bone Marrow Microenvironment

      Neeharika Nemani, Loredana Santo, Homare Eda, Diana Cirstea, Yuko Mishima, Chirayu Patel, Elizabeth O'Donnell, Andrew Yee and Noopur Raje

      Accepted manuscript online: 18 NOV 2014 04:49PM EST | DOI: 10.1002/jbmr.2371

  14. Original Articles

    1. Bisphosphonates for the Prevention of Fractures in Osteogenesis Imperfecta: Meta-Analysis of Placebo-Controlled Trials

      Jannie D Hald, Evangelos Evangelou, Bente L Langdahl and Stuart H Ralston

      Accepted manuscript online: 18 NOV 2014 04:48PM EST | DOI: 10.1002/jbmr.2410

    2. The Enamel Protein Amelotin is a Promoter of Hydroxyapatite Mineralization

      Nastaran Abbarin, Symone San Miguel, James Holcroft, Kengo Iwasaki and Bernhard Ganss

      Accepted manuscript online: 18 NOV 2014 04:48PM EST | DOI: 10.1002/jbmr.2411

    3. Anti-Sclerostin Antibody Treatment in a Rat Model of Progressive Renal Osteodystrophy

      Sharon M. Moe, Neal X. Chen, Christopher L. Newman, Jason M. Organ, Michaela Kneissel, Ina Kramer, Vincent H. Gattone II and Matthew R. Allen

      Accepted manuscript online: 18 NOV 2014 04:46PM EST | DOI: 10.1002/jbmr.2372

    4. ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation

      Zhijun Chen, Susan X. Yue, Guang Zhou, Edward M. Greenfield and Shunichi Murakami

      Accepted manuscript online: 17 NOV 2014 05:42AM EST | DOI: 10.1002/jbmr.2409

    5. TSH elevations as the first laboratory evidence for pseudohypoparathyroidism type Ib (PHP-Ib)

      Angelo Molinaro, Dov Tiosano, Rieko Takatani, Dionisios Chrysis, William Russell, Nikolas Koscielniak, Marie-Laure Kottler, Patrizia Agretti, Giuseppina De Marco, Petteri Ahtiainen, Marta Christov, Outi Mäkitie, Massimo Tonacchera and Harald Jüppner

      Accepted manuscript online: 17 NOV 2014 04:06AM EST | DOI: 10.1002/jbmr.2408

    6. Bone mineral density predicts fractures in chronic kidney disease

      Sarah L West, Charmaine E Lok, Lisa Langsetmo, Angela M Cheung, Eva Szabo, Dawn Pearce, Maria Fusaro, Ron Wald, Jordan Weinstein and Sophie A Jamal

      Accepted manuscript online: 15 NOV 2014 04:27AM EST | DOI: 10.1002/jbmr.2406

    7. Bone Density, Microstructure and Strength in Obese and Normal Weight Men and Women in Younger and Older Adulthood

      Amy L Evans, Margaret A Paggiosi, Richard Eastell and Jennifer S Walsh

      Accepted manuscript online: 15 NOV 2014 04:27AM EST | DOI: 10.1002/jbmr.2407

    8. Atypical Femoral Fracture in Osteoporosis Pseudoglioma Syndrome Associated With Two Novel Compound Heterozygous Mutations in LRP5

      Nerea Alonso, Dinesh C. Soares, Eugene McCloskey, Gregory D. Summers, Stuart H. Ralston and Celia L. Gregson

      Accepted manuscript online: 10 NOV 2014 04:21PM EST | DOI: 10.1002/jbmr.2403

  15. Letters to the Editor

    1. Reply to The Effect of Vigorous Physical Activity and Body Composition on Cortical Bone Mass in Adolescence

      ALSPAC research group

      Accepted manuscript online: 7 NOV 2014 06:33PM EST | DOI: 10.1002/jbmr.2399

  16. Letter to the Editors

    1. The effect of vigorous physical activity and body composition on cortical bone mass in adolescence

      A Sayers, K Deere and JH Tobias

      Accepted manuscript online: 7 NOV 2014 04:43AM EST | DOI: 10.1002/jbmr.2400

  17. Original Articles

    1. Effects of Denosumab, Alendronate, or Denosumab Following Alendronate on Bone Turnover, Calcium Homeostasis, Bone Mass and Bone Strength in Ovariectomized Cynomolgus Monkeys

      Paul J. Kostenuik, Susan Y. Smith, Rana Samadfam, Jacquelin Jolette, Lei Zhou and Michael S. Ominsky

      Accepted manuscript online: 4 NOV 2014 05:54PM EST | DOI: 10.1002/jbmr.2401

    2. Lenz-Majewski Hyperostotic Dwarfism With Hyperphosphoserinuria From A Novel Mutation In PTDSS1 Encoding Phosphatidylserine Synthase 1

      Michael P. Whyte, Amanda Blythe, William H. McAlister, Angela R. Nenninger, Vinieth N. Bijanki and Steven Mumm

      Accepted manuscript online: 1 NOV 2014 01:11AM EST | DOI: 10.1002/jbmr.2398

    3. Sclerostin Inhibition Prevents Spinal Cord Injury Induced Cancellous Bone Loss

      Luke A. Beggs, Fan Ye, Payal Ghosh, Darren T. Beck, Christine F. Conover, Alexander Balaez, Julie R. Miller, Ean G. Phillips, Nigel Zheng, Alyssa A. Williams, J. Ignacio Aguirre, Thomas J. Wronski, Prodip K. Bose, Stephen E. Borst and Joshua F. Yarrow

      Accepted manuscript online: 31 OCT 2014 06:05AM EST | DOI: 10.1002/jbmr.2396

    4. T Cell Expressed CD40L Potentiates the Bone Anabolic Activity of Intermittent PTH Treatment

      Jerid W. Robinson, Jau-Yi Li, Lindsey D. Walker, Abdul Malik Tiyagi, Michael Reott, Mingcan Yu, Jonathan Adams, M. Neale Weitzmann and Roberto Pacifici

      Accepted manuscript online: 31 OCT 2014 06:01AM EST | DOI: 10.1002/jbmr.2394

  18. Letters to the Editor

    1. The Significance of Bone Mineral Density in the Depiction of Memento Mori

      Derek T O'Keeffe, Spyridoula Maraka and Robert Wermers

      Accepted manuscript online: 31 OCT 2014 05:59AM EST | DOI: 10.1002/jbmr.2395

  19. Original Articles

    1. Core Binding Factor β of Osteoblasts Maintains Cortical Bone Mass Via Stabilization of Runx2 in Mice

      Kyung-Eun Lim, Na-Rae Park, Xiangguo Che, Min-Su Han, Jae-Hwan Jeong, Shin-Yoon Kim, Clara Yongjoo Park, Haruhiko Akiyama, Jung-Eun Kim, Hyun-Mo Ryoo, Janet L. Stein, Jane B. Lian, Gary S. Stein and Je-Yong Choi

      Accepted manuscript online: 31 OCT 2014 05:47AM EST | DOI: 10.1002/jbmr.2397

  20. Short Reports

    1. Validation of Power Doppler Versus Contrast Enhanced Magnetic Resonance Imaging Quantification of Joint Inflammation in Murine Inflammatory Arthritis

      Echoe M. Bouta, Peony D. Banik, Ronald W. Wood, Homaira Rahimi, Christopher T. Ritchlin, Ralf G. Thiele and Edward M. Schwarz

      Accepted manuscript online: 31 OCT 2014 05:44AM EST | DOI: 10.1002/jbmr.2392

  21. Original Articles

    1. Risk of Subsequent Fractures and Mortality in Elderly Women and Men With Fragility Fractures With and Without Osteoporotic Bone Density: The Dubbo Osteoporosis Epidemiology Study

      Dana Bliuc, Dunia Alarkawi, Tuan V Nguyen, John A Eisman and Jacqueline R Center

      Accepted manuscript online: 31 OCT 2014 05:43AM EST | DOI: 10.1002/jbmr.2393

  22. Short Reports

    1. Essential role of Osterix for tooth root but not crown dentin formation

      Hua Zhang, Yong Jiang, Chunlin Qin, Ying Liu, Sunita P. Ho and Jian Q. Feng

      Accepted manuscript online: 27 OCT 2014 05:19PM EST | DOI: 10.1002/jbmr.2391

  23. Clinical Trials

  24. Original Articles

    1. Deletion of connexin43 in osteoblasts/osteocytes leads to impaired muscle formation in mice

      Hua Shen, Susan Grimston, Roberto Civitelli and Stavros Thomopoulos

      Accepted manuscript online: 27 OCT 2014 01:31PM EST | DOI: 10.1002/jbmr.2389

    2. Trabecular and Cortical Microstructure and Fragility of the Distal Radius in Women

      Y. Bala, Q. M. Bui, X. Wang, S. Iuliano, Q. Wang, A. Ghasem-Zadeh, T.D. Rozental, M.L. Bouxsein, R. Zebaze and E. Seeman

      Accepted manuscript online: 18 OCT 2014 05:12AM EST | DOI: 10.1002/jbmr.2388

    3. Fruit and vegetable intake and risk of hip fracture: A cohort study of Swedish men and women

      Liisa Byberg, Andrea Bellavia, Nicola Orsini, Alicja Wolk and Karl Michaëlsson

      Accepted manuscript online: 7 OCT 2014 01:21PM EST | DOI: 10.1002/jbmr.2384

    4. Hyponatremia and Fractures: Findings from the Osteoporotic Fractures in Men Study

      Sophie A Jamal, Spyridon Arampatzis, Stephanie Litwack Harrison, Roxana C Bucur, Kristine Ensrud, Eric S Orwoll and Douglas C Bauer

      Accepted manuscript online: 7 OCT 2014 01:16PM EST | DOI: 10.1002/jbmr.2383

    5. Novel EP4 Receptor Agonist-Bisphosphonate Conjugate Drug (C1) Promotes Bone Formation and Improves Vertebral Mechanical Properties in the Ovariectomized Rat Model of Postmenopausal Bone Loss

      Careesa C. Liu, Sally Hu, Gang Chen, John Georgiou, Steve Arns, Nag S. Kumar, Robert N. Young and Marc D. Grynpas

      Accepted manuscript online: 4 OCT 2014 04:33AM EST | DOI: 10.1002/jbmr.2382

    6. The 21st century landscape of adult fractures - Cohort study of a complete adult regional population

      Björn E Rosengren, Professor Magnus Karlsson, Professor Ingemar Petersson and Associate Professor Martin Englund

      Accepted manuscript online: 3 OCT 2014 03:50AM EST | DOI: 10.1002/jbmr.2370

    7. Connexin 43 Channels are Essential for Normal Bone Structure and Osteocyte Viability

      Huiyun Xu, Sumin Gu, Manuel A. Riquelme, Sirisha Burra, Danielle Callaway, Hongyun Cheng, Teja Guda, James Schmitz, Roberto J. Fajardo, Sherry L. Werner, Hong Zhao, Peng Shang, Mark L. Johnson, Lynda F. Bonewald and Jean X. Jiang

      Accepted manuscript online: 1 OCT 2014 02:08AM EST | DOI: 10.1002/jbmr.2374

    8. Coeliac Disease Autoimmunity and Hip Fracture Risk: Findings from a Prospective Cohort Study

      Katriina Heikkilä, Markku Heliövaara, Olli Impivaara, Heikki Kröger, Paul Knekt, Harri Rissanen, Markku Mäki and Katri Kaukinen

      Accepted manuscript online: 1 OCT 2014 02:06AM EST | DOI: 10.1002/jbmr.2380

    9. HDAC5 controls MEF2C-driven sclerostin expression in osteocytes

      Marc N. Wein, Jordan Spatz, Shigeki Nishimori, John Doench, David Root, Philip Babij, Kenichi Nagano, Roland Baron, Daniel Brooks, Mary Bouxsein, Paola Divieti Pajevic and Henry M. Kronenberg

      Accepted manuscript online: 1 OCT 2014 02:02AM EST | DOI: 10.1002/jbmr.2381

    10. A single nucleotide polymorphism in osteonectin 3' untranslated region regulates bone volume and is targeted by miR-433

      Neha S. Dole, Kristina Kapinas, Catherine B. Kessler, Siu-Pok Yee, Douglas J. Adams, Renata C. Pereira and Anne M. Delany

      Accepted manuscript online: 29 SEP 2014 03:57AM EST | DOI: 10.1002/jbmr.2378

    11. Cbfb regulates bone development by stabilizing Runx family proteins

      Xin Qin, Qing Jiang, Yuki Matsuo, Tetsuya Kawane, Hisato Komori, Takeshi Moriishi, Ichiro Taniuchi, Kosei Ito, Yosuke Kawai, Satoshi Rokutanda, Shinichi Izumi and Toshihisa Komori

      Accepted manuscript online: 29 SEP 2014 03:57AM EST | DOI: 10.1002/jbmr.2379

    12. Muscle Torque Relative to Cross-Sectional Area and the Functional Muscle-Bone Unit in Children and Adolescents with Chronic Disease

      Dale Y. Lee, Rachel J. Wetzsteon, Babette S. Zemel, Justine Shults, Jason M. Organ, Bethany J. Foster, Rita M. Herskovitz, Debbie L. Foerster and Mary B. Leonard

      Accepted manuscript online: 28 SEP 2014 10:06PM EST | DOI: 10.1002/jbmr.2375

    13. IL-4/CCL22/CCR4 Axis Controls Regulatory T Cell Migration That Suppress Inflammatory Bone Loss in Murine Experimental Periodontitis

      Ana Claudia Araujo-Pires, Andreia Espindola Vieira, Carolina Favaro Francisconi, Claudia Cristina Biguetti, Andrew Glowacki, Sayuri Yoshizawa, Ana Paula Campanelli, Ana Paula Favaro Trombone, Charles S Sfeir, Steven R Little and Gustavo P Garlet

      Accepted manuscript online: 28 SEP 2014 10:06PM EST | DOI: 10.1002/jbmr.2376

    14. You have full text access to this OnlineOpen article
      Planar Cell Polarity Aligns Osteoblast Division in Response to Substrate Strain

      GL Galea, LB Meakin, D Savery, H Taipaleenmaki, P Delisser, GS Stein, AJ Copp, AJ van Wijnen, LE Lanyon and JS Price

      Accepted manuscript online: 28 SEP 2014 09:59PM EST | DOI: 10.1002/jbmr.2377

    15. An insulin-sensitizing thiazolidinedione, which minimally activates PPARγ, does not cause bone loss

      Tomohiro Fukunaga, Wei Zou, Nidhi Rohatgi, Jerry R. Colca and Steven L. Teitelbaum

      Accepted manuscript online: 25 SEP 2014 11:23PM EST | DOI: 10.1002/jbmr.2364

    16. A transgenic mouse model of OI type V supports a neomorphic mechanism of the IFITM5 mutation

      Caressa D. Lietman, Ronit Marom, Elda Munivez, Terry K. Bertin, Ming-Ming Jiang, Yuqing Chen, Brian Dawson, MaryAnn Weis, David Eyre and Brendan Lee

      Accepted manuscript online: 23 SEP 2014 05:05AM EST | DOI: 10.1002/jbmr.2363

    17. WNT5A has Anti-Prostate Cancer Effects In Vitro and Reduces Tumor Growth in the Skeleton In Vivo

      Stefanie Thiele, Andy Göbel, Tilman D. Rachner, Susanne Fuessel, Michael Froehner, Michael H. Muders, Gustavo B. Baretton, Ricardo Bernhardt, Franz Jakob, Claus C. Glüer, Martin Bornhäuser, Martina Rauner and Lorenz C. Hofbauer

      Accepted manuscript online: 15 SEP 2014 01:53PM EST | DOI: 10.1002/jbmr.2362

    18. Longitudinal HR-pQCT and Image Registration Detects Endocortical Bone Loss in Kidney Transplantation Patients

      Kyle K Nishiyama, Yves Pauchard, Lucas E Nikkel, Sapna Iyer, Chiyuan Zhang, Donald J McMahon, David Cohen, Steven K Boyd, Elizabeth Shane and Thomas L Nickolas

      Accepted manuscript online: 11 SEP 2014 04:20PM EST | DOI: 10.1002/jbmr.2358

    19. Rates of and Risk Factors for Trabecular and Cortical BMD Loss in Middle-Aged and Elderly African Ancestry Men

      Yahtyng Sheu, Clareann H. Bunker, Pallavi Jonnalagadda, Ryan K. Cvejkus, Allen L. Patrick, Victor W. Wheeler, Christopher L. Gordon and Joseph M. Zmuda

      Accepted manuscript online: 11 SEP 2014 04:18PM EST | DOI: 10.1002/jbmr.2359

    20. Bone Fracture Toughness and Strength Correlate with Collagen Cross-Link Maturity in a Dose-Controlled Lathyrism Mouse Model

      Erin M. B. McNerny, Bo Gong, Michael D. Morris and David H. Kohn

      Accepted manuscript online: 11 SEP 2014 04:14PM EST | DOI: 10.1002/jbmr.2356

    21. Relationship Between Pre-treatment Rate of Bone Loss and Bone Density Response to Once-Yearly ZOL: HORIZON-PFT Extension Study

      Richard Eastell, Steven Boonen, Felicia Cosman, Ian R Reid, Lisa Palermo, Steven R Cummings and Dennis M Black

      Accepted manuscript online: 11 SEP 2014 04:14PM EST | DOI: 10.1002/jbmr.2361

    22. A Novel Splice-Mutation in PLS3 Causes X-Linked Early-Onset Low-Turnover Osteoporosis

      Christine M. Laine, Maija Wessman, Sanna Toiviainen-Salo, Mari A. Kaunisto, Mervi K. Mäyränpää, Tero Laine, Minna Pekkinen, Heikki Kröger, Ville-Valtteri Välimäki, Matti J. Välimäki, Anna-Elina Lehesjoki and Outi Mäkitie

      Accepted manuscript online: 10 SEP 2014 04:05PM EST | DOI: 10.1002/jbmr.2355

    23. Growth and aging of proximal femoral bone – a study with women spanning three generations

      Qin Wang, Decai Chen, Shu Mei Cheng, Patrick Nicholson, Markku Alen and Sulin Cheng

      Accepted manuscript online: 6 SEP 2014 03:38AM EST | DOI: 10.1002/jbmr.2353

    24. FGF23 is endogenously phosphorylated in bone cells

      Iris Lindberg, Hong Weng Pang, Joseph P. Stains, David Clark, Austin J. Yang, Lynda Bonewald and Kevin Z. Li

      Accepted manuscript online: 6 SEP 2014 03:36AM EST | DOI: 10.1002/jbmr.2354


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