genesis

Cover image for Vol. 55 Issue 9

Edited By: Sally A. Moody

Online ISSN: 1526-968X

Just Published Articles

  1. DPFF-1 transcription factor deficiency causes the aberrant activation of MPK-1 and meiotic defects in the Caenorhabditis elegans germline

    Emmanuel Villanueva-Chimal, Laura S. Salinas, Laura P. Fernández-Cardenas, Gabriela Huelgas-Morales, Alejandro Cabrera-Wrooman and Rosa E. Navarro

    Accepted manuscript online: 23 SEP 2017 03:15AM EST | DOI: 10.1002/dvg.23072

  2. Selective expression of eGFP in mouse perivascular astrocytes by modification of the Mlc1 gene using T2A-based ribosome skipping

    Jordan J. Toutounchian and Joseph H. McCarty

    Accepted manuscript online: 20 SEP 2017 03:46AM EST | DOI: 10.1002/dvg.23071

  3. A new mouse line for cell ablation by diphtheria toxin subunit A controlled by a Cre-dependent FLEx switch

    Nicholas W. Plummer, Erica K. Ungewitter, Kathleen G. Smith, Humphrey H.-C. Yao and Patricia Jensen

    Version of Record online: 19 SEP 2017 | DOI: 10.1002/dvg.23067

  4. Axin2-mTurquoise2: A novel reporter mouse model for the detection of canonical Wnt signalling

    Jolanda. J. D. de Roo, Cor Breukel, Amiet R. Chhatta, Margot M. Linssen, Sandra A. Vloemans, Daniela Salvatori, Harald M. M. Mikkers, Sjef J. Verbeek and Frank J.T. Staal

    Version of Record online: 19 SEP 2017 | DOI: 10.1002/dvg.23068

  5. An X-linked Myh11-CreERT2 mouse line resulting from Y to X chromosome-translocation of the Cre allele

    Mingmei Liao, Junmei Zhou, Fen Wang, Yasmin H. Ali, Kelvin L. Chan, Fei Zou, Stefan Offermanns, Zhisheng Jiang and Zhihua Jiang

    Version of Record online: 16 SEP 2017 | DOI: 10.1002/dvg.23054

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Virtual Issues

Virtual Issue: Mouse Genetics and Development

genesis

This compilation of research articles and technology reports illustrates numerous recent advances in mouse developmental genetic tools that will be of great benefit to the research community. The Mouse Genetics and Development virtual issue articles are freely available online and will be updated periodically.

See these other Virtual Issues

Fly Genetics and Development

genesis Reviews

genesis Award Winners

Congratulations to the 2017 SDB genesis award winners!

Congratulations to the recipient of the genesis poster presentation prize at the 2017 Society for Developmental Biology meeting.

Fracesca

Francesca Tuazon (Laboratory of Dr. Mary Mullins – University of Pennsylvania): studies the mechanisms that drive the formation of the BMP morphogen gradient, which is essential to pattern dorsoventral axial tissues, in the zebrafish embryo. By quantifying the BMP signaling gradient, she showed that the activity of two metalloproteases, Tolloid and Bmp1a, are essential to establish the BMP gradient and uncovered a previously unappreciated role for their inhibitor, Sizzled in this process. Furthermore, she discovered that the BMP gradient changes shape dramatically during gastrulation and that Tolloid and Sizzled play region-specific roles in defining this new shape to correctly pattern posterior tissues. Together, these data position metalloprotease regulation as a central mechanism for modulating BMP signaling in space and time.




Congratulations to the recipients of the genesis best student and postdoc talk awards at the 2017 West Coast regional meeting of the Society for Developmental Bioiogy.

Raul Ramos

Raul Ramos (Plikus Lab - University of California, Irvine): "A cellular and developmental characterization of auricular cartilage."

Evgeny Kvon

Evgeny Kvon (Lawrence Berkeley National Laboratory): "Molecular basis of limb loss in snakes."




Congratulations to the 2017 SCGDB genesis award winners!

Congratulations to the recipients of the genesis best student poster awards at the 2017 meeting of the Society for Craniofacial Genetics and Developmental Bioiogy. They each received a complimentary one-year subscription to genesis.

First prize: Camilla Teng (University of Southern California): "Zebrafish model of Saethre-Chotzen Syndrome reveals genetic conservation despite shifts in tissue origins"

Second Prize: Bonnie K. Kircher (University of Florida): "Growing apart: characterizing the development of sexual dimorphism"

Third Prize: Brian J. Paul (University of Iowa): "Oral cleft patient-derived ARHGAP29 mutation causes lethality and oral adhesions in mice"

Honorable Mention Awardees: Kaylia Duncan (University of Iowa): "The role of znf750 in the gene regulatory network governing periderm differentiation"

Everett G. Hall (University of Kansas): "Moderate SPECC1L deficiency results in palate defects through changes in both oral epithelium and cranial neural crest derived palatal mesenchyme"

Sofia Pezoa (University of Colorado): "Craniofacial bone and cartilage development is dependent on histone acetylation"




Special Issues

Special Issue:
Xenopus: Advances and Emerging Technologies

genesis

Model animals are crucial to biomedical research. Among the commonly used model animals, the amphibian Xenopus has had tremendous impact because of its unique experimental advantages, cost effectiveness, and close evolutionary relationship with mammals as a tetrapod.

Click here to read the Special Issue for free.


Read these other recent Special Issues:

Single cell analysis in C. elegans

Model Organism Databases

Tunicate Biology

Left-Right Asymmetry: Advances and Enigmas

Developmental Biology of Sea Urchins

Chick Genomics

Free Teaching Tools

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