Cover image for Vol. 54 Issue 4

Edited By: Sally A. Moody

Online ISSN: 1526-968X

Author Guidelines

Effective with the 2012 volume, this journal will be published in an online-only format.


genesis employs a plagiarism detection system. By submitting your manuscript to this journal, you accept that your manuscript may be screened for plagiarism against previously published works.

NIH Public Access Mandate. genesis, The Journal of Genetics and Development is fully compliant with the NIH Public Access Mandate. For more information please visit our policy statement at

Author Resources. Please visit this enhanced suite of on-line tools for Wiley Online Library journal authors, featuring Article Tracking, E-mail Publication and Customized Research Tools.

Search Engine Optimization for Your Paper
Consult our SEO Tips for Authors page in order to maximize online discoverability for your published research. Included are tips for making your title and abstract SEO-friendly, choosing appropriate keywords, and promoting your research through social media.

Permission Request form

Peer Review Policy (2010)

Publication Ethics page

General Instructions for Submission
Conflict of Interest Disclosure
Description of Submission Types
Requirements for Manuscript Submission
Title Page
Figure Legends
Cover Illustrations
Additional Information and Data Handling
Note to NIH Grantees
Production Questions

General Instructions for Submission

1. Online submission is required at If you have not already done so, please create an account for yourself in the system by clicking on the "Create an Account" button. Please study the site's Instructions and Forms, and then let the system guide you through the submission process. If you have any questions, online help is available to you at

2. Files uploaded to the genesis online submission system are ultimately used in final production through a completely paperless system. We therefore ask for production-quality files at submission. The manuscript preparation guidelines below must be followed, otherwise manuscripts will be returned to the author without review.

3. All text pages must be double-spaced and have one-inch margins, including the abstract, text, references, and legends. Number all pages in sequence, beginning with the title page.

All Manuscripts submitted to genesis, The Journal of Genetics and Development must be submitted solely to this journal, may not have been published in any part or form (except as an abstract for a meeting) in another publication of any type, professional or lay, and become the property of the publisher. Prior publication includes deposition of all or part of the data in a publically-accessible preprint or poster repository. Questions regarding this policy should be directed to the Editor-in-Chief. Authors should note that genesis employs the "CrossCheck" software to detect plagiarism of previous publications. Therefore, authors are cautioned not to simply recycle previously published work in newly submitted manuscripts. No published material may be reproduced or published elsewhere without the written permission of the publisher and the author. The journal will not be responsible for the loss of manuscripts at any time. All statements in, or omissions from, published manuscripts are the responsibility of the authors, who will review proofs thoroughly before publication. Reprint order forms will be sent with page proofs. No page charges will be levied against authors or their institutions for publication in the journal.

If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions

For authors choosing OnlineOpen

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution License OAA

Creative Commons Attribution Non-Commercial License OAA

Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit:


genesis is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE) (

4. The editors of genesis offer two tracks for consideration of original submissions:

Track 1: Status quo—new submissions are considered for peer review as usual (see “Peer Review Policy”).
Track 2: If your manuscript has already been reviewed but rejected by another journal, you may submit to genesis your revised manuscript, the original reviews and a cover letter describing how you have responded to the previous journal’s referee comments. The Editor-in-Chief will then consider whether the previous critiques have been adequately addressed. She can make an immediate editorial decision on the acceptance of your manuscript without further review, or may seek advice from Associate Editors, members of the Editorial Board or outside referees. This track allows the Editor-in-Chief to expedite a quick decision on your manuscript.

Conflict of Interest Disclosure
Wiley-Blackwell requires that all authors disclose any potential sources of conflict of interest. Any interest or relationship, financial or otherwise, that might be perceived as influencing an author’s objectivity is considered a potential source of conflict of interest. These must be disclosed when directly relevant or indirectly related to the work that the authors describe in their manuscript. Potential sources of conflict of interest include but are not limited to patent or stock ownership, membership of a company board of directors, membership of an advisory board or committee for a company, and consultancy for or receipt of speaker’s fees from a company. The existence of a conflict of interest does not preclude publication in this journal.

If the authors have no conflict of interest to declare, they must also state this at submission. It is the responsibility of the corresponding author to review this policy with all authors and to collectively list in the cover letter to the Editor-in-Chief, in the manuscript (under the Acknowledgments section), and in the online submission system ALL pertinent commercial and other relationships.

Description of Submission Types:
 genesis, The Journal of Genetics and Development is an international journal devoted to a genetic understanding of all aspects of development in animal and plant systems. genesis particularly encourages manuscripts with a convergence of disciplines, including genetics, genomics, proteomics, computational modeling, and evolutionary biology. genesis highly encourages manuscripts that describe developmental mechanisms in diverse organisms, both animal and plant. Manuscripts can be submitted in one the four following formats:  

RESEARCH ARTICLES are full-length reports that experimentally address a developmental problem. Research Articles should advance the field of development by mechanistic discoveries and by elucidating gene function. Manuscripts reporting purely descriptive science must be justified as having of particular interest to the research community to be considered for the journal. Research Articles include in order: Title page, Abstract (up to 200 words), Introduction, Results, Methods, Acknowledgments, References, and Figure legends (if applicable).  

LETTERS are succinct, experiment-based research reports whose text is limited to 1,600 words (excluding Figure Legends, References and Methods) and four to six display items (Tables and Figures). Letters include in order: Title page, Abstract (up to 200 words), Text (combined Results and Discussion), Methods, Acknowledgments, References, and Figure legends (if applicable). The text has no subheadings. Up to 30 references may be cited.

TECHNOLOGY REPORTS are succinct reports that focus upon technology development and developmental genetics resources. Technology Reports will follow the same format as Letters. In addition, the following criteria will be used to evaluate the suitability of Technology Reports for publication in genesis:
• The technology or reagent must provide an advance in addressing a developmental problem or process. Describing transgenic animals that are useful only to an adult system or disease state will not be considered.
• If a transgenic line is reported, how this line is distinct from other published lines must be described.
• The developmental relevance of the technology/reagent needs to be experimentally demonstrated. This includes showing the expression of a reporter at various stages, including both whole mount and tissue section analyses. The demonstration that a ubiquitous Cre-deletion results in a phenotype already reported for a gene knock-out will not be not be sufficient.
• For new Cre-driver lines, evidence concerning the specificity and penetrance of the effects (i.e. weak or strong and whether activity is mosaic) and the length of time/stage before Cre activity is detected must be provided. There should be a proof of activity description.
• For transgenic lines, information should be provided whether there are any phenotype(s) associated with homozygosity for the transgene insertion.
• If a reagent or transgenic animal is described, it must be declared in the manuscript in the Methods section that it will be available to the research community upon acceptance of the manuscript.  

Submission of REVIEWS is encouraged. The topics of the manuscript are flexible, but they are intended to reach a broad audience of readers in developmental genetics—from investigators in the field, to students learning the material for the first time. Therefore, it is important that the reviews start generally or with a historical perspective to integrate the topic into a larger context. The bulk of the review should be a critical analysis of the current field and should end with important yet-unresolved questions, speculations, and directions for the field in the future. All other formats for the Review are as listed below for Manuscripts.

Requirements for Manuscript Submission

1. Title page. The manuscript should have an informative title that defines the major findings described within the work. Titles should not exceed 90 characters (including spaces), and should not include numbers, acronyms, abbreviations or punctuation (other than a colon if essential). The title page must include the names and affiliations of all authors, the institution at which the work was performed, the name and address for all correspondence, telephone, telex, or fax number must be present. Include a short title of not more than 40 characters to be used as a Running Head, and three-to-six Keywords (not used in the title), which will appear below the abstract. Note to NIH grantees: In order for Wiley-Blackwell to submit an accepted article to PubMed Central, grant support must be listed on the title page. Please see the Wiley NIH Public Access Mandate page for more information regarding Wiley-Blackwell’s full compliance to the NIH Public Access Mandate.

2. Abstract. This section should be a factual condensation of the entire work and should include statements of the problem, methods of study, results, and conclusions as appropriate. All quantitative data in the abstract must also appear in the manuscript text or tables. The abstract may not exceed 200 words.

3. Text. Text of Research Articles should follow the format: Title page, Abstract, Introduction, Results, Discussion, Methods, Acknowledgments, References, and Figure legends (if applicable). If the work includes data derived from human subjects, a statement that informed, written consent was obtained is mandatory. Use subheadings and paragraph titles whenever possible. Authors should ensure that idiomatic English is used prior to submission. All unusual abbreviations must be defined. We recommend that authors go to for gene/protein nomenclature guidelines. Abbreviate measurements (cm, ml) according to Style Manual for Biological journals, American Institute for Biological Sciences, 3900 Wisconsin Avenue, N.W., Washington, D.C. Submit your text in DOC, DOCX, or RTF format. Do not embed figures or tables in this document; you must submit figures and tables as separate files.

Authors in Japan please note: Wiley-Japan can provide authors in Japan with a list of recommended services to check and improve the English of their papers before submission. Please visit for more information.

Authors in China please note: Authors in China can visit the Author Resources site on for additional resources, including tips for English writing skills, and bilingual, short presentations on different topics of interest.

4. Acknowledgments: Place acknowledgments as the last element of the text, before references. These should be brief.

5. References. References should be cited in the text by the name and date system (when there are more than two authors, use only the first name and "et al."). In the final list, they should be in alphabetical order, and chronological for more than one reference with the same authorship. Use a letter suffix if more than one author reference is for the same year. Begin each reference with the names of all authors and the year of publication. For references to journals, give all author names, the titles of articles in full, abbreviate journal names according to the system used by Index Medicus, and provide inclusive pagination. For references to books, include all authors' names, chapter title (if any), editor (if any), book title, city of publication, publisher's name, and year of publication. In the following examples, note the punctuation; do not use all capitals, do not underline:

Journal articles
Mazmanian G, Kovshilovsky M, Yen D, Mohanty A, Mohanty S, Nee A, Nissen RM. 2010. The zebrafish dyrk1b gene is important for endoderm formation. genesis 48: 20-30.

Wagner RP, Maguire MP, Stallings RL. 1993. Chromosomes: A Synthesis. New York: Wiley-Liss. p 1-182.

Chapters in books
Kalantry S, Magnuson T. 2007. Epigenetic influences on gene expression pathways. In: Moody SA, editor. Principles of Developmental Genetics. New York: Elsevier. p 92-113.

6. Figure Legends. A descriptive legend completes an illustration and permits it to be useful without reference to the text. A legend must accompany each illustration and must define any abbreviations used therein. Legends must be typed double spaced on a separate list at the end of the manuscript.

7. Tables. Each table must have a self-explanatory title, be numbered in order of appearance with Arabic numerals, and be referenced in the text. Tables must be submitted as separate MS Word files with the titles and legends included. The body of the table should not contain horizontal or vertical rules; these will be added by genesis when necessary after the paper has been accepted for publication. Symbols and abbreviations should be defined immediately below the table in a legend (in double-spaced text).

8. Illustrations. All illustrations must be numbered in order of appearance with Arabic numerals. Figures divided into parts should be labeled with a lower-case, bold (a, b, and so on), in the same type size as used elsewhere in the figure. To ensure the highest quality production, upload figures as separate image files using TIFF or EPS formats only. Images should follow the minimum resolutions: 1200 dpi for black and white line art (simple bar graphs, charts, etc.); 600 dpi for combination halftones (black and white images that also contain labeling or thin lines); 300 dpi for halftones (black and white photographs). Figures created in Adobe Illustrator should be submitted in EPS format.
Color Illustrations. genesis now publishes in online-only format. Therefore, all color figures can be published at no cost to authors. For best reproduction, bright, clear colors should be used whenever possible. Color figures must be submitted with at least 300 dpi resolution. Note: Authors must still adhere to editorial guidelines regarding article length, including number and size of figures. In some cases, authors may be asked to remove non-critical figures and present them instead as online supplementary materials available from the article’s online abstract page. Such supporting information should be cited from the text appropriately.

9. Gene nomenclature. Gene names should be in agreement with the nomenclature utilized by the organism specific database (e.g., FlyBase, WormBase, Xenbase, ZFIN, MGI) and be in accord with GenBank (see Sequence Report to GenBank section below). If warranted by an unresolved dispute, unofficial names can be identified in parentheses at the first mention of the gene, in the methods and/or in the keywords list.

Cover Illustrations
Authors of manuscripts submitted to genesis, The Journal of Genetics and Development are encouraged to submit figures and corresponding descriptions for consideration for cover art of an issue. Every effort is made to use cover art related to an article within an issue, and thus authors are encouraged to submit images with the final manuscript submission. These images should be emailed directly to the Editor-in-Chief (, who will make the final decisions on cover illustrations.

Along with any revised files, you must also prepare and submit a response clearly outlining all changes made to the manuscript. Please provide in the "Author Response" section, a "point-by-point" summary of how each of the issues raised by the reviewer(s) were addressed. For each criticism raised, please provide: 1. The criticism from the reviewer. 2. The response and explanation of how the manuscript has been modified in response to the criticism. For ease of final review, we also ask that revisions to text be made in red font. Please note, any changes to supplementary material should NOT be denoted in red font. Please indicate any changes to supplementary material in your Author's Response ONLY. Additionally, revisions require PRODUCTION-READY files. Your text, tables and figures must adhere to our file format, size and image resolution requirements located in the Author Guidelines.

Additional Information and Data Handling

Sequence Report to GenBank. All sequence data must be submitted to GenBank in compliance with their nomenclature. Such data will not be published without the corresponding accession number.

Microarray Data. Microarray data must be deposited in the appropriate public database and must be accessible without restriction from the date of publication. An entry name or accession number must be included in the Materials and Methods section of the manuscript. Microarray data must be MIAME compliant (for guidelines please see

Research with vertebrate animals and humans. For research involving live vertebrates, experiments must comply with all relevant institutional and national animal welfare laws, guidelines and policies and/or be conducted under guidelines approved by an Institutional Animal Care and Use Committee or equivalent body and performed in accordance with the NIH and National Research Council’s publication “Guide for Care and Use of Laboratory Animals”. The institutional committee(s) overseeing such guidelines must be identified in the Materials and Methods section of the manuscript. If the work includes data derived from human subjects, a statement that informed written consent was obtained is mandatory and should be submitted with the cover letter. Authors must list the institutional committee(s) that has approved experiments involving human subjects or human tissue in the Material and Methods section of their manuscript and include with their submission a statement to confirm that informed consent was obtained from all subjects or tissue donors.

Free Table of Contents Alerts.
Sign-up for genesis Journal Content Alerts Follow the steps below to sign up for email table of contents alerts and be the first to know when new research has published.

1) Log into Wiley Online Library. If you are not already a registered user, you can create your profile now. Registration is free. If you are a new registrant, return to the journal homepage at

2) Select "Get New Content Alerts" from Journal Tools on the top of the left-hand side menu.

3) Submit your preferences and you are done. You will now receive an email when a new issue of DVG publishes.

Reprints: Reprints may be purchased at

Note to NIH Grantees: Pursuant to the NIH Public Access Mandate, Wiley-Blackwell will post the accepted version of the contributions authored by NIH grant-holders to PubMed Central upon acceptance. To expedite this, authors are asked to list their NIH grant support on the title page of the manuscript. The accepted version of a manuscript will be made publically available 12 months after publication. For further information, see

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