Advanced Engineering Materials
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
(Adv. Eng. Mater. 10/2011)
The Cover shows the multi-scale representation of the interactions between collagen fibrils and hydroxylated titanium oxide surfaces. Single contact points formed by individual residues, studied with quantum mechanical models, determine the adsorption behaviour of oligopeptides on flat surfaces. This in turn governs the adhesion of whole collagen nanofibrils, competing with the effects of surface roughness and intramolecular mechanical stiffness at larger length-scales, as captured by classical force-fields. Further details can be found in the article by S. Köppen et. al. on page 334.