Hepatology

Cover image for Vol. 63 Issue 2

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: Michael H. Nathanson

Impact Factor: 11.055

ISI Journal Citation Reports © Ranking: 2014: 5/76 (Gastroenterology & Hepatology)

Online ISSN: 1527-3350

Associated Title(s): Clinical Liver Disease, Liver Transplantation

VIEW

  1. 1 - 98
  1. Liver Failure, Cirrhosis and Portal Hypertension

    1. Recurrent Recessive Mutation in DGUOK Causes Idiopathic Non-Cirrhotic Portal Hypertension

      Sílvia Vilarinho, Sinan Sari, Güldal Yilmaz, Amy L. Stiegler, Titus J. Boggon, Dhanpat Jain, Gulen Akyol, Buket Dalgic, Murat Günel and Richard P. Lifton

      Accepted manuscript online: 13 FEB 2016 10:06PM EST | DOI: 10.1002/hep.28499

  2. Liver capsule

    1. Liver Capsule: Mechanisms Of Alcoholic Hepatitis

      Bernd Schnabl

      Accepted manuscript online: 11 FEB 2016 06:53AM EST | DOI: 10.1002/hep.28488

  3. Viral Hepatitis

    1. Is increased HCV case-finding combined with current or 8-12 week DAA therapy cost-effective in UK prisons? A prevention benefit analysis

      Natasha K. Martin, Peter Vickerman, Iain F. Brew, Joan Williamson, Alec Miners, William L. Irving, Sushma Saksena, Sharon J. Hutchinson, Sema Mandal, Eamonn O'Moore and Matthew Hickman

      Accepted manuscript online: 10 FEB 2016 10:36PM EST | DOI: 10.1002/hep.28497

  4. Liver capsule

    1. Liver Capsule: Molecular-based signatures in hepatocellular carcinoma

      Amanda Craig and Augusto Villanueva

      Accepted manuscript online: 9 FEB 2016 03:17AM EST | DOI: 10.1002/hep.28489

  5. Autoimmune, Cholestatic and Biliary Disease

    1. FoxO3 inactivation promotes human cholangiocarcinoma tumorigenesis and chemoresistance via Keap1-Nrf2 signaling

      Li Guan, Lei Zhang, Zhicheng Gong, Xiaonan Hou, Yuxiu Xu, Xinhua Feng, Hongyang Wang and Han You

      Accepted manuscript online: 9 FEB 2016 03:17AM EST | DOI: 10.1002/hep.28496

  6. Steatohepatitis and Metabolic Liver Disease

    1. Genome-wide Association Study in Mice Identifies Loci Affecting Liver-related Phenotypes Including Sel1l Influencing Serum Bile Acids

      Wei Wu, Ami Patel, Kaisa Kyöstilä, Hannes Lohi, Nikol Mladkova, Krzysztof Kiryluk, Xiaoyun Sun, Jay H. Lefkowitch, Howard J. Worman and Ali G. Gharavi

      Accepted manuscript online: 9 FEB 2016 03:16AM EST | DOI: 10.1002/hep.28495

  7. Comments from the Editors

    1. “What's next for hepatitis C virus research?”

      Brett D. Lindenbach

      Accepted manuscript online: 8 FEB 2016 05:25AM EST | DOI: 10.1002/hep.28494

  8. Liver Biology and Pathobiology

    1. Keratins: Biomarkers and modulators of apoptotic and necrotic cell death in the liver

      Nam-On Ku, Pavel Strnad, Heike Bantel and M. Bishr Omary

      Accepted manuscript online: 8 FEB 2016 05:22AM EST | DOI: 10.1002/hep.28493

  9. Liver Injury and Regeneration

    1. Neurologic cues modulate immune-mediated liver injury and regeneration

      Benjamin L. Woolbright and Hartmut Jaeschke

      Accepted manuscript online: 8 FEB 2016 05:22AM EST | DOI: 10.1002/hep.28490

    2. P2X1 regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration

      Ramesh Kudira, Thomas Malinka, Andreas Kohler, Michel Dosch, Mercedes Gomez de Agüero, Nicolas Melin, Stefanie Haegele, Patrick Starlinger, Niran Maharjan, Smita Saxena, Adrian Keogh, Deborah Stroka, Daniel Candinas and Guido Beldi

      Accepted manuscript online: 8 FEB 2016 05:17AM EST | DOI: 10.1002/hep.28492

  10. Viral Hepatitis

    1. Retreatment with sofosbuvir and simeprevir of patients with HCV GT1 or 4 who previously failed a daclatasvir-containing regimen

      Christophe Hézode, Stéphane Chevaliez, Giovanna Scoazec, Alexandre Soulier, Anne Varaut, Magali Bouvier-Alias, Isaac Ruiz, Françoise Roudot-Thoraval, Ariane Mallat, Cyrille Féray and Jean-Michel Pawlotsky

      Accepted manuscript online: 8 FEB 2016 05:15AM EST | DOI: 10.1002/hep.28491

  11. Steatohepatitis and Metabolic Liver Disease

    1. Development and validation of a noninvasive prediction model for nonalcoholic steatohepatitis resolution after lifestyle intervention

      Eduardo Vilar-Gomez, Ali Yasells-Garcia, Yadina Martinez-Perez, Luis Calzadilla-Bertot, Ana Torres-Gonzalez, Bienvenido Gra-Oramas, Licet Gonzalez-Fabian, Oscar Villa-Jimenez, Scott L. Friedman, Moises Diago and Manuel Romero-Gomez

      Accepted manuscript online: 5 FEB 2016 10:48AM EST | DOI: 10.1002/hep.28484

  12. Hepatobiliary Malignancies

  13. Correspondence

    1. Reply: Acute HEV infection in HIV positive men and women in Nepal: Not quite a rare entity

      Mark H. Kuniholm and Kenrad E. Nelson

      Accepted manuscript online: 4 FEB 2016 06:05PM EST | DOI: 10.1002/hep.28483

  14. Liver Injury and Regeneration

    1. JNK mediates mouse liver injury through a novel Sab (SH3BP5) dependent pathway leading to inactivation of intramitochondrial Src

      Sanda Win, Tin Aung Than, Robert Win Maw Min, Mariam Aghajan and Neil Kaplowitz

      Accepted manuscript online: 4 FEB 2016 06:04PM EST | DOI: 10.1002/hep.28486

  15. Steatohepatitis and Metabolic Liver Disease

    1. Hepatic mitochondrial dysfunction in non-alcoholic steatohepatitis: Read-out or reason?

      Jonel Trebicka and Robert Schierwagen

      Accepted manuscript online: 4 FEB 2016 06:04PM EST | DOI: 10.1002/hep.28482

  16. Correspondence

    1. GNPAT variant is associated with iron phenotype in healthy Taiwanese women: A population without the HFE C282Y mutation

      Shu-Chen Hsiao, Chien-Te Lee and Sung-Nan Pei

      Accepted manuscript online: 4 FEB 2016 06:04PM EST | DOI: 10.1002/hep.28481

  17. Hepatobiliary Malignancies

    1. Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype

      Matthias S. Matter, Jens U. Marquardt, Jesper B. Andersen, Cristina Quintavalle, Nikolay Korokhov, Jim K. Stauffer, Kosuke Kaji, Thomas Decaens, Luca Quagliata, Fathi Elloumi, Tanya Hoang, Alfredo Molinolo, Elizabeth A. Conner, Achim Weber, Matthias Heikenwalder, Valentina M. Factor and Snorri S. Thorgeirsson

      Accepted manuscript online: 4 FEB 2016 06:03PM EST | DOI: 10.1002/hep.28487

  18. Correspondence

    1. Reply to: GNPAT variant is associated with iron phenotype in healthy Taiwanese women: A population without the HFE C282Y mutation

      Christine E. McLaren, James C. Barton, V. Nathan Subramaniam, Grant A. Ramm, Pradyumna D. Phatak, Mary J. Emond, Lyle C. Gurrin, Paul C. Adams, Lawrie W. Powell, Gregory J. Anderson and Gordon D. McLaren

      Accepted manuscript online: 4 FEB 2016 05:55PM EST | DOI: 10.1002/hep.28479

  19. Viral Hepatitis

    1. Acute HEV infection in HIV positive men and women in Nepal: Not quite a rare entity

      Birendra Gupta, Ananta Shrestha, Anurag Adhikari, Thupten Lama and Binaya Sapkota

      Accepted manuscript online: 4 FEB 2016 05:55PM EST | DOI: 10.1002/hep.28480

  20. Hepatobiliary Malignancies

    1. Protein tyrosine phosphatase 1B dephosphorylates PITX1 and regulates p120RasGAP in hepatocellular carcinoma

      Wei-Tien Tai, Yao-Li Chen, Pei-Yi Chu, Li-Ju Chen, Man-Hsin Hung, Chung-Wai Shiau, Jui-Wen Huang, Ming-Hsien Tsai and Kuen-Feng Chen

      Accepted manuscript online: 3 FEB 2016 04:53PM EST | DOI: 10.1002/hep.28478

  21. Clinical Perspectives in Hepatology

  22. Liver Failure, Cirrhosis and Portal Hypertension

    1. A low-cost, user-friendly EEG recording system for the assessment of hepatic encephalopathy

      Schiff Sami, Casa Mariella, Di Caro Valeria, Aprile Daniele, Spinelli Giuseppe, De Rui Michele, Angeli Paolo, Amodio Piero and Montagnese Sara

      Accepted manuscript online: 2 FEB 2016 04:52AM EST | DOI: 10.1002/hep.28477

  23. Liver Biology and Pathobiology

    1. Broadening the implications of gene discovery

      Eve A. Roberts

      Accepted manuscript online: 28 JAN 2016 06:17PM EST | DOI: 10.1002/hep.28474

  24. Viral Hepatitis

    1. Daclatasvir, Sofosbuvir, and Ribavirin for Hepatitis C Virus Genotype 3 and Advanced Liver Disease: A Randomized Phase III Study (ALLY-3+)

      Vincent Leroy, Peter Angus, Jean-Pierre Bronowicki, Greg J. Dore, Christophe Hezode, Stephen Pianko, Stanislas Pol, Katherine Stuart, Edmund Tse, Fiona McPhee, Rafia Bhore, Maria Jesus Jimenez-Exposito and Alexander J Thompson

      Accepted manuscript online: 28 JAN 2016 06:16PM EST | DOI: 10.1002/hep.28473

    2. Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes

      Mohammed Eslam, Alessandra Mangia, Thomas Berg, Henry Lik Yuen Chan, William L. Irving, Gregory J. Dore, Maria Lorena Abate, Elisabetta Bugianesi, Leon A. Adams, Mustafa A.M. Najim, Luca Miele, Martin Weltman, Lindsay Mollison, Wendy Cheng, Stephen Riordan, Janett Fischer, Manuel Romero-Gomez, Ulrich Spengler, Jacob Nattermann, Antony Rahme, David Sheridan, David R. Booth, Duncan McLeod, Elizabeth Powell, Christopher Liddle, Mark W. Douglas, David van der Poorten, Jacob George and for the International Liver Disease Genetics Consortium (ILDGC)

      Accepted manuscript online: 28 JAN 2016 06:12PM EST | DOI: 10.1002/hep.28475

  25. Steatohepatitis and Metabolic Liver Disease

    1. Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, ER stress and lipogenesis and is regulated by HNF4α

      Yuanyuan Li, Munaf Zalzala, Kavita Jadhav, Yang Xu, Takhar Kasumov, Liya Yin and Yanqiao Zhang

      Accepted manuscript online: 25 JAN 2016 03:26AM EST | DOI: 10.1002/hep.28472

  26. Liver Failure, Cirrhosis and Portal Hypertension

    1. Challenge accepted: Confronting readmissions for our patients with cirrhosis

      Elliot B. Tapper

      Accepted manuscript online: 25 JAN 2016 03:26AM EST | DOI: 10.1002/hep.28471

  27. Clinical Observations in Hepatology

  28. Steatohepatitis and Metabolic Liver Disease

    1. A new HIF-1α/RANTES driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF

      Mei Yee Koh, Mihai Gagea, Timothy Sargis, Robert Lemos Jr, Geoffrey Grandjean, Adriana Charbono, Vasileos Bekiaris, John Sedy, Galina Kiriakova, Xiuping Liu, Lewis R. Roberts, Carl Ware and Garth Powis

      Accepted manuscript online: 22 JAN 2016 06:40PM EST | DOI: 10.1002/hep.28468

  29. Liver Injury and Regeneration

    1. The plastic cellular states of liver cells: Are EpCAM and Lgr5 fit for purpose?

      Meritxell Huch and Laurent Dollé

      Accepted manuscript online: 22 JAN 2016 06:37PM EST | DOI: 10.1002/hep.28469

  30. Correspondence

  31. Liver Failure, Cirrhosis and Portal Hypertension

    1. Natural history and management of esophagogastric varices in chronic non-cirrhotic non-tumoral portal vein thrombosis

      Carlos Noronha Ferreira, Susana Seijo, Aurelie Plessier, Gilberto Silva-Junior, Fanny Turon, Pierre-Emmanuel Rautou, Anna Baiges, Christophe Bureau, Jaime Bosch, Virginia Hernández-Gea, Dominique Valla and Juan-Carlos García-Pagan

      Accepted manuscript online: 22 JAN 2016 05:28AM EST | DOI: 10.1002/hep.28466

  32. Viral Hepatitis

    1. Simeprevir Plus Sofosbuvir (12 and 8 Weeks) in HCV Genotype 1-Infected Patients Without Cirrhosis: OPTIMIST-1, a Phase 3, Randomized Study

      Paul Kwo, Norman Gitlin, Ronald Nahass, David Bernstein, Kyle Etzkorn, Sergio Rojter, Eugene Schiff, Mitchell Davis, Peter Ruane, Ziad Younes, Ronald Kalmeijer, Rekha Sinha, Monika Peeters, Oliver Lenz, Bart Fevery, Guy De La Rosa, Jane Scott and James Witek

      Accepted manuscript online: 22 JAN 2016 05:27AM EST | DOI: 10.1002/hep.28467

    2. Novel Quantification of TDF adherence in HIV-hepatitis B co-infected patients with incomplete HBV viral suppression

      Tammy C. Wong, Audrey Lan, Jennifer Kiser, Peter L. Anderson, Keyur Patel, Hans Tillman and Susanna Naggie

      Accepted manuscript online: 21 JAN 2016 06:06PM EST | DOI: 10.1002/hep.28461

  33. Liver Injury and Regeneration

  34. Correspondence

    1. Reply to: Novel Quantification of TDF adherence in HIV-hepatitis B co-infected patients with incomplete HBV viral suppression

      Anders Boyd, Gilles Peytavin and Karine Lacombe

      Accepted manuscript online: 19 JAN 2016 06:24PM EST | DOI: 10.1002/hep.28463

  35. Hepatobiliary Malignancies

  36. Clinical Observations in Hepatology

    1. A Pilot Study of Operational Tolerance with a Regulatory T Cell-Based Cell Therapy in Living Donor Liver Transplantation

      Satoru Todo, Kenichiro Yamashita, Ryoichi Goto, Masaaki Zaitsu, Akihisa Nagatsu, Tetsu Oura, Masaaki Watanabe, Takeshi Aoyagi, Tomomi Suzuki, Tsuyoshi Shimamura, Toshiya Kamiyama, Norihiro Sato, Junichi Sugita, Kanako Hatanaka, Hisashi Bashuda, Sonoko Habu, Anthony J. Demetris and Ko Okumura

      Accepted manuscript online: 16 JAN 2016 03:43AM EST | DOI: 10.1002/hep.28459

  37. Viral Hepatitis

    1. Liver mortality attributable to chronic hepatitis C virus infection in Denmark and Scotland – using spontaneous resolvers as the benchmark comparator

      H. Innes, S.J. Hutchinson, N. Obel, P.B. Christensen, E.J. Aspinall, D. Goldberg, H. Krarup, S.A. Mcdonald, A. Mcleod, A. Weir and L.H. Omland

      Accepted manuscript online: 16 JAN 2016 03:43AM EST | DOI: 10.1002/hep.28458

    2. Reply

      Anna S. Lok

      Accepted manuscript online: 16 JAN 2016 03:43AM EST | DOI: 10.1002/hep.28457

  38. Steatohepatitis and Metabolic Liver Disease

    1. Interleukin-1 and inflammasomes in ALD/AAH and NAFLD/NASH

      Herbert Tilg, Alexander R Moschen and Gyongyi Szabo

      Accepted manuscript online: 16 JAN 2016 03:41AM EST | DOI: 10.1002/hep.28456

  39. Hepatobiliary Malignancies

    1. Lipiodol transarterial chemoembolization for hepatocellular carcinoma: A systematic review of efficacy and safety data

      Riccardo Lencioni, Thierry de Baere, Michael C. Soulen, William S. Rilling and Jean-Francois H. Geschwind

      Accepted manuscript online: 13 JAN 2016 05:09AM EST | DOI: 10.1002/hep.28453

    2. miR-28-5p-IL-34-Macrophage Feedback Loop Modulates Hepatocellular Carcinoma Metastasis

      Shao-Lai Zhou, Zhi-Qiang Hu, Zheng-Jun Zhou, Zhi Dai, Zheng Wang, Ya Cao, Jia Fan, Xiao-Wu Huang and Jian Zhou

      Accepted manuscript online: 11 JAN 2016 05:55PM EST | DOI: 10.1002/hep.28445

  40. Viral Hepatitis

    1. You have full text access to this OnlineOpen article
      Daclatasvir With Sofosbuvir and Ribavirin for HCV Infection With Advanced Cirrhosis or Post-Liver Transplant Recurrence

      Fred Poordad, Eugene R. Schiff, John M. Vierling, Charles Landis, Robert J. Fontana, Rong Yang, Fiona McPhee, Eric A. Hughes, Stephanie Noviello and Eugene S. Swenson

      Accepted manuscript online: 11 JAN 2016 05:54PM EST | DOI: 10.1002/hep.28446

  41. Hepatobiliary Malignancies

    1. Should hepatic dysplasia nodules and regenerative nodules be regarded as pre-malignant lesions and treated?

      Lei Zhao, Linda L Wong, Xuetao Shi and Junfang Ji

      Accepted manuscript online: 11 JAN 2016 05:54PM EST | DOI: 10.1002/hep.28444

  42. Liver Failure, Cirrhosis and Portal Hypertension

    1. Echinocandins vs fluconazole in the treatment of spontaneous fungal peritonitis

      Salvatore Piano and Paolo Angeli

      Accepted manuscript online: 11 JAN 2016 05:54PM EST | DOI: 10.1002/hep.28443

  43. Liver Biology and Pathobiology

    1. Physiological Ranges of Matrix Rigidity Modulate Primary Mouse Hepatocyte Function In Part Through Hepatocyte Nuclear Factor 4 Alpha

      Seema S. Desai, Jason C. Tung, Vivian X. Zhou, James P. Grenert, Yann Malato, Milad Rezvani, Regina Español-Suñer, Holger Willenbring, Valerie M. Weaver and Tammy T. Chang

      Accepted manuscript online: 11 JAN 2016 05:53PM EST | DOI: 10.1002/hep.28450

  44. Correspondence

    1. Reply

      Sylvie Deuffic-Burban and Yazdan Yazdanpanah

      Accepted manuscript online: 11 JAN 2016 05:53PM EST | DOI: 10.1002/hep.28447

    2. Pre-emptive therapy of spontaneous fungal peritonitis

      Marco Fiore, Lorenzo Andreana and S. Leone

      Accepted manuscript online: 11 JAN 2016 05:53PM EST | DOI: 10.1002/hep.28448

    3. Cure prevents more than transmission of HCV

      Harel Dahari, Scot J. Cotler and Jordan J. Feld

      Accepted manuscript online: 11 JAN 2016 05:52PM EST | DOI: 10.1002/hep.28449

  45. Viral Hepatitis

    1. Discontinuation of oral antivirals in chronic hepatitis b: A systematic review

      George Papatheodoridis, Ioannis Vlachogiannakos, Evangelos Cholongitas, Karsten Wursthorn, Christos Thomadakis, Giota Touloumi and Jörg Petersen

      Accepted manuscript online: 11 JAN 2016 03:37AM EST | DOI: 10.1002/hep.28438

    2. A nationwide survey of hepatitis E virus infection in French blood donors

      Jean Michel Mansuy, Pierre Gallian, Chloé Dimeglio, Karine Saune, Catherine Arnaud, Bertrand Pelletier, Pascal Morel, Dominique Legrand, Pierre Tiberghien and Jacques Izopet

      Accepted manuscript online: 11 JAN 2016 03:36AM EST | DOI: 10.1002/hep.28436

  46. Liver Injury and Regeneration

    1. Akt-FoxO1 axis controls liver regeneration

      Leila Valanejad and Nikolai Timchenko

      Accepted manuscript online: 11 JAN 2016 03:35AM EST | DOI: 10.1002/hep.28440

  47. Steatohepatitis and Metabolic Liver Disease

    1. Clinical advances in pediatric nonalcoholic fatty liver disease

      Jeffrey B. Schwimmer

      Accepted manuscript online: 11 JAN 2016 03:35AM EST | DOI: 10.1002/hep.28441

  48. Liver Biology and Pathobiology

    1. Shutting off inflammation: A novel switch on hepatic stellate cells

      Francisco Javier Cubero

      Accepted manuscript online: 11 JAN 2016 03:34AM EST | DOI: 10.1002/hep.28442

    2. Canonical NF-κB signaling in hepatocytes acts as a tumor-suppressor in HBV surface antigen-driven HCC by controlling the UPR

      Yoshiaki Sunami, Marc Ringelhan, Enikö Kokai, Miao Lu, Tracy O'Connor, Anna Lorentzen, Achim Weber, Ann-Katrin Rodewald, Beat Müllhaupt, Luigi Terracciano, Sarah Gul, Sebastian Wissel, Frank Leithäuser, Daniel Krappmann, Petra Riedl, Daniel Hartmann, Reinhold Schirmbeck, Pavel Strnad, Norbert Hüser, Jörg Kleeff, Helmut Friess, Roland M Schmid, Fabian Geisler, Thomas Wirth and Mathias Heikenwalder

      Accepted manuscript online: 11 JAN 2016 03:34AM EST | DOI: 10.1002/hep.28435

  49. Hepatobiliary Malignancies

    1. CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors

      Ming Liu, Leilei Chen, Ning-Fang Ma, Raymond Kwok Kei Chow, Yan Li, Yangyang Song, Tim Hon Man Chan, Shuo Fang, Xiaodong Yang, Shaoyan Xi, Lingxi Jiang, Yun Li, Ting-Ting Zeng, Yan Li, Yun-Fei Yuan and Xin-Yuan Guan

      Accepted manuscript online: 11 JAN 2016 03:33AM EST | DOI: 10.1002/hep.28437

  50. Liver capsule

    1. IRFs in hepatocytes pathophysiology

      Pi-Xiao Wang, Xiao-Jing Zhang and Hongliang Li

      Accepted manuscript online: 28 DEC 2015 05:59PM EST | DOI: 10.1002/hep.28433

  51. Liver Failure, Cirrhosis and Portal Hypertension

    1. Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells

      Yumin Oh, Ogyi Park, Magdalena Swierczewska, James P. Hamilton, Jong-Sung Park, Tae Hyung Kim, Sung-Mook Lim, Hana Eom, Dong Gyu Jo, Choong-Eun Lee, Raouf Kechrid, Panagiotis Mastorakos, Clark Zhang, Sei Kwang Hahn, Ok-Cheol Jeon, Youngro Byun, Kwangmeyung Kim, Justin Hanes, Kang Choon Lee, Martin G. Pomper, Bin Gao and Seulki Lee

      Accepted manuscript online: 28 DEC 2015 05:58PM EST | DOI: 10.1002/hep.28432

  52. Viral Hepatitis

    1. Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge

      Isabelle Desombere, Samira Fafi-Kremer, Freya Van Houtte, Patrick Pessaux, Ali Farhoudi, Laura Heydmann, Lieven Verhoye, Sarah Cole, Jane A. McKeating, Geert Leroux-Roels, Thomas F. Baumert, Arvind H. Patel and Philip Meuleman

      Accepted manuscript online: 28 DEC 2015 05:51PM EST | DOI: 10.1002/hep.28428

    2. The burden of hepatitis C to the United States medicare system in 2009: Descriptive and economic characteristics

      David B. Rein, Joshua Borton, Danielle K. Liffmann and John S. Wittenborn

      Accepted manuscript online: 28 DEC 2015 03:29AM EST | DOI: 10.1002/hep.28430

  53. Clinical Observations in Hepatology

    1. Noncirrhotic complete obliterative portal vein thrombosis: novel management using trans-splenic TIPS with portal vein recanalization

      Joseph Ralph Kallini, Ahmed Gabr, Laura Kulik, Daniel Ganger, Robert Lewandowski, Bartley Thornburg and Riad Salem

      Accepted manuscript online: 28 DEC 2015 03:29AM EST | DOI: 10.1002/hep.28429

  54. Steatohepatitis and Metabolic Liver Disease

    1. Global Epidemiology of Non-Alcoholic Fatty Liver Disease–Meta-Analytic Assessment of Prevalence, Incidence and Outcomes

      Zobair M. Younossi, Aaron B Koenig, Dinan Abdelatif, Yousef Fazel, Linda Henry and Mark Wymer

      Accepted manuscript online: 28 DEC 2015 03:28AM EST | DOI: 10.1002/hep.28431

  55. Liver Failure, Cirrhosis and Portal Hypertension

    1. Authors reply to Dr N. Intagliata et al.

      Lesley De Pietri, Marcello Bianchini, Guadalupe Garcia-Tsao and Erica Villa

      Accepted manuscript online: 24 DEC 2015 06:29PM EST | DOI: 10.1002/hep.28427

  56. Correspondence

    1. Prediction of bleeding in cirrhosis patients: Is the forecast any clearer?

      NM Intagliata, SH Caldwell, RJ Porte and T Lisman

      Accepted manuscript online: 24 DEC 2015 06:28PM EST | DOI: 10.1002/hep.28426

  57. Viral Hepatitis

    1. Genetic variation in STAT4 predicts response to interferon-α therapy for hepatitis B e antigen-positive chronic hepatitis B

      De-Ke Jiang, Xiaopan Wu, Ji Qian, Xiao-Pin Ma, Jingmin Yang, Zhuo Li, Runhua Wang, Li Sun, Fang Liu, Pengyin Zhang, Xilin Zhu, Jia Wu, Kangmei Chen, Carly Conran, S. Lilly Zheng, Daru Lu, Long Yu, Ying Liu and Jianfeng Xu

      Accepted manuscript online: 24 DEC 2015 11:27AM EST | DOI: 10.1002/hep.28423

    2. Simeprevir plus sofosbuvir in patients with chronic hepatitis C virus genotype 1 infection and cirrhosis: A Phase 3 study (OPTIMIST-2)

      Eric Lawitz, Gary Matusow, Edwin DeJesus, Eric M. Yoshida, Franco Felizarta, Reem Ghalib, Eliot Godofsky, Robert W. Herring, Gary Poleynard, Aasim Sheikh, Hillel Tobias, Marcelo Kugelmas, Ronald Kalmeijer, Monika Peeters, Oliver Lenz, Bart Fevery, Guy De La Rosa, Jane Scott, Rekha Sinha and James Witek

      Accepted manuscript online: 24 DEC 2015 11:26AM EST | DOI: 10.1002/hep.28422

  58. Hepatology Elsewhere

    1. Towards new standards for non-invasive measuring of portal pressure?

      Søren Møller

      Accepted manuscript online: 24 DEC 2015 11:26AM EST | DOI: 10.1002/hep.28424

  59. Viral Hepatitis

    1. Safety and Efficacy of Ledipasvir/Sofosbuvir for the Treatment of Genotype 1 Hepatitis C in Subjects Aged 65 Years or Older

      Sammy Saab, Sarah H. Park, Masashi Mizokami, Masao Omata, Alessandra Mangia, Ed Eggleton, Yanni Zhu, Steven J. Knox, Phil Pang, Mani Subramanian, Kris Kowdley and Nezam H. Afdhal

      Accepted manuscript online: 24 DEC 2015 11:26AM EST | DOI: 10.1002/hep.28425

  60. Hepatobiliary Malignancies

    1. You have full text access to this OnlineOpen article
  61. Correspondence

    1. CD14+ regulatory Dendritic Cells in Hepatocellular Carcinoma and Cirrhotic patients

      Shiroh Tanoue and David E. Kaplan

      Accepted manuscript online: 24 DEC 2015 11:22AM EST | DOI: 10.1002/hep.28419

  62. Hepatobiliary Malignancies

    1. Acetyl-CoA carboxylase α promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients

      Ming-Da Wang, Han Wu, Gong-Bo Fu, Hui-Lu Zhang, Xu Zhou, Liang Tang, Li-Wei Dong, Chen-Jie Qin, Shuai Huang, Ling-Hao Zhao, Min Zeng, Meng-Chao Wu, He-Xin Yan and Hong-Yang Wang

      Accepted manuscript online: 23 DEC 2015 10:45AM EST | DOI: 10.1002/hep.28415

  63. Steatohepatitis and Metabolic Liver Disease

  64. Liver Failure, Cirrhosis and Portal Hypertension

    1. Histidine-rich glycoprotein promotes macrophage activation and inflammation in chronic liver disease

      Matthias Bartneck, Viktor Fech, Josef Ehling, Olivier Govaere, Klaudia Theresa Warzecha, Kanishka Hittatiya, Mihael Vucur, Jérémie Gautheron, Tom Luedde, Christian Trautwein, Twan Lammers, Tania Roskams, Willi Jahnen-Dechent and Frank Tacke

      Accepted manuscript online: 23 DEC 2015 10:44AM EST | DOI: 10.1002/hep.28418

  65. Correspondence

    1. Meta-regression in network meta-analysis of aggregate data

      Siddharth Singh, Rohan Khera, M. Hassan Murad and Rohit Loomba

      Accepted manuscript online: 21 DEC 2015 06:37PM EST | DOI: 10.1002/hep.28412

  66. Liver Failure, Cirrhosis and Portal Hypertension

    1. The Three-Month Readmission Rate Remains Unacceptably High in a Large North American Cohort of Cirrhotic Patients

      Jasmohan S. Bajaj, K. Rajender Reddy, Puneeta Tandon, Florence Wong, Patrick S. Kamath, Guadalupe Garcia-Tsao, Benedict Maliakkal, Scott W. Biggins, Paul J. Thuluvath, Michael B. Fallon, Ram M. Subramanian, Hugo Vargas, Leroy R. Thacker, Jacqueline G O'Leary and on behalf of NACSELD

      Accepted manuscript online: 21 DEC 2015 10:57AM EST | DOI: 10.1002/hep.28414

  67. Correspondence

    1. Drug-related covariates should be considered in Bayesian network meta-analysis of pharmacological interventions

      Jie Wei, Lei Fu and Shi-fang Peng

      Accepted manuscript online: 19 DEC 2015 03:43AM EST | DOI: 10.1002/hep.28413

  68. Hepatobiliary Malignancies

    1. Aspartate β-hydroxylase modulates cellular senescence via glycogen synthase kinase 3β in hepatocellular carcinoma

      Yoshifumi Iwagami, Chiung-Kuei Huang, Mark J. Olsen, John-Michael Thomas, Grace Jang, Miran Kim, Qiushi Lin, Rolf I. Carlson, Carl E. Wagner, Xiaoqun Dong and Jack R. Wands

      Accepted manuscript online: 19 DEC 2015 03:26AM EST | DOI: 10.1002/hep.28411

    2. Theranostical nanosystem-mediated identification of an oncogene and highly effective therapy in hepatocellular carcinoma

      Yu Guo, Jing Wang, Lu Zhang, Shunli Shen, Ruomi Guo, Yang Yang, Wenjie Chen, Yiru Wang, Guihua Chen and Xintao Shuai

      Accepted manuscript online: 17 DEC 2015 04:58AM EST | DOI: 10.1002/hep.28409

  69. Correspondence

    1. Anti-CD20 monoclonal antibody for the treatment of patients with autoimmune hepatitis

      Kathie Beland and Fernando Alvarez

      Accepted manuscript online: 17 DEC 2015 04:52AM EST | DOI: 10.1002/hep.28407

  70. Autoimmune, Cholestatic and Biliary Disease

    1. MDR3 mutation analysis: A step closer to precision medicine

      Jorge A Bezerra

      Accepted manuscript online: 17 DEC 2015 04:43AM EST | DOI: 10.1002/hep.28408

  71. Viral Hepatitis

  72. Steatohepatitis and Metabolic Liver Disease

    1. Activation of LXR/RXR pathway ameliorates liver disease in atp7b-/- (wilson disease) mice

      JP Hamilton, L Koganti, A Muchenditsi, VS Pendyala, D Huso, J Hankin, RC Murphy, D Huster, U Merle, C Mangels, N Yang, JJ Potter, E Mezey and S Lutsenko

      Accepted manuscript online: 17 DEC 2015 04:42AM EST | DOI: 10.1002/hep.28406

  73. Correspondence

    1. Diabetes prevention through prevention of hepatitis B

      James Lin, Horng-Yih Ou, Lee-Ming Chuang and Ken C. Chiu

      Accepted manuscript online: 13 DEC 2015 11:21PM EST | DOI: 10.1002/hep.28399

  74. Steatohepatitis and Metabolic Liver Disease

    1. Therapeutic potential of NAD+ for NASH

      Philippe Gual and Catherine Postic

      Accepted manuscript online: 13 DEC 2015 01:45AM EST | DOI: 10.1002/hep.28383

  75. Viral Hepatitis

    1. Vaccine-induced HCV-specific CD8+ T cells do not always help

      Dominik Wieland and Robert Thimme

      Accepted manuscript online: 10 DEC 2015 07:28PM EST | DOI: 10.1002/hep.28388

    2. Differences in hepatitis viral etiology of hepatocellular carcinoma in Taiwan and China

      Ding-Shinn Chen, Yun-Fan Liaw, Chien-Jen Chen, Jaw-Ching Wu, Wan-Long Chuang, Cheng-Yuan Peng and Rong-Nan Chien

      Accepted manuscript online: 10 DEC 2015 07:26PM EST | DOI: 10.1002/hep.28378

    3. Care delivery and outcomes among U.S. veterans with hepatitis B: A national cohort study

      Marina Serper, Gina Choi, Kimberly A. Forde and David E. Kaplan

      Accepted manuscript online: 11 NOV 2015 06:37PM EST | DOI: 10.1002/hep.28340

  76. Steatohepatitis and Metabolic Liver Disease

    1. NAFLD, cardiovascular outcomes and mortality in patients undergoing coronary angiogram

      Giovanni Targher and Christopher D. Byrne

      Accepted manuscript online: 21 OCT 2015 03:34AM EST | DOI: 10.1002/hep.28306

  77. Hepatobiliary Malignancies

    1. Novel population-based study finding higher than reported hepatocellular carcinoma incidence suggests an updated approach is needed

      Thai Hong, Paul Gow, Michael Fink, Anouk Dev, Stuart Roberts, Amanda Nicoll, John Lubel, Ian Kronborg, Niranjan Arachchi, Marno Ryan, William Kemp, Virginia Knight, Helen Farrugia, Vicky Thursfield, Paul Desmond, Alexander Thompson and Sally Bell

      Accepted manuscript online: 5 OCT 2015 03:55AM EST | DOI: 10.1002/hep.28267

  78. Correspondence

    1. Reply

      Lily Dara and Neil Kaplowitz

      Accepted manuscript online: 29 SEP 2015 11:10AM EST | DOI: 10.1002/hep.28262

    2. Reply to the Letter Entitled “Severe Hepatotoxicity Associated with Asunaprevir and Daclatasvir in Chronic Hepatitis C”

      Yohei Fujii, Yoshihito Uchida and Satoshi Mochida

      Accepted manuscript online: 6 AUG 2015 06:40PM EST | DOI: 10.1002/hep.28114

  79. Viral Hepatitis

    1. Retracted: HLA-A2-/HLA-DR1-transgeneic H-2 class I-/class II-knockout mouse is an ideal animal model for study of chronic HBV infection

      Ding-Qiang Chen, Ling Yang, Jie Zhou, Liwei Lu, Yu-Chun Lone, Kwok-Yung Yuen and Bo-Jian Zheng

      Accepted manuscript online: 23 AUG 2010 11:36AM EST | DOI: 10.1002/hep.23932

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