Hepatology

Cover image for Vol. 59 Issue 5

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: Michael H. Nathanson

Impact Factor: 12.003

ISI Journal Citation Reports © Ranking: 2012: 2/74 (Gastroenterology & Hepatology)

Online ISSN: 1527-3350

Associated Title(s): Clinical Liver Disease, Liver Transplantation

  1. Liver Injury and Regeneration

    1. IL-20 and IL-20R1 antibodies protect against liver fibrosis

      Yi-Shu Chiu, Chi-Chen Wei, Yih-Jyh Lin, Yu-Hsiang Hsu and Ming-Shi Chang

      Accepted manuscript online: 25 APR 2014 03:29AM EST | DOI: 10.1002/hep.27189

  2. Viral Hepatitis

    1. Human OX40 tunes the function of regulatory T cells in tumor and non-tumor areas of HCV-infected liver tissue

      Silvia Piconese, Eleonora Timperi, Ilenia Pacella, Valeria Schinzari, Claudio Tripodo, Massimo Rossi, Nicola Guglielmo, Gianluca Mennini, Gian Luca Grazi, Simona Di Filippo, Stefania Brozzetti, Katia Fazzi, Guido Antonelli, Maria Antonietta Lozzi, Massimo Sanchez and Vincenzo Barnaba

      Accepted manuscript online: 23 APR 2014 04:20AM EST | DOI: 10.1002/hep.27188

  3. Comments from the Editors

  4. Hepatology Elsewhere

    1. cGAS, innate immune responses and viral hepatitis

      Eloi R. Verrier, Michaela U. Gack and Thomas F. Baumert

      Accepted manuscript online: 22 APR 2014 02:16AM EST | DOI: 10.1002/hep.27187

  5. Viral Hepatitis

    1. The multifaceted functions of ribavirin: Antiviral, immunomodulator or both?

      Mario U. Mondelli

      Accepted manuscript online: 22 APR 2014 02:15AM EST | DOI: 10.1002/hep.27186

  6. Correspondence

    1. Prognostic Impact of Telomere Maintenance Gene Polymorphisms in Hepatocellular Carcinoma Patients-Some Issues Needed to be Clarified

      Fei Liu, Wen-Tao Wang, Yong-Gang Wei and Bo Li

      Accepted manuscript online: 20 APR 2014 09:16PM EST | DOI: 10.1002/hep.27184

    2. Reply

      Neung Hwa Park, Seok Won Jung, Eun-Soon Shin and Young-Hwa Chung

      Accepted manuscript online: 20 APR 2014 09:02PM EST | DOI: 10.1002/hep.27183

  7. Viral Hepatitis

    1. Ursodeoxycholic acid in primary sclerosing cholangitis: If withdrawal is bad, then administration is good (right?)

      James H. Tabibian and Keith D. Lindor

      Accepted manuscript online: 19 APR 2014 12:40AM EST | DOI: 10.1002/hep.27180

  8. Steatohepatitis and Metabolic Liver Disease

    1. Utility and appropriateness of the FLIP algorithm and SAF score in the evaluation of biopsies of nonalcoholic fatty liver disease

      Pierre Bedossa, Alastair D. Burt, Annette S.H. Gouw, Carolin Lackner, Peter Schirmacher, Luigi Terracciano, D. Tiniakos, J. Brain, Yvonne Bury, Daniela Cabibi, Frederic Charlotte, Ezio David, Luisa Losi, Matteo Montani, María Jesús Pareja, Dominique Wendum, Fritz Wrba, Marianne Ziol and Vlad Ratziu

      Accepted manuscript online: 19 APR 2014 12:40AM EST | DOI: 10.1002/hep.27173

  9. Correspondence

    1. Re: Unresectable solitary HCC not amenable to RFA: Multicenter radiology-pathology correlation and survival of radiation segmentectomy

      Riad Salem, Michael Vouche, Ali Habib, Edward Kim, Kent T Sato, Ryan Hickey and Robert Lewandowski

      Accepted manuscript online: 19 APR 2014 12:40AM EST | DOI: 10.1002/hep.27179

  10. Viral Hepatitis

    1. Vitamin D deficiency and liver cancer: More than just an epidemiological association?

      Massimo Colombo and Angelo Sangiovanni

      Accepted manuscript online: 19 APR 2014 12:35AM EST | DOI: 10.1002/hep.27178

  11. Correspondence

    1. Association between response to peginterferon/ribavirin therapy and ribavirin levels

      Chia-Yen Dai, Ming-Lung Yu and Wan-Long Chuang

      Accepted manuscript online: 19 APR 2014 12:35AM EST | DOI: 10.1002/hep.27181

  12. Viral Hepatitis

    1. Persistent viremia in HIV-hepatitis B co-infected patients undergoing long-term tenofovir: virological and clinical implications

      Anders Boyd, Joël Gozlan, Sarah Maylin, Constance Delaugerre, Gilles Peytavin, Pierre-Marie Girard, Fabien Zoulim and Karine Lacombe

      Accepted manuscript online: 19 APR 2014 12:19AM EST | DOI: 10.1002/hep.27182

  13. Hepatobiliary Malignancies

    1. Hepatocyte nuclear factor 4α-nuclear factor-κB feedback circuit modulates liver cancer progression

      Bei-Fang Ning, Jin Ding, Jiao Liu, Chuan Yin, Wen-Ping Xu, Wen-Ming Cong, Qing Zhang, Fei Chen, Tao Han, Xing Deng, Pei-Qin Wang, Cai-Feng Jiang, Jun-Ping Zhang, Xin Zhang, Hong-Yang Wang and Wei-Fen Xie

      Accepted manuscript online: 18 APR 2014 11:27AM EST | DOI: 10.1002/hep.27177

  14. Correspondence

    1. Is segmental trans-arterial yttrium 90 radiation a curative option for solitary hepatocellular carcinoma ≤5cm?

      Olivier Seror, Jean-Charles Nault, Pierre Nahon, Gisele N'Kontchou and Jean-Claude Trinchet

      Accepted manuscript online: 18 APR 2014 10:45AM EST | DOI: 10.1002/hep.27174

  15. Steatohepatitis and Metabolic Liver Disease

    1. Saturated free fatty acids induce cholangiocyte lipoapoptosis

      Sathish Kumar Natarajan, Sally A. Ingham, Ashley M. Mohr, Cody J. Wehrkamp, Anuttoma Ray, Sohini Roy, Sophie C Cazanave, Mary Anne Phillippi and Justin L. Mott

      Accepted manuscript online: 18 APR 2014 10:44AM EST | DOI: 10.1002/hep.27175

  16. Correspondence

    1. Letter to the editor

      Manish Thapar and Herbert L Bonkovsky

      Accepted manuscript online: 18 APR 2014 10:33AM EST | DOI: 10.1002/hep.27176

  17. Viral Hepatitis

    1. Obesity and Hepatocellular Carcinoma: Hype and Reality

      Hashem B. El-Serag and Fasiha Kanwal

      Accepted manuscript online: 18 APR 2014 01:58AM EST | DOI: 10.1002/hep.27172

  18. Liver Biology and Pathobiology

    1. Transcriptional dynamics of bile salt export pump during pregnancy: Mechanisms and implications in intrahepatic cholestasis of pregnancy

      Xiulong Song, Alexander Vasilenko, Yuan Chen, Leila Valanejad, Ruchi Verma, Bingfang Yan and Ruitang Deng

      Accepted manuscript online: 11 APR 2014 10:55PM EST | DOI: 10.1002/hep.27171

  19. Autoimmune, Cholestatic and Biliary Disease

    1. Phosphorylation of ABCB4 impacts its function: Insights from disease-causing mutations

      Julien Gautherot, Danièle Delautier, Marie-Anne Maubert, Tounsia Aït-Slimane, Gérard Bolbach, Jean-Louis Delaunay, Anne-Marie Durand-Schneider, Delphine Firrincieli, Véronique Barbu, Nicolas Chignard, Chantal Housset, Michèle Maurice and Thomas Falguières

      Accepted manuscript online: 10 APR 2014 10:22PM EST | DOI: 10.1002/hep.27170

  20. Correspondence

    1. Reply

      An Verrijken, Sven Francque, Ilse Mertens and Luc Van Gaal

      Accepted manuscript online: 10 APR 2014 10:22PM EST | DOI: 10.1002/hep.27167

  21. Liver Injury and Regeneration

    1. Thymic Stromal Lymphopoietin and Interleukin-4 Mediate the Pathogenesis of Halothane-Induced Liver Injury in Mice

      William R. Proctor, Mala Chakraborty, Aaron M. Fullerton, Midhun C. Korrapati, Pauline M. Ryan, Kenrick Semple, Jeffrey C. Morrison, Julia D. Berkson, Lynette S. Chea, Qian Yang, Albert P. Li, Rosanne Spolski, Erin E. West, Yrina Rochman, Warren J. Leonard, Mohammed Bourdi and Lance R. Pohl

      Accepted manuscript online: 10 APR 2014 10:22PM EST | DOI: 10.1002/hep.27169

  22. Correspondence

    1. Helicobacter pylori Might Contribute to Nonalcoholic Fatty Liver Disease–related Cardiovascular Events by Releasing Pro-thrombotic and Pro-inflammatory Factors

      Jannis Kountouras, Stergios A. Polyzos, Christos Zavos, Georgia Deretzi, Constantinos Kountouras, Elizabeth Vardaka, Panagiotis Katsinelos, Elena Tsiaousi, Nikolaos Grigoriadis, Iordanis Romiopoulos, Dimitrios Tzilves and Evangelia Giartza-Taxidou

      Accepted manuscript online: 10 APR 2014 10:20PM EST | DOI: 10.1002/hep.27168

    2. Association between female sex, IL28B genotype but also DQB1*0301allele and the outcome of acute hepatitis C virus infection

      Laurent Alric, Delphine Bonnet and Marylise Fort

      Accepted manuscript online: 8 APR 2014 11:40PM EST | DOI: 10.1002/hep.27164

  23. Liver Injury and Regeneration

    1. Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells

      Noushin Dianat, Hélène Dubois-Pot-Schneider, Clara Steichen, Christophe Desterke, Philippe Leclerc, Aurélien Raveux, Laurent Combettes, Anne Weber, Anne Corlu and Anne Dubart-Kupperschmitt

      Accepted manuscript online: 8 APR 2014 11:39PM EST | DOI: 10.1002/hep.27165

  24. Hepatobiliary Malignancies

    1. Index-based dietary patterns and risk of incident hepatocellular carcinoma and mortality from chronic liver disease in a prospective study

      Wen-Qing Li, Yikyung Park, Katherine A. McGlynn, Albert R. Hollenbeck, Philip R. Taylor, Alisa M. Goldstein and Neal D. Freedman

      Accepted manuscript online: 8 APR 2014 11:37PM EST | DOI: 10.1002/hep.27160

  25. Correspondence

    1. The genetics of spontaneous clearance of hepatitis C virus infection: A complex topic with much to learn

      Jason Grebely, Gregory J. Dore, Arthur Y. Kim, Andrew Lloyd, Naglaa H. Shoukry, Maria Prins and Kimberly Page

      Accepted manuscript online: 8 APR 2014 11:30PM EST | DOI: 10.1002/hep.27163

  26. Viral Hepatitis

    1. Patient-reported outcomes in chronic hepatitis C patients with cirrhosis treated with sofosbuvir-containing regimens

      Zobair M. Younossi, Maria Stepanova, Fatema Nader, Ira M. Jacobson, Ed Gane, David Nelson, Eric Lawitz and Sharon L. Hunt

      Accepted manuscript online: 8 APR 2014 03:36AM EST | DOI: 10.1002/hep.27161

    2. Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of the bile acid metabolism

      Nicola Oehler, Tassilo Volz, Oliver D. Bhadra, Janine Kah, Lena Allweiss, Katja Giersch, Jeanette Bierwolf, Kristoffer Riecken, Jörg M. Pollok, Ansgar W. Lohse, Boris Fehse, Joerg Petersen, Stephan Urban, Marc Lütgehetmann, Joerg Heeren and Maura Dandri

      Accepted manuscript online: 8 APR 2014 03:13AM EST | DOI: 10.1002/hep.27159

  27. Liver Injury and Regeneration

    1. Caveolin-1 is essential for protecting against binge drinking-induced liver damage through inhibiting reactive nitrogen species

      Lei Gao, Yingchun Zhou, Weichao Zhong, Xiaohua Zhao, Chun Chen, Xingmiao Chen, Yong Gu, Jianping Chen, Zhiping Lv and Jiangang Shen

      Accepted manuscript online: 8 APR 2014 03:12AM EST | DOI: 10.1002/hep.27162

  28. Original Articles

    1. Reversal of hepatocyte senescence after continuous in vivo cell proliferation

      Min-Jun Wang, Fei Chen, Jian-Xiu Li, Chang-Cheng Liu, Hai-Bin Zhang, Yong Xia, Bing Yu, Pu You, Dao Xiang, Lian Lu, Hao Yao, Uyunbilig Borjigin, Guang-Shun Yang, Kirk J. Wangensteen, Zhi-Ying He, Xin Wang and Yi-Ping Hu

      Accepted manuscript online: 7 APR 2014 09:40AM EST | DOI: 10.1002/hep.27094

  29. Correction

    1. Antiretroviral therapy, Interferon Sensitivity, and Virologic Set Point in HIV-Hepatitis C Virus Co-infected Patients

      A Balagopal, AJ Kandathil, YH Higgins, J Wood, J Richer, J Quinn, L Eldred, Z Li, SC Ray, MS Sulkowski and DL Thomas

      Accepted manuscript online: 5 APR 2014 03:58AM EST | DOI: 10.1002/hep.27158

  30. Hepatology Elsewhere

    1. Integrins, myofibroblasts, and organ fibrosis

      Michel Fausther and Jonathan Dranoff

      Accepted manuscript online: 2 APR 2014 09:52AM EST | DOI: 10.1002/hep.27155

  31. Liver Injury and Regeneration

    1. The spectrum of statin hepatotoxicity: Experience of the drug induced liver injury network

      Mark W. Russo, Jay H. Hoofnagle, Jiezhun Gu, Robert J Fontana, Huiman Barnhart, David E Kleiner, Naga Chalasani and Herbert L Bonkovsky

      Accepted manuscript online: 2 APR 2014 09:50AM EST | DOI: 10.1002/hep.27157

  32. Liver Failure, Cirrhosis and Portal Hypertension

    1. Continuous outpatient terlipressin infusion for hepatorenal syndrome as a bridge to successful liver transplantation

      Marcus Robertson, Avik Majumdar, Kent Garrett, Greg Rumler, Paul Gow and Adam Testro

      Accepted manuscript online: 31 MAR 2014 01:46AM EST | DOI: 10.1002/hep.27154

  33. Clinical Perspectives in Hepatology

    1. A chronic disease management model for chronic liver failure

      Alan J Wigg, Mohamed A Chinnaratha, Rachel Wundke and Michael L. Volk

      Accepted manuscript online: 28 MAR 2014 03:43AM EST | DOI: 10.1002/hep.27152

  34. Steatohepatitis and Metabolic Liver Disease

    1. Inhibition of miR-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia

      Raymond Ng, Heng Wu, Hong Xiao, Xin Chen, Holger Willenbring, Clifford J. Steer and Guisheng Song

      Accepted manuscript online: 28 MAR 2014 03:42AM EST | DOI: 10.1002/hep.27153

  35. Viral Hepatitis

    1. Cost analysis of sofosbuvir/ribavirin versus sofosbuvir/simeprevir for genotype 1 HCV in interferon ineligible/intolerant individuals

      Liesl M. Hagan, Mark S. Sulkowski and Raymond F. Schinazi

      Accepted manuscript online: 28 MAR 2014 12:31AM EST | DOI: 10.1002/hep.27151

    2. Engineering Liver

      Linda G. Griffith, Alan Wells and Donna Beer Stolz

      Accepted manuscript online: 26 MAR 2014 04:13AM EST | DOI: 10.1002/hep.27150

  36. Liver Biology and Pathobiology

    1. Microvilli as markers of disordered apical-membrane trafficking and assembly: Bowel and liver

      Richard J Thompson and AS Knisely

      Accepted manuscript online: 26 MAR 2014 04:10AM EST | DOI: 10.1002/hep.27148

  37. Liver Injury and Regeneration

    1. The role of platelets in systemic tissue protection after RIPC

      Patrick Starlinger and Thomas Gruenberger

      Accepted manuscript online: 26 MAR 2014 04:10AM EST | DOI: 10.1002/hep.27146

  38. Steatohepatitis and Metabolic Liver Disease

    1. Hypercaloric diets with increased meal frequency, but not meal size, increase intrahepatic triglycerides: A randomized controlled trial

      Karin E Koopman, Matthan WA Caan, Aart J Nederveen, Anouk Pels, Mariette T Ackermans, Eric Fliers, Susanne E la Fleur and Mireille J Serlie

      Accepted manuscript online: 26 MAR 2014 03:33AM EST | DOI: 10.1002/hep.27149

  39. Liver Biology and Pathobiology

    1. FGF21: a new liver safeguard

      Marica Cariello and Antonio Moschetta

      Accepted manuscript online: 26 MAR 2014 03:33AM EST | DOI: 10.1002/hep.27147

  40. Viral Hepatitis

    1. Ending Vertical Transmission of Hepatitis B: The Third Trimester Intervention

      Monika Sarkar and Norah A. Terrault

      Accepted manuscript online: 26 MAR 2014 03:30AM EST | DOI: 10.1002/hep.27145

  41. Liver Biology and Pathobiology

    1. Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice

      Hyon-Seung Yi, Young-Sun Lee, Jin-Seok Byun, Wonhyo Seo, Jong-Min Jeong, Ogyi Park, Gregg Duester, Takeshi Haseba, Sun Chang Kim, Keun-Gyu Park, Bin Gao and Won-Il Jeong

      Accepted manuscript online: 26 MAR 2014 03:11AM EST | DOI: 10.1002/hep.27137

  42. Viral Hepatitis

    1. Truncated CXCL10 is associated with failure to achieve spontaneous clearance of acute hepatitis C infection

      Antonio Riva, Melissa Laird, Armanda Casrouge, Arvydas Ambrozaitis, Roger Williams, Nikolai V Naoumov, Matthew L Albert and Shilpa Chokshi

      Accepted manuscript online: 26 MAR 2014 02:59AM EST | DOI: 10.1002/hep.27139

  43. Liver Failure, Cirrhosis and Portal Hypertension

    1. Bioactive compound reveals a novel function for ribosomal protein S5 in hepatic stellate cell activation and hepatic fibrosis

      Wei-Heng Xu, Hong-Gang Hu, Yuan Tian, Shao-Zhan Wang, Jie Li, Jian-Zhong Li, Xing Deng, Hui Qian, Lei Qiu, Zhen-Lin Hu, Qiu-Ye Wu, Yi-Feng Chai, Cheng Guo, Wei-Fen Xie and Jun-Ping Zhang

      Accepted manuscript online: 26 MAR 2014 02:56AM EST | DOI: 10.1002/hep.27138

  44. Steatohepatitis and Metabolic Liver Disease

    1. You have full text access to this OnlineOpen article
      Endogenous annexin A1 IS a novel protective determinant in nonalcoholic steatohepatitis (NASH)

      Irene Locatelli, Salvatore Sutti, Aastha Jindal, Marco Vacchiano, Cristina Bozzola, Chris Reutelingsperger, Dennis Kusters, Stefania Bena, Maurizio Parola, Claudia Paternostro, Elisabetta Bugianesi, Simon McArthur, Emanuele Albano and Mauro Perretti

      Accepted manuscript online: 25 MAR 2014 04:30AM EST | DOI: 10.1002/hep.27141

  45. Liver Injury and Regeneration

    1. Suppression of autophagy during liver regeneration impairs energy charge and hepatocyte senescence in mice

      Takeo Toshima, Ken Shirabe, Takasuke Fukuhara, Toru Ikegami, Tomoharu Yoshizumi, Yuji Soejima, Tetsuo Ikeda, Shinji Okano and Yoshihiko Maehara

      Accepted manuscript online: 25 MAR 2014 04:22AM EST | DOI: 10.1002/hep.27140

  46. Correspondence

    1. The innate immune system of the liver: May it explain the stronger viral clearance in female sex?

      Ricardo Marcos and Carla Gomes

      Accepted manuscript online: 25 MAR 2014 04:21AM EST | DOI: 10.1002/hep.27142

  47. Liver Injury and Regeneration

    1. You have full text access to this OnlineOpen article
      Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration

      Freimut Schliess, Stefan Hoehme, Sebastian G. Henkel, Ahmed Ghallab, Dominik Driesch, Jan Böttger, Reinhard Guthke, Michael Pfaff, Jan G. Hengstler, Rolf Gebhardt, Dieter Häussinger, Dirk Drasdo and Sebastian Zellmer

      Accepted manuscript online: 19 MAR 2014 02:29AM EST | DOI: 10.1002/hep.27136

  48. Viral Hepatitis

    1. Is the Adiponectin-AMPK-mitochondrial axis involved in progression of non-alcoholic fatty liver disease?

      Srinivasan Dasarathy

      Accepted manuscript online: 18 MAR 2014 07:28AM EST | DOI: 10.1002/hep.27134

  49. Hepatology Elsewhere

    1. Cost-effectiveness analysis of liver resection versus transplantation for early hepatocellular carcinoma within the Milan criteria

      K.C. Lim, V.W. Wang, F.J. Siddiqui, L.M. Shi, S.Y.E. Chan, H.C. Oh, S.B. Tan and P.K.H. Chow

      Accepted manuscript online: 18 MAR 2014 05:25AM EST | DOI: 10.1002/hep.27135

  50. Hepatobiliary Malignancies

    1. BRAF V600E mutations in bile duct adenomas

      Anaïs Pujals, Giuliana Amaddeo, Claire Castain, Paulette Bioulac-Sage, Philippe Compagnon, Jessica Zucman-Rossi, Daniel Azoulay, Karen Leroy, Elie Serge Zafrani and Julien Calderaro

      Accepted manuscript online: 16 MAR 2014 11:58PM EST | DOI: 10.1002/hep.27133

  51. Clinical Observations in Hepatology

    1. Diagnosis of Sinusoidal Obstruction Syndrome by Positron Emission Tomography/Computed Tomography: report of 2 cases treated by defibrotide

      Mathieu Gauthé, Laurence Bozec and Pierre Bedossa

      Accepted manuscript online: 16 MAR 2014 11:44PM EST | DOI: 10.1002/hep.27132

  52. Review

    1. You have full text access to this OnlineOpen article
      Epigenetics in Liver Disease

      Derek A Mann

      Accepted manuscript online: 16 MAR 2014 09:46PM EST | DOI: 10.1002/hep.27131

  53. Correspondence

  54. Liver Injury and Regeneration

    1. Activation of invariant natural killer T cells impedes liver regeneration via both IFN-γ- and IL-4-dependent mechanisms

      Shi Yin, Hua Wang, Adeline Bertola, Dechun Feng, Ming-jiang Xu, Yan Wang and Bin Gao

      Accepted manuscript online: 13 MAR 2014 04:50AM EST | DOI: 10.1002/hep.27128

  55. Viral Hepatitis

    1. Soluble CD163, a macrophage activation marker, is independently associated with fibrosis in patients with chronic viral hepatitis B and C

      Konstantin Kazankov, Francisco Barrera, Holger Jon Møller, Bo Martin Bibby, Hendrik Vilstrup, Jacob George and Henning Grønbæk

      Accepted manuscript online: 13 MAR 2014 04:45AM EST | DOI: 10.1002/hep.27129

  56. Correspondence

    1. Regarding: ‘Obeticholic acid, a FXR agonist, improves portal hypertension by two distinct pathways in cirrhotic rats'

      Rajeshwar Mookerjee, Gautam Mehta and Rajiv Jalan

      Accepted manuscript online: 13 MAR 2014 04:34AM EST | DOI: 10.1002/hep.27123

    2. Is there a straightforward relationship between hepatitis C virus infection and diabetes?

      Pan Zhao, Zhenman Wei and Wanshu Liu

      Accepted manuscript online: 13 MAR 2014 04:32AM EST | DOI: 10.1002/hep.27126

    3. Obeticholic acid in portal hypertension : Ready for clinical prime-time or do we need more experimental data ?

      Len Verbeke, Jonel Trebicka and Wim Laleman

      Accepted manuscript online: 13 MAR 2014 04:31AM EST | DOI: 10.1002/hep.27125

  57. Liver Failure, Cirrhosis and Portal Hypertension

    1. A Quick Diagnosis of Hepatic Encephalopathy: Fact or Fiction?

      Sara Montagnese, Sami Schiff and Piero Amodio

      Accepted manuscript online: 13 MAR 2014 04:29AM EST | DOI: 10.1002/hep.27127

  58. Autoimmune, Cholestatic and Biliary Disease

    1. E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network

      Yuxia Zhang, Ningyi Xu, Jun Xu, Bo Kong, Bryan Copple, Grace L. Guo and Li Wang

      Accepted manuscript online: 11 MAR 2014 10:40PM EST | DOI: 10.1002/hep.27121

  59. Correspondence

    1. Rebleeding Prophylaxis Improved Outcomes in Patients With Hepatocelluar Carcinoma: Is it feasible in all patients?

      Ping-Hsien Chen and Ming-Chih Hou

      Accepted manuscript online: 11 MAR 2014 10:35PM EST | DOI: 10.1002/hep.27122

    2. Reply

      Cristina Ripoll, Joan Genescà and Jaime Bosch

      Accepted manuscript online: 11 MAR 2014 10:33PM EST | DOI: 10.1002/hep.27119

  60. Viral Hepatitis

    1. Progress in hepatitis b: A 30-year journey through three continents

      Anna Suk-Fong Lok

      Accepted manuscript online: 11 MAR 2014 10:32PM EST | DOI: 10.1002/hep.27120

  61. Hepatobiliary Malignancies

    1. Identification of miR-214 as a negative regulator of colorectal cancer liver metastasis via regulation of FGFR1 expression

      Dong-liang Chen, Zhi-qiang Wang, Zhao-lei Zeng, Wen-jing Wu, Dong-sheng Zhang, Hui-yan Luo, Feng Wang, Miao-zhen Qiu, De-shen Wang, Chao Ren, Feng-hua Wang, Lucia J Chiao, Helene Pelicano, Peng Huang, Yu-hong Li and Rui-hua Xu

      Accepted manuscript online: 11 MAR 2014 04:59AM EST | DOI: 10.1002/hep.27118

  62. Liver Biology and Pathobiology

    1. AT1 receptor-mediated Janus-kinase-2 activation induces liver fibrosis

      Michaela Granzow, Robert Schierwagen, Sabine Klein, Benita Kowallick, Sebastian Huss, Markus Linhart, Irela Gretchen Reza Mazar, Jan Görtzen, Annabelle Vogt, Frank Alexander Schildberg, Maria A. Gonzalez-Carmona, Alexandra Wojtalla, Benjamin Krämer, Jacob Nattermann, Sören Volker Siegmund, Nikos Werner, Dieter O. Fürst, Wim Laleman, Percy Knolle, Vijay H. Shah, Tilman Sauerbruch and Jonel Trebicka

      Accepted manuscript online: 11 MAR 2014 04:58AM EST | DOI: 10.1002/hep.27117

  63. Hepatology Elsewhere

    1. Sinusoidal Endothelial Cells Direct Traffic at the Intersection of Regeneration and Fibrosis

      Robert C. Huebert and Vijay H. Shah

      Accepted manuscript online: 11 MAR 2014 04:37AM EST | DOI: 10.1002/hep.27116

  64. Clinical Observations in Hepatology

    1. Hepatocellular carcinoma and nodular regenerative hyperplasia after chemotherapy for metastatic colorectal carcinoma

      Julien Calderaro, Daniel Azoulay and Elie-Serge Zafrani

      Accepted manuscript online: 7 MAR 2014 01:15AM EST | DOI: 10.1002/hep.27115

  65. Viral Hepatitis

    1. C5a/C5aR pathway is essential for the pathogenesis of murine viral fulminant hepatitis via potentiating Fgl2/fibroleukin expression

      Gui-lian Xu, Jian Chen, Fei Yang, Gui-qing Li, Li-xin Zheng and Yu-zhang Wu

      Accepted manuscript online: 7 MAR 2014 01:14AM EST | DOI: 10.1002/hep.27114

  66. Comments from the Editors

    1. La mort de la lipogenèse: RNF20 lashes ubiquitin to SREBP-1c

      Simon W. Beaven

      Accepted manuscript online: 7 MAR 2014 01:08AM EST | DOI: 10.1002/hep.27112

  67. Correspondence

    1. Reply

      Jamuna Karkhanis, Elizabeth C. Verna, Matthew S. Chang, R. Todd Stravitz, Michael L. Schilsky, William M. Lee and Robert S. Brown

      Accepted manuscript online: 5 MAR 2014 04:07AM EST | DOI: 10.1002/hep.27110

    2. Historical, present and future significance of corticosteroid in the treatment of acute liver failure

      Keiichi Fujiwara, Shin Yasui and Osamu Yokosuka

      Accepted manuscript online: 4 MAR 2014 03:51AM EST | DOI: 10.1002/hep.27111

    3. Itpa Variants are Associated with Reduced Relapse Rate but not with Early Virological Responses Following Hcv Genotype 2/3 Therapy

      Martin Lagging, Karolina Rembeck, Jesper Waldenström, Staffan Nilsson, Kristina Nyström, Anna Martner, Magnus Lindh, Gunnar Norkrans, Johan Westin, Court Pedersen, Martti Färkkilä, Nina Langeland, Mads Rauning Buhl, Kristine Mørch, Peer Brehm Christensen and Kristoffer Hellstrand

      Accepted manuscript online: 4 MAR 2014 03:43AM EST | DOI: 10.1002/hep.27108

    4. Variants of the inosine triphosphate pyrophosphatase gene and relapse risk following treatment for HCV genotype 2/3

      Chia-Yen Dai, Wan-Long Chuang and Ming-Lung Yu

      Accepted manuscript online: 4 MAR 2014 03:40AM EST | DOI: 10.1002/hep.27109

    5. FDA bridging analyses confirmed in clinical trial

      Poonam Mishra, Jeffry Florian and Jeffrey Murray

      Accepted manuscript online: 2 MAR 2014 09:39PM EST | DOI: 10.1002/hep.27107

  68. Liver Injury and Regeneration

    1. PolySia-NCAM modulates the formation of ductular reactions in liver injury

      Atsunori Tsuchiya, Wei-Yu Lu, Birgit Weinhold, Luke Boulter, Benjamin M Stutchfield, Michael J Williams, Rachel V Guest, Sarah E Minnis-Lyons, Alison C MacKinnon, David Schwarzer, Takafumi Ichida, Minoru Nomoto, Yutaka Aoyagi, Rita Gerardy-Schahn and Stuart J Forbes

      Accepted manuscript online: 28 FEB 2014 04:07AM EST | DOI: 10.1002/hep.27099

  69. Viral Hepatitis

    1. Late HDV RNA relapse after peginterferon alfa-based therapy of chronic hepatitis delta

      Benjamin Heidrich, Cihan Yurdaydın, Gökhan Kabaçam, Boris A. Ratsch, Kalliopi Zachou, Birgit Bremer, George N. Dalekos, Andreas Erhardt, Fehmi Tabak, Kendal Yalcin, Selim Gürel, Stefan Zeuzem, Markus Cornberg, C.-Thomas Bock, Michael P. Manns, Heiner Wedemeyer and for the HIDIT-1 Study group

      Accepted manuscript online: 28 FEB 2014 03:44AM EST | DOI: 10.1002/hep.27102

  70. Correspondence

    1. Benefits of Albumin Infusion in Patients Undergoing Large-Volume Paracentesis

      Mauro Bernardi, Paolo Caraceni, Roberta J. Navickis and Mahlon M. Wilkes

      Accepted manuscript online: 28 FEB 2014 03:42AM EST | DOI: 10.1002/hep.27105

  71. Liver Biology and Pathobiology

    1. Treatment of phenylketonuria using minicircle-based naked-DNA gene transfer to murine liver

      Hiu Man Viecelli, Richard P. Harbottle, Suet Ping Wong, Andrea Schlegel, Marinee K. Chuah, Thierry VandenDriessche, Cary O. Harding and Beat Thöny

      Accepted manuscript online: 28 FEB 2014 03:41AM EST | DOI: 10.1002/hep.27104

  72. Correspondence

    1. Reply

      Teresa Antonia Santantonio, Massimo Fasano and Evangelista Sagnelli

      Accepted manuscript online: 28 FEB 2014 03:40AM EST | DOI: 10.1002/hep.27100

  73. Viral Hepatitis

    1. A computerized physician order entry-based system to prevent HBV reactivation in patients treated with biologic agents. The PRESCRIB Project

      Blanca Sampedro, Cándido Hernández-López, José Ramón Ferrandiz, Aitziber Illaro, Emilio Fábrega, Antonio Cuadrado, Paula Iruzubieta, Susana Menéndez, Joaquín Cabezas and Javier Crespo

      Accepted manuscript online: 28 FEB 2014 03:38AM EST | DOI: 10.1002/hep.27103

  74. Correspondence

    1. A 24-week peg-Interferon alpha-2b versus a 12-week peg-Interferon alpha-2b alone or with ribavirin for patients with acute hepatitis C

      Chia-Yen Dai, Wan-Long Chuang and Ming-Lung Yu

      Accepted manuscript online: 28 FEB 2014 03:38AM EST | DOI: 10.1002/hep.27096

  75. Steatohepatitis and Metabolic Liver Disease

    1. Prevalence and natural history of histologically proven chronic liver disease in a longitudinal cohort of patients with type 1 diabetes

      David John Harman, Philip Kaye, Rebecca Harris, Ayako Suzuki, Anastasios Gazis and Guruprasad Padur Aithal

      Accepted manuscript online: 28 FEB 2014 03:36AM EST | DOI: 10.1002/hep.27098

  76. Correspondence

    1. Trial Sequence Meta-Analysis Can Reject False Positive Result Calculated from Conventional Meta-Analysis

      Ren-Pin Chen, Chao Chen, Jie-Yu Yu, Xie-Lin Huang, Meng-tao Zhou and Zhi-Ming Huang

      Accepted manuscript online: 28 FEB 2014 03:36AM EST | DOI: 10.1002/hep.27106

    2. The Influence of Menopause on the Development of Hepatic Fibrosis in Non-obese Women with Nonalcoholic Fatty Liver Disease

      Masato Yoneda, Emmanuel Thomas, Yoshio Sumida, Yuichiro Eguchi and Eugene R Schiff

      Accepted manuscript online: 28 FEB 2014 03:35AM EST | DOI: 10.1002/hep.27097

  77. Research Articles

    1. HCV Genotype 3 is Associated with an Increased Risk of Cirrhosis and Hepatocellular Cancer in a National Sample of U.S. Veterans with HCV

      Fasiha Kanwal, Jennifer R. Kramer, Jawad Ilyas, Zhigang Duan and Hashem B. El-Serag

      Accepted manuscript online: 24 FEB 2014 09:44PM EST | DOI: 10.1002/hep.27095

  78. Original Articles

    1. Gd-EOB-DTPA-enhanced magnetic resonance imaging and alpha-fetoprotein predict prognosis of early-stage hepatocellular carcinoma

      Taro Yamashita, Azusa Kitao, Osamu Matsui, Takehiro Hayashi, Kouki Nio, Mitsumasa Kondo, Naoki Ohno, Toshiaki Miyati, Hikari Okada, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Yasuni Nakanuma, Hiroyuki Takamura, Tetsuo Ohta, Yasunari Nakamoto, Masakazu Yamamoto, Tadatoshi Takayama, Shigeki Arii, Xin Wei Wang and Shuichi Kaneko

      Accepted manuscript online: 23 FEB 2014 03:29AM EST | DOI: 10.1002/hep.27093

  79. Editorial

    1. NRF2, not always friendly but perhaps misunderstood

      George K. Michalopoulos

      Accepted manuscript online: 23 FEB 2014 03:28AM EST | DOI: 10.1002/hep.27090

  80. Original Articles

    1. Systemic protection through remote ischemic preconditioning is spread via platelet-dependent signaling

      Christian E. Oberkofler, Perparim Limani, Jae-Hwi Jang, Andreas Rickenbacher, Kuno Lehmann, Dimitri A. Raptis, Yinghua Tian, Kamile Grabliauskaite, Rok Humar, Rolf Graf, Bostjan Humar and Pierre-Alain Clavien

      Accepted manuscript online: 23 FEB 2014 03:27AM EST | DOI: 10.1002/hep.27089

    2. Progression of Autoimmune Hepatitis is Mediated by IL-18-Producing Dendritic Cells and Hepatic CXCL9 Expression in Mice

      Aki Ikeda, Nobuhiro Aoki, Masahiro Kido, Satoru Iwamoto, Hisayo Nishiura, Ryutaro Maruoka, Tsutomu Chiba and Norihiko Watanabe

      Accepted manuscript online: 23 FEB 2014 03:24AM EST | DOI: 10.1002/hep.27087

    3. Ribavirin improves the IFN-γ response of natural killer cells to IFN-based therapy of hepatitis C virus infection

      Jens M. Werner, Elisavet Serti, Xenia Chepa-Lotrea, Jonathan Stoltzfus, Golo Ahlenstiel, Mazen Noureddin, Jordan J. Feld, T. Jake Liang, Yaron Rotman and Barbara Rehermann

      Accepted manuscript online: 23 FEB 2014 03:18AM EST | DOI: 10.1002/hep.27092

  81. Review

    1. Role of protein kinase C isoforms in bile formation and cholestasis

      M. Sawkat Anwer

      Accepted manuscript online: 22 FEB 2014 09:51PM EST | DOI: 10.1002/hep.27088

  82. Original

    1. Clonal tracing of Sox9+ liver progenitors in oval cell injury

      Branden D. Tarlow, Milton J. Finegold and Markus Grompe

      Accepted manuscript online: 22 FEB 2014 09:45PM EST | DOI: 10.1002/hep.27084

    2. You have full text access to this OnlineOpen article
      Conjugated bile acids promote cholangiocarcinoma cell invasive growth via activation of sphingosine 1-phosphate receptor 2

      Runping Liu, Renping Zhao, Xiqiao Zhou, Xiuyin Liang, Deanna J.W. Campbell, Xiaoxuan Zhang, Luyong Zhang, Ruihua Shi, Guangji Wang, William M. Pandak, Alphonse E. Sirica, Phillip B. Hylemon and Huiping Zhou

      Accepted manuscript online: 22 FEB 2014 09:35PM EST | DOI: 10.1002/hep.27085

  83. Special Articles

    1. Liver transplantation in the management of porphyria

      Ashwani K. Singal, Charles Parker, Christine Bowden, Manish Thapar, Lawrence Liu and Brendan M. McGuire

      Accepted manuscript online: 22 FEB 2014 09:31PM EST | DOI: 10.1002/hep.27086

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