Hepatology

Cover image for Vol. 60 Issue 6

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: Michael H. Nathanson

Impact Factor: 11.19

ISI Journal Citation Reports © Ranking: 2013: 3/75 (Gastroenterology & Hepatology)

Online ISSN: 1527-3350

Associated Title(s): Clinical Liver Disease, Liver Transplantation

VIEW

  1. 1 - 100
  2. 101 - 192
  1. Hepatology Elsewhere

    1. Is petoxifylline still an option in severe alcoholic hepatitis?

      Juan Caballeria

      Accepted manuscript online: 12 DEC 2014 07:20PM EST | DOI: 10.1002/hep.27657

  2. Hepatobiliary Malignancies

    1. High liver fibrosis index FIB-4 highly predictive of hepatocellular carcinoma in chronic hepatitis B carriers

      Beomseok Suh, Sehhoon Park, Dong Wook Shin, Jae Moon Yun, Hyung-Kook Yang, Su Jong Yu, Cheong-Il Shin, Jin-Soo Kim, Eunmi Ahn, Hyejin Lee, Jin Ho Park and BeLong Cho

      Accepted manuscript online: 12 DEC 2014 07:18PM EST | DOI: 10.1002/hep.27654

    2. Vps4A functions as a tumor suppressor by regulating the secretion and uptake of exosomal microRNAs in human hepatoma cells

      Jin-xing Wei, Li-hong Lv, Yun-le Wan, Yang Cao, Guo-lin Li, Hao-ming Lin, Rui Zhou, Chang-zhen Shang, Jun Cao, Hai He, Qing-fang Han, Pei-qing Liu, Gang Zhou and Jun Min

      Accepted manuscript online: 12 DEC 2014 07:16PM EST | DOI: 10.1002/hep.27660

  3. Correspondence

    1. Reply: HEP-14-2331 TM6SF2 as a genetic risk factor for fibrosis

      Silvia Sookoian and Carlos J. Pirola

      Accepted manuscript online: 12 DEC 2014 07:16PM EST | DOI: 10.1002/hep.27655

  4. Viral Hepatitis

    1. Determining the fate of hepatic cells by lineage tracing: Facts and pitfalls

      Frédéric P. Lemaigre

      Accepted manuscript online: 12 DEC 2014 07:16PM EST | DOI: 10.1002/hep.27659

    2. Beyond scar formation: Portal myofibroblast-mediated angiogenesis in the fibrotic liver

      Michel Fausther and Jonathan A. Dranoff

      Accepted manuscript online: 12 DEC 2014 07:15PM EST | DOI: 10.1002/hep.27653

  5. Hepatobiliary Malignancies

    1. Activation of the TGFβ/SMAD transcriptional pathway underlies a novel tumor promoting role of sulfatase1 in hepatocellular carcinoma

      Renumathy Dhanasekaran, Ikuo Nakamura, Chunling Hu, Gang Chen, Abdul M. Oseini, Elif Sezin Seven, Alexander G Miamen, Catherine D Moser, Wei Zhou, Toin H. vanKuppevelt, Jan vanDeursen, Taofic Mounajjed, Martin E. Fernandez-Zapico and Lewis R. Roberts

      Accepted manuscript online: 12 DEC 2014 07:10PM EST | DOI: 10.1002/hep.27658

  6. Correspondence

    1. TM6SF2 as a genetic risk factor for fibrosis

      Ann K. Daly, Christopher P. Day, Yang-Lin Liu and Quentin M. Anstee

      Accepted manuscript online: 12 DEC 2014 07:06PM EST | DOI: 10.1002/hep.27656

  7. Liver Injury and Regeneration

    1. FGF2lmw attenuates hepatic fibrosis via epigenetic downregulation of Delta-like1

      Ruo-Lang Pan, Li-Xin Xiang, Ping Wang, Xiao-Yuan Liu, Li Nie, Wendong Huang and Jian-Zhong Shao

      Accepted manuscript online: 11 DEC 2014 06:33AM EST | DOI: 10.1002/hep.27649

  8. Viral Hepatitis

    1. Universal infant immunization and occult hepatitis B virus infection in children and adolescents: a population-based study

      Hong-Yuan Hsu, Mei-Hwei Chang, Yen-Hsuan Ni, Cheng-Lun Chiang, Jia-Feng Wu and Huey-Ling Chen

      Accepted manuscript online: 11 DEC 2014 06:32AM EST | DOI: 10.1002/hep.27650

  9. Liver Biology and Pathobiology

    1. Potential of human Induced Pluripotent Stem Cells in studies of liver disease

      Fotios Sampaziotis, Charis-Patricia Segeritz and Ludovic Vallier

      Accepted manuscript online: 11 DEC 2014 06:31AM EST | DOI: 10.1002/hep.27651

  10. Correspondence

    1. Reply

      Yeon Seok Seo, Chang Ho Jung, Tae Hyung Kim, Sun Young Yim and Soon Ho Um

      Accepted manuscript online: 6 DEC 2014 11:20AM EST | DOI: 10.1002/hep.27646

  11. Steatohepatitis and Metabolic Liver Disease

    1. Ezetimibe for the treatment of nonalcoholic steatohepatitis: Assessment by novel MRI and MRE in a randomized trial (MOZART Trial)

      Rohit Loomba, Claude B. Sirlin, Brandon Ang, Ricki Bettencourt, Rashmi Jain, Joanie Salotti, Linda Soaft, Jonathan Hooker, Yuko Kono, Archana Bhatt, Laura Hernandez, Phirum Nguyen, Mazen Noureddin, William Haufe, Catherine Hooker, Meng Yin, Richard Ehman, Grace Lin, Mark Valasek, David Brenner, Lisa Richards and San Diego Integrated Research Consortium (SINC)

      Accepted manuscript online: 6 DEC 2014 11:20AM EST | DOI: 10.1002/hep.27647

  12. Liver Biology and Pathobiology

    1. Liver X receptors balance lipid stores in hepatic stellate cells via Rab18, a retinoid responsive lipid droplet protein

      Fiona O'Mahony, Kevin Wroblewski, Sheila M. O'Byrne, Hongfeng Jiang, Kara Clerkin, Jihane Benhammou, William S. Blaner and Simon W. Beaven

      Accepted manuscript online: 6 DEC 2014 11:11AM EST | DOI: 10.1002/hep.27645

  13. Liver Failure, Cirrhosis and Portal Hypertension

  14. Viral Hepatitis

    1. You have full text access to this OnlineOpen article
      Minimum target prices for production of direct acting antivirals and associated diagnostics to combat Hepatitis C Virus

      Nikolien van de Ven, Joe Fortunak, Bryony Simmons, Nathan Ford, Graham Cooke, Saye Khoo and Andrew Hill

      Accepted manuscript online: 6 DEC 2014 01:04AM EST | DOI: 10.1002/hep.27641

  15. Steatohepatitis and Metabolic Liver Disease

    1. PNPLA3 rs738409 and TM6SF2 rs58542926 gene variants affect renal disease and function in NAFLD

      Giovanni Musso, Maurizio Cassader and Roberto Gambino

      Accepted manuscript online: 6 DEC 2014 01:04AM EST | DOI: 10.1002/hep.27643

  16. Correspondence

    1. PNPLA3 I148M genetic variant and kidney disease

      Stefano Romeo, Paola Dongiovanni, Salvatore Petta, Jussi Pihalajamaki and Luca Valenti

      Accepted manuscript online: 6 DEC 2014 01:03AM EST | DOI: 10.1002/hep.27642

  17. Liver Failure, Cirrhosis and Portal Hypertension

    1. Prostaglandin E2-mediated immunosuppression and the role of albumin as its modulator

      Won Hyeok Choe and Soon Koo Baik

      Accepted manuscript online: 6 DEC 2014 01:03AM EST | DOI: 10.1002/hep.27644

  18. Viral Hepatitis

    1. TNFR1 signaling in ALD – a gut reaction?

      Shirish Barve, Irina A. Kirpich and C.J. McClain

      Accepted manuscript online: 6 DEC 2014 01:03AM EST | DOI: 10.1002/hep.27640

    2. A sensor at the lipid - protein interface: Lipid peroxidation controls hepatitis C virus replication

      David Paul and Ralf Bartenschlager

      Accepted manuscript online: 5 DEC 2014 03:45AM EST | DOI: 10.1002/hep.27637

  19. Liver Failure, Cirrhosis and Portal Hypertension

    1. Dysregulated iron homeostasis is strongly associated with multi-organ failure and early mortality in acute-on-chronic liver failure

      Jaswinder Singh Maras, Rakhi Maiwall, H. C. Harsha, Sukanta Das, Shabir Hussain, Chandan Kumar, Chhagan Bihari, Archana Rastogi, Manoj Kumar, Nirupama trehanpati, Shvetank Sharma, Akhilesh Pandey and Shiv Kumar Sarin

      Accepted manuscript online: 5 DEC 2014 03:43AM EST | DOI: 10.1002/hep.27636

  20. Correspondence

    1. Reply

      Krasimira Aleksandrova and Tobias Pischon

      Accepted manuscript online: 5 DEC 2014 03:42AM EST | DOI: 10.1002/hep.27638

  21. Autoimmune, Cholestatic and Biliary Disease

    1. Autoimmune hepatitis in a murine APS-1 model is directed against multiple autoantigens

      Matthias Hardtke-Wolenski, Richard Taubert, Fatih Noyan, Maren Sievers, Janine Dywicki, Jerome Schlue, Christine S. Falk, Brita Ardesjö Lundgren, Hamish S. Scott, Andreas Pich, Mark S. Anderson, Michael P. Manns and Elmar Jaeckel

      Accepted manuscript online: 5 DEC 2014 03:42AM EST | DOI: 10.1002/hep.27639

  22. Correspondence

    1. Difference of Budd-Chiari syndrome between West and China

      Jian-Gao Fan and Fu-Sheng Wang

      Accepted manuscript online: 5 DEC 2014 02:48AM EST | DOI: 10.1002/hep.27627

    2. Difference of Budd-Chiari syndrome between West and China

      Xingshun Qi, Xiaozhong Guo and Daiming Fan

      Accepted manuscript online: 5 DEC 2014 02:48AM EST | DOI: 10.1002/hep.27628

  23. Liver Injury and Regeneration

    1. Resolution of liver fibrosis requires myeloid cell-driven sinusoidal angiogenesis

      Chahrazade Kantari-Mimoun, Magali Castells, Ralph Klose, Anna-Katharina Meinecke, Ursula J. Lemberger, Pierre-Emmanuel Rautou, Hélène Pinot-Roussel, Cécile Badoual, Katrin Schrödter, Christoph H. Österreicher, Joachim Fandrey and Christian Stockmann

      Accepted manuscript online: 5 DEC 2014 02:48AM EST | DOI: 10.1002/hep.27635

    2. Inhibition of type I NKT cells by retinoids or following sulfatide-mediated activation of type II NKT cells attenuates alcoholic liver disease

      Igor Maricic, Huiming Sheng, Idania Marrero, Ehikiro Seki, Tatiana Kisseleva, Som Chaturvedi, Natasha Molle, K., Stephanie Mathews, Bin Gao and Vipin Kumar

      Accepted manuscript online: 5 DEC 2014 02:48AM EST | DOI: 10.1002/hep.27632

  24. Viral Hepatitis

    1. Significant reduction in end-stage liver diseases burden through national viral hepatitis therapy program in Taiwan

      Chun-Ju Chiang, Ya-Wen Yang, Jin-De Chen, San-Lin You, Hwai-I Yang, Mei-Hsuan Lee, Mei-Shu Lai and Chien-Jen Chen

      Accepted manuscript online: 5 DEC 2014 02:44AM EST | DOI: 10.1002/hep.27630

  25. Comments from the Editors

    1. A multi-journal partnership to highlight joint first-authors of manuscripts

      M. Bishr Omary, Michael B. Wallace, Emad M. El-Omar, Rajiv Jalan and Michael H. Nathanson

      Accepted manuscript online: 5 DEC 2014 02:43AM EST | DOI: 10.1002/hep.27631

  26. Liver Failure, Cirrhosis and Portal Hypertension

    1. Interleukin-22 and IL-22 binding protein (IL-22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections

      Mathieu Sertorio, Xunya Hou, Rodrigo F Carmo, Hélia Dessein, Sandrine Cabantous, Mohammed Abdelwahed, Audrey Romano, Fernanda Albuquerque, Luydson Vasconcelos, Theomira Carmo, Jun Li, Arthur Varoquaux, Violaine Arnaud, Pablo Oliveira, Anas Hamdoun, Hongbin He, Suzan Adbelmaboud, Adil Mergani, Jie Zhou, Ahmed Monis, Leila Beltrao Pereira, Philippe Halfon, Marc Bourlière, Raymundo Parana, Mitermayer dos Reis, David Gonnelli, Patricia Moura, Nasr Eldin Elwali, Laurent Argiro, Yuesheng Li and Alain Dessein

      Accepted manuscript online: 5 DEC 2014 02:39AM EST | DOI: 10.1002/hep.27629

  27. Hepatobiliary Malignancies

    1. Issue in statistical strategy in case-control study

      Xiang-Yong Li, Min-Jun Bai, Lin-Jun Chen, Jian-Liang Xu, Zhi-Huan Lin, Xing Li and Yan-Fang Xing

      Accepted manuscript online: 5 DEC 2014 02:39AM EST | DOI: 10.1002/hep.27633

  28. Correspondence

    1. Screening for occult hepatitis C virus infection, does it need special attention?

      Mohammad Saeid Rezaee-Zavareh, Mahdi Ramezani Binabaj and Seyed Moayed Alavian

      Accepted manuscript online: 5 DEC 2014 02:28AM EST | DOI: 10.1002/hep.27626

  29. Viral Hepatitis

    1. HCV induced reduction in miR-181a impairs CD4+ T cell responses via over-expression of DUSP6

      Guang Y. Li, Yun Zhou, Ruo S. Ying, Lei Shi, Yong Q. Cheng, Jun P. Ren, Jeddidiah W.D. Griffin, Zhan S. Jia, Chuan F. Li, Jonathan P. Moorman and Zhi Q. Yao

      Accepted manuscript online: 5 DEC 2014 02:27AM EST | DOI: 10.1002/hep.27634

    2. Long-term effect of HCV eradication in patients with mixed cryoglobulinemia: A prospective, controlled, open-label, cohort study

      Laura Gragnani, Elisa Fognani, Alessia Piluso, Barbara Boldrini, Teresa Urraro, Alessio Fabbrizzi, Cristina Stasi, Jessica Ranieri, Monica Monti, Umberto Arena, Claudio Iannacone, Giacomo Laffi, Anna Linda Zignego and for the MaSVE study group.

      Accepted manuscript online: 27 NOV 2014 04:27AM EST | DOI: 10.1002/hep.27623

  30. Comments from the Editors

    1. Introducing the AASLD president: Gyongyi Szabo

      Craig McClain

      Accepted manuscript online: 27 NOV 2014 04:25AM EST | DOI: 10.1002/hep.27625

  31. Hepatobiliary Malignancies

    1. When good TGF-β Turns bad in hepatocellular carcinoma: Axl takes the stage

      Diego F. Calvisi

      Accepted manuscript online: 27 NOV 2014 04:07AM EST | DOI: 10.1002/hep.27624

  32. Correspondence

    1. Serum alkaline phosphatase levels accurately reflect cholestasis in mice

      Elisabeth Krones, Wolfgang Erwa, Michael Trauner and Peter Fickert

      Accepted manuscript online: 25 NOV 2014 11:32PM EST | DOI: 10.1002/hep.27622

  33. Liver Biology and Pathobiology

    1. Enhancing the functional maturity of iPSC-derived human hepatocytes via controlled presentation of cell-cell interactions in vitro

      Dustin R. Berger, Brenton R. Ware, Matthew D. Davidson, Samuel R. Allsup and Salman R. Khetani

      Accepted manuscript online: 25 NOV 2014 03:53AM EST | DOI: 10.1002/hep.27621

  34. Steatohepatitis and Metabolic Liver Disease

    1. Perilipin 5: From fatty liver to hepatic lipodystrophy?

      Julia Szendroedi and Michael Roden

      Accepted manuscript online: 25 NOV 2014 03:52AM EST | DOI: 10.1002/hep.27618

  35. Liver Biology and Pathobiology

    1. Analysis of aberrant pre-messenger RNA splicing due to mutations in ATP8B1 and efficient in vitro rescue by adapted U1 small nuclear RNA

      Wendy L. van der Woerd, Johanna Mulder, Franco Pagani, Ulrich Beuers, Roderick H.J. Houwen and Stan F.J. van de Graaf

      Accepted manuscript online: 25 NOV 2014 03:51AM EST | DOI: 10.1002/hep.27620

  36. Liver Injury and Regeneration

    1. Gadd34 regulates liver regeneration in hepatic steatosis

      Yuka Inaba, Tomoko Furutani, Kumi Kimura, Hitoshi Watanabe, Sanae Haga, Yoshiaki Kido, Michihiro Matsumoto, Yasuhiko Yamamoto, Kenichi Harada, Shuichi Kaneko, Seiichi Oyadomari, Michitaka Ozaki, Masato Kasuga and Hiroshi Inoue

      Accepted manuscript online: 25 NOV 2014 03:51AM EST | DOI: 10.1002/hep.27619

  37. Viral Hepatitis

    1. Prevention of hepatitis C virus infection and spread in human liver chimeric mice by an anti-CD81 monoclonal antibody

      Changhua Ji, Yang Liu, Chandra Pamulapati, Sandhya Bohini, Georg Fertig, Michael Schraeml, Werner Rubas, Michael Brandt, Stefan Ries, Han Ma and Klaus Klumpp

      Accepted manuscript online: 22 NOV 2014 03:31AM EST | DOI: 10.1002/hep.27603

  38. Clinical Observations in Hepatology

    1. Cholestatic hepatitis from prolonged kratom use: A case report

      Christina Dorman, Dr. Mark Wong and Dr. Aazib Khan

      Accepted manuscript online: 22 NOV 2014 03:30AM EST | DOI: 10.1002/hep.27612

  39. Liver Injury and Regeneration

    1. Modeling idiosyncrasy: A novel animal model of drug-induced liver injury

      Gwilym J Webb and David H Adams

      Accepted manuscript online: 22 NOV 2014 12:01AM EST | DOI: 10.1002/hep.27617

  40. Steatohepatitis and Metabolic Liver Disease

  41. Correspondence

    1. Reply

      Jürgen J. Wenzel and Wolfgang Jilg

      Accepted manuscript online: 21 NOV 2014 10:44AM EST | DOI: 10.1002/hep.27613

  42. Viral Hepatitis

    1. A monocytic detour to replicate patient-derived hepatitis C virus in hepatoma cells and its use for phenotypic analyses

      Laurent Chatel-Chaix and Ralf Bartenschlager

      Accepted manuscript online: 21 NOV 2014 10:42AM EST | DOI: 10.1002/hep.27614

  43. Hepatobiliary Malignancies

    1. “Percutaneous ablative treatments of hepatocellular carcinoma “

      Gian Ludovico Rapaccini

      Accepted manuscript online: 21 NOV 2014 10:40AM EST | DOI: 10.1002/hep.27615

  44. Viral Hepatitis

    1. No artifact, hepatitis E is emerging

      prof.dr. Hans L. Zaaijer

      Accepted manuscript online: 21 NOV 2014 10:36AM EST | DOI: 10.1002/hep.27611

    2. The p.Ser267Phe variant in SLC10A1 is associated with resistance to chronic hepatitis B

      Liang Peng, Qiang Zhao, Qibin Li, Miaoxin Li, Caixia Li, Tingting Xu, Xiangyi Jing, Xiang Zhu, Ye Wang, Fucheng Li, Ruihong Liu, Cheng Zhong, Qihao Pan, Binghui Zeng, Qijun Liao, Bin Hu, Zhao-xia Hu, Yang-su Huang, Pak Sham, Jinsong Liu, Shuhua Xu, Jun Wang, Zhi-liang Gao and Yiming Wang

      Accepted manuscript online: 21 NOV 2014 10:35AM EST | DOI: 10.1002/hep.27608

    3. Cooperation between MYC and companion 8q genes in hepatocarcinogenesis

      Scott Powers

      Accepted manuscript online: 21 NOV 2014 10:35AM EST | DOI: 10.1002/hep.27605

  45. Hepatobiliary Malignancies

    1. Development of risk scoring system for stratifying population for hepatocellular-carcinoma screening

      Yi-Chun Hung, Chih-Lin Lin, Chun-Jen Liu, Hung Hung, Shi-Ming Lin, Shou-Dong Lee, Pei-Jer Chen, Shu-Chun Chuang and Ming-Whei Yu

      Accepted manuscript online: 21 NOV 2014 10:34AM EST | DOI: 10.1002/hep.27610

  46. Viral Hepatitis

    1. HBsAg genetic elements critical for immune escape correlate with HBV-reactivation upon immunosuppression

      Romina Salpini, Luna Colagrossi, Maria Concetta Bellocchi, Matteo Surdo, Christina Becker, Claudia Alteri, Marianna Aragri, Alessandra Ricciardi, Daniele Armenia, Michela Pollicita, Fabiola Di Santo, Luca Carioti, Yoram Louzoun, Claudio Maria Mastroianni, Miriam Lichtner, Maurizio Paoloni, Mariarosaria Esposito, Chiara D'Amore, Aldo Marrone, Massimo Marignani, Cesare Sarrecchia, Loredana Sarmati, Massimo Andreoni, Mario Angelico, Jens Verhejen, Carlo-Federico Perno and Valentina Svicher

      Accepted manuscript online: 21 NOV 2014 10:34AM EST | DOI: 10.1002/hep.27604

    2. Recent FDA warnings on hepatitis B reactivation with immune-suppressing and anti-cancer drugs: Just the tip of the iceberg?

      Adrian M. Di Bisceglie, Anna S. Lok, Paul Martin, Norah Terrault, Robert P. Perrillo and Jay H. Hoofnagle

      Accepted manuscript online: 21 NOV 2014 03:00AM EST | DOI: 10.1002/hep.27609

  47. Liver Biology and Pathobiology

    1. Cre-ativity in the liver: transgenic approaches to targeting hepatic non-parenchymal cells

      Stephen N. Greenhalgh, Kylie P. Conroy and Neil C. Henderson

      Accepted manuscript online: 21 NOV 2014 02:10AM EST | DOI: 10.1002/hep.27606

  48. Hepatology Elsewhere

    1. TGF-β-induced long non-coding RNA promotes liver cancer metastasis via RNA-RNA cross-talk

      Tingting Sun and Nathalie Wong

      Accepted manuscript online: 7 NOV 2014 05:43AM EST | DOI: 10.1002/hep.27599

  49. Correspondence

    1. The case for cost-effectively treating cryoglobulinemic vasculitis with interferon-free anti-hepatitis C virus therapy

      Marcella Visentini, Stefania Colantuono, Guido Granata, Adriano de Santis, Massimo Fiorilli and Milvia Casato

      Accepted manuscript online: 7 NOV 2014 02:14AM EST | DOI: 10.1002/hep.27600

  50. Viral Hepatitis

    1. Should patients with hepatitis C GT2/3 infection who are slow responders to PEG-interferon/ribavirin have treatment duration extended?

      C Silva, E Ianna, T Jones and J.S. Davis

      Accepted manuscript online: 7 NOV 2014 02:07AM EST | DOI: 10.1002/hep.27601

  51. Clinical Perspectives in Hepatology

    1. The clinical course of cirrhosis: The importance of multi-state models and competing risks analysis

      Peter Jepsen, Hendrik Vilstrup and Per Kragh Andersen

      Accepted manuscript online: 5 NOV 2014 08:20AM EST | DOI: 10.1002/hep.27598

  52. Liver Biology and Pathobiology

    1. Autosis occurs in the liver of patients with severe anorexia nervosa

      Marouane Kheloufi, Chantal M Boulanger, Patrice Codogno and Pierre-Emmanuel Rautou

      Accepted manuscript online: 5 NOV 2014 08:09AM EST | DOI: 10.1002/hep.27597

  53. Hepatology Elsewhere

    1. You have full text access to this OnlineOpen article
      Estimation of hepatitis C virus infections resulting from vertical transmission in Egypt

      Lenka Benova, Susanne F. Awad, F. DeWolfe Miller and Laith J. Abu-Raddad

      Accepted manuscript online: 4 NOV 2014 07:32AM EST | DOI: 10.1002/hep.27596

  54. Liver Biology and Pathobiology

    1. Conjugated Bile Acid Activated S1P Receptor 2 Is a Key Regulator of Sphingosine Kinase 2 and Hepatic Gene Expression

      Masayuki Nagahashi, Kazuaki Takabe, Runping Liu, Kesong Peng, Xiang Wang, Yun Wang, Nitai C. Hait, Xuan Wang, Jeremy C. Allegood, Akimitsu Yamada, Tomoyoshi Aoyagi, Jie Liang, William M. Pandak, Sarah Spiegel, Phillip B. Hylemon and Huiping Zhou

      Accepted manuscript online: 1 NOV 2014 03:22AM EST | DOI: 10.1002/hep.27592

  55. Hepatobiliary Malignancies

    1. You have full text access to this OnlineOpen article
      C/EBPalpha predicts poorer prognosis and prevents energy starvation–induced cell death in hepatocellular carcinoma

      Guo-Dong Lu, Yang Huey Ang, Jing Zhou, Jegadeesan Tamilarasi, Benedict Yan, Yaw Chyn Lim, Supriya Srivastava, Manuel Salto-Tellez, Kam M. Hui, Han-Ming Shen, Long N. Nguyen, Bryan C. Tan, David L. Silver and Shing Chuan Hooi

      Accepted manuscript online: 1 NOV 2014 03:20AM EST | DOI: 10.1002/hep.27593

  56. Correspondence

    1. A call to action: The need for hepatology-focused educational interventions in internal medicine residency training

      Adam E. Mikolajczyk, Andrew A. Aronsohn, John F. McConville, Donald M. Jensen and Jeanne M. Farnan

      Accepted manuscript online: 1 NOV 2014 02:58AM EST | DOI: 10.1002/hep.27591

    2. Effect of interferon-alfa therapy on hepatitis D virus

      Ashish Goyal and John M. Murray

      Accepted manuscript online: 31 OCT 2014 07:03PM EST | DOI: 10.1002/hep.27595

    3. Reply

      Jeremie Guedj, Laetitia Canini, Scott Cotler and Harel Dahari

      Accepted manuscript online: 31 OCT 2014 07:03PM EST | DOI: 10.1002/hep.27594

  57. Viral Hepatitis

    1. Peg-interferon therapy of chronic hepatitis D; in need of revision

      Mario Rizzetto and Antonina Smedile

      Accepted manuscript online: 28 OCT 2014 04:37AM EST | DOI: 10.1002/hep.27585

    2. The continuum of hepatitis C testing and care

      Kendra Viner, Danica Kuncio, E. Claire Newbern and Caroline C. Johnson

      Accepted manuscript online: 28 OCT 2014 04:37AM EST | DOI: 10.1002/hep.27584

    3. Soft and hard endpoints in acute variceal bleeding

      Juan G Abraldes and Puneeta Tandon

      Accepted manuscript online: 28 OCT 2014 04:37AM EST | DOI: 10.1002/hep.27583

    4. Adding peginterferon to entecavir for HBeAg-positive chronic hepatitis B: A multicentre randomized trial (ARES study)

      Willem Pieter Brouwer, Qing Xie, Milan Johan Sonneveld, Ningping Zhang, Qing Zhang, Fehmi Tabak, Anca Streinu, Ji-Yao Wang, Ramazan Idilman, Hendrik Reesink, Mircea Diculescu, Krzysztof Simon, Mihai Voiculescu, Meral Akdogan, Wlodzimierz Mazur, Jurrien Reijnders, Elke Verhey, Bettina Hansen, Harry L.A. Janssen and for the ARES study group

      Accepted manuscript online: 28 OCT 2014 04:27AM EST | DOI: 10.1002/hep.27586

    5. Variations in serum sphingolipid levels associate with liver fibrosis progression and poor treatment outcome in HCV but not HBV infection

      Georgios Grammatikos, Nerea Ferreiros, Dimitra Bon, Stephanie Schwalm, Julia Dietz, Caterina Berkowski, Daniel Fitting, Eva Herrmann, Stefan Zeuzem, Christoph Sarrazin and Josef Pfeilschifter

      Accepted manuscript online: 28 OCT 2014 04:26AM EST | DOI: 10.1002/hep.27587

  58. Correspondence

    1. Letter to the Editor

      Nora V. Bergasa

      Accepted manuscript online: 25 OCT 2014 01:52AM EST | DOI: 10.1002/hep.27582

  59. Autoimmune, Cholestatic and Biliary Disease

    1. The role of autotaxin and lysophosphatidic acid in pruritus of cholestasis

      Ronald Oude Elferink, Ruth Bolier, Andreas E. Kremer and Ulrich Beuers

      Accepted manuscript online: 25 OCT 2014 01:51AM EST | DOI: 10.1002/hep.27579

  60. Viral Hepatitis

    1. Sofosbuvir modulates the intimate relationship between hepatitis C virus and lipids

      Manuel Romero-Gómez and Ángela Rojas

      Accepted manuscript online: 25 OCT 2014 01:51AM EST | DOI: 10.1002/hep.27581

  61. Hepatobiliary Malignancies

    1. Retinoic acid-related orphan receptor alpha reprograms glucose metabolism in glutamine-deficient hepatoma cells

      Jun-Kyu Byun, Yeon-Kyung Choi, Yu Na Kang, Byoung Kuk Jang, Koo Jeong Kang, Yong Hyun Jeon, Ho-Won Lee, Jae-Han Jeon, Seung-Hoi Koo, Won-Il Jeong, Robert A Harris, In-Kyu Lee and Keun-Gyu Park

      Accepted manuscript online: 25 OCT 2014 01:49AM EST | DOI: 10.1002/hep.27577

  62. Liver Biology and Pathobiology

    1. Crucial roles of MLL3 and MLL4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis

      Dae-Hwan Kim, Jennifer Chiyeon Rhee, Sujeong Yeo, Rongkun Shen, Soo-Kyung Lee, Jae W. Lee and Seunghee Lee

      Accepted manuscript online: 25 OCT 2014 01:49AM EST | DOI: 10.1002/hep.27578

  63. Correspondence

    1. Reply

      Patrick Starlinger, Mickael Lesurtel, Christine Brostjan, Pierre-Alain Clavien and Thomas Gruenberger

      Accepted manuscript online: 20 OCT 2014 11:35PM EST | DOI: 10.1002/hep.27574

  64. Liver Biology and Pathobiology

    1. Systems biological analyses reveal the HCV-specific regulation of hematopoietic development

      Victoria M. Velazquez, Luke S. Uebelhoer, Manoj Thapa, Chris Ibegbu, Cynthia Courtney, Steven E. Bosinger, Joseph F. Magliocca, Andrew B. Adams, Allan D. Kirk, Stuart J. Knechtle, Daniel Kalman, Mehul Suthar and Arash Grakoui

      Accepted manuscript online: 20 OCT 2014 11:33PM EST | DOI: 10.1002/hep.27575

  65. Steatohepatitis and Metabolic Liver Disease

    1. FSP27β, a novel Fat Specific Protein 27 isoform promoting hepatic steatosis

      Vishwajeet Puri

      Accepted manuscript online: 20 OCT 2014 11:33PM EST | DOI: 10.1002/hep.27573

  66. Liver Failure, Cirrhosis and Portal Hypertension

    1. Predictive value of indocyanine green retention test and ICG-clearance in Child-Pugh class A patients

      Marie-Louise Pind, Søren Møller, Nasrin Faqir and Flemming Bendtsen

      Accepted manuscript online: 20 OCT 2014 04:37AM EST | DOI: 10.1002/hep.27569

  67. Autoimmune, Cholestatic and Biliary Disease

    1. CREMα overexpression impairs function of hepatic myeloid derived suppressor cells and aggravates immune-mediated hepatitis in mice

      Linda Hammerich, Klaudia Theresa Warzecha, Martina Stefkova, Matthias Bartneck, Kim Ohl, Nikolaus Gassler, Tom Luedde, Christian Trautwein, Klaus Tenbrock and Frank Tacke

      Accepted manuscript online: 20 OCT 2014 04:34AM EST | DOI: 10.1002/hep.27571

  68. Correspondence

    1. Serotonin in liver tumor: Friend or foe?

      Qing Pang, Chang Liu, Jing Yao Zhang, Kai Qu, Si Dong Song, Su Shun Liu and Xin Sen Xu

      Accepted manuscript online: 20 OCT 2014 04:32AM EST | DOI: 10.1002/hep.27568

  69. Viral Hepatitis

    1. Development and validation of a ‘capture-fusion’ model to study drug sensitivity of patient-derived hepatitis C

      Morven E Cunningham, Alia Javaid, Jenny Waters, Joseph Davidson-Wright, Joshua L.C. Wong, Meleri Jones and Graham R. Foster

      Accepted manuscript online: 20 OCT 2014 04:01AM EST | DOI: 10.1002/hep.27570

  70. Correspondence

    1. Clinical applications of indocyanine green 15’ retention test (ICG-r15) – beyond Child-Pugh class A

      Andrea Lisotti, Francesco Azzaroli and Giuseppe Mazzella

      Accepted manuscript online: 20 OCT 2014 03:51AM EST | DOI: 10.1002/hep.27572

  71. Rapid Communications

    1. You have full text access to this OnlineOpen article
      Sofosbuvir with peginterferon-ribavirin for 12 weeks in previously treated patients with hepatitis C genotype 2 or 3 and cirrhosis

      Eric Lawitz, Fred Poordad, Diana M. Brainard, Robert H. Hyland, Di An, Hadas Dvory-Sobol, William T. Symonds, John G. McHutchison and Fernando E. Membreno

      Accepted manuscript online: 16 OCT 2014 11:20AM EST | DOI: 10.1002/hep.27567

  72. Autoimmune, Cholestatic and Biliary Disease

    1. Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium

      Ryo Hatano, Kaori Akiyama, Atsushi Tamura, Shigekuni Hosogi, Yoshinori Marunaka, Michael J Caplan, Yoshiyuki Ueno, Sachiko Tsukita and Shinji Asano

      Accepted manuscript online: 13 OCT 2014 11:03AM EST | DOI: 10.1002/hep.27565

  73. Hepatobiliary Malignancies

    1. Differential effects of targeting Notch receptors in a mouse model of liver cancer

      Erik G. Huntzicker, Kathy Hötzel, Lisa Choy, Li Che, Jed Ross, Gregoire Pau, Neeraj Sharma, Christian W. Siebel, Xin Chen and Dorothy M. French

      Accepted manuscript online: 13 OCT 2014 10:47AM EST | DOI: 10.1002/hep.27566

    2. Assessing a MicroRNA panel in diagnosing early cholangiocarcinoma

      Tetsuji Fujita

      Accepted manuscript online: 12 OCT 2014 02:59AM EST | DOI: 10.1002/hep.27561

  74. Steatohepatitis and Metabolic Liver Disease

    1. Responses to: Nitric oxide as a protector from NAFLD

      Qilin Gu and Zongbin Cui

      Accepted manuscript online: 12 OCT 2014 02:59AM EST | DOI: 10.1002/hep.27560

    2. Nitric oxide as a protector from NAFLD

      Manlio Vinciguerra

      Accepted manuscript online: 12 OCT 2014 02:59AM EST | DOI: 10.1002/hep.27562

  75. Correspondence

    1. Refinement of a bile-based extracellular vesicle-derived microRNA panel

      Ling Li and Florin M. Selaru

      Accepted manuscript online: 12 OCT 2014 02:58AM EST | DOI: 10.1002/hep.27564

  76. Liver Failure, Cirrhosis and Portal Hypertension

    1. Biopsy for liver cancer: How to balance research needs with evidence based clinical practice

      Morris Sherman and Jordi Bruix

      Accepted manuscript online: 12 OCT 2014 02:58AM EST | DOI: 10.1002/hep.27563

  77. Hepatobiliary Malignancies

    1. βII-spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and wnt signaling via regulation of wnt inhibitor kallistatin

      Xiuling Zhi, Ling Lin, Shaoxian Yang, Krithika Bhuvaneshwar, Hongkun Wang, Yuriy Gusev, Mi-Hye Lee, Bhaskar Kallakury, Narayan Shivapurkar, Katherine Cahn, Xuefei Tian, John L. Marshall, Stephen W. Byers and Aiwu R. He

      Accepted manuscript online: 12 OCT 2014 02:58AM EST | DOI: 10.1002/hep.27558

  78. Steatohepatitis and Metabolic Liver Disease

    1. Genetic variation in TM6SF2 and the risk of nonalcoholic fatty liver disease and histological disease severity

      Silvia Sookoian, Gustavo O. Castaño, Romina Scian, Pablo Mallardi, Tomas Fernández Gianotti, Adriana L Burgueño, Julio San Martino and Carlos J. Pirola

      Accepted manuscript online: 10 OCT 2014 03:11AM EST | DOI: 10.1002/hep.27556

  79. Correspondence

    1. Differential osteopontin functions: The role of osteopontin isoforms

      Jason D Coombes and Wing-Kin Syn

      Accepted manuscript online: 9 OCT 2014 10:05AM EST | DOI: 10.1002/hep.27555

    2. Reply

      Raul Lazaro, Raymond Wu and Hidekazu Tsukamoto

      Accepted manuscript online: 9 OCT 2014 09:56AM EST | DOI: 10.1002/hep.27554

  80. Hepatobiliary Malignancies

    1. Interleukin-1β/IRAK-1 inflammatory signaling contributes to persistent gankyrin activation during hepatocarcinogenesis

      Bo Su, Tao Luo, Junjie Zhu, Jing Fu, Xiaofang Zhao, Lei Chen, Huilu Zhang, Yibin Ren, Lexing Yu, Xiaojun Yang, Mengchao Wu, Gensheng Feng, Shao Li, Yao Chen and Hongyang Wang

      Accepted manuscript online: 7 OCT 2014 11:09AM EST | DOI: 10.1002/hep.27551

  81. Viral Hepatitis

    1. HIV and liver transplantation: Hepatitis C is the last hurdle

      Peter G. Stock and Norah A. Terrault

      Accepted manuscript online: 7 OCT 2014 10:48AM EST | DOI: 10.1002/hep.27553

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