Hepatology

Cover image for Vol. 61 Issue 3

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: Michael H. Nathanson

Impact Factor: 11.19

ISI Journal Citation Reports © Ranking: 2013: 3/75 (Gastroenterology & Hepatology)

Online ISSN: 1527-3350

Associated Title(s): Clinical Liver Disease, Liver Transplantation

VIEW

  1. 1 - 100
  2. 101 - 178
  1. Research Articles

    1. Liver disease in china: A long way to go

      Tian Yang, Han Zhang, Wan Yee Lau, Feng Shen and Meng-Chao Wu

      Accepted manuscript online: 26 FEB 2015 06:06PM EST | DOI: 10.1002/hep.27769

  2. Viral Hepatitis

    1. Adaptation of the hepatitis B virus core protein to CD8+ T cell selection pressure

      Helenie Kefalakes, Bettina Budeus, Andreas Walker, Christoph Jochum, Gudrun Hilgard, Andreas Heinold, Falko M. Heinemann, Guido Gerken, Daniel Hoffmann and Joerg Timm

      Accepted manuscript online: 26 FEB 2015 06:01PM EST | DOI: 10.1002/hep.27771

    2. Multicenter experience using simeprevir and sofosbuvir with or without ribavirin to treat hepatitis C genotype 1 after liver transplant

      Surakit Pungpapong, Bashar Aqel, Michael Leise, K. Tuesday Werner, Jennifer L. Murphy, Tanisha M. Henry, Kristen Ryland, Amy E. Chervenak, Kymberly D. Watt, Hugo E. Vargas and Andrew P. Keaveny

      Accepted manuscript online: 26 FEB 2015 06:01PM EST | DOI: 10.1002/hep.27770

  3. Correspondence

    1. Reply

      Zhang Zhang, Jian-Gao Fan and Fu-Sheng Wang

      Accepted manuscript online: 26 FEB 2015 06:01PM EST | DOI: 10.1002/hep.27768

  4. Autoimmune, Cholestatic and Biliary Disease

    1. Targeted pharmacotherapy in progressive familial intrahepatic cholestasis type 2: Evidence for improvement of cholestasis with 4-phenylbutyrate

      Emmanuel Gonzales, Brigitte Grosse, Brice Schuller, Anne Davit-Spraul, Filomena Conti, Catherine Guettier, Doris Cassio and Emmanuel Jacquemin

      Accepted manuscript online: 26 FEB 2015 02:08AM EST | DOI: 10.1002/hep.27767

  5. Viral Hepatitis

    1. Risk scores for hepatocellular carcinoma in chronic hepatitis B

      Morris Sherman, Ray W Kim and James Dziura

      Accepted manuscript online: 26 FEB 2015 02:08AM EST | DOI: 10.1002/hep.27765

    2. Towards a more complete understanding of the association between a hepatitis C sustained viral response and cause-specific outcomes

      Hamish A Innes, Scott A McDonald, John F Dillon, Sam Allen, Peter C Hayes, David Goldberg, Peter R Mills, Stephen T Barclay, David Wilks, Heather Valerio, Ray Fox, Diptendu Bhattacharyya, Nicholas Kennedy, Judith Morris, Andrew Fraser, Adrian J Stanley, Peter Bramley and Sharon J Hutchinson

      Accepted manuscript online: 26 FEB 2015 02:08AM EST | DOI: 10.1002/hep.27766

  6. Hepatobiliary Malignancies

    1. A novel vascular pattern promotes metastasis of hepatocellular carcinoma in an EMT-independent manner

      Jian-Hong Fang, Hui-Chao Zhou, Chong Zhang, Li-Ru Shang, Lei Zhang, Jing Xu, Limin Zheng, Yunfei Yuan, Rong-Ping Guo, Wei-Hua Jia, Jing-Ping Yun, Min-Shan Chen, Yaojun Zhang and Shi-Mei Zhuang

      Accepted manuscript online: 24 FEB 2015 06:47PM EST | DOI: 10.1002/hep.27760

  7. Hepatology Elsewhere

    1. Should patients with cirrhosis and variceal hemorrhage receive glucocorticoid therapy?

      Richard Moreau and Emmanuel Weiss

      Accepted manuscript online: 24 FEB 2015 06:47PM EST | DOI: 10.1002/hep.27762

  8. Liver Biology and Pathobiology

    1. Liver fibrosis occurs through dysregulation of MyD88-dependent innate B cell activity

      Manoj Thapa, Raghavan Chinnadurai, Victoria M. Velazquez, Dana Tedesco, Elizabeth Elrod, Jin-Hwan Han, Prachi Sharma, Chris Ibegbu, Andrew Gewirtz, Frank Anania, Bali Pulendran, Mehul S. Suthar and Arash Grakoui

      Accepted manuscript online: 24 FEB 2015 06:47PM EST | DOI: 10.1002/hep.27761

  9. Viral Hepatitis

    1. Drug-induced allergic hepatitis developed in mice when myeloid-derived suppressor cells were depleted prior to halothane treatment

      Mala Chakraborty, Aaron M. Fullerton, Kenrick Semple, Lynette S. Chea, William R. Proctor, Mohammed Bourdi, David E. Kleiner, Xiangbin Zeng, Pauline M. Ryan, Pradeep K. Dagur, Julia D. Berkson, Timothy P. Reilly and Lance R. Pohl

      Accepted manuscript online: 24 FEB 2015 06:46PM EST | DOI: 10.1002/hep.27764

  10. Correspondence

    1. Response to: Putative role of cationic amino acid transporter-3 in murine liver metabolism

      Qilin Gu and Zongbin Cui

      Accepted manuscript online: 24 FEB 2015 06:46PM EST | DOI: 10.1002/hep.27759

  11. Steatohepatitis and Metabolic Liver Disease

    1. Putative role of cationic amino acid transporter-3 in murine liver metabolism

      Ellen I. Closs

      Accepted manuscript online: 24 FEB 2015 06:46PM EST | DOI: 10.1002/hep.27763

  12. Viral Hepatitis

    1. Ledipasvir/sofosbuvir regimens for chronic hepatits c (chc) infection: insights from a work productivity economic model from the United States

      Zobair Younossi, Yushan Jiang, Nathaniel J. Smith, Maria Stepanova and Rachel Beckerman

      Accepted manuscript online: 23 FEB 2015 03:45AM EST | DOI: 10.1002/hep.27757

  13. Correspondence

    1. Reply

      Jude Oben and Anna Mae Diehl

      Accepted manuscript online: 23 FEB 2015 03:45AM EST | DOI: 10.1002/hep.27758

  14. Liver Injury and Regeneration

    1. Inhibition of Wild-type p53-induced phosphatase 1 promotes liver regeneration in mice by direct activation of mTOR

      Lingling Zhang, Leiming Liu, Zhiyong He, Guangbing Li, Junping Liu, Zhangfa Song, Hongchuan Jin, Karl Lenhard Rudolph, Huayu Yang, Yilei Mao, Lianfeng Zhang, Hongbing Zhang, Zhicheng Xiao and Zhenyu Ju

      Accepted manuscript online: 23 FEB 2015 02:32AM EST | DOI: 10.1002/hep.27755

  15. Hepatobiliary Malignancies

    1. Sox12, a direct target of FoxQ1, promotes hepatocellular carcinoma metastasis through up-regulating Twist1 and FGFBP1

      Wenjie Huang, Zhangqian Chen, Xin Shang, Dean Tian, Daowen Wang, Kaichun Wu, Daiming Fan and Limin Xia

      Accepted manuscript online: 23 FEB 2015 02:31AM EST | DOI: 10.1002/hep.27756

  16. Research Articles

    1. Hepatology Highlights

      Jean-François Dufour

      Accepted manuscript online: 20 FEB 2015 05:47PM EST | DOI: 10.1002/hep.27749

  17. Steatohepatitis and Metabolic Liver Disease

    1. Induced pluripotent stem cells model personalized variations in liver disease due to α1-antitrypsin deficiency

      Edgar N. Tafaleng, Souvik Chakraborty, Bing Han, Pamela Hale, Wanquan Wu, Alejandro Soto-Gutierrez, Carol A. Feghali-Bostwick, Andrew A. Wilson, Darrell N. Kotton, Masaki Nagaya, Stephen C. Strom, Jayanta R. Chowdhury, Donna B. Stolz, David H. Perlmutter and Ira J. Fox

      Accepted manuscript online: 18 FEB 2015 01:33AM EST | DOI: 10.1002/hep.27753

  18. Comments from the Editors

    1. John l. Gollan, M.D., Ph.D. March 3, 1942-January 6, 2015

      Michael F. Sorrell

      Accepted manuscript online: 18 FEB 2015 01:06AM EST | DOI: 10.1002/hep.27754

  19. Hepatobiliary Malignancies

    1. Downstaging of Hepatocellular Cancer before Liver Transplant: Long-term Outcome compared to Tumors within Milan Criteria

      Francis Y. Yao, Neil Mehta, Jennifer Flemming, Jennifer Dodge, Bilal Hameed, Oren Fix, Ryutaro Hirose, Nicholas Fidelman, Robert K. Kerlan Jr. and John P. Roberts

      Accepted manuscript online: 18 FEB 2015 12:46AM EST | DOI: 10.1002/hep.27752

  20. Correspondence

    1. Reply

      Kyung Mook Choi and Ho Cheol Hong

      Accepted manuscript online: 17 FEB 2015 11:21PM EST | DOI: 10.1002/hep.27751

  21. Liver Biology and Pathobiology

    1. The significance of non-obstructive sinusoidal dilatation of the liver: Impaired portal perfusion or inflammatory reaction syndrome

      Chiara Marzano, Dominique Cazals-Hatem, Pierre-Emmanuel Rautou and Dominique Valla

      Accepted manuscript online: 13 FEB 2015 02:33AM EST | DOI: 10.1002/hep.27747

  22. Liver Injury and Regeneration

    1. Vector mediated miRNA-21 silencing ameliorates granulomatous liver fibrosis in Schistosoma japonicum infection

      Martina Sombetzki, Micha Loebermann and Emil C. Reisinger

      Accepted manuscript online: 13 FEB 2015 02:28AM EST | DOI: 10.1002/hep.27748

  23. Viral Hepatitis

    1. Improvement of predictive models of risk of disease progression in chronic hepatitis C by incorporating longitudinal data

      Monica A. Konerman, Yiwei Zhang, Ji Zhu, Peter D.R. Higgins, Anna S.F. Lok and Akbar K. Waljee

      Accepted manuscript online: 12 FEB 2015 07:27PM EST | DOI: 10.1002/hep.27750

  24. Correspondence

    1. Targeting FGF19 binding to its receptor system: A novel therapeutic approach for hepatocellular carcinoma

      Farhan Haq and Sung-Min Ahn

      Accepted manuscript online: 11 FEB 2015 06:14AM EST | DOI: 10.1002/hep.27740

  25. Autoimmune, Cholestatic and Biliary Disease

    1. On fibrates and cholestasis: A review

      Nisanne S. Ghonem, David N. Assis and James L. Boyer

      Accepted manuscript online: 11 FEB 2015 06:14AM EST | DOI: 10.1002/hep.27744

  26. Correspondence

    1. Biopsy for liver cancer: How to balance research needs with evidence-based clinical practice

      Boris Blechacz and Lopa Mishra

      Accepted manuscript online: 11 FEB 2015 06:13AM EST | DOI: 10.1002/hep.27746

    2. Targeting FGF19 binding to its receptor system: A novel therapeutic approach for hepatocellular carcinoma

      Nadia Panera, Sara Ceccarelli, Valerio Nobili and Anna Alisi

      Accepted manuscript online: 11 FEB 2015 06:11AM EST | DOI: 10.1002/hep.27741

  27. Viral Hepatitis

    1. Changing hepatitis D virus epidemiology in a hepatitis B virus endemic area with a national vaccination program

      Hsi-Hsun Lin, Susan Shin-Jung Lee, Ming-Lung Yu, Ting-Tsung Chang, Chien-Wei Su, Bor-Shen Hu, Yaw-Sen Chen, Chun-Kai Huang, Chung-Hsu Lai, Jiun-Nong Lin and Jaw-Ching Wu

      Accepted manuscript online: 11 FEB 2015 06:08AM EST | DOI: 10.1002/hep.27742

  28. Liver Failure, Cirrhosis and Portal Hypertension

    1. Complications and competing risks of death in compensated viral cirrhosis (ANRS CO12 CirVir prospective cohort)

      Jean-Claude Trinchet, Valérie Bourcier, Cendrine Chaffaut, Mohand Ait Ahmed, Setty Allam, Patrick Marcellin, Dominique Guyader, Stanislas Pol, Dominique Larrey, Victor De Lédinghen, Denis Ouzan, Fabien Zoulim, Dominique Roulot, Albert Tran, Jean-Pierre Bronowicki, Jean-Pierre Zarski, Odile Goria, Paul Calès, Jean-Marie Péron, Laurent Alric, Marc Bourlière, Philippe Mathurin, Jean-Frédéric Blanc, Armand Abergel, Lawrence Serfaty, Ariane Mallat, Jean-Didier Grangé, Catherine Buffet, Yannick Bacq, Claire Wartelle, Thông Dao, Yves Benhamou, Christophe Pilette, Christine Silvain, Christos Christidis, Dominique Capron, Gérard Thiefin, Sophie Hillaire, Vincent Di Martino, Pierre Nahon, Sylvie Chevret and and ANRS CO12 CirVir group.

      Accepted manuscript online: 11 FEB 2015 06:02AM EST | DOI: 10.1002/hep.27743

  29. Hepatobiliary Malignancies

    1. The Role of hepatic resection in the treatment of hepatocellular cancer

      Sasan Roayaie, Ghalib Jibara, Parissa Tabrizian, Joong-Won Park, Jijin Yang, Lunan Yan, Myron Schwartz, Guohong Han, Francesco Izzo, Mishan Chen, Jean-Frédéric Blanc, Philip Johnson, Masatoshi Kudo, Lewis R. Roberts and Morris Sherman

      Accepted manuscript online: 11 FEB 2015 06:01AM EST | DOI: 10.1002/hep.27745

  30. Viral Hepatitis

    1. A molecular mechanism for lipophagy regulation in the liver

      Didac Carmona-Gutierrez, Andreas Zimmermann and Frank Madeo

      Accepted manuscript online: 11 FEB 2015 05:38AM EST | DOI: 10.1002/hep.27738

  31. Hepatology Elsewhere

  32. Comments from the Editors

    1. The origins of hepatobiliary and gastrointestinal physiology

      James L. Boyer

      Accepted manuscript online: 11 FEB 2015 05:34AM EST | DOI: 10.1002/hep.27737

  33. Viral Hepatitis

    1. Cost-effectiveness of hepatitis C treatment for patients in early stages of liver disease

      Andrew J. Leidner, Harrell W. Chesson, Fujie Xu, John W. Ward, Philip R. Spradling and Scott D. Holmberg

      Accepted manuscript online: 11 FEB 2015 05:34AM EST | DOI: 10.1002/hep.27736

  34. Correspondence

    1. FIB-4 as a prognostic model for patients with hepatitis B-associated hepatocellular carcinoma

      Qing Pang, Xin Sen Xu, Jing Yao Zhang, Kai Qu, Wei Chen and Chang Liu

      Accepted manuscript online: 2 FEB 2015 12:51PM EST | DOI: 10.1002/hep.27727

  35. Hepatobiliary Malignancies

    1. Predictors of survival of patients with advanced hepatocellular carcinoma who permanently discontinued sorafenib

      Massimo Iavarone, Giuseppe Cabibbo, Marco Biolato, Cristina Della Corte, Marcello Maida, Marco Barbàra, Michele Basso, Sara Vavassori, Antonio Craxì, Antonio Grieco, Carlo Cammà and Massimo Colombo

      Accepted manuscript online: 2 FEB 2015 12:51PM EST | DOI: 10.1002/hep.27729

    2. DNA Methylation-based prognosis and epidrivers in hepatocellular carcinoma

      Augusto Villanueva, Anna Portela, Sergi Sayols, Carlo Battiston, Yujin Hoshida, Jesús Méndez-González, Sandrine Imbeaud, Eric Letouzé, Virginia Hernandez-Gea, Helena Cornella, Roser Pinyol, Manel Solé, Josep Fuster, Jessica Zucman-Rossi, Vincenzo Mazzaferro, Manel Esteller, Josep M. Llovet and on behalf of the HEPTROMIC Consortium

      Accepted manuscript online: 2 FEB 2015 12:51PM EST | DOI: 10.1002/hep.27732

  36. Viral Hepatitis

    1. Differentiation of acute from chronic hepatitis C virus infection by NS5B deep sequencing: A population-level tool for incidence estimation

      Vincent Montoya, Andrea Olmstead, Naveed Z. Janjua, Patrick Tang, Jason Grebely, Darrel Cook, P. Richard Harrigan and Mel Krajden

      Accepted manuscript online: 2 FEB 2015 12:51PM EST | DOI: 10.1002/hep.27734

    2. Principles on the path to a hepatologist's enlightenment

      Scott L. Friedman

      Accepted manuscript online: 30 JAN 2015 06:44PM EST | DOI: 10.1002/hep.27733

    3. Increased risk of hepatocellular carcinoma in chronic hepatitis B patients with transient elastography-defined subclinical cirrhosis

      Mi Na Kim, Seung Up Kim, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Ki Jun Song, Young Nyun Park and Kwang-Hyub Han

      Accepted manuscript online: 30 JAN 2015 06:44PM EST | DOI: 10.1002/hep.27735

  37. Hepatobiliary Malignancies

    1. Tumor infiltrating IL-33 producing effector-memory CD8+ T cells in resected hepatocellular carcinoma prolong patient survival

      Stefan M. Brunner, Christoph Rubner, Rebecca Kesselring, Maria Martin, Eva Griesshammer, Petra Ruemmele, Thomas Stempfl, Andreas Teufel, Hans J. Schlitt and Stefan Fichtner-Feigl

      Accepted manuscript online: 30 JAN 2015 06:43PM EST | DOI: 10.1002/hep.27728

  38. Clinical Observations in Hepatology

    1. Tenofovir-associated Fanconi syndrome and nephrotic syndrome in a patient with chronic hepatitis B monoinfection

      Hyeon Seok Hwang, Cheol Whee Park and Myeong Jun Song

      Accepted manuscript online: 30 JAN 2015 06:43PM EST | DOI: 10.1002/hep.27730

  39. Viral Hepatitis

  40. Autoimmune, Cholestatic and Biliary Disease

    1. CXCL13 promotes intrahepatic CXCR5+lymphocyte homing and aberrant B cell immune responses in primary biliary cirrhosis

      Yongyin Li, Weibin Wang, Libo Tang, Xuanqiu He, Xin Yan, Xiaoyong Zhang, Youfu Zhu, Jian Sun, Yongquan Shi, Xiong Ma, Ian R. Mackay, M. Eric Gershwin, Ying Han and Jinlin Hou

      Accepted manuscript online: 27 JAN 2015 05:48PM EST | DOI: 10.1002/hep.27725

  41. Liver Biology and Pathobiology

    1. Interaction of tetraspan(in) TM4SF5 with CD44 promotes self-renewal and circulating capacities of hepatocarcinoma cells

      Doohyung Lee, Juri Na, Jihye Ryu, Hye-Jin Kim, Seo Hee Nam, Minkyung Kang, Jae Woo Jung, Mi-Sook Lee, Haeng Eun Song, Jungeun Choi, Gyu-Ho Lee, Tai Young Kim, June-Key Chung, Ki Hun Park, Sung-Hak Kim, Hyunggee Kim, Howon Seo, Pilhan Kim, Hyewon Youn and Jung Weon Lee

      Accepted manuscript online: 27 JAN 2015 05:48PM EST | DOI: 10.1002/hep.27721

  42. Viral Hepatitis

    1. Long-term effect of antiviral therapy on disease course after decompensation in patients with hepatitis B virus-related cirrhosis

      Jeong Won Jang, Jong Young Choi, Young Seok Kim, Hyun Young Woo, Sung Kyu Choi, Chang Hyeong Lee, Tae Yeob Kim, Joo Hyun Sohn, Won Young Tak and Kwang-Hyub Han

      Accepted manuscript online: 27 JAN 2015 05:47PM EST | DOI: 10.1002/hep.27723

    2. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma

      Hongli Yan, Yuan Yang, Ling Zhang, Guannan Tang, YuZhao Wang, Geng Xue, Weiping Zhou and Shuhan Sun

      Accepted manuscript online: 27 JAN 2015 05:47PM EST | DOI: 10.1002/hep.27722

    3. Treatment with ledipasvir and sofosbuvir improves patient-reported outcomes: Results from the Ion-1, 2 and 3 clinical trials

      Zobair M. Younossi, Maria Stepanova, Patrick Marcellin, Nezam Afdhal, Kris V. Kowdley, Stefan Zeuzem and Sharon L. Hunt

      Accepted manuscript online: 27 JAN 2015 05:47PM EST | DOI: 10.1002/hep.27724

  43. Reviews

    1. Strategies and Endpoints of Antifibrotic Drug Trials

      Natalie Torok, Jonathan A. Dranoff, Detlef Schuppan and Scott L. Friedman

      Accepted manuscript online: 27 JAN 2015 10:38AM EST | DOI: 10.1002/hep.27720

  44. Viral Hepatitis

    1. You have full text access to this OnlineOpen article
      All-Oral 12-Week Treatment With Daclatasvir Plus Sofosbuvir in Patients With Hepatitis C Virus Genotype 3 Infection: ALLY-3 Phase 3 Study

      David R. Nelson, James N. Cooper, Jacob P. Lalezari, Eric Lawitz, Paul J. Pockros, Norman Gitlin, Bradley F. Freilich, Ziad H. Younes, William Harlan, Reem Ghalib, Godson Oguchi, Paul J. Thuluvath, Grisell Ortiz-Lasanta, Mordechai Rabinovitz, David Bernstein, Michael Bennett, Trevor Hawkins, Natarajan Ravendhran, Aasim M. Sheikh, Peter Varunok, Kris V. Kowdley, Delphine Hennicken, Fiona McPhee, Khurram Rana, Eric A. Hughes and on behalf of the ALLY-3 Study Team

      Accepted manuscript online: 23 JAN 2015 09:33AM EST | DOI: 10.1002/hep.27726

  45. Steatohepatitis and Metabolic Liver Disease

    1. Activation of aryl hydrocarbon receptor dissociates fatty liver from insulin resistance by inducing FGF21

      Peipei Lu, Jiong Yan, Ke Liu, Wojciech G. Garbacz, Pengcheng Wang, Meishu Xu, Xiaochao Ma and Wen Xie

      Accepted manuscript online: 22 JAN 2015 04:31PM EST | DOI: 10.1002/hep.27719

  46. Viral Hepatitis

    1. A Glass Half Full: Implications of Screening for HCV in the Era of Highly Effective Antiviral Therapy

      Glen Lutchman and W. Ray Kim

      Accepted manuscript online: 22 JAN 2015 10:33AM EST | DOI: 10.1002/hep.27718

  47. Liver Failure, Cirrhosis and Portal Hypertension

    1. Metabolic and molecular responses to leucine enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis

      Cynthia Tsien, Gangarao Davuluri, Dharmvir Singh, Allawy Allawy, Gabriella AM Ten Have, Samjhana Thapaliya, John M Schulze, David Barnes, Arthur J McCullough, Marielle P.K.J. Engelen, Nicolaas E.P. Deutz and Srinivasan Dasarathy

      Accepted manuscript online: 22 JAN 2015 09:57AM EST | DOI: 10.1002/hep.27717

  48. Liver Biology and Pathobiology

    1. Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload

      Christine E. McLaren, Mary J. Emond, V. Nathan Subramaniam, Pradyumna D. Phatak, James C. Barton, Paul C. Adams, Justin B. Goh, Cameron J. McDonald, Lawrie W. Powell, Lyle C. Gurrin, Katrina J. Allen, Deborah A. Nickerson, Tin Louie, Grant A. Ramm, Gregory J. Anderson and Gordon D. McLaren

      Accepted manuscript online: 20 JAN 2015 05:19PM EST | DOI: 10.1002/hep.27711

    2. Valproic acid-induced hepatotoxicity in alpers syndrome is associated with mPTP opening dependent apoptotic sensitivity in an iPSC model

      Shengbiao Li, Jingyi Guo, Zhongfu Ying, Shen Chen, Liang Yang, Keshi Chen, Qi Long, Dajiang Qin, Duanqing Pei and Xingguo Liu

      Accepted manuscript online: 20 JAN 2015 05:19PM EST | DOI: 10.1002/hep.27712

  49. Clinical Observations in Hepatology

    1. Hepatocyte buds derived from progenitor cells repopulate regions of parenchymal extinction in human cirrhosis

      Ashley E. Stueck and Ian R. Wanless

      Accepted manuscript online: 16 JAN 2015 04:57PM EST | DOI: 10.1002/hep.27706

  50. Viral Hepatitis

    1. You have full text access to this OnlineOpen article
      Randomized trial of interferon- and ribavirin-free ombitasvir/paritaprevir/ritonavir in treatment-experienced hcv-infected patients

      Kazuaki Chayama, Kazuo Notsumata, Masayuki Kurosaki, Ken Sato, Lino Rodrigues-Jr, Carolyn Setze, Prajakta Badri, Tami Pilot-Matias, Regis A. Vilchez and Hiromitsu Kumada

      Accepted manuscript online: 16 JAN 2015 04:57PM EST | DOI: 10.1002/hep.27705

  51. Liver Injury and Regeneration

    1. A case of G-CSF/plasmapheresis induced activation of G-CSFR+ hepatic progenitors in acute-on-chronic liver failure

      Anna Chiara Piscaglia, Vincenzo Arena, Stefano Passalacqua and Antonio Gasbarrini

      Accepted manuscript online: 16 JAN 2015 04:56PM EST | DOI: 10.1002/hep.27708

  52. Liver Biology and Pathobiology

    1. A clinicopathological cohort study of liver pathology in 301 patients with HIV/AIDS

      M.W. Sonderup, H Wainwright, P Hall, H Hairwadzi and C.W.N. Spearman

      Accepted manuscript online: 16 JAN 2015 04:56PM EST | DOI: 10.1002/hep.27710

  53. Correspondence

    1. Should surgery be carried out in patients with hepatocellular carcinoma with portal hypertension?

      Tian Yang, Wan Yee Lau, Han Zhang, Mengchao Wu and Feng Shen

      Accepted manuscript online: 16 JAN 2015 04:54PM EST | DOI: 10.1002/hep.27703

    2. Reply

      Annalisa Berzigotti, Maria Reig and Jordi Bruix

      Accepted manuscript online: 16 JAN 2015 04:53PM EST | DOI: 10.1002/hep.27701

    3. RE: Response to letters to the editor

      Michael Charlton

      Accepted manuscript online: 16 JAN 2015 04:53PM EST | DOI: 10.1002/hep.27699

  54. Viral Hepatitis

    1. How to optimize HCV treatment impact on life years saved in resource-constrained countries

      Dorothée Obach, Yazdan Yazdanpanah, Gamal Esmat, Anchalee Avihingsanon, Sahar Dewedar, Nicolas Durier, Alain Attia, Wagida A. Anwar, Anthony Cousien, Pisit Tangkijvanich, Serge Paul Eholié, Wahid Doss, Aya Mostafa, Arnaud Fontanet, Mostafa K. Mohamed and Sylvie Deuffic-Burban

      Accepted manuscript online: 10 JAN 2015 04:05AM EST | DOI: 10.1002/hep.27691

  55. Steatohepatitis and Metabolic Liver Disease

    1. Altered hepatic gene expression in non-alcoholic fatty liver disease is associated with lower hepatic n-3 and n-6 polyunsaturated fatty acids

      Bianca M. Arendt, Elena M. Comelli, David W. L. Ma, Wendy Lou, Anastasia Teterina, TaeHyung Kim, Scott K. Fung, David K. H. Wong, Ian McGilvray, Sandra E. Fischer and Johane P. Allard

      Accepted manuscript online: 10 JAN 2015 04:05AM EST | DOI: 10.1002/hep.27695

  56. Viral Hepatitis

  57. Liver Biology and Pathobiology

    1. Impaired uptake of conjugated bile acids and Hepatitis B Virus preS1-binding in Na+-taurocholate cotransporting polypeptide knockout mice

      Davor Slijepcevic, Christina Kaufman, Catharina G.K. Wichers, Eduardo H. Gilglioni, Florian A. Lempp, Suzanne Duijst, Dirk R. de Waart, Ronald P.J. Oude Elferink, Walter Mier, Bruno Stieger, Ulrich Beuers, Stephan Urban and Stan F.J. van de Graaf

      Accepted manuscript online: 10 JAN 2015 04:04AM EST | DOI: 10.1002/hep.27694

  58. Viral Hepatitis

    1. Interplay of Interleukin-22 and its binding protein in controlling liver scarring

      Bin Gao

      Accepted manuscript online: 10 JAN 2015 04:03AM EST | DOI: 10.1002/hep.27688

  59. Comments from the Editors

    1. What is hepatology looking for?

      Michael H. Nathanson

      Accepted manuscript online: 10 JAN 2015 03:51AM EST | DOI: 10.1002/hep.27690

  60. Liver Biology and Pathobiology

    1. Adaptive remodeling of the biliary architecture underlies liver homeostasis

      Kota Kaneko, Kenji Kamimoto, Atsushi Miyajima and Tohru Itoh

      Accepted manuscript online: 8 JAN 2015 02:14PM EST | DOI: 10.1002/hep.27685

  61. Viral Hepatitis

    1. Reappearance of serum HBV DNA in patients with hepatitis B surface antigen seroclearance

      Masato Nakamura, Tatsuo Kanda, Shingo Nakamoto, Yuki Haga, Reina Sasaki, Xia Jiang, Shin Yasui, Makoto Arai and Osamu Yokosuka

      Accepted manuscript online: 8 JAN 2015 02:10PM EST | DOI: 10.1002/hep.27693

  62. Hepatobiliary Malignancies

    1. IL-33 facilitates oncogene induced cholangiocarcinoma in mice by an IL-6 sensitive mechanism

      Daisaku Yamada, Sumera Rizvi, Nataliya Razumilava, Steven F. Bronk, Jaime I. Davila, Mia D. Champion, Mitesh J. Borad, Jorge A. Bezerra, Xin Chen and Gregory J. Gores

      Accepted manuscript online: 7 JAN 2015 11:57AM EST | DOI: 10.1002/hep.27687

  63. Steatohepatitis and Metabolic Liver Disease

    1. The Small GTPase Rab7 as a central regulator of hepatocellular lipophagy

      Barbara Schroeder, Ryan J. Schulze, Shaun G. Weller, Arthur C. Sletten, Carol A. Casey and Mark A. McNiven

      Accepted manuscript online: 6 JAN 2015 01:11PM EST | DOI: 10.1002/hep.27667

    2. Nonalcoholic fatty liver disease: Fibrosis portends a worse prognosis

      Dawn M Torres and Stephen A Harrison

      Accepted manuscript online: 6 JAN 2015 01:11PM EST | DOI: 10.1002/hep.27680

  64. Viral Hepatitis

    1. Sofosbuvir compassionate use program for patients with severe recurrent hepatitis C following liver transplantation

      Xavier Forns, Michael Charlton, Jill Denning, John G McHutchison, William T. Symonds, Diana Brainard, Theo Brandt-Sarif, Paul Chang, Valerie Kivett, Lluís Castells, Martín Prieto, Robert J. Fontana, Thomas F. Baumert, Audrey Coilly, Maria Carlota Londoño and François Habersetzer

      Accepted manuscript online: 29 DEC 2014 01:10PM EST | DOI: 10.1002/hep.27681

  65. Liver Failure, Cirrhosis and Portal Hypertension

    1. Caffeine ameliorates hemodynamic derangements and portosystemic collaterals in cirrhotic rats

      Shao-Jung Hsu, Fa-Yauh Lee, Sun-Sang Wang, I-Fang Hsin, Te-Yueh Lin, Hui-Chun Huang, Ching-Chih Chang, Chiao-Lin Chuang, Hsin-Ling Ho, Han-Chieh Lin and Shou-Dong Lee

      Accepted manuscript online: 29 DEC 2014 01:02PM EST | DOI: 10.1002/hep.27679

  66. Liver Biology and Pathobiology

    1. FXR-induced lysine-specific histone demethylase, LSD1, reduces hepatic bile acid levels and protects the liver against bile acid toxicity

      Young-Chae Kim, Sungsoon Fang, Sangwon Byun, Sunmi Seok, Byron Kemper and Jongsook KimKemper

      Accepted manuscript online: 24 DEC 2014 06:08PM EST | DOI: 10.1002/hep.27677

  67. Viral Hepatitis

    1. Low risk of liver decompensation among human immunodeficiency virus/hepatitis c virus-coinfected patients with mild fibrosis in the short-term

      Juan Macías, María Mancebo, Manuel Márquez, Dolores Merino, Francisco Téllez, Antonio Rivero, Miguel A. von Wichmann, Luis F. López-Cortés, Nicolás Merchante, Jesús Santos, Miguel Raffo, Montserrat Pérez-Pérez, Ángela Camacho, Jose A. Iribarren and Juan A. Pineda

      Accepted manuscript online: 24 DEC 2014 06:07PM EST | DOI: 10.1002/hep.27674

  68. Autoimmune, Cholestatic and Biliary Disease

    1. Ezrin finds its groove in cholangiocytes

      Laura Fouassier and Romina Fiorotto

      Accepted manuscript online: 24 DEC 2014 06:07PM EST | DOI: 10.1002/hep.27675

  69. Liver Failure, Cirrhosis and Portal Hypertension

    1. rAAV8-mediated inhibition of miRNA-21 protects mice against the lethal schistosome infection by repressing both IL-13 and TGF-β1 pathways

      Xing He, Jun Xie, Dongmei Zhang, Qin Su, Xue Sai, Ruipu Bai, Chao Chen, Xufeng Luo, Guangping Gao and Weiqing Pan

      Accepted manuscript online: 24 DEC 2014 06:07PM EST | DOI: 10.1002/hep.27671

  70. Correspondence

    1. Evidence against a role of serotonin in liver regeneration in humans

      Edris M. Alkozai, Martijn vanFaassen, Ido P. Kema, Robert J. Porte and Ton Lisman

      Accepted manuscript online: 24 DEC 2014 06:06PM EST | DOI: 10.1002/hep.27673

  71. Steatohepatitis and Metabolic Liver Disease

    1. Biochemical markers, liver biopsy or magnetic resonance elastography to detect or exclude advanced fibrosis in patients with NAFLD

      Huseyin Kayadibi, Erdim Sertoglu and Metin Uyanik

      Accepted manuscript online: 24 DEC 2014 06:06PM EST | DOI: 10.1002/hep.27670

  72. Correspondence

    1. Evidence for serotonin as an inducer of liver regeneration in humans - further investigations

      Patrick Starlinger, Christine Brostjan and Thomas Gruenberger

      Accepted manuscript online: 24 DEC 2014 06:06PM EST | DOI: 10.1002/hep.27672

  73. Viral Hepatitis

    1. The ‘dose' of exercise and its effects beyond weight loss

      Mary Rinella

      Accepted manuscript online: 24 DEC 2014 04:26AM EST | DOI: 10.1002/hep.27669

  74. Correspondence

    1. Central obesity induces a greater risk of hepatocellular carcinoma than general obesity

      Qing Pang, Jing Yao Zhang, Kai Qu, Si Dong Song, Su Shun Liu and Chang Liu

      Accepted manuscript online: 24 DEC 2014 02:46AM EST | DOI: 10.1002/hep.27668

  75. Viral Hepatitis

    1. Association of hepatitis C virus infection with incidence and progression of chronic kidney disease in a large cohort of US veterans

      Miklos Z Molnar, Hazem M Alhourani, Barry M Wall, Jun L Lu, Elani Streja, Kamyar Kalantar-Zadeh and Csaba P Kovesdy

      Accepted manuscript online: 20 DEC 2014 07:48AM EST | DOI: 10.1002/hep.27664

  76. Hepatobiliary Malignancies

    1. CXCR4 inhibition in tumor microenvironment facilitates anti-PD-1 immunotherapy in sorafenib-treated HCC in mice

      Yunching Chen, Rakesh R. Ramjiawan, Thomas Reiberger, Mei R. Ng, Tai Hato, Yuhui Huang, Hiroki Ochiai, Shuji Kitahara, Elizabeth C. Unan, Tejaswini P. Reddy, Christopher Fan, Peigen Huang, Nabeel Bardeesy, Andrew X. Zhu, Rakesh K. Jain and Dan G. Duda

      Accepted manuscript online: 20 DEC 2014 07:48AM EST | DOI: 10.1002/hep.27665

  77. Viral Hepatitis

    1. Costly choices for treating Wilson disease

      Michael L. Schilsky, Eve A. Roberts, Sihoun Hahn and Frederick Askari

      Accepted manuscript online: 18 DEC 2014 08:31PM EST | DOI: 10.1002/hep.27663

  78. Steatohepatitis and Metabolic Liver Disease

    1. The impact of phlebotomy in nonalcoholic fatty liver disease: A prospective randomized controlled trial

      LA Adams, DH Crawford, K Stuart, MJ House, TG St.Pierre, M Webb, H Ching, J Kava, M Bynevelt, GC MacQuillan, G Garas, OT Ayonrinde, TA Mori, KD Croft, X Niu, GP Jeffrey and JK Olynyk

      Accepted manuscript online: 18 DEC 2014 03:14PM EST | DOI: 10.1002/hep.27662

  79. Correspondence

    1. Could abnormal neutrophil-platelet interactions and complex formation contribute to oxidative stress and organ failure in cirrhosis?

      Jonathan P Sturgeon, Godhev K Manakkat Vijay, Jennifer Ryan, William Bernal and Debbie L Shawcross

      Accepted manuscript online: 18 DEC 2014 03:08PM EST | DOI: 10.1002/hep.27661

  80. Hepatology Elsewhere

    1. Is petoxifylline still an option in severe alcoholic hepatitis?

      Juan Caballeria

      Accepted manuscript online: 12 DEC 2014 07:20PM EST | DOI: 10.1002/hep.27657

  81. Correspondence

    1. Reply: HEP-14-2331 TM6SF2 as a genetic risk factor for fibrosis

      Silvia Sookoian and Carlos J. Pirola

      Accepted manuscript online: 12 DEC 2014 07:16PM EST | DOI: 10.1002/hep.27655

  82. Viral Hepatitis

    1. Determining the fate of hepatic cells by lineage tracing: Facts and pitfalls

      Frédéric P. Lemaigre

      Accepted manuscript online: 12 DEC 2014 07:16PM EST | DOI: 10.1002/hep.27659

  83. Correspondence

    1. TM6SF2 as a genetic risk factor for fibrosis

      Ann K. Daly, Christopher P. Day, Yang-Lin Liu and Quentin M. Anstee

      Accepted manuscript online: 12 DEC 2014 07:06PM EST | DOI: 10.1002/hep.27656

  84. Liver Injury and Regeneration

    1. FGF2lmw attenuates hepatic fibrosis via epigenetic downregulation of Delta-like1

      Ruo-Lang Pan, Li-Xin Xiang, Ping Wang, Xiao-Yuan Liu, Li Nie, Wendong Huang and Jian-Zhong Shao

      Accepted manuscript online: 11 DEC 2014 06:33AM EST | DOI: 10.1002/hep.27649

  85. Correspondence

    1. Reply

      Yeon Seok Seo, Chang Ho Jung, Tae Hyung Kim, Sun Young Yim and Soon Ho Um

      Accepted manuscript online: 6 DEC 2014 11:20AM EST | DOI: 10.1002/hep.27646

  86. Steatohepatitis and Metabolic Liver Disease

    1. You have full text access to this OnlineOpen article
      Ezetimibe for the treatment of nonalcoholic steatohepatitis: Assessment by novel MRI and MRE in a randomized trial (MOZART Trial)

      Rohit Loomba, Claude B. Sirlin, Brandon Ang, Ricki Bettencourt, Rashmi Jain, Joanie Salotti, Linda Soaft, Jonathan Hooker, Yuko Kono, Archana Bhatt, Laura Hernandez, Phirum Nguyen, Mazen Noureddin, William Haufe, Catherine Hooker, Meng Yin, Richard Ehman, Grace Lin, Mark Valasek, David Brenner, Lisa Richards and San Diego Integrated Research Consortium (SINC)

      Accepted manuscript online: 6 DEC 2014 11:20AM EST | DOI: 10.1002/hep.27647

  87. Liver Biology and Pathobiology

    1. Liver X receptors balance lipid stores in hepatic stellate cells via Rab18, a retinoid responsive lipid droplet protein

      Fiona O'Mahony, Kevin Wroblewski, Sheila M. O'Byrne, Hongfeng Jiang, Kara Clerkin, Jihane Benhammou, William S. Blaner and Simon W. Beaven

      Accepted manuscript online: 6 DEC 2014 11:11AM EST | DOI: 10.1002/hep.27645

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