Hepatology

Copyright © 2013 American Association for the Study of Liver Diseases

Cover image for Vol. 57 Issue 5

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Michael H. Nathanson

Impact Factor: 11.665

ISI Journal Citation Reports © Ranking: 2011: 2/74 (Gastroenterology & Hepatology)

Online ISSN: 1527-3350

Associated Title(s): Clinical Liver Disease, Liver Transplantation

  1. Hepatology Elsewhere

    1. Interferon-lambda polymorphisms and hepatitis C virus clearance revisited

      Joachim Lupberger, Daniel J. Felmlee and Thomas F. Baumert

      Article first published online: 17 MAY 2013 | DOI: 10.1002/hep.26443

  2. Liver Injury/Regeneration

    1. ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury

      Naoko Kamo, Bibo Ke, Amir A. Ghaffari, Xiu-da Shen, Ronald W. Busuttil, Genhong Cheng and Jerzy W. Kupiec-Weglinski

      Article first published online: 15 MAY 2013 | DOI: 10.1002/hep.26320

  3. Viral Hepatitis

    1. Hepatitis B virus hepatotropism is mediated by specific receptor recognition in the liver and not restricted to susceptible hosts

      Alexa Schieck, Andreas Schulze, Caroline Gähler, Thomas Müller, Uwe Haberkorn, Alexander Alexandrov, Stephan Urban and Walter Mier

      Article first published online: 15 MAY 2013 | DOI: 10.1002/hep.26211

  4. Liver Biology/Pathobiology

    1. Implication of the proprotein convertases in iron homeostasis: Proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin

      Johann Guillemot, Maryssa Canuel, Rachid Essalmani, Annik Prat and Nabil G. Seidah

      Article first published online: 15 MAY 2013 | DOI: 10.1002/hep.26297

  5. Hepatobiliary Malignancies

    1. Postoperative peg-interferon plus ribavirin is associated with reduced recurrence of hepatitis C virus-related hepatocellular carcinoma

      Yao-Chun Hsu, Hsiu J. Ho, Ming-Shiang Wu, Jaw-Town Lin and Chun-Ying Wu

      Article first published online: 15 MAY 2013 | DOI: 10.1002/hep.26300

    2. Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520

      Yun-Yong Park, Sang-Bae Kim, Hee Dong Han, Bo Hwa Sohn, Ji Hoon Kim, Jiyong Liang, Yiling Lu, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Gordon B. Mills, Anil K. Sood and Ju-Seog Lee

      Article first published online: 15 MAY 2013 | DOI: 10.1002/hep.26310

  6. Steatohepatitis/Metabolic Liver Disease

    1. Liver fatty acid binding protein (L-Fabp) modulates murine stellate cell activation and diet-induced nonalcoholic fatty liver disease

      Anping Chen, Youcai Tang, Victoria Davis, Fong-Fu Hsu, Susan M. Kennedy, Haowei Song, John Turk, Elizabeth M. Brunt, Elizabeth P. Newberry and Nicholas O. Davidson

      Article first published online: 15 MAY 2013 | DOI: 10.1002/hep.26318

  7. Correspondence

    1. Donor-derived long-lived intragraft leukocytes are likely generated by hematopoietic stem/progenitor cells in liver

      Xiao Qi Wang, Cindy K.Y. Cheung and Chung Mau Lo

      Article first published online: 15 MAY 2013 | DOI: 10.1002/hep.26114

  8. Erratum

    1. You have free access to this content
      Correction

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26291

      This article corrects:

      Receptor for activated C kinase 1 promotes hepatocellular carcinoma growth by enhancing mitogen-activated protein kinase kinase 7 activity†‡

      Vol. 57, Issue 1, 140–151, Article first published online: 7 JAN 2013

  9. Reviews

    1. Albumin: Pathophysiologic basis of its role in the treatment of cirrhosis and its complications

      Rita Garcia-Martinez, Paolo Caraceni, Mauro Bernardi, Pere Gines, Vicente Arroyo and Rajiv Jalan

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26338

  10. Hepatobiliary Malignancies

    1. Polymorphisms in the coding region of X-ray repair complementing group 4 and aflatoxin B1-related hepatocellular carcinoma

      Xi-Dai Long, Jin-Guang Yao, Zhi Zeng, Yun Ma, Xiao-Ying Huang, Zhong-Hua Wei, Min Liu, Jian-Jun Zhang, Feng Xue, Bo Zhai and Qiang Xia

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26311

    2. αB-crystallin complexes with 14-3-3ζ to induce epithelial-mesenchymal transition and resistance to sorafenib in hepatocellular carcinoma

      Xiao-Yong Huang, Ai-Wu Ke, Guo-Ming Shi, Xin Zhang, Chi Zhang, Ying-Hong Shi, Xiao-Ying Wang, Zhen-Bin Ding, Yong-Sheng Xiao, Jun Yan, Shuang-Jian Qiu, Jia Fan and Jian Zhou

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26255

    3. Soluble receptor for advanced glycation end products and risk of liver cancer

      Kristin A. Moy, Li Jiao, Neal D. Freedman, Stephanie J. Weinstein, Rashmi Sinha, Jarmo Virtamo, Demetrius Albanes and Rachael Z. Stolzenberg-Solomon

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26264

  11. Viral Hepatitis

    1. The antimalarial ferroquine is an inhibitor of hepatitis C virus

      Thibaut Vausselin, Noémie Calland, Sandrine Belouzard, Véronique Descamps, Florian Douam, François Helle, Catherine François, Dimitri Lavillette, Gilles Duverlie, Ahmed Wahid, Lucie Fénéant, Laurence Cocquerel, Yann Guérardel, Czeslaw Wychowski, Christophe Biot and Jean Dubuisson

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26273

  12. Liver Biology/Pathobiology

    1. Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice

      Kei Kiyohashi, Sei Kakinuma, Akihide Kamiya, Naoya Sakamoto, Sayuri Nitta, Hideto Yamanaka, Kouhei Yoshino, Junko Fujiki, Miyako Murakawa, Akiko Kusano-Kitazume, Hiromichi Shimizu, Ryuichi Okamoto, Seishin Azuma, Mina Nakagawa, Yasuhiro Asahina, Naoki Tanimizu, Akira Kikuchi, Hiromitsu Nakauchi and Mamoru Watanabe

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26293

  13. Liver Failure/Cirrhosis/Portal Hypertension

    1. Role of procoagulant microparticles in mediating complications and outcome of acute liver injury/acute liver failure

      R. Todd Stravitz, Regina Bowling, Robert L. Bradford, Nigel S. Key, Sam Glover, Leroy R. Thacker and Don A. Gabriel

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26307

  14. Liver Biology/Pathobiology

    1. Scavenger receptor BI and ABCG5/G8 differentially impact biliary sterol secretion and reverse cholesterol transport in mice

      Arne Dikkers, Jan Freak de Boer, Wijtske Annema, Albert K. Groen and Uwe J.F. Tietge

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26316

  15. Hepatobiliary Malignancies

    1. MAT2B-GIT1 interplay activates MEK1/ERK 1 and 2 to induce growth in human liver and colon cancer

      Hui Peng, Lily Dara, Tony W.H. Li, Yuhua Zheng, Heping Yang, Maria Lauda Tomasi, Ivan Tomasi, Pasquale Giordano, Jose M. Mato and Shelly C. Lu

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26258

  16. Autoimmune, Cholestatic and Biliary Disease

    1. GABA induces the differentiation of small into large cholangiocytes by activation of Ca2+/CaMK I-dependent adenylyl cyclase 8

      Romina Mancinelli, Antonio Franchitto, Shannon Glaser, Fanyin Meng, Paolo Onori, Sharon DeMorrow, Heather Francis, Julie Venter, Guido Carpino, Kimberley Baker, Yuyan Han, Yoshiyuki Ueno, Eugenio Gaudio and Gianfranco Alpini

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26308

  17. Hepatobiliary Malignancies

    1. MicroRNA-140-5p suppresses tumor growth and metastasis by targeting transforming growth factor β receptor 1 and fibroblast growth factor 9 in hepatocellular carcinoma

      Hao Yang, Feng Fang, Ruimin Chang and Lianyue Yang

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26315

  18. Steatohepatitis/Metabolic Liver Disease

    1. Intestinal microbiota in patients with nonalcoholic fatty liver disease

      Marialena Mouzaki, Elena M. Comelli, Bianca M. Arendt, Julia Bonengel, Scott K. Fung, Sandra E. Fischer, Ian D. McGilvray and Johane P. Allard

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26319

  19. Liver Biology/Pathobiology

    1. Taurolithocholate-induced MRP2 retrieval involves MARCKS phosphorylation by protein kinase Cϵ in HUH-NTCP Cells

      Christopher M. Schonhoff, Cynthia R. L. Webster and M. Sawkat Anwer

      Article first published online: 14 MAY 2013 | DOI: 10.1002/hep.26333

  20. Editorial

    1. In the eye of the B-holder: Natural history of chronic hepatitis B

      Surakit Pungpapong and W. Ray Kim

      Article first published online: 8 MAY 2013 | DOI: 10.1002/hep.26356

    2. C-reactive protein, a prognostic marker in hepatocellular carcinoma

      Jean-François Dufour

      Article first published online: 8 MAY 2013 | DOI: 10.1002/hep.26250

  21. Viral Hepatitis

    1. Plasma interferon-gamma-inducible protein-10 (IP-10) levels during acute hepatitis C virus infection

      Jason Grebely, Jordan J. Feld, Tanya Applegate, Gail V. Matthews, Margaret Hellard, Alana Sherker, Kathy Petoumenos, Geng Zang, Ineke Shaw, Barbara Yeung, Jacob George, Suzy Teutsch, John M. Kaldor, Vera Cherepanov, Julie Bruneau, Naglaa H. Shoukry, Andrew R. Lloyd and Gregory J. Dore

      Article first published online: 8 MAY 2013 | DOI: 10.1002/hep.26263

  22. Hepatobiliary Malignancies

    1. Tissue metabolomics of hepatocellular carcinoma: Tumor energy metabolism and the role of transcriptomic classification

      Diren Beyoğlu, Sandrine Imbeaud, Olivier Maurhofer, Paulette Bioulac-Sage, Jessica Zucman-Rossi, Jean-François Dufour and Jeffrey R. Idle

      Article first published online: 8 MAY 2013 | DOI: 10.1002/hep.26350

  23. Autoimmune, Cholestatic and Biliary Disease

    1. Immunoglobulin G4+ clones identified by next-generation sequencing dominate the B cell receptor repertoire in immunoglobulin G4 associated cholangitis

      Lucas J. Maillette de Buy Wenniger, Marieke E. Doorenspleet, Paul L. Klarenbeek, Joanne Verheij, Frank Baas, Ronald P. Oude Elferink, Paul P. Tak, Niek de Vries and Ulrich Beuers

      Article first published online: 8 MAY 2013 | DOI: 10.1002/hep.26232

  24. Editorials

    1. Immunoglobulin G4-associated cholangitis: Dominating immunoglobulin G4-positive clones within the B-cell receptor repertoire indicate light at the end of a long tunnel

      Michael P. Manns

      Article first published online: 7 MAY 2013 | DOI: 10.1002/hep.26330

  25. Steatohepatitis and Metabolic Liver Disease

    1. Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents

      Maximilian Hatting, Gang Zhao, Fabienne Schumacher, Gernot Sellge, Malika Al Masaoudi, Nikolaus Gaβler, Mark Boekschoten, Michael Müller, Christian Liedtke, Francisco Javier Cubero and Christian Trautwein

      Article first published online: 6 MAY 2013 | DOI: 10.1002/hep.26271

  26. Viral Hepatitis

    1. You have full text access to this OnlineOpen article
      Chronic hepatitis C virus (HCV) disease burden and cost in the United States

      Homie Razavi, Antoine C. ElKhoury, Elamin Elbasha, Chris Estes, Ken Pasini, Thierry Poynard and Ritesh Kumar

      Article first published online: 6 MAY 2013 | DOI: 10.1002/hep.26218

  27. Original Articles

    1. The ART of decision making: Retreatment with transarterial chemoembolization in patients with hepatocellular carcinoma

      Wolfgang Sieghart, Florian Hucke, Matthias Pinter, Ivo Graziadei, Wolfgang Vogel, Christian Müller, Harald Heinzl, Michael Trauner and Markus Peck-Radosavljevic

      Article first published online: 3 MAY 2013 | DOI: 10.1002/hep.26256

  28. Viral Hepatitis

    1. You have full text access to this OnlineOpen article
      Efficacy of tenofovir disoproxil fumarate at 240 weeks in patients with chronic hepatitis B with high baseline viral load

      Stuart C. Gordon, Zahary Krastev, Andrzej Horban, Jörg Petersen, Jan Sperl, Phillip Dinh, Eduardo B. Martins, Leland J. Yee, John F. Flaherty, Kathryn M. Kitrinos, Vinod K. Rustgi and Patrick Marcellin

      Article first published online: 3 MAY 2013 | DOI: 10.1002/hep.26277

  29. Hepatobiliary Malignancies

    1. Hepatocellular carcinoma-associated mesenchymal stem cells promote hepatocarcinoma progression: Role of the S100A4-miR155-SOCS1-MMP9 axis

      Xin-Long Yan, Ya-Li Jia, Lin Chen, Quan Zeng, Jun-Nian Zhou, Chun-Jiang Fu, Hai-Xu Chen, Hong-Feng Yuan, Zhi-Wei Li, Lei Shi, Ying-Chen Xu, Jing-Xue Wang, Xiao-Mei Zhang, Li-Juan He, Chao Zhai, Wen Yue and Xue-Tao Pei

      Article first published online: 1 MAY 2013 | DOI: 10.1002/hep.26257

  30. Liver Failure, Cirrhosis and Portal Hypertension

    1. Embolization of large spontaneous portosystemic shunts for refractory hepatic encephalopathy: A multicenter survey on safety and efficacy

      Wim Laleman, Macarena Simon-Talero, Geert Maleux, Mercedes Perez, Koen Ameloot, German Soriano, Jordi Villalba, Juan-Carlos Garcia-Pagan, Marta Barrufet, Rajiv Jalan, Jocelyn Brookes, Evangelos Thalassinos, Andrew K. Burroughs, Juan Cordoba and Frederik Nevens, the EASL-CLIF-Consortium

      Article first published online: 1 MAY 2013 | DOI: 10.1002/hep.26314

    2. Dietary fructose in nonalcoholic fatty liver disease

      Miriam B. Vos and Joel E. Lavine

      Article first published online: 1 MAY 2013 | DOI: 10.1002/hep.26299

  31. Autoimmune, Cholestatic and Biliary Disease

    1. Predictors of poor outcome in patients with autoimmune hepatitis: A population-based study

      Jing Hieng Ngu, Richard Blair Gearry, Chris Miles Frampton and Catherine A.M. Stedman

      Article first published online: 1 MAY 2013 | DOI: 10.1002/hep.26290

  32. Hepatobiliary Malignancies

    1. Identification of novel serum biomarkers of hepatocellular carcinoma using glycomic analysis

      Toshiya Kamiyama, Hideki Yokoo, Jun-Ichi Furukawa, Masaki Kurogochi, Tomoaki Togashi, Nobuaki Miura, Kazuaki Nakanishi, Hirofumi Kamachi, Tatsuhiko Kakisaka, Yosuke Tsuruga, Masato Fujiyoshi, Akinobu Taketomi, Shin-Ichiro Nishimura and Satoru Todo

      Article first published online: 26 APR 2013 | DOI: 10.1002/hep.26262

  33. Liver Biology/Pathobiology

    1. Genome-wide MicroRNA and messenger RNA profiling in rodent liver development implicates mir302b and mir20a in repressing transforming growth factor-beta signaling

      Wei Wei, Juan Hou, Olivia Alder, Xin Ye, Sam Lee, Rebecca Cullum, Andy Chu, Yongjun Zhao, Stephanie M. Warner, Darryl A. Knight, Decheng Yang, Steven J.M. Jones, Marco A. Marra and Pamela A. Hoodless

      Article first published online: 26 APR 2013 | DOI: 10.1002/hep.26252

  34. Hepatobiliary Malignancies

    1. SIRT2 overexpression in hepatocellular carcinoma mediates epithelial to mesenchymal transition by protein kinase B/glycogen synthase kinase-3β/β-catenin signaling

      Juan Chen, Anthony W.H. Chan, Ka-Fai To, Weixian Chen, Zhenzhen Zhang, Jihua Ren, Chunli Song, Yue-Sun Cheung, Paul B.S. Lai, Suk-Hang Cheng, Margaret H.L. Ng, Ailong Huang and Ben C.B. Ko

      Article first published online: 26 APR 2013 | DOI: 10.1002/hep.26278

  35. Correspondence

    1. Immediate intraportal transplantation of human bone marrow mesenchymal stem cells prevents death from fulminant hepatic failure in pigs

      Tao Wei and Yi Lv

      Article first published online: 26 APR 2013 | DOI: 10.1002/hep.26143

    2. Bayesian prediction for liver fibrosis staging: Combined use of elastography and serum fibrosis markers

      Utaroh Motosugi, Tomoaki Ichikawa, Tsutomu Araki, Masanori Matsuda, Hideki Fujii and Nobuyuki Enomoto

      Article first published online: 26 APR 2013 | DOI: 10.1002/hep.26144

  36. Viral Hepatitis

    1. Sustained hepatitis C virus clearance and increased hepatitis B surface antigen seroclearance in patients with dual chronic hepatitis C and B during posttreatment follow-up

      Ming-Lung Yu, Chuan-Mo Lee, Chi-Ling Chen, Wan-Long Chuang, Sheng-Nan Lu, Chen-Hua Liu, Shun-Sheng Wu, Li-Ying Liao, Hsing-Tao Kuo, You-Chen Chao, Shui-Yi Tung, Sien-Sing Yang, Jia-Horng Kao, Wei-Wen Su, Chih-Lin Lin, Hung-Chih Yang, Pei-Jer Chen, Ding-Shinn Chen and Chun-Jen Liu, for the Taiwan Liver-Net Consortium

      Article first published online: 26 APR 2013 | DOI: 10.1002/hep.26266

  37. Steatohepatitis/Metabolic Liver Disease

    1. Selective hepatic insulin resistance in a murine model heterozygous for a mitochondrial trifunctional protein defect

      R. Scott Rector, E. Matthew Morris, Suzanne Ridenhour, Grace M. Meers, Fong-Fu Hsu, John Turk and Jamal A. Ibdah

      Article first published online: 26 APR 2013 | DOI: 10.1002/hep.26285

  38. Liver Biology/Pathobiology

    1. Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1

      Petia Jeliazkova, Simone Jörs, Marcel Lee, Ursula Zimber-Strobl, Jorge Ferrer, Roland M. Schmid, Jens T. Siveke and Fabian Geisler

      Article first published online: 17 APR 2013 | DOI: 10.1002/hep.26254

  39. Hepatobiliary Malignancies

    1. The mTOR pathway in hepatic malignancies

      Mamatha Bhat, Nahum Sonenberg and Gregory J. Gores

      Article first published online: 17 APR 2013 | DOI: 10.1002/hep.26323

  40. Correspondence

    1. Overestimation of hematopoietic stem cell frequencies in human liver grafts

      Sean R.R. Hall, Alexander Pedroza-Gonzalez, Qiuwei Pan, Hugo W. Tilanus, Jeroen de Jonge, Gerard Wagemaker and Luc J.W. van der Laan

      Article first published online: 8 APR 2013 | DOI: 10.1002/hep.26119

  41. Steatohepatitis/Metabolic Liver Disease

    1. You have full text access to this OnlineOpen article
      Clinical effect and safety profile of recombinant human lysosomal acid lipase in patients With cholesteryl ester storage disease

      Manisha Balwani, Catherine Breen, Gregory M. Enns, Patrick B. Deegan, Tomas Honzík, Simon Jones, John P. Kane, Vera Malinova, Reena Sharma, Eveline O. Stock, Vassili Valayannopoulos, J. Edmond Wraith, Jennifer Burg, Stephen Eckert, Eugene Schneider and Anthony G. Quinn

      Article first published online: 28 MAR 2013 | DOI: 10.1002/hep.26289

  42. Hepatobiliary Malignancies

    1. Health care costs associated with hepatocellular carcinoma: A population-based study

      Hla-Hla Thein, Wanrudee Isaranuwatchai, Michael A. Campitelli, Jordan J. Feld, Eric Yoshida, Morris Sherman, Jeffrey S. Hoch, Stuart Peacock, Murray D. Krahn and Craig C. Earle

      Article first published online: 15 MAR 2013 | DOI: 10.1002/hep.26231

  43. Correspondence

    1. Correspondence

      George N. Ioannou, Christopher L. Bryson, Noel S. Weiss, John D. Scott and Edward J. Boyko

      Article first published online: 14 MAR 2013 | DOI: 10.1002/hep.26171

    2. Retinoids counteract insulin resistance and liver steatosis: What's the potential mechanism?

      Nadia Panera, Sara Ceccarelli, Cristiano De Stefanis, Valerio Nobili and Anna Alisi

      Article first published online: 14 MAR 2013 | DOI: 10.1002/hep.26213

  44. Viral Hepatitis

    1. Myristoylated PreS1-domain of the hepatitis B virus L-protein mediates specific binding to differentiated hepatocytes

      Anja Meier, Stefan Mehrle, Thomas S. Weiss, Walter Mier and Stephan Urban

      Article first published online: 14 MAR 2013 | DOI: 10.1002/hep.26181

  45. Liver Biology/Pathobiology

    1. Pasireotide is more effective than octreotide in reducing hepatorenal cystogenesis in rodents with polycystic kidney and liver diseases

      Tatyana V. Masyuk, Brynn N. Radtke, Angela J. Stroope, Jesús M. Banales, Sergio A. Gradilone, Bing Huang, Anatoliy I. Masyuk, Marie C. Hogan, Vicente E. Torres and Nicholas F. LaRusso

      Article first published online: 6 MAR 2013 | DOI: 10.1002/hep.26140

  46. Viral Hepatitis

    1. Long-term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection

      Tetsuya Hosaka, Fumitaka Suzuki, Masahiro Kobayashi, Yuya Seko, Yusuke Kawamura, Hitomi Sezaki, Norio Akuta, Yoshiyuki Suzuki, Satoshi Saitoh, Yasuji Arase, Kenji Ikeda, Mariko Kobayashi and Hiromitsu Kumada

      Article first published online: 6 MAR 2013 | DOI: 10.1002/hep.26180

  47. Correspondence

    1. Circulating MicroRNA-122 signature in nonalcoholic fatty liver disease and cardiovascular disease: A new endocrine system in metabolic syndrome

      Carlos J. Pirola, Tomas FernÁndez Gianotti, Gustavo O. CastaÑo and Silvia Sookoian

      Article first published online: 6 MAR 2013 | DOI: 10.1002/hep.26116

    2. Decreased risk of liver cancer with thiazolidinediones therapy in patients with type 2 diabetes: results from a meta-analysis

      Feng Wang, Shu-Zhi Zhao, Ming-Yue Zhang, Yan-Lei Ma, Peng Zhang and Huan-Long Qin

      Article first published online: 15 FEB 2013 | DOI: 10.1002/hep.26259

  48. Hepatobiliary Malignancies

    1. Impairment of CD4+ cytotoxic T cells predicts poor survival and high recurrence rates in patients with hepatocellular carcinoma

      Junliang Fu, Zheng Zhang, Lin Zhou, Zhaorui Qi, Shaojun Xing, Jiyun Lv, Jianfei Shi, Baoyun Fu, Zhenwen Liu, Ji-Yuan Zhang, Lei Jin, Yulai Zhao, George K.K. Lau, Jingmin Zhao and Fu-Sheng Wang

      Article first published online: 15 FEB 2013 | DOI: 10.1002/hep.26054

  49. Liver Failure, Cirrhosis and Portal Hypertension

    1. Hepatopulmonary syndrome: Favorable outcomes in the MELD exception era

      Vivek N. Iyer, Karen L. Swanson, Rodrigo Cartin-Ceba, Ross A. Dierkhising, Charles B. Rosen, Julie K. Heimbach, Russell H. Wiesner and Michael J. Krowka

      Article first published online: 15 FEB 2013 | DOI: 10.1002/hep.26070

  50. Erratum

    1. You have free access to this content
      Correction

      Jason D. Coombes and Wing-Kin Syn

      Article first published online: 29 JAN 2013 | DOI: 10.1002/hep.26270

      This article corrects:

      Hedgehog-responsive progenitors: Predictors of liver outcomes?‡

      Vol. 56, Issue 5, 2010–2011, Article first published online: 31 OCT 2012

  51. Autoimmune, Cholestatic and Biliary Disease

    1. Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus

      Oliver von Kampen, Stephan Buch, Michael Nothnagel, Lorena Azocar, Hector Molina, Mario Brosch, Wiebke Erhart, Witigo von Schönfels, Jan Egberts, Marcus Seeger, Alexander Arlt, Tobias Balschun, Andre Franke, Markus M. Lerch, Julia Mayerle, Wolfgang Kratzer, Bernhard O. Boehm, Klaus Huse, Bodo Schniewind, Katharina Tiemann, Zhao-Yan Jiang, Tian-Quan Han, Balraj Mittal, Anshika Srivastava, Mogens Fenger, Torben Jørgensen, Ramin Schirin-Sokhan, Anke Tönjes, Henning Wittenburg, Michael Stumvoll, Holger Kalthoff, Frank Lammert, Jürgen Tepel, Klaus Puschel, Thomas Becker, Stefan Schreiber, Matthias Platzer, Henry Völzke, Michael Krawczak, Juan Francisco Miquel, Clemens Schafmayer and Jochen Hampe

      Article first published online: 25 JAN 2013 | DOI: 10.1002/hep.26009

  52. Viral Hepatitis

    1. CD81/CD9 tetraspanins aid plasmacytoid dendritic cells in recognition of hepatitis C virus–infected cells and induction of interferon-alpha

      Shuye Zhang, Karen Kodys, Gregory J. Babcock and Gyongyi Szabo

      Article first published online: 18 JAN 2013 | DOI: 10.1002/hep.25827

  53. Hepatobiliary Malignancies

    1. Single determination of C-reactive protein at the time of diagnosis predicts long-term outcome of patients with hepatocellular carcinoma

      Wolfgang Sieghart, Matthias Pinter, Florian Hucke, Ivo Graziadei, Maximilian Schöniger-Hekele, Christian Müller, Wolfgang Vogel, Michael Trauner and Markus Peck-Radosavljevic

      Article first published online: 18 JAN 2013 | DOI: 10.1002/hep.26057

  54. Steatohepatitis/Metabolic Liver Disease

    1. Hepatic fat loss in advanced nonalcoholic steatohepatitis: Are alterations in serum adiponectin the cause?

      David van der Poorten, Caroline F. Samer, Mehdi Ramezani-Moghadam, Sally Coulter, Marina Kacevska, Dennis Schrijnders, Lindsay E. Wu, Duncan McLeod, Elisabetta Bugianesi, Mina Komuta, Tania Roskams, Christopher Liddle, Lionel Hebbard and Jacob George

      Article first published online: 18 JAN 2013 | DOI: 10.1002/hep.26072

  55. Autoimmune, Cholestatic and Biliary Disease

    1. Genome-wide association analysis in Primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4

      David Ellinghaus, Trine Folseraas, Kristian Holm, Eva Ellinghaus, Espen Melum, Tobias Balschun, Jon K. Laerdahl, Alexey Shiryaev, Daniel N. Gotthardt, Tobias J. Weismüller, Christoph Schramm, Michael Wittig, Annika Bergquist, Einar Björnsson, Hanns-Ulrich Marschall, Morten Vatn, Andreas Teufel, Christian Rust, Christian Gieger, H-Erich Wichmann, Heiko Runz, Martina Sterneck, Christian Rupp, Felix Braun, Rinse K. Weersma, Cisca Wijmenga, Cyriel Y. Ponsioen, Christopher G. Mathew, Paul Rutgeerts, Séverine Vermeire, Erik Schrumpf, Johannes R. Hov, Michael P. Manns, Kirsten M. Boberg, Stefan Schreiber, Andre Franke and Tom H. Karlsen

      Article first published online: 17 JAN 2013 | DOI: 10.1002/hep.25977

  56. Comments from the Editors

    1. Rare disease clinical research network's urea cycle consortium delivers a successful clinical trial to improve alternate pathway therapy

      Pramod K. Mistry

      Article first published online: 7 JAN 2013 | DOI: 10.1002/hep.26106

  57. Steatohepatitis/Metabolic Liver Disease

    1. Ammonia control and neurocognitive outcome among urea cycle disorder patients treated with glycerol phenylbutyrate

      George A. Diaz, Lauren S. Krivitzky, Masoud Mokhtarani, William Rhead, James Bartley, Annette Feigenbaum, Nicola Longo, William Berquist, Susan A. Berry, Renata Gallagher, Uta Lichter-Konecki, Dennis Bartholomew, Cary O. Harding, Stephen Cederbaum, Shawn E. McCandless, Wendy Smith, Gerald Vockley, Stephen A. Bart, Mark S. Korson, David Kronn, Roberto Zori, J. Lawrence Merritt II, Sandesh C.S. Nagamani, Joseph Mauney, Cynthia LeMons, Klara Dickinson, Tristen L. Moors, Dion F. Coakley, Bruce F. Scharschmidt and Brendan Lee

      Article first published online: 3 JAN 2013 | DOI: 10.1002/hep.26058

  58. Viral Hepatitis

    1. Causes of death in patients with hepatitis B: A natural history cohort study in the United States

      Jean-Luc Szpakowski and Lue-Yen Tucker

      Article first published online: 12 DEC 2012 | DOI: 10.1002/hep.26110

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