Arthritis & Rheumatism

© 2013 American College of Rheumatology

Cover image for Vol. 65 Issue 5

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: Joan M. Bathon, MD

Impact Factor: 7.866

ISI Journal Citation Reports © Ranking: 2011: 3/29 (Rheumatology)

Online ISSN: 1529-0131

Associated Title(s): Arthritis Care & Research

  1. Full Length

    1. Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation

      Hiroyuki Nakahara, Akihiko Hasegawa, Koji Otabe, Fumiaki Ayabe, Tetsuya Matsukawa, Naoko Onizuka, Yoshiaki Ito, Toshifumi Ozaki, Martin K. Lotz and Hiroshi Asahara

      Accepted manuscript online: 17 MAY 2013 01:55PM EST | DOI: 10.1002/art.38020

  2. Clinical Image

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      Hypercalcemia and miliary sarcoidosis in a 15 year-old male

      Holly K. Hodges, Pui Y. Lee, Jonathan S. Hausmann, Lisa A. Teot, Ethan L. Sanford and Kathleen W. Levin

      Accepted manuscript online: 17 MAY 2013 01:55PM EST | DOI: 10.1002/art.38019

  3. Letters to the Editor

    1. Rituximab in refractory and relapsed dermatomyositis and polymyositis: Comment on the article by Oddis et al

      Janet Cuttner, Harry Spiera and Peter Gorevic

      Accepted manuscript online: 17 MAY 2013 01:54PM EST | DOI: 10.1002/art.38018

  4. Full Length

    1. Anti-cyclic citrullinated peptide assays differ in subjects at elevated risk for rheumatoid arthritis and subjects with established disease

      M. Kristen Demoruelle, Mark C. Parish, Lezlie A. Derber, Jason R. Kolfenbach, Jan M. Hughes-Austin, Michael H. Weisman, William Gilliland, Jess D. Edison, Jane H. Buckner, Ted R. Mikuls, James R. O'Dell, Richard M. Keating, Peter K. Gregersen, Jill M. Norris, V. Michael Holers and Kevin D. Deane

      Accepted manuscript online: 17 MAY 2013 01:54PM EST | DOI: 10.1002/art.38017

    2. Sonographic joint assessment in rheumatoid arthritis: Associations with clinical joint assessment in remission

      Miriam Gärtner, Peter Mandl, Helga Radner, Gabriela Supp, Klaus P Machold, Daniel Aletaha and Josef S Smolen

      Accepted manuscript online: 17 MAY 2013 01:53PM EST | DOI: 10.1002/art.38016

    3. Premature cell senescence and T cell receptor-independent activation of CD8T cells in Juvenile Idiopathic Arthritis

      Jeffrey A. Dvergsten, Robert G. Mueller, Patricia Griffin, Sameem Abedin, Allyson Pishko, Joshua J. Michel, Margalit E. Rosenkranz, Ann M. Reed, Daniel A. Kietz and Abbe N. Vallejo

      Accepted manuscript online: 17 MAY 2013 01:52PM EST | DOI: 10.1002/art.38015

  5. Concise Communication

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      Long-term efficacy of adalimumab after drug withdrawal and retreatment of flare patients in active non-radiographic, axial spondyloarthritis

      H Haibel, F Heldmann, J Listing, H Kupper, J Braun and J Sieper

      Accepted manuscript online: 17 MAY 2013 01:52PM EST | DOI: 10.1002/art.38014

  6. Review Articles

    1. The preclinical phase of Rheumatoid Arthritis, what is acknowledged and what needs to be assessed?

      H.W. van Steenbergen, T.W.J. Huizinga and A.H.M. van der Helm-van Mil

      Accepted manuscript online: 17 MAY 2013 01:46PM EST | DOI: 10.1002/art.38013

  7. Full Length

    1. Validation of methotrexate-first strategy in early poor prognosis rheumatoid arthritis: Results from a randomized, double-blind, 2-year trial

      James R. O'Dell, Jeffrey R. Curtis, Ted Mikuls, Stacey Cofield, S. Louis Bridges Jr., Veena K. Ranganath and Larry W. Moreland, for the TEAR trial investigators

      Accepted manuscript online: 17 MAY 2013 01:41PM EST | DOI: 10.1002/art.38012

    2. Clinically insignificant effect of supplemental vitamin C on serum urate in patients with gout; A pilot randomised controlled trial

      Lisa K Stamp, John L O'Donnell, Christopher Frampton, Jill Drake, Mei Zhang and Peter T Chapman

      Accepted manuscript online: 16 MAY 2013 08:56AM EST | DOI: 10.1002/art.37925

  8. Editorials

    1. Entering the age of whole-exome sequencing in rheumatic diseases: Novel insights into disease pathogenicity

      Yukinori Okada and Robert M. Plenge

      Accepted manuscript online: 10 MAY 2013 02:15PM EST | DOI: 10.1002/art.38011

  9. Full Length

    1. Dnase1l3 mutations in hypocomplementemic urticarial vasculitis syndrome

      Z.Birsin Ozcakar, Joseph Foster II, Oscar Diaz-Horta, Ozgur Kasapcopur, Yao-Shan Fan, Fatos Yalcinkaya and Mustafa Tekin

      Accepted manuscript online: 10 MAY 2013 02:14PM EST | DOI: 10.1002/art.38010

    2. Brain morphometric changes associated with childhood-onset systemic lupus erythematosus and neurocognitive deficit

      Darren R. Gitelman, Marisa S. Klein-Gitelman, Jun Ying, Anna Carmela P. Sagcal-Gironella, Frank Zelko, Dean W. Beebe, Mark DiFrancesco, Todd Parrish, Jessica Hummel, Travis Beckwith and Hermine I. Brunner

      Accepted manuscript online: 10 MAY 2013 02:13PM EST | DOI: 10.1002/art.38009

    3. Protein kinase C δ deficiency causes mendelian systemic lupus erythematosus with B-cell defective apoptosis and hyperproliferation

      Alexandre Belot, Paul R. Kasher, Eleanor W. Trotter, Anne-Perrine Foray, Anne-Laure Debaud, Gillian I. Rice, Marcin Szynkiewicz, Marie-Therese Zabot, Isabelle Rouvet, Sanjeev S. Bhaskar, Sarah B. Daly, Jonathan E. Dickerson, Josephine Mayer, James O'Sullivan, Laurent Juillard, Jill E. Urquhart, Shameem Fawdar, Anna A. Marusiak, Natalie Stephenson, Bohdan Waszkowycz, Michael W. Beresford, Leslie G. Biesecker, Graeme M. Black, Céline René, Jean-François Eliaou, Nicole Fabien, Bruno Ranchin, Pierre Cochat, Patrick M. Gaffney, Flore Rozenberg, Pierre Lebon, Christophe Malcus, Yanick J. Crow, John Brognard and Nathalie Bonnefoy

      Accepted manuscript online: 10 MAY 2013 02:12PM EST | DOI: 10.1002/art.38008

    4. Interleukin-7 enhances Th1 response to promote the development of Sjögren's Syndrome-Like autoimmune exocrinopathy

      Jun-O Jin, Toshihisa Kawai, Seunghee Cha and Qing Yu

      Accepted manuscript online: 10 MAY 2013 02:12PM EST | DOI: 10.1002/art.38007

  10. Clinical Image

    1. Vascular malformation as a cause of limp in a child

      Abdulrahman Al-Rasheed, Marilyn Ranson and Ronald M. Laxer

      Accepted manuscript online: 10 MAY 2013 02:10PM EST | DOI: 10.1002/art.38005

  11. Letters to the Editor

    1. Dual role of CpG-stimulated B cells in the regulation of dendritic cells

      Mohan S Maddur, Srini V Kaveri and Jagadeesh Bayry

      Accepted manuscript online: 10 MAY 2013 02:10PM EST | DOI: 10.1002/art.38004

  12. Reply to Letters to the Editor

    1. Dual role of CpG-stimulated B cells in the regulation of dendritic cells (ar-13-0366) by Maddur Mohan et al.

      Maija-Leena Eloranta and Lars Rönnblom

      Accepted manuscript online: 10 MAY 2013 02:06PM EST | DOI: 10.1002/art.38003

  13. Editorials

    1. Interleukin-7 and its receptor: The axis of evil to target in Sjögren's syndrome?

      Joel A.G van Roon, Aike A. Kruize and Timothy R. D.J. Radstake

      Accepted manuscript online: 10 MAY 2013 02:06PM EST | DOI: 10.1002/art.38002

  14. Full Length

    1. HLA-B27 alters the response to TNFα and promotes osteoclastogenesis in bone marrow monocytes from HLA-B27 transgenic rats

      Gerlinde Layh-Schmitt, Eva Y. Yang, Grace Kwon and Robert A. Colbert

      Accepted manuscript online: 10 MAY 2013 02:05PM EST | DOI: 10.1002/art.38001

    2. Hsp90 inhibition protect against biomechanically-induced osteoarthritis

      Michiel Siebelt, Holger Jahr, Harald C. Groen, Marjan Sandker, Jan H. Waarsing, Nicole Kops, Cristina Müller, Willem van Eden, Marion de Jong and Harrie Weinans

      Accepted manuscript online: 10 MAY 2013 02:05PM EST | DOI: 10.1002/art.38000

  15. Letters to the Editor

    1. IgG4-related pharyngitis-an addition to the nomenclature of IgG4-related disease: Comment on the article by Stone et al.

      Gita Fatemi and Meika A. Fang

      Accepted manuscript online: 10 MAY 2013 02:04PM EST | DOI: 10.1002/art.37999

  16. Reply to Letter to the Editor

    1. Reply: IgG4-related pharyngitis

      Mollie N. Carruthers, Eli Miloslavsky and John H. Stone

      Accepted manuscript online: 10 MAY 2013 02:01PM EST | DOI: 10.1002/art.37998

  17. Full Length

    1. Osteoprotegerin causes apoptosis of endothelial progenitor cells by induction of oxidative stress

      Ji-Young Kim, Yune-Jung Park, Ki-Jo Kim, Jin-Jung Choi, Wan-Uk Kim and Chul-Soo Cho

      Accepted manuscript online: 10 MAY 2013 02:01PM EST | DOI: 10.1002/art.37997

    2. Infrapatellar fat pad of OA patients stimulates fibrotic processes in cultured synoviocytes; a possible role for Prostaglandin F2α

      Yvonne M Bastiaansen-Jenniskens, Wu Wei, Carola Feijt, Jan H Waarsing, Jan AN Verhaar, Anne-Marie Zuurmond, Roeland Hanemaaijer, Reinout Stoop and Gerjo JVM van Osch

      Accepted manuscript online: 10 MAY 2013 02:00PM EST | DOI: 10.1002/art.37996

    3. Angiogenesis in rheumatoid arthritis is directly fostered by TLR5 ligation and indirectly through IL-17 induction

      Seung-jae Kim, Zhenlong Chen, Nathan D. Chamberlain, Michael V. Volin, William Swedler, Suncica Volkov, Nadera Sweiss and Shiva Shahrara

      Accepted manuscript online: 10 MAY 2013 01:58PM EST | DOI: 10.1002/art.37992

    4. Lysophosphatidic acid receptor LPA1 is essential for development of arthritis

      Yoshishige Miyabe, Chie Miyabe, Yoshiko Iwai, Aiko Takayasu, Shin Fukuda, Waka Yokoyama, Jun Nagai, Masahiro Jona, Yasunori Tokuhara, Ryunosuke Ohkawa, Harald M. Albers, Huib Ovaa, Junken Aoki, Jerold Chun, Yutaka Yatomi, Hiroshi Ueda, Masayuki Miyasaka, Nobuyuki Miyasaka and Toshihiro Nanki

      Accepted manuscript online: 10 MAY 2013 01:57PM EST | DOI: 10.1002/art.37991

  18. Review Articles

    1. The role of microRNAs in osteoarthritis and chondrogenesis

      LinhT T Le, Tracey E Swingler and Ian M Clark

      Accepted manuscript online: 10 MAY 2013 01:57PM EST | DOI: 10.1002/art.37990

  19. Full Length

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      Sphingosine-1-phosphate counteracts interleukin-1β in human chondrocytes

      Martin H. Stradner, Gerald Gruber, Hannes Angerer, Verena Huber, Daniela Setznagl, Marie-Luise Kremser, Florentine C. Fürst, Reinhard Windhager and Winfried B. Graninger

      Accepted manuscript online: 10 MAY 2013 01:57PM EST | DOI: 10.1002/art.37989

  20. Review Articles

    1. Systemic sclerosis (scleroderma, SSc) is a vascular disease

      Marco Matucci-Cerinic, Bashar Kahaleh and Fredrick M. Wigley

      Accepted manuscript online: 10 MAY 2013 01:55PM EST | DOI: 10.1002/art.37988

  21. Full Length

    1. Acute vibration induces transient expression of anabolic genes in the intervertebral disc in a frequency-dependent manner

      Matthew R. McCann, Priya Patel, Kim L. Beaucage, Yizhi Xiao, Corey Bacher, Walter L. Siqueira, David W. Holdsworth, S. Jeffrey Dixon and Cheryle A. Séguin

      Accepted manuscript online: 9 MAY 2013 02:22PM EST | DOI: 10.1002/art.37979

  22. Brief Reports

    1. Ultraviolet radiation exposure is associated with clinical and autoantibody phenotypes in Juvenile Myositis

      Mona Shah, Ira N. Targoff, Madeline M. Rice, Frederick W. Miller and Lisa G. Rider, with the Childhood Myositis Heterogeneity Collaborative Study Group

      Accepted manuscript online: 8 MAY 2013 10:42PM EST | DOI: 10.1002/art.37985

  23. Full Length

    1. Transcriptome analysis of human injured meniscus reveals a distinct phenotype of meniscus degeneration with aging

      Muhammad Farooq Rai, Debabrata Patra, Linda J. Sandell and Robert H. Brophy

      Accepted manuscript online: 8 MAY 2013 10:42PM EST | DOI: 10.1002/art.37984

    2. Differentially expressed epigenome modifiers, including Aurora kinase A and B, in immune cells of rheumatoid arthritis

      Tibor T. Glant, Timea Besenyei, András Kádár, Júlia Kurkó, Beata Tryniszewska, János Gál, Györgyi Soós, Zoltán Szekanecz, Gyula Hoffmann, Joel A. Block, Robert S. Katz, Katalin Mikecz and Tibor A. Rauch

      Accepted manuscript online: 8 MAY 2013 04:55AM EST | DOI: 10.1002/art.37986

  24. Clinical Image

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      Ancient schwannoma

      Clarissa Canella, Flavia Costa, Evandro Klumb, Ierecê Lins Aymoré and Edson Marchiori

      Accepted manuscript online: 8 MAY 2013 04:55AM EST | DOI: 10.1002/art.37983

  25. Full Length

    1. MRI-based three-dimensional bone shape of the knee predicts onset of knee osteoarthritis: Data from the Osteoarthritis Initiative

      Tuhina Neogi, Michael Bowes, Jingbo Niu, Kevin De Souza, Graham Vincent, Joyce Goggins, Yuqing Zhang and David T. Felson

      Accepted manuscript online: 3 MAY 2013 10:27AM EST | DOI: 10.1002/art.37987

    2. Evidence for CXCL16 as a potent angiogenic mediator and endothelial progenitor cell chemotactic factor

      Takeo Isozaki, Ali S. Arbab, Christian S. Haas, M. Asif Amin, Monica D. Arendt, Alisa E. Koch and Jeffrey H. Ruth

      Accepted manuscript online: 30 APR 2013 10:32AM EST | DOI: 10.1002/art.37981

  26. Letters to the Editor

    1. The historical concept of interrelated conditions lumped together as a family of distinct diseases is not outdated

      Henning Zeidler

      Accepted manuscript online: 18 APR 2013 10:45AM EST | DOI: 10.1002/art.37980

  27. Clinical Image

    1. Ischemic reaction secondary to corticosteroid joint injection

      Shirley Tse, Dax Rumsey, Michael Temple and Gregory Borschel

      Accepted manuscript online: 18 APR 2013 09:04AM EST | DOI: 10.1002/art.37978

  28. Full Length

    1. Glucosamine activates autophagy in vitro and in vivo

      Beatriz Caramés, William B. Kiosses, Yukio Akasaki, Diana C. Brinson, William Eap, James Koziol and Martin K. Lotz

      Accepted manuscript online: 18 APR 2013 09:04AM EST | DOI: 10.1002/art.37977

  29. Brief ReportS

    1. High throughput sequencing of IL23R reveals a low-frequency non-synonymous SNP that is associated with Ankylosing spondylitis in a Han Chinese population

      Stuart I. Davidson, Lei Jiang, Adrian Cortes, Xin Wu, Evgeny A. Glazov, Marina Donskoi, Yi Zheng, Patrick A. Danoy, Yi Liu, Gethin P. Thomas, Matthew A. Brown and Huji Xu

      Accepted manuscript online: 18 APR 2013 09:03AM EST | DOI: 10.1002/art.37976

  30. Editorial

    1. Data support evidence-based management recommendations for cardiovascular disease in rheumatoid arthritis

      William Dixon

      Accepted manuscript online: 18 APR 2013 09:02AM EST | DOI: 10.1002/art.37975

  31. Editorials

    1. Cardiovascular disease management in RA

      M.J.L. Peters and Michael Nurmohamed

      Accepted manuscript online: 18 APR 2013 09:02AM EST | DOI: 10.1002/art.37974

  32. Clinical Image

    1. Mobile vertebral fluid collection associated with compression fracture

      Seok Won Kim and Hyun-Sook Kim

      Accepted manuscript online: 18 APR 2013 09:02AM EST | DOI: 10.1002/art.37973

  33. Full Length

    1. Subchondral bone trabecular integrity predicts and changes concurrently with radiographic and MRI determined knee osteoarthritis progression

      Virginia Byers Kraus, Sheng Feng, ShengChu Wang, Scott White, Maureen Ainslie, Marie-Pierre Hellio Le Graverand, Alan Brett, Felix Eckstein, David J Hunter, Nancy E Lane, Mihra S. Taljanovic, Thomas Schnitzer and H Cecil Charles

      Accepted manuscript online: 10 APR 2013 01:51PM EST | DOI: 10.1002/art.37970

    2. Cancer incidence in systemic sclerosis: Meta-analysis of population-based cohort studies

      Akira Onishi, Daisuke Sugiyama, Shunichi Kumagai and Akio Morinobu

      Accepted manuscript online: 10 APR 2013 01:51PM EST | DOI: 10.1002/art.37969

    3. C-reactive protein inhibits plasmacytoid dendritic cell interferon responses to autoantibody immune complexes

      Carolyn Mold and Terry W. Du Clos

      Accepted manuscript online: 10 APR 2013 01:51PM EST | DOI: 10.1002/art.37968

    4. Diet influences expression of autoimmune associated genes and disease severity by epigenetic mechanisms in a transgenic lupus model

      Faith M. Strickland, Anura Hewagama, Ailing Wu, Amr H. Sawalha, Colin Delaney, Mark F. Hoeltzel, Raymond Yung, Kent Johnson, Barbara Mickelson and Bruce C. Richardson

      Accepted manuscript online: 10 APR 2013 01:51PM EST | DOI: 10.1002/art.37967

    5. Glucocorticoids suppress T cell function by upregulating microRNA 98

      Trevor E Davis, Katalin Kis-Toth, Attila Szanto and George C. Tsokos

      Accepted manuscript online: 10 APR 2013 01:51PM EST | DOI: 10.1002/art.37966

    6. Class I HDAC inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation

      Kirsty L Culley, Wang Hui, Matt J Barter, Rose K Davidson, Tracey E Swingler, Auriane P M Destrument, Jenny L. Scott, Simon T Donell, Steve Fenwick, Andrew D Rowan, David A Young and Ian M Clark

      Accepted manuscript online: 10 APR 2013 01:51PM EST | DOI: 10.1002/art.37965

    7. Auto-antibodies to post translationally modified type II collagen as potential biomarkers for rheumatoid arthritis

      Rocky Strollo, Frederique Ponchel, Vivianne Malmström, Paola Rizzo, Michele Bombardieri, Claire Y Wenham, Rebecca Landy, David Perret, Fiona Watt, Valerie M Corrigall, Paul G Winyard, Paolo Pozzilli, Philip G Conaghan, Gabriel S Panayi, Lars Klareskog, Paul Emery and Ahuva Nissim

      Accepted manuscript online: 10 APR 2013 01:50PM EST | DOI: 10.1002/art.37964

    8. Overexpression of SIRT6 suppresses inflammatory responses and bone destruction in collagen-induced arthritic mice

      Hwa-Suk Lee, Sun-O Ka, Sang-Myeong Lee, Sang-Il Lee, Jin-Woo Park and Byung-Hyun Park

      Accepted manuscript online: 1 APR 2013 02:23PM EST | DOI: 10.1002/art.37963

    9. Neuropathic features of joint pain: A community-based study

      A Soni, RN Batra, SE Gwilym, TD Spector, DJ Hart, NK Arden, C Cooper, I Tracey and MK Javaid

      Accepted manuscript online: 1 APR 2013 02:22PM EST | DOI: 10.1002/art.37962

  34. Brief Report

    1. Citrullination within the atherosclerotic plaque: A potential target for the anti-citrullinated protein antibody response in rheumatoid arthritis

      Jeremy Sokolove, Orr Sharpe, Matthew Brennan, Lauren J. Lahey, Amy H. Kao, Eswar Krishnan, Daniel Edmundowicz, Christin M. Lepus, Mary Chester Wasko and William H. Robinson

      Accepted manuscript online: 1 APR 2013 02:22PM EST | DOI: 10.1002/art.37961

  35. Full Length

    1. Long-term detection of human adipose derived mesenchymal stem cells after intra-articular injection

      Karine Toupet, Marie Maumus, Julie-Anne Peyrafitte, Philippe Bourin, Peter van Lent, Rosanna Ferreira, Béatrice Orsetti, Nelly Pirot, Louis Casteilla, Christian Jorgensen and Danièle Noël

      Accepted manuscript online: 1 APR 2013 02:22PM EST | DOI: 10.1002/art.37960

    2. ANCA-associated vasculitis patients have defective Treg function exacerbated by presence of a suppression-resistant effector population

      Meghan E Free, Donna O Bunch, JulieAnne McGregor, Britta E Jones, Elisabeth A Berg, Susan L Hogan, Yichun Hu, Gloria A Preston, J. Charles Jennette, Ronald J Falk and Maureen A Su

      Accepted manuscript online: 1 APR 2013 02:22PM EST | DOI: 10.1002/art.37959

    3. Interferon-γ mediates anemia but is dispensable for fulminant toll-like receptor 9-induced macrophage activation syndrome and hemophagocytosis

      Scott W. Canna, Julia Wrobel, Niansheng Chu, Portia A. Kreiger, Michele Paessler and Edward M. Behrens

      Accepted manuscript online: 1 APR 2013 02:22PM EST | DOI: 10.1002/art.37958

    4. Soluble receptor for advanced glycation end products alleviates nephritis in NZB/WF1 mice

      Sang-Won Lee, Kyu-Hyung Park, Sungha Park, Ji-Hye Kim, Sung-Yu Hong, Soo-Kon Lee, Donghoon Choi and Yong-Beom Park

      Accepted manuscript online: 1 APR 2013 12:26PM EST | DOI: 10.1002/art.37955

    5. Assessing subclinical synovitis in rheumatoid arthritis

      Matthias Witt, Felix Mueller, Axel Nigg, Christiane Reindl, Jan Leipe, Fabian Proft, Nicola Stein, Ariane Hammitzsch, Stefan Mayer, Claudia Dechant, Hendrik Schulze-Koops and Mathias Grunke

      Accepted manuscript online: 1 APR 2013 12:26PM EST | DOI: 10.1002/art.37954

    6. Vitamin D in SLE: Modest association with disease activity and urine protein/creatinine ratio

      Michelle Petri, Kayode J. Bello, Hong Fang and Laurence S. Magder

      Accepted manuscript online: 1 APR 2013 12:26PM EST | DOI: 10.1002/art.37953

  36. Clinical Image

    1. Inquiry is fatal to certainty: Is the US double contour sign specific for uric acid arthritis?

      Antonella Adinolfi, Valentina Picerno, Valentina Di Sabatino, Ilaria Bertoldi, Mauro Galeazzi, Bruno Frediani and Georgios Filippou

      Accepted manuscript online: 1 APR 2013 12:26PM EST | DOI: 10.1002/art.37952

  37. Full Length

    1. Identification of soluble 14-3-3ε as a new subchondral bone mediator involved in cartilage degradation in osteoarthritis

      Sabrina Priam, Carole Bougault, Xavier Houard, Marjolaine Gosset, Colette Salvat, Francis Berenbaum and Claire Jacques

      Accepted manuscript online: 1 APR 2013 12:26PM EST | DOI: 10.1002/art.37951

    2. Tanezumab reduces osteoarthritic hip pain: Results of a randomized, double-blind, placebo-controlled phase 3 trial

      Mark T. Brown, Frederick T. Murphy, David M. Radin, Isabelle Davignon, Michael D. Smith and Christine R. West

      Accepted manuscript online: 1 APR 2013 12:26PM EST | DOI: 10.1002/art.37950

  38. Brief Reports

    1. Rheumatoid arthritis is associated with left ventricular concentric remodeling: Results of a population-based cross-sectional study

      Elena Myasoedova, John M. Davis, Cynthia S. Crowson, Véronique L. Roger, Barry L. Karon, Daniel D. Borgeson, Terry M. Therneau, Eric L. Matteson, Richard J. Rodeheffer and Sherine E. Gabriel

      Accepted manuscript online: 1 APR 2013 12:25PM EST | DOI: 10.1002/art.37949

  39. Full Length

    1. MicroRNA miR-29a protects from glucocorticoid-induced bone loss and fragility by orchestrating bone acquisition and resorption

      Feng-Sheng Wang, Chung Pei-Chin, Chung-Liang Lin, Ming-Wen Chen, Huei-Jin Ke, Yu-Hsuan Chang, Yu-Shan Chen, Shin-Long Wu and Jih-Yang Ko

      Accepted manuscript online: 25 MAR 2013 11:48AM EST | DOI: 10.1002/art.37948

    2. Meniscus body position, size and shape in persons with and without radiographic knee osteoarthritis: Quantitative analyses of knee MRIs from the Osteoarthritis Initiative

      Andrea Wenger, Wolfgang Wirth, Martin Hudelmaier, Iris Noebauer-Huhmann, Siegfried Trattnig, Katja Bloecker, Richard B. Frobell, Kent Kwoh, Felix Eckstein and Martin Englund

      Accepted manuscript online: 25 MAR 2013 11:48AM EST | DOI: 10.1002/art.37947

  40. Letters to the Editor

    1. Inhibition of indoleamine 2,3-dioxygenase does not block only autoreactive B-cell activation, but reduces antibodies production in general

      Theodoros Eleftheriadis, Georgios Pissas, Vassilios Liakopoulos and Ioannis Stefanidis

      Accepted manuscript online: 25 MAR 2013 11:48AM EST | DOI: 10.1002/art.37946

    2. Is it the time to adopt salivary gland ultrasonography as an alternative diagnostic tool for the classification of patients with Sjögren's syndrome?

      Claudio Vitali, Marina Carotti and Fausto Salaffi

      Accepted manuscript online: 25 MAR 2013 11:48AM EST | DOI: 10.1002/art.37945

  41. Reply to Letters to the Editor

    1. Contribution of salivary gland ultrasonography to the diagnosis of Sjögren's syndrome: Towards new diagnostic criteria?

      Divi Cornec, Sandrine Jousse-Joulin, Alain Saraux and Valérie Devauchelle-Pensec

      Accepted manuscript online: 25 MAR 2013 11:48AM EST | DOI: 10.1002/art.37944

  42. Brief Reports

    1. Testosterone is protective in the sexually dimorphic development of arthritis and lung disease in SKG mice

      Rebecca C. Keith, Jeremy Sokolove, Benjamin L. Edelman, Lauren Lahey, Elizabeth F. Redente, V. Michael Holers, Shimon Sakaguchi, William H. Robinson and David W.H. Riches

      Accepted manuscript online: 25 MAR 2013 11:47AM EST | DOI: 10.1002/art.37943

  43. Concise Communications

    1. New evidence supports a role of MiR-140 at early stages of bone development

      Francisco Esteban Nicolas and Tamas Dalmay

      Accepted manuscript online: 25 MAR 2013 11:47AM EST | DOI: 10.1002/art.37941

  44. Full Length

    1. Comparison of alternative primary outcome measures for use in a lupus nephritis trial

      David Wofsy, Jan L. Hillson and Betty Diamond

      Accepted manuscript online: 25 MAR 2013 11:47AM EST | DOI: 10.1002/art.37940

  45. Brief Reports

    1. Reduced joint counts misclassify psoriatic arthritis patients with oligoarthritis and miss significant active disease

      Laura C Coates, Oliver FitzGerald, Dafna D Gladman, Neil McHugh, Philip Mease, Vibeke Strand and Philip S Helliwell, on behalf of the GRACE collaboration

      Accepted manuscript online: 25 MAR 2013 11:46AM EST | DOI: 10.1002/art.37939

  46. Full Length

    1. Association of variants in IL2RA with progression of joint destruction in Rheumatoid Arthritis

      R. Knevel, D.P.C. de Rooy, A. Zhernakova, G. Gröndal, A. Krabben, K. Steinsson, C. Wijmenga, G. Cavet, R.E.M. Toes, T.W.J. Huizinga, P.K. Gregersen and A.H.M. van der Helm-van Mil

      Accepted manuscript online: 25 MAR 2013 11:42AM EST | DOI: 10.1002/art.37938

    2. In situ analysis of IL-23 and IL-12 positive cells in the spine of patients with ankylosing spondylitis

      Heiner Appel, Rene Maier, Janine Bleil, Axel Hempfing, Christoph Loddenkemper, Uwe Schlichting, Uta Syrbe and Joachim Sieper

      Accepted manuscript online: 18 MAR 2013 12:30PM EST | DOI: 10.1002/art.37937

    3. Combinatorial control of Th17 and Th1 cell function by genetic variation at genes associated with the IL-23 signaling pathway in spondyloarthritis

      Maryaline Coffre, Mathilde Roumier, Magda Rybczynska, Emmanuel Sechet, Helen K.W. Law, Laure Gossec, Maxime Dougados, Elisabetta Bianchi and Lars Rogge

      Accepted manuscript online: 18 MAR 2013 12:30PM EST | DOI: 10.1002/art.37936

    4. Familial Mediterranean fever in heterozygotes: Are we able to accurately diagnose the disease in very young children?

      Véronique Hentgen, Gilles Grateau, Katia Stankovic-Stojanovic, Serge Amselem and Isabelle Jeru

      Accepted manuscript online: 18 MAR 2013 12:29PM EST | DOI: 10.1002/art.37935

    5. Enhanced ROCK activation in patients with systemic lupus erythematosus

      Josephine Isgro, Sanjay Gupta, Elzbieta Jacek, Tanya Pavri, Roland Duculan, Mimi Kim, Kyriakos A. Kirou, Jane E. Salmon and Alessandra B. Pernis

      Accepted manuscript online: 18 MAR 2013 12:29PM EST | DOI: 10.1002/art.37934

    6. FTY720 ameliorates murine Scl-cGVHD by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin

      Doanh Le Huu, Takashi Matsushita, Guihua Jin, Yasuhito Hamaguchi, Minoru Hasegawa, Kazuhiko Takehara and Manabu Fujimoto

      Accepted manuscript online: 18 MAR 2013 12:29PM EST | DOI: 10.1002/art.37933

    7. A MMP1-cleavable composite peptide derived from βig-h3 potently inhibits chronic inflammatory arthritis

      Eon Jeong Nam, Jin Hee Kang, Shijin Sung, Keum Hee Sa, Kyung Hoon Kim, Jae Seok Seo, Jong-Ho Kim, Seung Woo Han, In San Kim and Young Mo Kang

      Accepted manuscript online: 18 MAR 2013 12:29PM EST | DOI: 10.1002/art.37932

  47. Letter to the Editor

    1. Commentary on the article “Mortality rates in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors. Drug-specific comparisons in the Swedish Biologics Register”

      Guillaume Moulis, Agnès Sommet and Maryse Lapeyre-Mestre

      Accepted manuscript online: 18 MAR 2013 12:27PM EST | DOI: 10.1002/art.37931

    2. Neoplasms as the leading cause of mortality among TNF alpha inhibitor users with rheumatoid arthritis? Comment on the article by Simard et al.

      Hasan Yazici, Koray Tascilar and Yusuf Yazici

      Accepted manuscript online: 18 MAR 2013 12:27PM EST | DOI: 10.1002/art.37930

  48. Reply to Letter to the Editor

    1. Reply

      Julia F Simard, Martin Neovius and Johan Askling

      Accepted manuscript online: 18 MAR 2013 12:27PM EST | DOI: 10.1002/art.37929

  49. Editorials

    1. Bone and osteoarthritis: What is the relationship?

      MK Javaid and NK Arden

      Accepted manuscript online: 12 MAR 2013 12:23PM EST | DOI: 10.1002/art.37924

  50. Full Length

    1. Relationship of bone mineral density to progression of knee osteoarthritis

      Ji Y. Lee, William F. Harvey, Lori L. Price, Jessica K. Paulus, Bess Dawson-Hughes and Timothy E. McAlindon

      Accepted manuscript online: 12 MAR 2013 12:22PM EST | DOI: 10.1002/art.37926

    2. TNFR1 expression of CD4+ T cells in rheumatoid arthritis enables them to follow TNF gradients into the rheumatoid synovium

      Manuela Rossol, Kristin Schubert, Undine Meusch, Anett Schulz, Bernd Biedermann, Jens Grosche, Matthias Pierer, Roger Scholz, Christoph Baerwald, Andreas Thiel, Sebastian Hagen and Ulf Wagner

      Accepted manuscript online: 12 MAR 2013 12:22PM EST | DOI: 10.1002/art.37927

    3. Rheumatoid arthritis in Latin Americans enriched for Amerindian ancestry is associated with loci in chromosomes 1, 12,13, and HLA class II region

      David López Herráez, Manuel Martínez-Bueno, Laura Riba, Ignacio García de la Torre, Mónica Sacnún, Mario Goñi, Guillermo Berbotto, Sergio Paira, Jorge Luis Musuruana, César Graf, Alejandro Alvarellos, Osvaldo D. Messina, Alejandra Babini, Ingrid Strusberg, Juan Carlos Marcos, Hugo Scherbarth, Alberto Spindler, Ana Quinteros, Sergio Toloza, José Luis C. Moreno, Luis J. Catoggio, Guillermo Tate, Alicia Eimon, Gustavo Citera, Antonio Catalán Pellet, Gustavo Nasswetter, Mario H. Cardiel, Pedro Miranda, Francisco Ballesteros, Jorge A. Esquivel-Valerio, Marco A.Maradiaga-Ceceña, Eduardo M. Acevedo-Vásquez, Conrado García García, Teresa Tusié-Luna, Bernardo Pons-Estel and Marta E. Alarcón-Riquelme

      Accepted manuscript online: 4 MAR 2013 02:26PM EST | DOI: 10.1002/art.37923

    4. Rac1 is required for matrix metalloproteinase-13 production by chondrocytes in response to fibronectin fragments

      David L. Long, Jeffrey S. Willey and Richard F. Loeser

      Accepted manuscript online: 4 MAR 2013 02:26PM EST | DOI: 10.1002/art.37922

    5. Metabolic profiling predicts response to anti-TNFα therapy in patients with rheumatoid arthritis

      Sabrina R. Kapoor, Andrew Filer, Martin A Fitzpatrick, Benjamin A. Fisher, Peter C. Taylor, Christopher D Buckley, Iain B McInnes, Karim Raza and Stephen P. Young

      Accepted manuscript online: 4 MAR 2013 02:26PM EST | DOI: 10.1002/art.37921

    6. Neuropathic pain in ankylosing spondylitis - a psychophysics and brain imaging study

      Qi Wu, Robert D. Inman and Karen D. Davis

      Accepted manuscript online: 4 MAR 2013 02:26PM EST | DOI: 10.1002/art.37920

    7. Changes in lipoproteins associated with treatment with methotrexate or combination therapy in early rheumatoid arthritis: Results from the TEAR trial

      Iris Navarro-Millán, Christina Charles-Schoeman, Shuo Yang, Joan M. Bathon, S. Louis Bridges Jr, Lang Chen, Stacey S Cofield, Louis J. Dell'Italia, Larry W Moreland, James R. O'Dell, Harold E. Paulus and Jeffrey R Curtis

      Accepted manuscript online: 4 MAR 2013 02:25PM EST | DOI: 10.1002/art.37916

  51. Clinical Image

    1. Osteoblastoma of the ilium mimicking sacroiliitis

      Kourosh Modaressi, Bruno Fuchs PhD, Peter Bode, Reto Sutter, Severin Meili and Ulrich Weber

      Accepted manuscript online: 4 MAR 2013 02:25PM EST | DOI: 10.1002/art.37915

  52. Full Length

    1. Toll-like receptor 2 is required for autoantibody production and development of renal disease in pristane-induced lupus

      Vilma Urbonaviciute, Charlotte Starke, Wiebke Pirschel, Sandy Pohle, Silke Frey, Christoph Daniel, Kerstin Amann, Georg Schett, Martin Herrmann and Reinhard E. Voll

      Accepted manuscript online: 28 FEB 2013 01:32PM EST | DOI: 10.1002/art.37914

  53. Brief Reports

    1. Susceptibility to childhood onset rheumatoid arthritis: Investigation of a weighted genetic risk score that integrates cumulative effects of variants at five genetic loci

      Sampath Prahalad, Karen N. Conneely, Yunxuan Jiang, Marc Sudman, Carol A. Wallace, Milton R. Brown, Lori A. Ponder, Mina Rohani-Pichavant, Michael E. Zwick, David J. Cutler, Sheila T. Angeles-Han, Larry B. Vogler, Christine Kennedy, Kelly Rouster-Stevens, Carol A. Wise, Marilynn Punaro, Ann M. Reed, Elizabeth D. Mellins, John F. Bohnsack, David N. Glass and Susan D. Thompson

      Accepted manuscript online: 28 FEB 2013 01:32PM EST | DOI: 10.1002/art.37913

  54. Full Length

    1. MicroRNA-30a promotes B cell hyperactivity in patient with SLE by direct interaction with LYN

      Yu Liu, Jie Dong, Rong Mu, Yaping Gao, Xiaorong Tan, Yuhui Li, Zhanguo Li and Guang Yang

      Accepted manuscript online: 28 FEB 2013 01:32PM EST | DOI: 10.1002/art.37912

    2. Anti-citrullinated protein antibodies (ACPA) in unaffected first degree relatives of rheumatoid arthritis patients

      Lillian Barra, Mathias Scinocca, Sheri Saunders, Rajesh Bhayana, Sherry Rohekar, Maud Racapé, Robert Coles, Ewa Cairns and David A. Bell

      Accepted manuscript online: 28 FEB 2013 01:32PM EST | DOI: 10.1002/art.37911

    3. Dysregulation of CD4+CD25hi+ T cells in the synovial fluid of patients with antibiotic-refractory Lyme arthritis

      Nalini K. Vudattu, Klemen Strle, Allen C. Steere and Elise E. Drouin

      Accepted manuscript online: 28 FEB 2013 01:32PM EST | DOI: 10.1002/art.37910

  55. Review Articles

    1. A&R special issue: Disease mechanisms in rheumatology: Tools and pathways

      Laurent Chiche, Noemie Jourde-Chiche, Virginia Pascual and Damien Chaussabel

      Accepted manuscript online: 28 FEB 2013 01:32PM EST | DOI: 10.1002/art.37909

  56. Full Length

    1. In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae

      Frank C. Ko, Cecilia Dragomir, Darren A. Plumb, Steven R. Goldring, Timothy M. Wright, Mary B. Goldring and Marjolein C.H. van der Meulen

      Accepted manuscript online: 22 FEB 2013 10:41AM EST | DOI: 10.1002/art.37906

  57. Letters to the Editor

    1. Frequency of antibodies to mutated-citrullinated vimentin in chronic obstructive pulmonary disease: Comment on the article by Demoruelle et al.

      Maria Chiara Gerardi, Nicoletta De Luca, Cristiano Alessandri, Cristina Iannuccelli, Guido Valesini and Manuela Di Franco

      Accepted manuscript online: 22 FEB 2013 10:41AM EST | DOI: 10.1002/art.37905

  58. Reply to Letters to the Editor

    1. Reply to Geradi and colleagues regarding RA-related autoantibodies and lung disease

      M. Kristen Demoruelle and Kevin D. Deane

      Accepted manuscript online: 22 FEB 2013 10:41AM EST | DOI: 10.1002/art.37904

  59. Full Length

    1. Inhibition of connective tissue growth factor ameliorates rheumatoid arthritis in a murine model

      Kazuhisa Nozawa, Maki Fujishiro, Mikiko Kawasaki, Ayako Yamaguchi, Keigo Ikeda, Shinji Morimoto, Kazuhisa Iwabuchi, Mitsuaki Yanagida, Shouzo Ichinose, Megumi Morioka, Hideoki Ogawa, Kenji Takamori, Yoshinari Takasaki and Iwao Sekigawa

      Accepted manuscript online: 22 FEB 2013 10:41AM EST | DOI: 10.1002/art.37902

    2. Transcriptomics of wild type and mice lacking ADAMTS-5 activity identifies genes involved in osteoarthritis initiation and cartilage destruction

      John F. Bateman, Lynn Rowley, Daniele Belluoccio, Ben Chan, Katrina Bell, Amanda J. Fosang and Christopher B. Little

      Accepted manuscript online: 22 FEB 2013 10:41AM EST | DOI: 10.1002/art.37900

    3. A hot spot for systemic lupus erythematosus but not for psoriatic arthritis identified by spatial analysis suggests an interaction between race and place of residence

      Mustafa Al-Maini, Thurarshen Jeyalingam, Patrick Brown, Jennifer J.Y. Lee, Lennon Li, Jiandong Su, Dafna D.Gladman and Paul R. Fortin

      Accepted manuscript online: 11 FEB 2013 03:21PM EST | DOI: 10.1002/art.37897

  60. Special

    1. Independent development of inflammation and new bone formation in ankylosing spondylitis

      Georg Schett

      Accepted manuscript online: 21 FEB 2012 03:43PM EST | DOI: 10.1002/art.34441

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