Birth Defects Research Part A: Clinical and Molecular Teratology

Cover image for Vol. 100 Issue 9

Edited By: Michel Vekemans

Impact Factor: 2.211

ISI Journal Citation Reports © Ranking: 2013: 27/41 (Developmental Biology); 48/87 (Toxicology)

Online ISSN: 1542-0760

Associated Title(s): Birth Defects Research Part B: Developmental and Reproductive Toxicology, Birth Defects Research Part C: Embryo Today: Reviews

Featured

  • Immortal time bias in observational studies of drug effects in pregnancy

    Immortal time bias in observational studies of drug effects in pregnancy

    Immortal time bias during the third trimester of pregnancy. A time-fixed analysis will misclassify the unexposed time between the start of the trimester to the prescribing of a decongestant as exposed. This time is also immortal because it is not possible, by design, for a preterm delivery to occur during this time period. Any preterm delivery occurring before exposure to decongestants would necessarily be classified as unexposed events. Immortal time bias can be avoided using the appropriate time-varying analyses that correctly classify exposure during follow-up.

  • Fetal alcohol syndrome surveillance: Age of syndrome manifestation in case ascertainment

    Fetal alcohol syndrome surveillance: Age of syndrome manifestation in case ascertainment

    Age in months at ascertaining abstraction, confirmed and probable cases of fetal alcohol syndrome.

  • Further evidence suggesting a role for variation in ARHGAP29 variants in nonsyndromic cleft lip/palate

    Further evidence suggesting a role for variation in ARHGAP29 variants in nonsyndromic cleft lip/palate

    Schematic representation of the ARHGAP29 gene structure and linkage disequilibrium plot. A: Gene structure of ARHGAP29 with colored bars representing exons, horizontal lines representing introns. Arrows denote location of genotyped SNPs. B: Linkage disequilibrium plot with boxes representing the marker pair relationship plotted between two markers. The color of the boxes (intensity of the color) is based on the raw score for that marker pair. Squares are colored darker if the D′ value is high (i.e., LD is strong), lighter shades indicate less LD. Empty dark squares mean D′ = 1 (i.e., complete LD between two SNPs). [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]

  • Hirschsprung's disease prevalence in Europe: A register based study

    Hirschsprung's disease prevalence in Europe: A register based study

    Total prevalence of Hirschsprung's disease by register.

  • Dermatan sulfate epimerase 1 deficient mice as a model for human abdominal wall defects

    Dermatan sulfate epimerase 1 deficient mice as a model for human abdominal wall defects

    Expression of the epidermal layer markers in WT, Dse Het, and KO epidermis. A: Immunohistochemical staining of transversally sectioned newborn tails from WT, Dse Het and Dse KO mice for loricrin, keratin1 and keratin 5 (green) and Dapi (blue). Note enhanced keratin 1 staining in the spinous layer and keratin 5 staining in the basal layer in Dse KO epidermis compared with WT and Dse Het epidermis (n=3 for each genotype). Dotted line denotes the dermo–epidermal border. Abbreviations: Gr, granular layer; Sp, spinous layer; B, basal layer; D, dermis. (Scale bars = 50 µm). B: Densitometric analysis and representative western blot images of keratin 5 on whole body skin extracts from newborn WT, Dse Het and Dse KO mice (n = 3 for each genotype). There was a 1.6-fold increase in keratin 5 expression in Dse KO skin compared with WT skin. Gapdh was used as internal loading control. Gel images were analyzed in ImageJ program, and statistical differences were calculated by one-way ANOVA. AU, arbitrary units. Error bars are SEM.

  • Birth prevalence and survival of exomphalos in england and wales: 2005 to 2011

    Birth prevalence and survival of exomphalos in england and wales: 2005 to 2011

    Birth prevalence of exomphalos in 18 European countries: 2005 to 2011. Note: UK includes the same registers as in this study. Data from EUROCAT prevalence tables http://www.eurocatnetwork.eu/accessprevalencedata/prevalencetables, data uploaded 12/12/2013.

  • Immortal time bias in observational studies of drug effects in pregnancy
  • Fetal alcohol syndrome surveillance: Age of syndrome manifestation in case ascertainment
  • Further evidence suggesting a role for variation in ARHGAP29 variants in nonsyndromic cleft lip/palate
  • Hirschsprung's disease prevalence in Europe: A register based study
  • Dermatan sulfate epimerase 1 deficient mice as a model for human abdominal wall defects
  • Birth prevalence and survival of exomphalos in england and wales: 2005 to 2011

Recently Published Issues

See all

  • Current Issue:September 2014

    Volume 100, Issue 9

  • August 2014

    Volume 100, Issue 8

    Special Issue: NTD Special Issue

  • July 2014

    Volume 100, Issue 7

    Special Issue: Abstracts from the 2nd Internationa...

  • June 2014

    Volume 100, Issue 6

  • May 2014

    Volume 100, Issue 5

    Special Issue: 54th Annual Teratology Society Meet...

Special Issue: Abstracts from the 2nd International Joined OTIS - ENTIS Conference

NA

Open Access Articles in BDRA: Clinical and Molecular Teratology

Click below to read this OnlineOpen content in BDRA: Clinical and Molecular Teratology for FREE:

Corticosteroid use and risk of orofacial clefts
Hildur Skuladottir, Allen J. Wilcox, Chen Ma, Edward J. Lammer, Sonja A. Rasmussen, Martha M. Werler, Gary M. Shaw, Suzan L. Carmichael
Volume 100, Issue 6, June 2014

Nuclear factor-kappa-B signaling in lung development and disease: One pathway, numerous functions
Cristina M. Alvira
Volume 100, Issue 3, March 2014

Sex prevalence of major congentical anomalies in the United Kingdom: A national population-based study and international comparison meta-analysis
Rachel Sokal, Laila J. Tata, Kate M. Fleming
Volume 100, Issue 2, February 2014

Knowledge and periconceptual use of folic acid for the prevention of neural tube defects in ethnic communities in the United Kingdom: Systematic review and meta-analysis
Jordana N. Peake, Andrew J. Copp, Jill Shawe
Volume 97, Issue 7, July 2013

Announcements

5 Year Impact Factor announced: 2.666!

Birth Defects Research Distinguished Scholar AwardsCongratulations to Dr. Bengt Källen, the winner of the Birth Defects Research Distinguished Scholar Award for his paper in Birth Defects Research: Part A: In vitro fertilization (IVF) in Sweden: Risk for congenital malformations after different IVF methods. Details of the Award can be read here.

Now in EarlyView

Now Available Online:

Prevention of orofacial clefts caused by smoking: Implications of the Surgeon General's report
Margaret A. Honein, Owen Devine, Scott D. Grosse and Jennita Reefhuis

Immortal time bias in observational studies of drug effects in pregnancy
Ilan Matok, Laurent Azoulay, Hui Yin and Samy Suissa

Mitochondrial one-carbon metabolism and neural tube defects
Jessica Momb and Dean R. Appling

Limb-body wall defect: Experience of a reference service of fetal medicine from Southern Brazil
Sibele Nascimento de Aquino, Ryuichi Hoshi, Elizabete Bagordakis, Maria Giulia Rezende Pucciarelli, Ana Camila Messetti, Helenara Moreira, Andreia Bufalino, Andréa Borges, Ana Lucia Rangel, Luciano Abreu Brito, Mario Sergio Oliveira Swerts, Hercilio Martelli-Junior, Sergio R. Line, Edgard Graner, Sílvia R.A. Reis, Maria Rita Passos-Bueno and Ricardo D. Coletta

Population-based study to determine mortality in spina bifida: New York State congenital malformations registry, 1983 to 2006
Vijaya Kancherla, Charlotte M. Druschel and Godfrey P. Oakley Jr.


SEARCH

SEARCH BY CITATION