Birth Defects Research Part B: Developmental and Reproductive Toxicology

Cover image for Vol. 104 Issue 4

Edited By: George P. Daston

Impact Factor: 0.768

ISI Journal Citation Reports © Ranking: 2014: 82/87 (Toxicology); 154/167 (Genetics & Heredity); 198/211 (Oncology)

Online ISSN: 1542-9741

Associated Title(s): Birth Defects Research Part A: Clinical and Molecular Teratology, Birth Defects Research Part C: Embryo Today: Reviews, Teratogenesis, Carcinogenesis, and Mutagenesis

Featured

  • Time Course for Onset and Recovery from Effects of a Novel Male Reproductive Toxicant: Implications for Apical Preclinical Study Designs

    Time Course for Onset and Recovery from Effects of a Novel Male Reproductive Toxicant: Implications for Apical Preclinical Study Designs

    Number of live fetuses: study B.

  • An Enhanced Pre- and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody

    An Enhanced Pre‐ and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody
  • An Enhanced Pre- and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody

    An Enhanced Pre‐ and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody

    Mean maternal B-lymphocyte count relative to control (A); mean maternal B-lymphocyte count relative to pretreatment values (B); mean infant B-lymphocyte count decrease relative to control (C); and mean infant relative B-lymphocyte percentages relative to control (D). *Significantly different from control, p ≤ 0.05. N = 9 to 14 per group for adults and 7 to 11 per group for infants.

  • Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody

    Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody

    Body weight of female rabbits during gestation in an embryo–fetal development study.

  • Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody

    Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody

    Body weight of female rabbits in a fertility study.

  • Agent Orange Exposure and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) in Human Milk

    Agent Orange Exposure and 2,3,7,8‐Tetrachlorodibenzo‐p‐Dioxin (TCDD) in Human Milk

    Infant tissue concentration distribution for TCDD by feeding method. Closed symbols, adipose tissue; open symbols, liver. Horizontal bars are means. Distributions for each tissue are significantly different between feeding method (Mann-Whitney U-test performed by current author). Drawn from data presented by Kreuzer et al. ().

  • Time Course for Onset and Recovery from Effects of a Novel Male Reproductive Toxicant: Implications for Apical Preclinical Study Designs
  • An Enhanced Pre‐ and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody
  • An Enhanced Pre‐ and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody
  • Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody
  • Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody
  • Agent Orange Exposure and 2,3,7,8‐Tetrachlorodibenzo‐p‐Dioxin (TCDD) in Human Milk

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Open Access Articles in BDRB: Developmental and Reproductive Toxicology

Click below to read these OnlineOpen Articles in BDRB: Developmental and Reproductive Toxicology for FREE:

Developmental Toxicity Studies with Atrazine and its Major Metabolites in Rats and Rabitts
Anthony R. Scialli, John M. DeSesson, Charles B. Breckenridge

Atrazine and Pregnancy Outcomes: A Systematic Review of Epidemiologic Evidence
Michael Goodman, Jack S. Mandel, John M. DeSesso

Effects of Ethylene Glyocol Monomethyl Ether and Its Metabolite, 2-Methoxyacetic Acid, on Organogenesis Stage Mouse Limbs in Vitro
Caroline Dayan, Barbara F. Hales

The Effect of Atrazine Administered by Gavage or in Diet on the LH Surge and Reproductive Performance in Intact Female Sprague-Dawley and Long Evans Rats
Chad D. Foradori, Prägati Sawhney Coder, Merrill Tisdel, Kun Don Yi, James W. Simpkins, Robert J. Handa and Charles B. Breckenridge

Top Downloaded Articles

Check out these top downloaded articles FREE for a limited time!

NTP-CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A
Chapin, R. E., Adams, J., Boekelheide, K., Gray, L. E., Hayward, S. W., Lees, P. S.J., McIntyre, B. S., Portier, K. M., Schnorr, T. M., Selevan, S. G., Vandenbergh, J. G. and Woskie, S. R.

Evaluation of the reproductive and developmental risks of caffeine
Brent, R. L., Christian, M. S. and Diener, R. M.

Interpreting Estrogen Screening Assays in the Context of Potency and Human Exposure Relative to Natural Exposures to Phytoestrogens
Becker, R. A., Hays, S. M., Kirman, C. R., Aylward, L. L. and Wise, K.

Considerations in assessing the developmental and reproductive toxicity potential of biopharmaceuticals
Martin, P. L., Breslin, W., Rocca, M., Wright, D. and Cavagnaro, J

Key Learnings from Performance of the U.S. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 In Vitro Assays
LeBaron, M. J., Coady, K. K., O'Connor, J. C., Nabb, D. L., Markell, L. K., Snajdr, S. and Sue Marty, M

Birth Defects Research Distinguished Scholar Awards

Birth Defects Research Distinguished Scholar AwardsCongratulations to Dr. Karen A. Augustine-Rauch and Dr. Kimberly Brannen, recipients of the 2015 Birth Defects Research Distinguished Scholar Award for their research associated with development of a zebrafish embryo teratogenicity assay and the associated quantitative prediction model published in Birth Defects Research: Part B: Development of a zebrafish embryo teratogenicity assay and quantitative predictive model.

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