Pediatric Blood & Cancer

Cover image for Vol. 65 Issue 4

Edited By: Editor-in-Chief: Peter E. Newburger, M.D. | Deputy Editor: Thomas Gross, M.D., Ph.D.

Impact Factor: 2.513

ISI Journal Citation Reports © Ranking: 2016: 26/121 (Pediatrics); 36/70 (Hematology); 134/217 (Oncology)

Online ISSN: 1545-5017

Featured Cover Images

  • Volume 65, Issue 4 Cover Image

    Volume 65, Issue 4 Cover Image

    The cover figure is from Figure 3 in Girón-Vallejo, et al. “Three-dimensional printed model of bilateral Wilms tumor: A useful tool for planning nephron sparing surgery”. 3D reconstruction of right kidney from magnetic resonance imaging.

  • Volume 65, Issue 3 Cover Image

    Volume 65, Issue 3 Cover Image

    The cover figure is from Figure 1 in Rathe et al. “Successful management of transfusion-dependent congenital dyserythropoietic anemia type 1b with interferon alfa-2a”. (A) Touch imprint of bone marrow biopsy shows erythroid precursors with prominent dyserythropoietic features including megaloblastic changes, binuclearity and basophilic stipling, and interchromatin bridging (May-Grünwald-Giemsa, 630×). (B) Cranial MRI showing strong thickening of the cranial bones and widening of the diploic space in a child with congenital dyserythropoietic anemia type 1b due to hypertrophy of the red bone marrow caused by anemia. The basic structure of the bone is not affected, but there is deformation of the bones and skull cap

  • Volume 65, Issue 2 Cover Image

    Volume 65, Issue 2 Cover Image

    The cover figure is from Figure 2 in Hord et al. “The American Society of Pediatric Hematology/Oncology workforce assessment: Part 1—Current state of the workforce”. American Board of Pediatrics pediatric hematology–oncology physician distribution throughout the United States in 2015. Note: The number of diplomates includes only specialists under the age of 66 with known addresses as of 12/31/2015. Adapted, with permission, from American Board of Pediatrics Inc.

  • Volume 65, Issue 1 Cover Image

    Volume 65, Issue 1 Cover Image

    The cover figure is from Figure 1 in Kramer, et al. “A phase II study of radioimmunotherapy with intraventricular 131 I-3F8 for medulloblastoma”. Whole body images of a fused MRI and PET scan following intraventricular injection of radiolabeled antibody (3F8) showing activity (A) in the ventricles and (B) in the subdural space, and spinal canal via sagittal images.

  • Volume 64, Issue 12 Cover Image

    Volume 64, Issue 12 Cover Image

    The cover figure is from Figure 1 in Hirabayashi, et al. “Constitutional abnormalities of IDH1 combined with secondarymutations predispose a patient with Maffucci syndrometo acute lymphoblastic leukemia”. Hypothetical model of the pathogenesis of hemangioma, enchondroma, and ALL. HSC, hematopoietic stem cell; MSC, mesenchymal stem cell; mut, mutation; del, deletion.

  • Volume 64, Issue 11 Cover Image

    Volume 64, Issue 11 Cover Image

    The cover figure is from Figure 1 in Jacobson, et al. "Refractory cytopenias secondary to copper deficiency in children receiving exclusive jejunal nutrition." Panel A, B & C show photomicrographs taken from Giemsa stained bone marrow aspirate smear showing myeloid & erythroid left shift with small cytoplasmic and nuclear vacuoles seen in myeloid and erythroid precursors. Note the increased number of early hematopoietic progenitor cells (arrow heads) that mimic blasts. Panel D shows abnormal ring sideroblasts (arrows) in an iron stained aspirate smear (Case 2).

  • Volume 64, Issue 10 Cover Image

    Volume 64, Issue 10 Cover Image

    The cover figure is Figure 1 in El Madi, et al. Operative view of a transmanubrial osteomuscular-sparing approach showing the vascular and nerves structures dissected. BCV, brachiocephalic vein; CA, carotid artery; JV, jugular vein; PN, phrenic nerve; SA, subclavian artery; SV, subclavian vein; TM, tumor; VA, vertebral artery; VN, vagus nerve.

  • Volume 64, Issue 9 Cover Image

    Volume 64, Issue 9 Cover Image

    The cover figure is from Figure 5 in Bleyer, et al. Average Percent Change from 1990 to 2010 in the 5-Year Relative Survival of All Invasive Cancer by 5-Year Age Intervals (vertical bars) and Proportion of All Invasive Cancer in Adolescent and Young Adult (AYA) Patient 15 to 39 Years of Age and in Younger and Older Age Groups (horizontal arrows), United States SEER 9-18 Regions. Kaposi sarcoma and non-Hodgkin lymphoma in males has been excluded because of the HIV/AIDS epidemic that included the early years of the era evaluated. The data demonstrate that, as recently as 2010, 15 to 29 year-olds have had the least progress in survival prolongation among all age groups with cancer below 70 years of age, and that 20 to 24 year-olds have had virtually no improvement during 1990-2010.

  • Volume 64, Issue 8 Cover Image

    Volume 64, Issue 8 Cover Image

    The cover figure is from Figure 1 in Iwai, et al. Sagittal plane of dose distribution in craniospinal irradiation using hair-sparing whole brain irradiation with volumetric-modulated arc therapy.

  • Volume 64, Issue 7 Cover Image

    Volume 64, Issue 7 Cover Image

    The cover figure is from Figure 1 in Siddaiahgari, et al. Pre-op MRI demonstrating a primary intracranial choriocarcinoma as a heterogenous mass lesion in the posterior third ventricle with moderate heterogeneous enhancement post contrast.

  • Volume 64, Issue 6 Cover Image

    Volume 64, Issue 6 Cover Image

    The cover figure is from Figure 2 in Bruzek, et al. Proposed Targeted Inhibitors of the Ras-MAPK Pathway. Neurofibromin loss-of-function and FGFR1 activation in a pediatric spinal oligodendroglioma are the two identified potential drivers of oncogenesis, and inhibitors of either pathway are attractive targeted therapy agents. Upstream inhibition of the Ras-MAPK pathway at the level of FGFR1 can be achieved with the tyrosine kinase inhibitor, ponatinib. Downstream inhibition of the Ras-MAPK pathway can be achieved with the MEK inhibitor, trametinib.

  • Volume 64, Issue 5 Cover Image

    Volume 64, Issue 5 Cover Image

    The cover figure is from Figure 1 in Syed, et al. Renal cancers by age from 1973-2013 for overall SEER cohort (N=3,670).

  • Volume 64, Issue 4 Cover Image

    Volume 64, Issue 4 Cover Image

    The cover figure is from Figure 1 in Skalska-Sadowska, et al. Cytogenetic analysis of bone marrow cells at diagnosis of T-ALL in a 4-year-old male. Interphase nuclei with one normal signal (yellow) and split signal red (5’MYC) and green (3’MYC) from MYC break-apart probe.

  • Volume 64, Issue 3 Cover Image

    Volume 64, Issue 3 Cover Image

    The cover figure is from Figure 2 in Mody, et al. Molecular data in precision oncology. Pediatric cancers may harbor clinically relevant germline and somatic variants, copy number aberrations, gene fusions, and gene expression patterns. Here, the outer circle indicates the type of molecular event. The middle circle indicates the various molecular assays used to profile a given molecular event. The inner circle provides several examples of clinically-relevant findings enabled by molecular profiling. WES: whole exome sequencing. WGS: whole genome sequencing. cDNA: complementary DNA. Mut: mutation. Amp: amplification. Del: deletion. Indel: Insertion/deletion. SNV: single nucleotide variant. aCGH: array comparative genome hybridization.

  • Volume 65, Issue 4 Cover Image
  • Volume 65, Issue 3 Cover Image
  • Volume 65, Issue 2 Cover Image
  • Volume 65, Issue 1 Cover Image
  • Volume 64, Issue 12 Cover Image
  • Volume 64, Issue 11 Cover Image
  • Volume 64, Issue 10 Cover Image
  • Volume 64, Issue 9 Cover Image
  • Volume 64, Issue 8 Cover Image
  • Volume 64, Issue 7 Cover Image
  • Volume 64, Issue 6 Cover Image
  • Volume 64, Issue 5 Cover Image
  • Volume 64, Issue 4 Cover Image
  • Volume 64, Issue 3 Cover Image

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Journal News

Pediatric Blood & Cancer Special Series

New Section!

The journal is pleased to announce a new submission type—On Children, Blood, and Cancer. These submissions will provide personal perspectives on the experiences of children with cancer or blood disorders, or of caring for these children. The section will be led by Dr. David N. Korones, of the University of Rochester. For more information, visit our Author Guidelines page.

Standards for Psychosocial Care for Children With Cancer and Their Families

This Special Issue is dedicated to the memory of Robert J. Arceci, M.D., Ph.D. Dr. Arceci, an internationally prominent pediatric oncologist and the former editor of this Journal, was, throughout his life, committed to a biopsychosocial approach and to advancing the behavioral health of children with cancer and their families. While working tirelessly to cure pediatric cancer, he also strongly believed that children and families deserve effective psychosocial care to alleviate suffering until cures without costs emerge. Dr. Arceci championed publication of the Standards for the Psychosocial Care of Children with Cancer and their Families in this Pediatric Blood and Cancer Special Issue until his death on June 8, 2015. We are grateful for and will miss his passionate enthusiasm, his support and his friendship.

Publication of this supplement is made possible by the Mattie Miracle Foundation.

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Click here to view a webinar for more information

2017 Congress of the Paediatric Radiation Oncology, New York, 22-24 June. The congress will be attended by radiation oncologists worldwide involved in treating children with cancer, as well as physicians in training, nurses, radiation therapists, physicists and dosimetrists. The aims of the congress are to exchange knowledge, to promote research and education, and to assist participants from developing countries in the selection and proper use of radiation technologies, as well as the training of personnel. The abstract Deadline has been extended to 10 March. Please visit our website (www.intpros.org) for information and registration.

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