Journal of Biomedical Materials Research Part A

Cover image for Vol. 103 Issue 10

Edited By: James M. Anderson

Impact Factor: 3.369

ISI Journal Citation Reports © Ranking: 2014: 13/76 (Engineering Biomedical); 16/33 (Materials Science Biomaterials)

Online ISSN: 1552-4965

Associated Title(s): Journal of Biomedical Materials Research Part B: Applied Biomaterials

Featured

  • Chitosan selectively promotes adhesion of myoblasts over fibroblasts

    Chitosan selectively promotes adhesion of myoblasts over fibroblasts

    Actin network of myoblasts on chitosan-coated plates and on uncoated plates at depth closest to adherent surface. Scale bars represent 5 μm. The arrows indicate F-actin filaments spreading away from the nucleus in myoblasts in chitosan-coated plates. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]

  • The effect of extracellular matrix proteins on the cellular response of HUVECS and HOBS after covalent immobilization onto titanium

          The effect of extracellular matrix proteins on the cellular response of HUVECS and HOBS after covalent immobilization onto titanium

    Immobilization procedure of the ECM proteins fibronectin, collagen, osteopontin, and laminin. (1) Plasma polymerization of allylamine (pp-AA), (2) cross-linking using α, ω-bis-N-hydroxysuccinimide polyethylene glycol, (3) Immobilization of the ECM proteins.

  • Nano-textured fluidic biochip as biological filter for selective survival of neuronal cells

    Nano‐textured fluidic biochip as biological filter for selective survival of neuronal cells

    Two-photon fluorescence cross-section image of (a) SiNTs with water on it and (b) SiNTs with Rhodamine B aqueous solution on it. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]

  • Influence of the nanostructure of F-doped TiO2 films on osteoblast growth and function

    Influence of the nanostructure of F‐doped TiO2 films on osteoblast growth and function

    MCT3T3-E1 cell proliferation (measured by Alamar Blue assay) at days 2 and 7 (a); matrix mineralization at day 10 of culture (b); and gene expression of osteoblastic (Runx2 and OC) and angiogenic (VEGF) markers (c), at day 5, in the presence of Ti-6Al-4V (CP) and Ti-6Al-4V with various anodic oxide films, F-free (BL) and F-containing (FBL, NP, NT). SEMs were less than 1% in all of the experimental conditions. Results are mean ± SEM (n = 4). *p < 0.01 versus CP; **p < 0.0001 versus CP. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]

  • Osteocalcin/fibronectin-functionalized collagen matrices for bone tissue engineering

    Osteocalcin/fibronectin‐functionalized collagen matrices for bone tissue engineering

    Schematic representation of collagen matrices. Collagen cross-linked by EDC with rhOCN/FNIII9-10 or rhFNIII9-10 (100 μg/mL). [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]

  • Boron nitride nanotubes chemically functionalized with glycol chitosan for gene transfection in eukaryotic cell lines

    Boron nitride nanotubes chemically functionalized with glycol chitosan for gene transfection in eukaryotic cell lines

    Transfection assay for pIRES plasmid in A549 cell line. (a and b) Negative control, without nanoparticle or Effectene; (c and d) Positive control using Effectene reagent; (e and f) 10 µg/mL BNNT-1 carrying the pIRES plasmid; (g and h) 10 µg/mL BNNT-2 carrying the pIRES plasmid; (a, c, e, g) presents the bright field images and (b, d, f, h) presents the fluorescent images. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]

  • Physiological osmolarities do not enhance long-term tissue synthesis in chondrocyte-laden degradable poly(ethylene glycol) hydrogels

    Physiological osmolarities do not enhance long‐term tissue synthesis in chondrocyte‐laden degradable poly(ethylene glycol) hydrogels

    A: Viability of encapsulated chondrocytes 1 day after encapsulation in degrading hydrogels cultured in the presence of different medium osmolarities and osmolytes. Live cells fluoresce green, dead cells fluoresce red. Scale bars indicate 200 μm. Representative images shown are from one donor (images were similar for the other two donors). B: DNA per wet weight as a function of medium osmolarity and osmolyte and culture time. Day 1 indicates 24 h postencapsulation. Data represent the mean and standard deviation of n = 3 donors. *Indicates significant difference from 330 mOsm, and †indicates significant difference from 400 mOsm (sucrose) at specified time point (p < 0.05). C: Representative week 4 immunohistochemical images of constructs containing chondrocytes isolated from one donor (images were similar for the other two donors), stained for aggrecan (red), collagen I, II, and X (green), and C1,2C collagen fragments (green). Sections were counterstained with DAPI (blue) for cell nuclei. Scale bars represent 200 μm, inset image scale bars are 50 μm. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]

  • Chitosan selectively promotes adhesion of myoblasts over fibroblasts
  •       The effect of extracellular matrix proteins on the cellular response of HUVECS and HOBS after covalent immobilization onto titanium
  • Nano‐textured fluidic biochip as biological filter for selective survival of neuronal cells
  • Influence of the nanostructure of F‐doped TiO2 films on osteoblast growth and function
  • Osteocalcin/fibronectin‐functionalized collagen matrices for bone tissue engineering
  • Boron nitride nanotubes chemically functionalized with glycol chitosan for gene transfection in eukaryotic cell lines
  • Physiological osmolarities do not enhance long‐term tissue synthesis in chondrocyte‐laden degradable poly(ethylene glycol) hydrogels

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