Journal of Biomedical Materials Research Part A

Cover image for Vol. 106 Issue 2

Edited By: James M. Anderson

Impact Factor: 3.076

ISI Journal Citation Reports © Ranking: 2016: 17/33 (Materials Science Biomaterials); 21/77 (Engineering Biomedical)

Online ISSN: 1552-4965

Associated Title(s): Journal of Biomedical Materials Research Part B: Applied Biomaterials

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  • Synthesis and bioactivity assessment of high silica content quaternary glasses with Ca: P ratios of 1.5 and 1.67, made by a rapid sol-gel process

    Synthesis and bioactivity assessment of high silica content quaternary glasses with Ca: P ratios of 1.5 and 1.67, made by a rapid sol‐gel process

    SEM images for 1.50 and 1.67 glass powders before and after immersion in SBF for different time periods under stirring at 120 rpm.

  • Construction of human induced pluripotent stem cell-derived oriented bone matrix microstructure by using in vitro engineered anisotropic culture model

    Construction of human induced pluripotent stem cell‐derived oriented bone matrix microstructure by using in vitro engineered anisotropic culture model

    Undifferentiated human induced pluripotent stem cells (hiPSCs). Phase-contrast images of hiPSC colonies (A) immediately after seeding and (B) after 4 days of culturing on SNL feeder cells. Immunocytochemical images of hiPSC colonies stained for (C) SSEA-4 (green) and (D) alkaline phosphatase (red). Blue, nuclei. Scale bars, 100 μm.

  • Pressure responsive nanogel base on Alginate-Cyclodextrin with enhanced apoptosis mechanism for colon cancer delivery

    Pressure responsive nanogel base on Alginate‐Cyclodextrin with enhanced apoptosis mechanism for colon cancer delivery

    FE-SEM images of Al-CD nanoparticles.

  • Local delivery of strontium ranelate promotes regeneration of critical size bone defects filled with collagen sponge

    Local delivery of strontium ranelate promotes regeneration of critical size bone defects filled with collagen sponge

    Photomicrographs of rat calvaria defects filled with collagen sponge alone (group C: A and D) and soaked with 5 mM Sr2+ strontium ranelate (group C5SR: B and E) or 50 mM Sr2+ strontium ranelate (group C50SR: C and F) after 6 weeks, analyzed by polarization light microscopy. In C group, calvaria defect filled with a thin layer of collagen fibers from connective tissue (A) and bone receptor bed are showing reddish birefringence (A and D). In C5SR (B and E) and C50SR (C and F) groups, the newly formed bone exhibits thicker layers of collagen showing green/yellowish birefringence. Staining: Picrosirius red. Magnification: A-C = 16×, D-F = 100×.

  • Surface modification of ultrahigh molecular weight polyethylene by plasma-induced in-situ grafting with vinyl triethoxysilane

    Surface modification of ultrahigh molecular weight polyethylene by plasma‐induced in‐situ grafting with vinyl triethoxysilane

    Fluorescence coloration results of the cells cultured on different sample surfaces and the blank control, (a) for the blank control, (b) for virgin UHMWPE, (c) for PT-UHMWPE, and (d) for PT-UHMWPE/VTEOS. The numbers 1, 2, and 3 mean the culture time of 1, 2, and 3 days, respectively. The scale bar in the embedded image = 20 μm and the one in the large image = 100 μm.

  • Bone-healing capacity of conditioned medium derived from three-dimensionally cultivated human mesenchymal stem cells and electrical stimulation on collagen sponge

    Bone‐healing capacity of conditioned medium derived from three‐dimensionally cultivated human mesenchymal stem cells and electrical stimulation on collagen sponge

    Bone-healing effects of CM on inflammatory cytokine-induced bone loss. Inflammatory bone loss of the mouse calvaria was induced by IL-1 loaded on collagen disks. (A) Schematic outline of experimental design. Five days after IL-1 (1 μg/disk) of implantation, CM-CON, CM-ES concentrate or hMSC (5 × 105 cells) were subcutaneously injected into the calvaria skin where the collagen disks were positioned. After 14 days, the calvaria were removed and analyzed using micro-CT. (B) 3D micro-CT images of calvaria 14 days after sacrifice are presented. (C) BV (mm3), (D) Tb.N (1/mm), (E)Tb.Th, and (F) Tb.Sp of newly ossified tissue are expressed as mean ± SD. Significant differences between two groups: *p < 0.05 and **p < 0.01.

  • Synthesis and bioactivity assessment of high silica content quaternary glasses with Ca: P ratios of 1.5 and 1.67, made by a rapid sol‐gel process
  • Construction of human induced pluripotent stem cell‐derived oriented bone matrix microstructure by using in vitro engineered anisotropic culture model
  • Pressure responsive nanogel base on Alginate‐Cyclodextrin with enhanced apoptosis mechanism for colon cancer delivery
  • Local delivery of strontium ranelate promotes regeneration of critical size bone defects filled with collagen sponge
  • Surface modification of ultrahigh molecular weight polyethylene by plasma‐induced in‐situ grafting with vinyl triethoxysilane
  • Bone‐healing capacity of conditioned medium derived from three‐dimensionally cultivated human mesenchymal stem cells and electrical stimulation on collagen sponge

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