Journal of Biomedical Materials Research Part A

Cover image for Vol. 106 Issue 3

Edited By: James M. Anderson

Impact Factor: 3.076

ISI Journal Citation Reports © Ranking: 2016: 17/33 (Materials Science Biomaterials); 21/77 (Engineering Biomedical)

Online ISSN: 1552-4965

Associated Title(s): Journal of Biomedical Materials Research Part B: Applied Biomaterials

Featured

  • Time course study of long-term biocompatibility and foreign body reaction to intraneural polyimide-based implants

    Time course study of long‐term biocompatibility and foreign body reaction to intraneural polyimide‐based implants

    Cellular events in the tissue capsule around the device. Representative confocal images of cells in the capsule from 1 day to 32 weeks. Macrophages (red) are in contact with the device until 16 weeks. Fibroblasts (green) appear at 4–8 weeks and are located in the periphery of the capsule, in contact with nerve fibers. Scale bar = 15 µm.

  • Atomic force microscopy and nanoindentation investigation of polydimethylsiloxane elastomeric substrate compliancy for various sputtered thin film morphologies

    Atomic force microscopy and nanoindentation investigation of polydimethylsiloxane elastomeric substrate compliancy for various sputtered thin film morphologies

    3D surface scans with scan lines of nichrome thin film over PDMS surface showing nichrome hillocks of increasing height for deposition time of (a) 2 min and (b) 15 min, respectively; AFM images of cracks over PDMS surface after nichrome removal showing PDMS hills for deposition time of (c) 2 min and (d) 15 min, respectively, and their corresponding scan lines.

  • Hydrogel/fiber conductive scaffold for bone tissue engineering

    Hydrogel/fiber conductive scaffold for bone tissue engineering

    Cross-sectional SEM images of hydrogel (A&B) and hydrogel/fiber composite (C,D). Magnification: ×750 for (A,C) and ×1.2 K for (B,D).

  • Functionalizing titanium surface with PAMAM dendrimer and human BMP2 gene via layer-by-layer assembly for enhanced osteogenesis

    Functionalizing titanium surface with PAMAM dendrimer and human BMP2 gene via layer‐by‐layer assembly for enhanced osteogenesis

    Immunohistochemical staining of femora tissues peri-implant. The expression of GFP, BMP-2, OPN, and OCN of bone tissue around different Ti implants were also detected by immunohistochemical staining in different groups 4 weeks after implantation, scale bar = 200 μm.

  • Effect of decellularized spinal scaffolds on spinal axon regeneration in rats

    Effect of decellularized spinal scaffolds on spinal axon regeneration in rats

    The components of collagens and cytokines DC spinal cord scaffold. Immunofluorescence analysis shows that expression of collagens I (A), III (B), and IV (C), Fibronectin (D), FGF (E), and VEGF (F) are present in the extracellular matrix of DC spinal scaffold. Scar bars = 50 μm.

  • Hydrostatic pressure in combination with topographical cues affects the fate of bone marrow-derived human mesenchymal stem cells for bone tissue regeneration

    Hydrostatic pressure in combination with topographical cues affects the fate of bone marrow‐derived human mesenchymal stem cells for bone tissue regeneration

    hBMSC orientation on PCL fibers and chemical characterization of mechanically stimulated nanofibers. After being cultured on fiber well plates for 21 days and subjected to cyclic hydrostatic pressure cells followed fiber orientation (cells are indicated by white arrows). a’–d’: SEM images were taken for random and (e’–h’) aligned fibers at (a’, e’) 100×, (f’) 500×, (g’) 3000×, (c’) 4000×, (b’, h’) 10,000×, and (d’) 20,000× magnification. Scale bars = 300, 60, 10, 7.5, 3, and 1.5 µm, respectively. EDX analysis confirmed the presence of Ca, P, and O on (a–d, i) random and (e–h, j) aligned mechanically stimulated fibers. EDX images were taken at 4000x magnification and scale bar = 9 µm.

  • Time course study of long‐term biocompatibility and foreign body reaction to intraneural polyimide‐based implants
  • Atomic force microscopy and nanoindentation investigation of polydimethylsiloxane elastomeric substrate compliancy for various sputtered thin film morphologies
  • Hydrogel/fiber conductive scaffold for bone tissue engineering
  • Functionalizing titanium surface with PAMAM dendrimer and human BMP2 gene via layer‐by‐layer assembly for enhanced osteogenesis
  • Effect of decellularized spinal scaffolds on spinal axon regeneration in rats
  • Hydrostatic pressure in combination with topographical cues affects the fate of bone marrow‐derived human mesenchymal stem cells for bone tissue regeneration

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