Journal of Biomedical Materials Research Part A

Cover image for Vol. 105 Issue 10

Edited By: James M. Anderson

Impact Factor: 3.076

ISI Journal Citation Reports © Ranking: 2016: 17/33 (Materials Science Biomaterials); 21/77 (Engineering Biomedical)

Online ISSN: 1552-4965

Associated Title(s): Journal of Biomedical Materials Research Part B: Applied Biomaterials

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  • Endothelial to mesenchymal transformation is induced by altered extracellular matrix in aortic valve endothelial cells

    Endothelial to mesenchymal transformation is induced by altered extracellular matrix in aortic valve endothelial cells

    PAVEC pERK staining after 48 h in culture with and without ERK inhibitor (U0126). pERK (green) and α-SMA (red) immunocytochemistry staining of PAVEC grown on 1.5 mg/ml collagen (A,D), 1.5 mg/mL collagen + 10 ng/mL TGF-β1 (B,E), 2.2 mg/mL collagen (C,F), 1.5 mg/mL collagen +20 mg/ml CS (G,J), 1.5 mg/ml collagen +20 mg/mL HA (H,K) and 1.5 mg/ml collagen +20 mg/mL DS (I,L). Samples without inhibitor are shown in A,B,C,G,H,I and samples with inhibitor are shown in D,E,F,J,K,L. Scale bar = 5 µm.

  • VEGF release from a polymeric nanofiber scaffold for improved angiogenesis

    VEGF release from a polymeric nanofiber scaffold for improved angiogenesis

    Laser confocal microscopy of electrospun nanofibers (A, B). Images were processed with Imaris software. Cells seen dispersed throughout and adhered to the scaffold. 3D modeling of the images demonstrate intimate contacts between the cells (labeled with green and blue) and the nanofiber scaffold (stained red).

  • Conjunctiva derived mesenchymal stem cell (CJMSCs) as a potential platform for differentiation into corneal epithelial cells on bioengineered electrospun scaffolds

    Conjunctiva derived mesenchymal stem cell (CJMSCs) as a potential platform for differentiation into corneal epithelial cells on bioengineered electrospun scaffolds

    Expression of Corneal epithelial-specific protein, CK3, represented by immunofluorescent staining. Nucleus stained with DAPI. Magnification ×20.

  • Application of omentum as an in vivo bioreactor for regeneration of decellularized human internal mammary artery

    Application of omentum as an in vivo bioreactor for regeneration of decellularized human internal mammary artery

    Histopathology of 2-months after transplant showed collagen formation in the media and adventitia layer with scattered area of angiogenesis and neovessels formation surrounding the vessel.

  • The effect of riboflavin/UVA cross-linking on anti-degeneration and promoting angiogenic capability of decellularized liver matrix

    The effect of riboflavin/UVA cross‐linking on anti‐degeneration and promoting angiogenic capability of decellularized liver matrix

    Characterization of DLM. (a–d) Typical images of rat liver in the decellularized process; (e) HE staining of decellularized liver matrix (DLM); (f) SEM image showing the retaining ECM and microvascular structure of DLM; (g,h) Immunofluorescence of fibronectin and collagen type I in DLM; (i) DNA content of DLM is was significantly lower than fresh liver (p < 0.05); (j,k) DAPI staining of fresh and DLM. Scar bars: a–d 1 cm, e,g,h,j,k 50 μm, f 200 μm.

  • Effect of recombinant human bone morphogenic protein 9 (rhBMP9) loaded onto bone grafts versus barrier membranes on new bone formation in a rabbit calvarial defect model

    Effect of recombinant human bone morphogenic protein 9 (rhBMP9) loaded onto bone grafts versus barrier membranes on new bone formation in a rabbit calvarial defect model

    The toluidine blue and fuchsin staining in the middle area of the bone defects in (A) DBM group and (B) DBM + rhBMP9 group. (C–F) Magnified views of the squares in (A) and (B). NB indicates new bone, and DBM shows residual materials. Black arrowheads indicate multinucleated giant cells (MNGCs) on DBM and yellow arrowheads indicate osteoblasts on newly formed bone.

  • Endothelial to mesenchymal transformation is induced by altered extracellular matrix in aortic valve endothelial cells
  • VEGF release from a polymeric nanofiber scaffold for improved angiogenesis
  • Conjunctiva derived mesenchymal stem cell (CJMSCs) as a potential platform for differentiation into corneal epithelial cells on bioengineered electrospun scaffolds
  • Application of omentum as an in vivo bioreactor for regeneration of decellularized human internal mammary artery
  • The effect of riboflavin/UVA cross‐linking on anti‐degeneration and promoting angiogenic capability of decellularized liver matrix
  • Effect of recombinant human bone morphogenic protein 9 (rhBMP9) loaded onto bone grafts versus barrier membranes on new bone formation in a rabbit calvarial defect model

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