Contrast Media & Molecular Imaging

Cover image for Vol. 11 Issue 6

Online ISSN: 1555-4317

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Wiley and Hindawi partnership

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Contrast Media & Molecular Imaging is part of an exciting new pilot partnership between Wiley and Hindawi. From 1st January 2017, the journal will become fully open access. Contrast Media & Molecular Imaging will remain a Wiley title but will be published and hosted by Hindawi, and will benefit from Hindawi’s experience and expertise in publishing open access titles. Contrast Media & Molecular Imaging will continue to undergo a rigorous peer review process ensuring that quality remains high. Manuscripts submitted on or after 16 June 2016 and accepted for publication will be published as open access articles, immediately free to read, download and share. Authors or their funder will be required to pay an Article Publication Charge upon acceptance. For further information, please click here

Recently Published Articles

  1. Dual nano-sized contrast agents in PET/MRI: a systematic review (pages 428–447)

    Afsaneh Lahooti, Saeed Sarkar, Sophie Laurent and Saeed Shanehsazzadeh

    Version of Record online: 19 JAN 2017 | DOI: 10.1002/cmmi.1719

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    This paper compares systematically recent dual contrast agents for diagnostic imaging in order to early detection in PET/ MRI and in some cases SPECT/ MRI in terms of some their characteristics such as tumor uptake, and RES uptake (especially liver) and their relaxivity rates. The best targeting results according to the selected studies are generally with peptide or engineered mAb (with lower molecular weights) with an approximate hydrodynamic size of 40 nm, PEGylated radio labeled with 64Cu or 68Ga.

  2. Magnetically driven nanoparticles: 18FDG-radiolabelling and positron emission tomography biodistribution study (pages 561–571)

    Mariarosaria De Simone, Daniele Panetta, Emilia Bramanti, Cristiana Giordano, Maria C. Salvatici, Lisa Gherardini, Arianna Menciassi, Silvia Burchielli, Caterina Cinti and Piero A. Salvadori

    Version of Record online: 4 JAN 2017 | DOI: 10.1002/cmmi.1718

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    PET imaging demonstrates that, after systematic administration, magnetic nanoparticles can be locally concentarted to a specific anatomycal site with intact vascularity by an external static magnetic field.

  3. Lentiviral transduction and subsequent loading with nanoparticles do not affect cell viability and proliferation in hair-follicle-bulge-derived stem cells in vitro (pages 550–560)

    Timo Schomann, Laura Mezzanotte, Ierry-Ann-Lym M. Lourens, John C. M. J. de Groot, Johan H. M. Frijns and Margriet A. Huisman

    Version of Record online: 15 DEC 2016 | DOI: 10.1002/cmmi.1717

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    Transduction of hair-follicle-bulge-derived stem cells with a Luc2-copGFP construct followed by subsequent loading with red-fluorescent iron-containing TMSR50 nanoparticles results in equimolar expression of both reporter molecules, it does not interfere with cellular senescence, cell viability, proliferation and differentiation and enables in vitro detection by means of fluorescence imaging (IVIS) and MRI. These results imply that MRI and molecular optical imaging can be combined to enable in vivo localization and long-term monitoring of viable hair-follicle-bulge-derived stem cells after engraftment.

  4. USPIO enhanced lymph node MRI using 3D multi-echo GRE in a rabbit model (pages 544–549)

    Sung Hun Kim, Soon Nam Oh, Hyun Seok Choi, Hyun Sil Lee, Jaeseop Jun, Yoonho Nam, Sung Hak Lee, Jin-Kwon Lee and Hae Giu Lee

    Version of Record online: 15 DEC 2016 | DOI: 10.1002/cmmi.1716

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    From 3D multi-echo GRE data, multi-echo combined T2*-weighted images, an R2* map, and a quantitative susceptibility map (QSM) were generated. Eighteen lymph nodes (nine reactive and nine metastatic) were evaluated and showed remarkable signal changes in the area of USPIO accumulation. The R2* difference before and after USPIO injection showed a significant difference for the differentiation between reactive and metastatic lymph nodes.

  5. In vivo quantification of magnetically labelled cells by MRI relaxometry (pages 535–543)

    Ulysse Gimenez, Hélène Lajous, Michèle El Atifi, Marie Bidart, Vincent Auboiroux, Pascal Henry Fries, François Berger and Hana Lahrech

    Version of Record online: 21 OCT 2016 | DOI: 10.1002/cmmi.1715

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    A cellular MRI method that quantifies a large range of magnetically labelled cells is proposed. The method is based on the simultaneous measurements of R2*, R2 and R1. Cellular relaxivities are defined in vitro and used to convert relaxation rates to cell concentration in vivo. The method was applied in a glioma model using U937 cells magnetically labelled with USPIO-NPs.