Plasma Processes and Polymers

Cover image for Vol. 11 Issue 9

Online ISSN: 1612-8869

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Recently Published Articles

  1. Inactivation of the Endotoxic Biomolecule Lipid A by Oxygen Plasma Species: A Reactive Molecular Dynamics Study

    Maksudbek Yusupov, Erik C. Neyts, Christof C. Verlackt, Umedjon Khalilov, Adri C. T. van Duin and Annemie Bogaerts

    Article first published online: 17 SEP 2014 | DOI: 10.1002/ppap.201400064

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    The interaction of reactive oxygen species (ROS) with lipid A was investigated by means of reactive MD simulations. Lipid A is the endotoxic biomolecule found in the outer membrane of gram-negative bacteria (e.g., Escherichia coli). Any deviation from its structure decreases its toxicity. This work demonstrates how ROS destroy the lipid A structure and thereby decrease its endotoxic activity.

  2. Enhancement of Angiogenesis and Epithelialization Processes in Mice with Burn Wounds through ROS/RNS Signals Generated by Non-Thermal N2/Ar Micro-Plasma

    Minh-Hien Ngo Thi, Pei-Lin Shao, Jiunn-Der Liao, Chou-Ching K. Lin and Hon-Kan Yip

    Article first published online: 17 SEP 2014 | DOI: 10.1002/ppap.201400072

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    The generated ROS/RNS signals (i) stimulate the healing process of burn wound in mice, presumably correlated with the angiogenesis (ii) and epithelialization (iii) processes, by releasing fibroblast growth factors. Microplasma device with a low operating temperature and an adjustable plasma composition provides a promising therapeutic alternative.

  3. Fabrication of a Biomimetic Hierarchical Surface Replicated from a Lotus Leaf and In Vitro Cellular Activities

    Jae Yoon Lee, Hyeongjin Lee, Yong Bok Kim and Geun Hyung Kim

    Article first published online: 17 SEP 2014 | DOI: 10.1002/ppap.201400076

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    The aim of this study is to develop a hierarchical structure on poly(ϵ-caprolactone) (PCL) surfaces to mimic the distinctive, natural hierarchical structure of a lotus leaf using two combined processes of micro-/nanocasting and plasma-etching.

  4. Efficacy of Low Temperature Plasma against SCaBER Cancer Cells

    Soheila Mohades, Nazir Barekzi and Mounir Laroussi

    Article first published online: 17 SEP 2014 | DOI: 10.1002/ppap.201400108

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    Recent work has shown that LTP can effectively kill various cancer cells in vitro and that apoptosis could be the cellular death pathway. Here, the efficacy of the plasma pencil on a squamous cell carcinoma, the SCaBER (ATCC® HTB3™) cell line, is reported. It is found that LTP or plasma activated media can kill the cancer cells in an exposure time dependent manner and that under select conditions apoptosis is elicited.

  5. Interactions of a Non-Thermal Atmospheric Pressure Plasma Effluent with PC-3 Prostate Cancer Cells

    Andrew R. Gibson, Helen O. McCarthy, Ahalm A. Ali, Deborah O'Connell and William G. Graham

    Article first published online: 12 SEP 2014 | DOI: 10.1002/ppap.201400111

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    The influence of a charge free atmospheric pressure plasma effluent on PC-3 prostate cancer cells is investigated. Under these conditions apoptosis was found to proceed via the intrinsic apoptosis pathway. Furthermore the liquid chemistry in growth media exposed to the plasma effluent is found to change over relatively long time periods. This has potential to be exploited for therapeutic purposes.