Molecular Nutrition & Food Research

Cover image for Vol. 60 Issue 7

Edited By: Hans-Ulrich Humpf

Impact Factor: 4.551

ISI Journal Citation Reports © Ranking: 2015: 5/124 (Food Science & Technology)

Online ISSN: 1613-4133

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Recently Published Articles

  1. Dietary Supplementation with Rice Bran or Navy Bean Alters Gut Bacterial Metabolism in Colorectal Cancer Survivors

    Amy M. Sheflin, Erica C. Borresen, Jay S. Kirkwood, Claudia M. Boot, Alyssa K. Whitney, Shen Lu, Regina J. Brown, Corey D. Broeckling, Elizabeth P. Ryan and Tiffany L. Weir

    Accepted manuscript online: 27 JUL 2016 04:25AM EST | DOI: 10.1002/mnfr.201500905

  2. Acute effects of dietary fatty acids on osteclastogenesis via RANKL/RANK/OPG system

    M. Carmen Naranjo, Indara Garcia, Beatriz Bermudez, Sergio Lopez, Magdalena P. Cardelo, Rocio Abia, Francisco J. G. Muriana and Sergio Montserrat-de la Paz

    Version of Record online: 27 JUL 2016 | DOI: 10.1002/mnfr.201600303

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    Postprandial triglyceride-rich lipoproteins are metabolic entities with osteoclastogenic activity and this property is related to the type of dietary fatty acid in meals. The osteoclastogenic potency is presented to be as follows: saturated fatty acids > MUFAs = PUFAs. These exciting findings open opportunities for developing nutritional strategies with olive oil as the principal dietary source of MUFAs, notably oleic acid, to prevent development and progression of osteoclast-related diseases.

  3. Does epicatechin contribute to the acute vascular function effects of dark chocolate? A randomized, crossover study

    James I. Dower, Johanna M. Geleijnse, Paul A. Kroon, Mark Philo, Marco Mensink, Daan Kromhout and Peter C. H. Hollman

    Version of Record online: 26 JUL 2016 | DOI: 10.1002/mnfr.201600045

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    Acute vascular effects of pure epicatechinimage and dark chocolateimage are compared. The bioavailability of epicatechin does not differ between pure epicatechin and dark chocolate. Improvements in vascular function after pure epicatechin and chocolate are also not significantly different and the bioavailability is similar. These results suggest a role for epicatechin.

  4. Hydroxytyrosol mildly improve cognitive function independent of APP processing in APP/PS1 mice

    Yunhua Peng, Chen Hou, Ziqi Yang, Caixia Li, Liyan Jia, Jing Liu, Ying Tang, Le Shi, Yongqin Li, Jiangang Long and Jiankang Liu

    Version of Record online: 25 JUL 2016 | DOI: 10.1002/mnfr.201600332

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    Hydroxytyrosol (HT) can be transported across the blood–brain-barrier and exert roles in neurons. HT improves electroencephalography activity and marginally benefits cognitive behavior of Alzheimer's disease (AD) mice. These results suggest that HT may represent as a functional ingredient in the Mediterranean diet in ameliorating AD-involved neuronal impairment via modulating mitochondrial oxidative stress, inflammation, and apoptosis without affecting AβPP processing.

  5. Perinatal maternal high-fat diet promotes alterations in hepatic lipid metabolism and resistance to the hypolipidemic effect of fish oil in adolescent rat offspring

    Lorraine S. Oliveira, Luana L. Souza, Aline F. P. Souza, Aline Cordeiro, George E. G. Kluck, Georgia C. Atella, Isis H. Trevenzoli and Carmen C. Pazos-Moura

    Version of Record online: 25 JUL 2016 | DOI: 10.1002/mnfr.201600171

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    In adolescent offspring from maternal standard diet, fish oil (FO) increases serum docosahexanoic acid and eicosapentanoic acid and modulates key mechanisms of hepatic lipid metabolism, reducing serum and hepatic cholesterol and triglyceride content. In adolescent offspring from maternal high-fat diet (HFD), the low serum n-3 PUFA concentration and hepatic molecular changes, as ABCG8, SREBP-1, and acetyl CoA carboxylase (ACC) expression, may disturb the FO effect, contributing to the resistance to a hypolipidemic FO effect.