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Recently Published Articles

  1. Highly Transparent Conducting Nanopaper for Solid State Foldable Electrochromic Devices

    Wenbin Kang, Meng-Fang Lin, Jingwei Chen and Pooi See Lee

    Version of Record online: 30 SEP 2016 | DOI: 10.1002/smll.201600979

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    By leveraging the unique surface properties of nanocellulose, foldable nanopaper electrode with outstanding electro-optical performance is achieved. A fully foldable transparent solid state electrochromic device based on this mechanically compliant transparent conductor with excellent stability against folding is realized. The foldable transparent electrode as well as the foldable device may find broad applications for futuristic wearable and portable electronics.

  2. Probing Membrane Viscosity and Interleaflet Friction of Supported Lipid Bilayers by Tracking Electrostatically Adsorbed, Nano-Sized Vesicles

    Seyed R. Tabaei, Jurriaan J. J. Gillissen and Nam-Joon Cho

    Version of Record online: 30 SEP 2016 | DOI: 10.1002/smll.201601561

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    The viscosity and the interleaflet friction coefficient of lipid bilayers are measured by tracking the diffusional motion of individual nano-sized lipid vesicles that are electrostatically targeted onto a supported lipid bilayer (SLB). The vesicle motion is coupled to that of a nanoscopic lipid cluster in the upper leaflet and induces slippage between the upper and the lower leaflets of the SLB.

  3. Facile Fabrication of Tumor Redox-Sensitive Nanoassemblies of Small-Molecule Oleate Prodrug as Potent Chemotherapeutic Nanomedicine

    Cong Luo, Jin Sun, Bingjun Sun, Dan Liu, Lei Miao, Tyler Jay Goodwin, Leaf Huang and Zhonggui He

    Version of Record online: 30 SEP 2016 | DOI: 10.1002/smll.201601597

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    To bridge the gap between hydrophobic lipid prodrugs of paclitaxel and favorable antitumor efficacy, a smart redox-sensitive prodrug-nanosystem has been designed. The uniquely engineered stimulus-responsive prodrug nanoassemblies, with high drug loading (over 50%, w/w), on-demand drug release within tumor cells, and potent antitumor efficacy, hold great potential to be used as a promising chemotherapeutic nanomedicine in cancer therapy.

  4. Local Mechanical Perturbation Provides an Effective Means to Regulate the Growth and Assembly of Functional Peptide Fibrils

    Arpad Karsai, Teri Jo Slack, Hamed Malekan, Fadi Khoury, Wei-Feng Lin, Victoria Tran, Daniel Cox, Michael Toney, Xi Chen and Gang-yu Liu

    Version of Record online: 30 SEP 2016 | DOI: 10.1002/smll.201601657

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    New nuclei of MUC1-Q11 amyloid are created by cutting fibrils along x-axis in 23 nm periodicity. Growth and reassembly of fibrils occur at both ends of newly formed nuclei.

  5. Bacterial Hyaluronidase Self-Triggered Prodrug Release for Chemo-Photothermal Synergistic Treatment of Bacterial Infection

    Haiwei Ji, Kai Dong, Zhengqin Yan, Chao Ding, Zhaowei Chen, Jinsong Ren and Xiaogang Qu

    Version of Record online: 30 SEP 2016 | DOI: 10.1002/smll.201601729

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    A novel platform for targeted on-demand prodrug ascorbic acid (AA) delivery is fabricated using a bacterial hyaluronidase sensitive graphene-mesoporous silica nanosheet@hyaluronic acid-magnetic nanoparticles as the nanocarrier to treat bacterial infections. The released AA can be converted to detrimental •OH in situ on the surface of bacteria. With the chemo-photothermal synergistic effect, the designed antibacterial system can effectively inactivate bacteria and disperse stubborn biofilm.