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Recently Published Articles

  1. Macrophages as Active Nanocarriers for Targeted Early and Adjuvant Cancer Chemotherapy

    Jingxing Si, Shiqun Shao, Youqing Shen and Kai Wang

    Version of Record online: 25 AUG 2016 | DOI: 10.1002/smll.201601282

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    The critical considerations and recent advancements in using macrophages as carriers for nanomedicines are reviewed. Key factors determining the efficacy of macrophage-based nanomedicines are highlighted. The goal of this review is to contribute to the rational design of EPR-independent tumor-targeting active nanomedicines for targeted early and adjuvant cancer chemotherapy.

  2. Constructing Well-Ordered CdTe/TiO2 Core/Shell Nanowire Arrays for Solar Energy Conversion

    Ahmed Al-Haddad, Zijie Wang, Min Zhou, Samar Tarish, Ranjith Vellacheri and Yong Lei

    Version of Record online: 25 AUG 2016 | DOI: 10.1002/smll.201601412

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    Well-ordered CdTe/TiO2 heteronanostructure arrays are fabricated via a convenient anodic aluminum oxide template-directed approach and applied to photoelectrochemistry and solar energy devices. Both the CdTe and TiO2 present a decent crystalline quality. In comparison to the photoanode with only TiO2 nanotube array, the CdTe/TiO2 heteronanostructure electrodes possess a dramatic performance improvement.

  3. Microenvironment-Responsive Three-Pronged Approach Breaking Traditional Chemotherapy to Target Cancer Stem Cells for Synergistic Inoperable Large Tumor Therapy

    Yan Li, Ruilong Zhang, Zhiguo Lu, Guanghui Ma, Lei Chen, Qunwei Tang and Xin Zhang

    Version of Record online: 24 AUG 2016 | DOI: 10.1002/smll.201601932

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    Three-pronged nanoparticles (NPs) that can efficiently prohibit the proliferation of large tumor are developed for inoperable large tumor therapy. The NPs achieve spatially and temporally controlled release of drugs in target sites. The NPs induce the apoptosis of differentiated cancer cells, cancer stem cells, and vascular niches simultaneously. Importantly, the three-pronged NPs inhibit the growth of large tumor without recurrence.

  4. Scalable Fabrication of Multiplexed Plasmonic Nanoparticle Structures Based on AFM Lithography

    Jianmei Chen, Yinghui Sun, Liubiao Zhong, Weijing Shao, Jing Huang, Feng Liang, Zequn Cui, Zhiqiang Liang, Lin Jiang and Lifeng Chi

    Version of Record online: 24 AUG 2016 | DOI: 10.1002/smll.201602250

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    A controllable and scalable strategy is developed to fabricate multiplexed plasmonic nanoparticle structures by mechanical scratching with AFM lithography, which exhibit multiplex plasmonic properties and surface-enhanced Raman scattering responses. It offers an intuitive way to explore the plasmonic effects on performance of organic light-emitting diodes device integrating with multiplexed plasmonic nanostructures.

  5. Highly Efficient Water Oxidation Photoanode Made of Surface Modified LaTiO2N Particles

    Seiji Akiyama, Mamiko Nakabayashi, Naoya Shibata, Tsutomu Minegishi, Yusuke Asakura, Md. Abdulla-Al-Mamun, Takashi Hisatomi, Hiroshi Nishiyama, Masao Katayama, Taro Yamada and Kazunari Domen

    Version of Record online: 24 AUG 2016 | DOI: 10.1002/smll.201601929

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    An improved variation of highly active/durable O2- evolving LaTiO2N powder-based photoelectrode has been fabricated by pre-cleaning the powder with mild polysulfonic acid and by homogeneous deposition of CoOx co-catalyst aided by microwave annealing. Fabricated into particle-transferred electrodes on Ti, the modified LaTiO2N serves as a highly active photoanode, achieving 8.9 mA cm−2 of the photocurrent density at 1.23 V versus RHE and longer active periods than those by previous methods.