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Recently Published Articles

  1. Interparticle Forces Underlying Nanoparticle Self-Assemblies

    Dan Luo, Cong Yan and Tie Wang

    Article first published online: 5 OCT 2015 | DOI: 10.1002/smll.201501783

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    Nanoparticle self-assemblies are considered highly promising nanomaterials for future industrialization. Here, recent progress in the synthesis of nanoparticle self-assemblies with respect to interparticle forces, which determine their collective properties, is highlighted. A comprehensive perspective for the future design and fabrication of nanoparticle assemblies with excellent properties and applications is presented.

  2. Helium Ion Microscopy Visualizes Lipid Nanodomains in Mammalian Cells

    Matthias Schürmann, Natalie Frese, André Beyer, Peter Heimann, Darius Widera, Viola Mönkemöller, Thomas Huser, Barbara Kaltschmidt, Christian Kaltschmidt and Armin Gölzhäuser

    Article first published online: 5 OCT 2015 | DOI: 10.1002/smll.201501540

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    Helium ion microscopy is capable of imaging biological specimens without any conductive coating, and it allows the identification of nanodomains in the ultrastructure of membranes with 1.5 nm resolution. The shape of these nanodomains is preserved by fixation of the surrounding unsaturated fatty acids, while saturated fatty acids inside the nanodomains are selectively removed.

  3. Novel Mn3[Co(CN)6]2@SiO2@Ag Core–Shell Nanocube: Enhanced Two-Photon Fluorescence and Magnetic Resonance Dual-Modal Imaging-Guided Photothermal and Chemo-therapy

    Dongdong Wang, Zhen Guo, Jiajia Zhou, Jian Chen, Gaozheng Zhao, Ruhui Chen, Mengni He, Zhenbang Liu, Haibao Wang and Qianwang Chen

    Article first published online: 5 OCT 2015 | DOI: 10.1002/smll.201502102

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    A versatile Mn3[Co(CN)6]2@SiO2@Ag coreshell nanocube is prepared by a simple coprecipitation method which possesses T1–T2 dual-modal MRI ability and bright two-photon fluorescence (TPF) imaging when excited at 730 nm. The TPF imaging intensity displays 1.85-fold enhancement after loading of Ag nanoparticles.

  4. Controlling the Nanoscale Rotational Behaviors of Nanoparticles on the Cell Membranes: A Computational Model

    Qiu-Ju Ji, Bing Yuan, Xue-Mei Lu, Kai Yang and Yu-Qiang Ma

    Article first published online: 5 OCT 2015 | DOI: 10.1002/smll.201501885

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    Nanoparticles prefer to bind to a membrane with a surface coated by short or rigid ligands, as shown by computer simulations. To realize such a preferred configuration, the nanoparticle can spontaneously spin itself on the membrane surface, no matter what its initial orientation is.

  5. Photonic Crystal Hydrogel Enhanced Plasmonic Staining for Multiplexed Protein Analysis

    Zhongde Mu, Xiangwei Zhao, Yin Huang, Meng Lu and Zhongze Gu

    Article first published online: 5 OCT 2015 | DOI: 10.1002/smll.201501829

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    By the hybridization of plasmonic nanoparticles and a photonic crystal structure through plasmonic staining of the protein-modified hydrogel, improved SERS analysis of multiplexed protein is realized. In comparison, the SERS signals from the plasmonic stained inverse opal photonic crystal hydrogel is about five times of those from plamonic stained nonporous hydrogel.