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Recently Published Articles

  1. Towards the Development of Smart 3D “Gated Scaffolds” for On-Command Delivery

    Núria Mas, Daniel Arcos, Lorena Polo, Elena Aznar, Sandra Sánchez-Salcedo, Félix Sancenón, Ana García, M. Dolores Marcos, Alejandro Baeza, María Vallet-Regí and Ramón Martínez-Máñez

    Article first published online: 30 JUL 2014 | DOI: 10.1002/smll.201401227

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    A new approach towards the design of “gated scaffolds” based on the combination of capped mesoporous silica nanoparticles (MSNs) with porous biomaterials is reported. Using this approach, a 3D gelatin-based scaffold able to selectively deliver cargo in the presence of an APase enzyme is prepared and tested. This new design opens up the possibility of developing new smart biomaterials with advanced drug-delivery features.

  2. Controlling Lipid Membrane Architecture for Tunable Nanoplasmonic Biosensing

    Goh Haw Zan, Joshua A. Jackman, Seong-Oh Kim and Nam-Joon Cho

    Article first published online: 30 JUL 2014 | DOI: 10.1002/smll.201400518

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    Tunable nanoplasmonic biosensing for lipid and protein applications is reported based on controlling lipid membrane architecture on surfaces. The interaction of a peptide with lipid membranes is highly sensitive to the membrane architecture on top of plasmonic nanodisks, and the measurement response varies in a manner which is consistent with the surrounding lipid environment.

  3. Dendrite-Free Nanostructured Anode: Entrapment of Lithium in a 3D Fibrous Matrix for Ultra-Stable Lithium–Sulfur Batteries

    Xin-Bing Cheng, Hong-Jie Peng, Jia-Qi Huang, Fei Wei and Qiang Zhang

    Article first published online: 29 JUL 2014 | DOI: 10.1002/smll.201401837

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    Entrapment of free lithium in a 3D fibrous Li7B6 framework allows LiB nanostructured anodes with stable interfaces between the electrolyte and the electrode, which retards the formation of lithium dendrites. A lithium–sulfur cell with a nanostructured anode is created with a high Coulombic efficiency and high capacity retention rate of 36.3% after 2000 cycles.

  4. A Radial Flow Microfluidic Device for Ultra-High-Throughput Affinity-Based Isolation of Circulating Tumor Cells

    Vasudha Murlidhar, Mina Zeinali, Svetlana Grabauskiene, Mostafa Ghannad-Rezaie, Max S. Wicha, Diane M. Simeone, Nithya Ramnath, Rishindra M. Reddy and Sunitha Nagrath

    Article first published online: 29 JUL 2014 | DOI: 10.1002/smll.201400719

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    The isolation of circulating tumor cells (CTCs) is addressed by emerging microfluidic technologies employing different isolation techniques. Here, a radial flow microfluidic device, the OncoBean Chip, is presented. The device performs affinity-based capture of CTCs with high-throughput.

  5. Strong Thermo-Induced Single And Two-Photon Green Luminescence In Self-Organized Peptide Microtubes

    S. Semin, A. van Etteger, L. Cattaneo, N. Amdursky, L. Kulyuk, S. Lavrov, A. Sigov, E. Mishina, G. Rosenman and Th. Rasing

    Article first published online: 29 JUL 2014 | DOI: 10.1002/smll.201401602

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    Diphenylalanine peptide nano- and microtubes formed by self-assembly demonstrate strongly enhanced and tunable single-photon and two-photon luminescence in the visible range, which appears after heat- or laser treatment of these self-organized peptide microtubes. This process significantly extends the functionality of these microstructures and can trigger a new interest in the optical properties of structures based on short peptides.