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Recently Published Articles

  1. Nanoparticle-Based Manipulation of Antigen-Presenting Cells for Cancer Immunotherapy

    Ronnie H. Fang, Ashley V. Kroll and Liangfang Zhang

    Article first published online: 2 SEP 2015 | DOI: 10.1002/smll.201501284

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    Immunotherapeutic approaches to cancer treatment have been gaining significant traction in the clinic. Of the different modalities, the goal of anticancer vaccination is to train the body to detect and eliminate tumors. Here the application of nanoparticle technology towards the development of more effective vaccine formulations that address the limitations of current approaches is discussed.

  2. Masthead: (Small 33/2015)

    Article first published online: 2 SEP 2015 | DOI: 10.1002/smll.201570203

  3. Laser Transfer: Laser Transfer of Metals and Metal Alloys for Digital Microfabrication of 3D Objects (Small 33/2015) (page 4030)

    Michael Zenou, Amir Sa'ar and Zvi Kotler

    Article first published online: 2 SEP 2015 | DOI: 10.1002/smll.201570199

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    3D laser printing in ambient conditions is demonstrated by M. Zenou and co-workers on page 4082. The fabrication of the 3D structure consists of overlapped copper droplets a few tens of femtoliters each. The fast solidification of the molten metal droplet as it lands reduces its spreading, allowing the fabrication of high aspect-ratio structures. The letters shown in the image are 50 μm wide and are gradually of a higher height from 40 μm (‘s’) to 190 μm (‘l’). The image was taken with tilt of 55 degrees.

  4. Drug Delivery: Gold Nanocluster Embedded Albumin Nanoparticles for Two-Photon Imaging of Cancer Cells Accompanying Drug Delivery (Small 33/2015) (page 4074)

    Rumi Khandelia, Satyapriya Bhandari, Uday Narayan Pan, Siddhartha Sankar Ghosh and Arun Chattopadhyay

    Article first published online: 2 SEP 2015 | DOI: 10.1002/smll.201570201

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    The fabrication of biocompatible gold nanocluster-embedded albumin nanoparticles for potential theranostic applications is reported by A. Chattopadhyay and co-workers on page 4075. Anti-cancer drug doxorubicin-loaded nanoparticles are internalized by cervical cancer HeLa cells in vitro, leading to apoptotic cell death. Simultaneously, imaging can be achieved by using one- and two-photon excitation, with the two-photon excitation/emission wavelengths lying in the biological window of 650–900 nm. The luminescent nanoparticles may serve as model platforms for theranostics.

  5. Edge-Cutting Transfer: Deterministic Assembly of Flexible Si/Ge Nanoribbons via Edge-Cutting Transfer and Printing for van der Waals Heterojunctions (Small 33/2015) (page 4029)

    Qinglei Guo, Miao Zhang, Zhongying Xue, Gang Wang, Da Chen, Ronggen Cao, Gaoshan Huang, Yongfeng Mei, Zengfeng Di and Xi Wang

    Article first published online: 2 SEP 2015 | DOI: 10.1002/smll.201570198

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    A combined and controlled approach called edge-cutting transfer (E-CT) is used on page 4140 by Y. Mei, Z. Di, and co-workers to precisely generate spatially aligned Si/Ge nanoribbons with a designed geometry. The suspended nanoribbons are formed by the selective etching of a buried oxide layer, then a slab of cured PDMS is contacted with the patterned donor source. Pulling away the PDMS cuts the suspended Si/Ge nanoribbons off the substrate in a controllable manner, obtaining Si/Ge nanoribbon arrays on a flexible PDMS substrate.

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