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Recently Published Articles

  1. Micro- and Nanotechnologies for Intracellular Delivery

    Li Yan, Jinfeng Zhang, Chun-Sing Lee and Xianfeng Chen

    Article first published online: 28 AUG 2014 | DOI: 10.1002/smll.201401532

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    Cell membranes, a biological barrier, strictly limit intracellular delivery of drugs and biomolecules, resulting in poor therapeutic efficiency. In this review, the focus is on summarizing the nanomaterial routes involved in making use of a collection of receptors for the targeted delivery of drugs and biomolecules and the physical ways of applying micro- and nanotechnologies for high-throughput intracellular delivery.

  2. Single Nanowire Resistive Nano-heater for Highly Localized Thermo-Chemical Reactions: Localized Hierarchical Heterojunction Nanowire Growth

    Junyeob Yeo, Gunho Kim, Sukjoon Hong, Jinhwan Lee, Jinhyeong Kwon, Habeom Lee, Heeseung Park, Wanit Manoroktul, Ming-Tsang Lee, Bong Jae Lee, Costas P. Grigoropoulos and Seung Hwan Ko

    Article first published online: 28 AUG 2014 | DOI: 10.1002/smll.201401427

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    A single nanowire resistive nano-heater (RNH) is fabricated, and it is demonstrated that the RNH can induce highly localized temperature fields, which can trigger highly localized thermo-chemical reactions to grow hierarchical nanowires directly at the desired specific spot such as ZnO nanowire branch growth on a single Ag nanowire.

  3. TiO2-Decorated Graphite Nanoplatelet Nanocomposites for High-Temperature Sensor Applications

    Ashish Kumar Mishra and Liping Huang

    Article first published online: 28 AUG 2014 | DOI: 10.1002/smll.201401418

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    This study demonstrates a higher thermal stability of anatase TiO2 NPs in TiO2-GNPs nanocomposites compared to bare TiO­2 NPs for high temperature applications. Thermal shock responsive grain growth and Raman signature of TiO­2 in these nanocomposites enable them to map the temperature of harsh environments with a high accuracy of nearly 98%.

  4. Donut-Shaped Li4Ti5O12 Structures as a High Performance Anode Material for Lithium Ion Batteries

    Anulekha K. Haridas, Chandra S. Sharma and Tata N. Rao

    Article first published online: 28 AUG 2014 | DOI: 10.1002/smll.201303894

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    Lithium titanate (LTO) spinel 3D porous sub-micrometer donuts synthesized by combined sol-gel and electrospraying reveal a wall thickness of 200–250 nm with grain sizes in the range of 60–100 nm. Electrochemical testing of sub-micrometer donuts in half-cell mode exhibited a reversible specific capacity of 141 mAh/g even after 200 cycles of charging and discharging at 1C rate. The LTO structures with nanograins effectively reduce the Li ion diffusion path length, providing easy charge and discharge with good cyclability.

  5. In Vivo Studies of Nanostructure-Based Photosensitizers for Photodynamic Cancer Therapy

    Siew Hui Voon, Lik Voon Kiew, Hong Boon Lee, Siang Hui Lim, Mohamed Ibrahim Noordin, Anyanee Kamkaew, Kevin Burgess and Lip Yong Chung

    Article first published online: 28 AUG 2014 | DOI: 10.1002/smll.201401416

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    Photosensitizers for photodynamic cancer therapy usually suffer from low solubility and lack of tumor specificity. To improve their physicochemical and tumor targeting properties, they are incorporated into nanostructures. This review summarizes the in vivo efficacy of different types of nanostructure-based photosensitizers that have advanced to animal evaluation stage. It also highlights some related issues and challenges in their development.