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Recently Published Articles

  1. Translocation Pathway-Dependent Assembly of Streptavidin- and Antibody-Binding Filamentous Virus-Like Particles

    Eun Joong Kim, Chang Su Jeon, Inseong Hwang and Taek Dong Chung

    Version of Record online: 20 OCT 2016 | DOI: 10.1002/smll.201601693

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    Antibody- and streptavidin-binding filamentous virus-like particles (VLPs) are assembled by tweaking translocation pathways and relative expression levels of the recombinant viral capsids. The vertically immobilized multifunctional VLPs on microspheres mimic cellular microvilli-like structures, which are known to enhance receptor–ligand interactions due to dramatically expanded flexible surface area.

  2. MoS2/Rubrene van der Waals Heterostructure: Toward Ambipolar Field-Effect Transistors and Inverter Circuits

    Xuexia He, WaiLeong Chow, Fucai Liu, BengKang Tay and Zheng Liu

    Version of Record online: 20 OCT 2016 | DOI: 10.1002/smll.201602558

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    The 2D material/organic crystal heterostructure is a promising artificial structure to realize unique electronic properties. By fabricating MoS2/rubrene heterostructures, novel organic–inorganic MoS2/rubrene field-effect transistors are successfully synthesized. High-performance ambipolar behavior is achieved in these devices. CMOS (complementary metal oxide semiconductor) inverter circuits also show good performance with a gain of 2.3 at a switching threshold voltage of −26 V.

  3. Targeted Co-delivery of PTX and TR3 siRNA by PTP Peptide Modified Dendrimer for the Treatment of Pancreatic Cancer

    Yang Li, Hebin Wang, Kai Wang, Qinglian Hu, Qi Yao, Youqing Shen, Guocan Yu and Guping Tang

    Version of Record online: 20 OCT 2016 | DOI: 10.1002/smll.201602697

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    A new type of tumor-targeted nanovehicle peptide-conjugated PSPG (PSPGP) is successfully synthesized for co-delivery of paclitaxel (PTX) and TR3 small interfering RNA (siRNA). In vitro and in vivo investigations demonstrate that the redox-responsive PSPGP exhibit enhanced endosomal escape and intracellular degradation, which facilitate PTX and TR3 siRNA release, effectively improving the antitumor efficacy.

  4. Graphene Oxide Nanosheets Retard Cellular Migration via Disruption of Actin Cytoskeleton

    Xin Tian, Zaixing Yang, Guangxin Duan, Anqing Wu, Zonglin Gu, Leili Zhang, Chunying Chen, Zhifang Chai, Cuicui Ge and Ruhong Zhou

    Version of Record online: 20 OCT 2016 | DOI: 10.1002/smll.201602133

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    Graphene oxide (GO) nanosheets retard cell migration along with disruption of intracellular actin filaments. GO nanosheets exhibit strong binding capacity of actin monomers, leading to significant changes to their secondary structures. Simulation results show that GO nanosheets can insert into the interstrand gap of actin tetramer and broke the tetramer.

  5. Metal-Organic Frameworks for CO2 Chemical Transformations

    Hongming He, Jason A. Perman, Guangshan Zhu and Shengqian Ma

    Version of Record online: 20 OCT 2016 | DOI: 10.1002/smll.201602711

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    CO2 triggers a series of environmental and energy problems as the primary greenhouse gas in our daily life. MOFs (metal-organic frameworks) are applied as outstanding heterogeneous catalysts for CO2 chemical transformations. A systematic overview of the development of MOF-based catalysts for CO2 chemical transformations are reviewed, from the first example to the most recent publication.