5_09/2009Stem cells: Small 9/2009

The cover image shows notch ligands presenting artificial 3D thymic microenvironments that are created on inverted colloidal crystal scaffolds utilizing a layer-by-layer molecular assembly technique. A multicomponent layer-by-layer film substitutes the function of thymic stromal cells and successfully supports ex vivo T-cell differentiation of human hematopoietic stem cells. For more information, please read the Communication “Notch Ligand Presenting Acellular 3D Microenvironments for ex vivo Human Hematopoietic Stem-Cell Culture made by Layer-By-Layer Assembly” by J. Lee and N. A. Kotov, beginning on page 1008.

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