© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor-in-Chief: José Oliveira; Deputy Editors: Yan Li, Guangchen Xu
Online ISSN: 1613-6829
Associated Title(s): Advanced Electronic Materials, Advanced Energy Materials, Advanced Engineering Materials, Advanced Functional Materials, Advanced Healthcare Materials, Advanced Materials, Advanced Materials Interfaces, Advanced Materials Technologies, Advanced Optical Materials, Advanced Science, Particle & Particle Systems Characterization
Biosensors: CdSe Quantum Dots Enhance Electrical and Electrochemical Signals of Nanogap Devices for Bioanalysis (Small 21/2012)
Electrical and electrochemical signals are enhanced by CdSe quantum dots in a nanogap device for biotin–streptavidin sensing events, as demonstrated by X.-J. Huang and co-workers on page 3274. By employing CdSe quantum dots, the ejection of the conduction-band electrons to the streptavidin, with a concomitant transfer of electrons from the chain of biotin–streptavidin to the gold nanoparticle electrode, yields an enhanced current signal. This work could provide a massive multiplexing, high-throughput, and high-sensitivity technique for biosensing through the use of large microelectrode arrays.