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Recently Published Articles
- Photothermally Controlled Gene Delivery by Reduced Graphene Oxide–Polyethylenimine Nanocomposite
Hyunwoo Kim and Won Jong Kim
Article first published online: 21 MAY 2013 | DOI: 10.1002/smll.201202636
Phototriggered gene transfection is enabled by a novel nano-sized PEG–BPEI–rGO nanocomposite, developed by conjugating polymers with reduced graphene oxide (rGO) for photothermal gene transfection. This new concept of an NIR-responsive nanocomposite could provide significant insight to design the gene carriers endowed with controlled and advanced target-specific gene delivery.
- Fluorescent DNA Hydrogels Composed of Nucleic Acid-Stabilized Silver Nanoclusters
Weiwei Guo, Ron Orbach, Iris Mironi-Harpaz, Dror Seliktar and Itamar Willner
Article first published online: 21 MAY 2013 | DOI: 10.1002/smll.201300055
Y-shaped DNA units functionalized with Ag-nanoclusters are crosslinked by nucleic acids to yield fluorescent hydrogels with controlled luminescence properties.
- Enhanced Photocatalytic Performances of CeO2/TiO2 Nanobelt Heterostructures
Jian Tian, Yuanhua Sang, Zhenhuan Zhao, Weijia Zhou, Dongzhou Wang, Xueliang Kang, Hong Liu, Jiyang Wang, Shaowei Chen, Huaqiang Cai and Hui Huang
Article first published online: 17 MAY 2013 | DOI: 10.1002/smll.201202346
The enhanced photocatalytic performance of CeO2/TiO2 heterostructured nanobelts is attributed to a novel capture–photodegradation–release degradation mechanism. During the photocatalytic process, MO molecules are captured by CeO2 nanoparticles on the surface of the heterostructure, then quickly photodegraded under UV or visible light irradiation, and ultimately the degradation products are released to external environment.
- Uptake Kinetics and Nanotoxicity of Silica Nanoparticles Are Cell Type Dependent
Julia Blechinger, Alexander T. Bauer, Adriano A. Torrano, Christian Gorzelanny, Christoph Bräuchle and Stefan W. Schneider
Article first published online: 17 MAY 2013 | DOI: 10.1002/smll.201301004
A set of experiments comparing the cytotoxicity and uptake behavior of silica nanoparticles into cells is presented. Human vascular endothelial cells (HUVEC) are more efficient in nanoparticle uptake than cervix carcinoma cells (HeLa), within the first 4 h of incubation. After 10 or 24 h, the mean number of intracellular particles for HeLa cells increases dramatically, becoming larger than the one for HUVECs. HUVECs show increased sensitivity towards silica nanoparticles when compared to HeLa cells. These results show nanotoxicity has to be assessed for each cell type individually.
- You have free access to this contentFilling Knowledge Gaps that Distinguish the Safety Profiles of Nano versus Bulk Materials (pages 1426–1427)
Yuliang Zhao, Andre Nel and Kristina Riehemann
Article first published online: 16 MAY 2013 | DOI: 10.1002/smll.201300500