© SIOC, CAS, Shanghai & WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editors: Guozhen Ji, Shengming Ma
Online ISSN: 1614-7065
Associated Title(s): Chemistry - A European Journal, Chemistry – An Asian Journal, Israel Journal of Chemistry, The Chemical Record
Hong Liang, Huayu Tian, Mingxiao Deng and Xuesi Chen
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500390
Gold nanoparticles have seen unprecedented development in biomedical field, particularly for caner theranostics. This review introduces methods for preparing various shapes of gold nanoparticles and describes their current applications in the field of cancer treatment. Moreover, the review presents the development routes and current issues of gold nanoparticles in clinical theranostics.
Yanfeng Jing, Jiaojiao Meng, Yunyun Liu and Jie-Ping Wan
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500420
In the presence of TCT organocatalyst, the direct syntheses of alkyl acrylates and chromenones have been realized via three-component reactions of aryl aldehydes, alcohols and cyano acetamide.
Yanli Dong, Xiaomei Zhao and Renhua Liu
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500357
A green and economical catalyst system, 4-OH-TEMPO/TCQ/TBN/HCl, for the aerobic oxidation of a broad range of primary and secondary alcohols to the corresponding carbonyl compounds has been developed. These reactions proceed without transition-metals under mild conditions with excellent yields.
Liang Wang, Zhan Li, Xing Qu and Wangming Peng
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500354
A highly efficient Rh(III)-catalyzed direct CH arylation of pyrrole derivatives with aryl boronic acids under mild conditions has been developed. The methodology features wide substrate scope and excellent functional group compatibility (20 examples, up to 98% yield).
Meijuan Yuan, Yewen Fang, Li Zhang, Xiaoping Jin, Minjia Tao, Qilin Ye, Ruifeng Li, Jinjian Li, Hui Zheng and Juejun Gu
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500414
Yongyun Zhou, Shanshan Liu, Hualei Chen, Jingchao Chen, Weiqing Sun, Sifeng Li, Qingjing Yang and Baomin Fan
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500392
A tandem isomerization/hydroarylation reaction of oxabenzonorbornadienes and arylacetylenes was realized by using AgOTf as catalyst. 1,1-Diarylethylenes could be easily generated as products in moderate to good yields in this tandem reaction.
Jinsheng Cheng, Weihong Wan and Wenjuan Zhu
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500339
A facile one-pot solvothermal approach to synthesize TiO2 nanobelt/graphene composites (TiO2/GR) was developed. The reduction of graphene oxide (GO) nanosheets was accompanied by generation of TiO2/GR in one-step. In vitro experiments revealed that the renal cancer (RENCA) cell viability decreased sharply to 4.72% in the presence of the resulting composites in the near infrared light (NIR) window.
Xiudong Yang, Xue Li, Ying Xu, Zifeng Pi, Na Lin, Zhiqiang Liu and Fengrui Song
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500307
The mechanism of incompatibility of P. ginseng and V. nigrum L. was studied from the aspects of substance basis and metabolic profiles using ESI-MS and UPLC-MSn.
Deyan Kong, Xinli Xiao, Xueying Qiu, Wenbo Zhang and Yulin Yang
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500343
Hydroxyapatite (HAp) nanorods with high aspect ratio have been successfully synthesized via the hydrolysis of the precursor CaHPO4 at 60°C at atmospheric pressure. The as-prepared CaHPO4 sample using CTAB as surfactant is well crystallized at the first precipitation step. At the second hydrolysis step, the CTA+ and OH− act to control the formation and growth of HAp nanorods. The HAp nanorods modified with suitable surfactants are of great potential applications in drug delivery system.
Jing Sun, Hui Gong and Chaoguo Yan
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500332
Three-component reactions of substituted pyridines, isatins with methyl propiolate, or dimethyl acetylenedicarboxylate afforded spiro[3H-indole-3,2′-[2H,9aH-pyrido[2,1-b][1,3]oxazines], which in turn reacted with N-arylmaleamide to give novel spirooxindoline fused [1,3]oxazines in good yields.
Xie Han, Xiaoyi Lü, Zhao Chen, Guangao Yu, Jun Yin and Shenghua Liu
Article first published online: 12 AUG 2015 | DOI: 10.1002/cjoc.201500324
We designed and synthesized a gold(I) complex that exhibited aggregation-induced emission in acetonitrile-water mixtures. It showed high selectivity and sensitivity for Hg2+ in acetonitrile-water (1:1, V:V) solution. Dynamic light scattering measurements were conducted to verify that the addition of Hg2+ changed the particle size and induced fluorescence quenching.
Yafang Tan, Xiaohui Sun, Fuyue Dong, Haiyan Tian and Renwang Jiang
Article first published online: 22 JUL 2015 | DOI: 10.1002/cjoc.201500276
Six new quinoxlinetanshinones 1–6 were isolated from the combinatorial modified semi-synthetic mixture. These quinoxlinetanshinones demonstrated strong DNA binding properties.
Lianhui Peng, Pengcheng Zhu, Xianggao Meng and Chun Zhang
Article first published online: 22 JUL 2015 | DOI: 10.1002/cjoc.201500293
Selective recognition of different guests for hexaphenylbenzene bromides in the solid state.
Chengqiao Cao, Wenbin Wang, Fan Zhang, Nianyu Huang and Kun Zou
Article first published online: 22 JUL 2015 | DOI: 10.1002/cjoc.201500341
A high-efficient and stereo-specific approach for synthesizing (E)-2-styryl-tetrahydrobenzo[d]thiazoles via TMSCl-catalyted direct sp3 C-H alkenylation of 2-methyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one under metal-free conditions has been developed.
Mingliang Sun, Tianbo Zhao, Jia Wang, Zhaofei Ma and Fengyan Li
Article first published online: 22 JUL 2015 | DOI: 10.1002/cjoc.201500369
The irregular ZSM-5 zeolites were formed and coated on monolithic interconnected macroporous Al2O3 after seeding progress and impregnated, aged and hydrothermal reaction in the crystallization solution using n-butylamine as template.
Rui Liu, Ran Huo, Yue Bi, Zhixiang Zhao and Qingxiang Liu
Article first published online: 22 JUL 2015 | DOI: 10.1002/cjoc.201500375
One new compound 2 containing two boat-like seven-membered rings was prepared through intramolecular CC coupling reaction under the catalysis of Pd(OAc)2.
Guangyu Wu, Huajuan Zhang, Zufeng Zhan, Qing Lu, Jiejun Cheng, Jianrong Xu and Jun Zhu
Article first published online: 22 JUL 2015 | DOI: 10.1002/cjoc.201500135
A novel MRI contrast agent, hyaluronic acid gadolinium complex (HA-Gd-DTPA) nanospheres, was prepared by the synthesis of hyaluronic acid gadolinium complexes and their assembly, which showed obviously higher relaxation effectiveness and MRI contrast between blood vessel and lymph vessel in rabbit than that of Magnevist.
Yuxiao Liu, Na Yang, Changhu Chu and Renhua Liu
Article first published online: 29 JUN 2015 | DOI: 10.1002/cjoc.201500325
An acceptor-free catalysis protocol for the deoximation of ketoximes and aldoximes using RuCl3 as the catalyst has been developed. Under the optimized conditions, various oximes were converted to ketones and nitriles with excellent isolated yields.
Donghai Liu, Chen Zhang, Xiaohui Lv, Xiaoyu Zheng, Lei Zhang, Linjie Zhi and Quan-Hong Yang
Article first published online: 29 JUN 2015 | DOI: 10.1002/cjoc.201500321
A three-dimensional graphene/S hybrid (G/S) is prepared. Freeze drying and evaporation-induced drying can induce different density and porous structure of G/S. The resulting hybrid can deliver a high specific capacity and good cyclicality.
Qian Li, Junfeng Xiang and Yalin Tang
Article first published online: 29 JUN 2015 | DOI: 10.1002/cjoc.201400841
Novel non-flat G-quadruplex ligands exhibit good stabilization to G-quadruplex structure. The ligand and the G-quadruplex form a 2:1 complex.
Ge Wang, Wenhui Wu, Quangang Zhu, Shiqing Fu, Xiaoyu Wang, Shaotong Hong, Ruihua Guo and Bin Bao
Article first published online: 10 JUN 2015 | DOI: 10.1002/cjoc.201500176
An isoindolone derivative, Fungi fibrinolytic compound (FGFC1), was isolated from a rare marine microorganism strain Stachybotrys longispora FG216 and also evaluated for fibrinolytic activity in vitro and in vivo. FGFC1 is a potential thrombolytic activity agent in the future.
Xin Fan, Zhewei Yang and Zheng Liu
Article first published online: 5 MAY 2015 | DOI: 10.1002/cjoc.201500076
Graphene/polyaniline nanotube (GPNT) composite was synthesized using Vitamin C as both the template of polyaniline nanotube via in situ polymerization of aniline and the reducing agent of graphene oxide.