Advanced Synthesis & Catalysis
Copyright © 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor: Joe P. Richmond, Chairman of the Editorial Board: Ryoji Noyori
Impact Factor: 5.535
ISI Journal Citation Reports © Ranking: 2012: 2/71 (Chemistry Applied); 7/57 (Chemistry Organic)
Online ISSN: 1615-4169
Associated Title(s): Angewandte Chemie International Edition, Asian Journal of Organic Chemistry, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemCatChem, European Journal of Organic Chemistry
Cover Picture: (Adv. Synth. Catal. 1/2014)
The cover picture, provided by the group of A. Stephen K. Hashmi, shows some aspects of the state of the art of gold catalysis. Gold is not only the metal presented to the winners of the most prestigious contests of the year, such as the 2014 soccer World Cup in Brazil, it can also be converted into catalysts that activate multiple bonds for various transformations. Examples of such reactions, which were developed in the Hashmi group and result in a rapid increase of molecular complexity, are shown, along with catalysts enabling these reactions. The chemist and artist who designed this picture is Svetlana Tšupova.
Inside Front Cover: Asymmetric Aldol Reaction of 3-Acetyl-2H-chromen-2-ones and Isatins Catalyzed by a Bifunctional Quinidine Urea Catalyst (Adv. Synth. Catal. 1/2014)
The inside cover picture, provided by Santhi Abbaraju and John Cong-Gui Zhao, illustrates the catalytic action of a quinidine-derived urea catalyst in the title reaction. The bifunctional catalyst enolizes 3-acetyl-2H-chromen-2-one using its Brnsted base moiety and simultaneously activates isatin through hydrogen bonding using its urea moiety. Such synergistic actions yield the corresponding aldol product, which is difficult to obtain via other methods due to its labile nature, in high yield and enantioselectivity, as is reported in the update by Santhi Abbaraju and John Cong-Gui Zhao on pages 237–241 (DOI: "10.1002/adsc.201300623).