Journal of Separation Science

Cover image for Vol. 39 Issue 13

Impact Factor: 2.737

ISI Journal Citation Reports © Ranking: 2014: 21/74 (Chemistry Analytical)

Online ISSN: 1615-9314

Associated Title(s): ELECTROPHORESIS

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Special Issue

Focus on Protein and Macromolecular Separations

Focus on Protein and Macromolecular SeparationsDear Colleagues,
The separation of synthetic and natural macromolecules requires special considerations relative to small molecule separations. Proteins are integral components in life processes. They are targets for discovery and analysis for the determination of new disease biomarkers and they are central to the increasing development of the biopharmaceutical industry. Their complexity in terms of abundance, form, and function makes them challenging, but essential targets for analytical separation and detection. Their vast range in sizes and chemical make-up provide an endless variety of properties that can be manipulated to create materials with functions too numerous to list. Whether formed in nature or by man, macromolecules are essential to human existence, and as analytical chemists, we must constantly evolve new means to handle, speciate, and determine their identity, composition, and abundance. It is for these reasons that we organized a special focus on protein and macromolecular separations for this issue of the Journal of Separation Science

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NEW Virtual Issue

Molecular Imprinting in Separation Science (Editor: Tyge Greibrokk)

Molecular imprinting is a method of inducing molecular recognition properties into synthetic polymers in the presence of a template during the formation of the polymer. Functional monomers are polymerized and cross-linked around the template, leading to a three-dimensional network polymer. Removal of the template from the polymer liberates binding sites complimentary in shape and binding groups to the template. Molecularly imprinted polymers (MIPs) are expected to exhibit high selectivity and high affinity towards a single compound or a class of compounds. In separation science, MIPs are used for the extraction and preconcentration of analytes or for the removal of unwanted contaminants. In addition, MIPs can also be used in assays, as sensors and as drug-release materials. Manuscripts published on this topic between March and December 2015 are included in this Virtual Issue. These papers cover a variety of topics, all related to the preparation of and/or applications of MIPs in separation science.

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