Advanced Functional Materials
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Tissue Repair: Wet-Spun Biodegradable Fibers on Conducting Platforms: Novel Architectures for Muscle Regeneration (Adv. Funct. Mater. 21/2009)
Bio-synthetic platforms, consisting of a conducting polymer substrate overlaid with aligned biodegradable fibers promote the linear growth (ex vivo) of partially differentiated muscle fibers, consistent with the structural requirements of skeletal muscle in vivo, as described by J. M. Razal et al. on page 3381. The conducting surface facilitates development of electrical stimulation paradigms for optimizing muscle growth and development ex vivo that may potentially be applied to repair diseased or damaged muscle.