Advanced Functional Materials
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Biomimetic Structures: Biomimetic Structures: Biological Implications of Dipeptide-Substituted Polyphosphazene–Polyester Blend Nanofiber Matrices for Load-Bearing Bone Regeneration (Adv. Funct. Mater. 14/2011)
Successful bone regeneration benefits from 3D bioresorbable scaffolds that mimic the hierarchical architecture and mechanical characteristics of the native tissue extracellular matrix. On page 2641, Cato T. Laurencin and co-workers present a new biomimetic scaffold design composed of electrospun polymeric nanofibers that combines unique material chemistry, hierarchical architecture, and mechanics suitable for load-bearing bone regeneration. This study, for the first time, demonstrates the feasibility of developing a mechanically competent nanofiber matrix via a biomimetic strategy.