Advanced Functional Materials
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor-in-Chief: Joern Ritterbusch, Deputy Editors: Mary De Vita, Yan Li
Online ISSN: 1616-3028
Associated Title(s): Advanced Electronic Materials, Advanced Energy Materials, Advanced Engineering Materials, Advanced Healthcare Materials, Advanced Materials, Advanced Materials Interfaces, Advanced Materials Technologies, Advanced Optical Materials, Advanced Science, Particle & Particle Systems Characterization, Small
Drug Delivery: Iron Oxide Nanotubes for Magnetically Guided Delivery and pH-Activated Release of Insoluble Anticancer Drugs (Adv. Funct. Mater. 18/2011)
Low solubility in water is an intrinsic property of many drugs, which hinders their clinical use. On page 3446, Guang-Hui Ma and co-workers present PEGylated iron oxide nanotubes. The rod-like shape facilitates cellular uptake, and the tube structure possesses a high drug-loading capacity. These nanotubes also exhibit a stealth effect to macrophages, great magnetic response, and low pH-activated release profiles, exhibiting promising potential for delivering insoluble anticancer drugs in clinical applications.