Advanced Functional Materials

Cover image for Vol. 27 Issue 24

22_19i/2012Imaging: Chemiluminescent and Antioxidant Micelles as Theranostic Agents for Hydrogen Peroxide Associated-Inflammatory Diseases (Adv. Funct. Mater. 19/2012)

Chemiluminescent micelles contain polyoxalate and fluorophore in the core and are capable of performing a peroxalate chemiluminescence reaction with hydrogen peroxide. Hydrogen peroxide is generated in large amounts during inflammatory responses. As reported by Dongwon Lee and co-workers on page 4038, diffusion of hydrogen peroxide into the interior of chemiluminescent micelles initiates the peroxalate chemiluminescence reaction and subsequent light emission, allowing the detection of inflammatory diseases.

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