Advanced Functional Materials

Cover image for Vol. 26 Issue 28

23_20i/2013Dynamic Force Spectroscopy: In Situ Atomic Force Microscopy as a Tool for Investigating Interactions and Assembly Dynamics in Biomolecular and Biomineral Systems (Adv. Funct. Mater. 20/2013)

The photograph on the inside cover illustrates the mechanical measurement of bond energies. This is the essence of dynamic force spectroscopy, which uses the bending of an atomic force microscope cantilever to measure the work required to break a bond. On page 2525, James J. De Yoreo and co-workers show how this technique can be used to probe the binding free energy between biominerals and the proteins that control their growth.

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