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Macromolecular Bioscience
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Online ISSN: 1616-5195
Associated Title(s): Advanced Healthcare Materials, Macromolecular Chemistry and Physics, Macromolecular Materials and Engineering, Macromolecular Rapid Communications
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Current Issue:February 2012
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Recently Published Articles
- Two-Component In situ Forming Supramolecular Hydrogels as Advanced Biomaterials in Vitreous Body Surgery
Indra Böhm, Falko Strotmann, Carsten Koopmans, Isabel Wolf, Hans-Joachim Galla and Helmut Ritter
Article first published online: 9 FEB 2012 | DOI: 10.1002/mabi.201100357
Host–guest hydrogels of polymeric CD and an adamantyl-modified polymer provide a new functional biomaterial. Detailed analytical results prove that the biocompatibility reaching control levels and completely overrides the cytotoxic effects. The advantage of this system to form a hydrogel in situ possesses applications as artificial vitreous body replacement.
- Viability of Human Mesenchymal Stem Cells Seeded on Crosslinked Entropy-Elastic Gelatin-Based Hydrogels
Benjamin F. Pierce, Erik Pitterman, Nan Ma, Tim Gebauer, Axel T. Neffe, Magdalena Hölscher, Friedrich Jung and Andreas Lendlein
Article first published online: 7 FEB 2012 | DOI: 10.1002/mabi.201100237
Human mesenchymal stem cells (MSC) show a high viability on gelatin-based networks with tailorable properties. Gelatin crosslinked with lysine diisocyanate ethyl ester in water yielded degradable, sterilizable, and non-toxic hydrogels. The hydrogels have potential as implantable carriers for stem cells, which are needed in regenerative therapies.
- A Microfluidic Approach to Encapsulate Living Cells in Uniform Alginate Hydrogel Microparticles
Carlos J. Martinez, Jin Woong Kim, Congwang Ye, Idelise Ortiz, Amy C. Rowat, Manuel Marquez and David Weitz
Article first published online: 7 FEB 2012 | DOI: 10.1002/mabi.201100351
A microfluidic technique is introduced for encapsulation of living cells in alginate hydrogel microparticles. The key to the approach is the use of water/oil/water double emulsions as a template to fabricate uniform alginate hydrogel microparticles. This technique offers both excellent control over drop formation, and gentle cell encapsulation.
