Macromolecular Bioscience

Cover image for Vol. 15 Issue 7

Editor-in-Chief: Kirsten Severing, Editor: Anne Pfisterer

Online ISSN: 1616-5195

Associated Title(s): Advanced Healthcare Materials, Macromolecular Chemistry and Physics, Macromolecular Materials and Engineering, Macromolecular Rapid Communications

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Recently Published Articles

  1. Nontoxic, Hydrophilic Cationic Polymers—Identified as Class of Antimicrobial Polymers

    Arne Strassburg, Frauke Kracke, Julia Wenners, Anna Jemeljanova, Jannis Kuepper, Hanne Petersen and Joerg C. Tiller

    Article first published online: 4 AUG 2015 | DOI: 10.1002/mabi.201500207

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    Antimicrobially active and nontoxic hydrophilic polycations based on 1,4-dibromo-2-butene and tetramethyl-1,3-propanediamine named PBI are an alternative to toxic biocides and amphiphilic polycations. Investigations on PBIs with defined molecular weight (Mn) and tailored end groups revealed that there is a dependence of antimicrobial activity and selectivity on Mn and nature of the end groups.

  2. Star-Shaped, Biodegradable, and Elastomeric PLLA-PEG-POSS Hybrid Membrane With Biomineralization Activity for Guiding Bone Tissue Regeneration

    Meihua Xie, Juan Ge, Bo Lei, Qian Zhang, Xiaofeng Chen and Peter X. Ma

    Article first published online: 4 AUG 2015 | DOI: 10.1002/mabi.201500237

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    Novel degradable star-shaped poly-L-lactide-poly (ethylene glycol)-polyhedral oligomeric silsesquioxane (SPPS) hybrid implants with highly controlled mechanical properties, and with elastomeric behavior, biomineralization activity, and cell biocompatibility are fabricated successfully by a facile photo-crosslinking method.

  3. Biofunctional Materials Based on Amino Cellulose Derivatives – A Nanobiotechnological Concept

    Thomas Heinze, Melanie Siebert, Peter Berlin and Andreas Koschella

    Article first published online: 30 JUL 2015 | DOI: 10.1002/mabi.201500184

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    Amino cellulose derivatives simply available by nucleophilic displacement reactions of tosyl cellulose with a broad variety of amines possess an extraordinary ability for self-assembling. Nanocomposites and monolayers may be formed on various substrates. For example, the modified surfaces are efficient carriers for (bio) functional molecules yielding efficient biosensors.

  4. Anti-Resorptive Functions of Poly(ethylene sodium phosphate) on Human Osteoclasts

    Sujit Kootala, Masahiro Tokunaga, Jöns Hilborn and Yasuhiko Iwasaki

    Article first published online: 29 JUL 2015 | DOI: 10.1002/mabi.201500166

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    The effect of poly(ethylene sodium phosphate) (PEP · Na) on human osteoclasts is studied. PEP · Na exhibits excellent biocompatibility with osteoblasts, whereas the polymer effectively reduces the adhesion of osteoclasts adhered on bone slices. This is the first report to describe the possibility of using polyphosphoesters for selective inhibition of osteoclast adhesion and function.

  5. Anti-Bioadhesive Coating Based on Easy to Make Pseudozwitterionic RAFT Block Copolymers for Blood-Contacting Applications

    Sabrina Nehache, Chin-Cheng Yeh, Mona Semsarilar, André Deratani, Yung Chang and Damien Quemener

    Article first published online: 29 JUL 2015 | DOI: 10.1002/mabi.201500185

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    Well-defined pseudozwitterionic diblock copolymers are synthesized using RAFT chemistry. These charged polymers are then used to prepare anti-bioadhesion surfaces that could be used in blood-contact devices. It is demonstrated that such coatings prevent blood protein adsorption to the polymer modified surfaces.

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