Tailor-Made Nanocontainers for Combined Magnetic-Field-Induced Release and MRI
Markus B. Bannwarth, Sandro Ebert, Maximilian Lauck, Ulrich Ziener, Stephanie Tomcin, Gerhard Jakob, Kerstin Münnemann, Volker Mailänder, Anna Musyanovych and Katharina Landfester
Article first published online: 9 MAY 2014 | DOI: 10.1002/mabi.201400122
All-in-one nanocontainers: Tailor-made nanocapsules with integrated superparamagnetic nanoparticles and equipped with a thermo-labile shell possess dual-functionality. After efficient encapsulation of a model dye, a release of the payload can be externally triggered by application of an alternating magnetic field. Additionally, the nanocontainers with encapsulated magnetic nanoparticles can act as contrast agents for magnetic resonance imaging.