Generation of Large-Scale DNA Hydrogels with Excellent Blood and Cell Compatibility
Heidi Stoll, Heidrun Steinle, Katharina Stang, Silju Kunnakattu, Lutz Scheideler, Bernd Neumann, Julia Kurz, Ilka Degenkolbe, Nadja Perle, Christian Schlensak, Hans Peter Wendel and Meltem Avci-Adali
Version of Record online: 19 OCT 2016 | DOI: 10.1002/mabi.201600252
A DNA hydrogel is enzymatically produced via rolling circle amplification (RCA) and multiprimed chain amplification (MCA) in cm scale as a potential material for tissue engineering. The extensive analyses of this DNA hydrogel demonstrate the excellent cyto- and hemocompatibility, which encourages its prospective application as a scaffold for regenerative medicine.