Enzymatic Mineralization of Silk Scaffolds
Sangram K. Samal, Mamoni Dash, Heidi A. Declercq, Tom Gheysens, Jolien Dendooven, Pascal Van Der Voort, Ria Cornelissen, Peter Dubruel and David L. Kaplan
Article first published online: 7 MAR 2014 | DOI: 10.1002/mabi.201300513
Alkaline phosphatase-mediated formation of apatitic minerals on porous silk protein (SFP) scaffolds. The mineral structures differ as a function of ALP concentration. The mineralized SFP scaffolds are effective in improving cellular adhesion, proliferation, and colonization by osteogenic cells.