Cover image for Vol. 12 Issue 6

Editorial Board Chairs: Antonello Mai, Rainer Metternich. Assoc. Editors: David Peralta, Scott Williams (Sr)

Impact Factor: 2.98

ISI Journal Citation Reports © Ranking: 2015: 18/59 (Chemistry Medicinal); 77/255 (Pharmacology & Pharmacy)

Online ISSN: 1860-7187

Associated Title(s): Angewandte Chemie International Edition, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemBioChem, Medicinal Research Reviews, Molecular Informatics

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March 22, 2017

VIP: The Emerging Picture of Sulfoximines in Drug Discovery

VIP: The Emerging Picture of Sulfoximines in Drug DiscoveryJuan Alberto Sirvent, Dr. Ulrich Lücking*

After being neglected for a long time, sulfoximines, the mono-aza analogues of sulfones, have recently gained considerable recognition as a new and versatile structural motif in the life sciences. The synthetic methodology for sulfoximines has progressed significantly over the last decade; however, the general understanding of this functional group regarding its medicinal-chemistry-relevant properties is still limited. Read more...

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    Thumbnail image of graphical abstract

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