ChemMedChem

Most Cited

Articles on this list are the most frequently cited ones among those published in 2010 or 2011. They have contributed the most to the journal's impact factor in 2012.

• Stefan Peukert, Karen Miller-Moslin
  Small-Molecule Inhibitors of the Hedgehog Signaling Pathway as Cancer Therapeutics [Review]
  ChemMedChem 2010, vol. 5, pp. 500–512
• Elena Vergara, Angela Casini, Francesca Sorrentino, Olivier Zava, Elena Cerrada, Maria Pia Rigobello, Alberto Bindoli, Mariano Laguna, Paul J. Dyson
  Anticancer Therapeutics That Target Selenoenzymes: Synthesis, Characterization, in vitro Cytotoxicity, and Thioredoxin Reductase Inhibition of a Series of Gold(I) Complexes Containing Hydrophilic Phosphine Ligands [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 96–102
• Siddharth Shukla, Chintan S. Sumaria, P. I. Pradeepkumar
  Exploring Chemical Modifications for siRNA Therapeutics: A Structural and Functional Outlook [Review]
  ChemMedChem 2010, vol. 5, pp. 328–349
• Daniel D. Robinson, Woody Sherman, Ramy Farid
  Understanding Kinase Selectivity Through Energetic Analysis of Binding Site Waters [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 618–627
• Lifeng Cai, Shibo Jiang
  Development of Peptide and Small-Molecule HIV-1 Fusion Inhibitors that Target gp41 [Minireview]
  ChemMedChem 2010, vol. 5, pp. 1813–1824
• Richard K. Haynes, Wing-Chi Chan, Ho-Ning Wong, Ka-Yan Li, Wai-Keung Wu, Kit-Man Fan, Herman H. Y. Sung, Ian D. Williams, Davide Prosperi, Sergio Melato, Paolo Coghi, Diego Monti
  Facile Oxidation of Leucomethylene Blue and Dihydroflavins by Artemisinins: Relationship with Flavoenzyme Function and Antimalarial Mechanism of Action [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 1282–1299
• Dennis M. Krüger, Andreas Evers
  Comparison of Structure- and Ligand-Based Virtual Screening Protocols Considering Hit List Complementarity and Enrichment Factors [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 148–158
• Sabine Amslinger
  The Tunable Functionality of α,β-Unsaturated Carbonyl Compounds Enables Their Differential Application in Biological Systems [Concept]
  ChemMedChem 2010, vol. 5, pp. 351–356
• Laith Q. Al-Mawsawi, Nouri Neamati
  Allosteric Inhibitor Development Targeting HIV-1 Integrase [Review]
  ChemMedChem 2011, vol. 6, pp. 228–241
• Tihomir Tomašić, Nace Zidar, Andreja Kovač, Samo Turk, Mihael Simčič, Didier Blanot, Manica Müller-Premru, Metka Filipič, Simona Golič Grdadolnik, Anamarija Zega, Marko Anderluh, Stanislav Gobec, Danijel Kikelj, Lucija Peterlin Mašič
  5-Benzylidenethiazolidin-4-ones as Multitarget Inhibitors of Bacterial Mur Ligases [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 286–295
• Robert Abel, Noeris K. Salam, John Shelley, Ramy Farid, Richard A. Friesner, Woody Sherman
  Contribution of Explicit Solvent Effects to the Binding Affinity of Small-Molecule Inhibitors in Blood Coagulation Factor Serine Proteases [Full Paper]
  ChemMedChem 2011, vol. 6, pp. 1049–1066
• Farah Oulaïdi, Sophie Front-Deschamps, Estelle Gallienne, Eric Lesellier, Kyoko Ikeda, Naoki Asano, Philippe Compain, Olivier R. Martin
  Second-Generation Iminoxylitol-Based Pharmacological Chaperones for the Treatment of Gaucher Disease [Full Paper]
  ChemMedChem 2011, vol. 6, pp. 353–361
• João P. Ribeiro, Sabine André, F. Javier Cañada, Hans-Joachim Gabius, Anna Paola Butera, Ricardo José Alves, Jesús Jiménez-Barbero
  Lectin-Based Drug Design: Combined Strategy to Identify Lead Compounds using STD NMR Spectroscopy, Solid-Phase Assays and Cell Binding for a Plant Toxin Model [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 415–419
• Darja Lavogina, Erki Enkvist, Asko Uri
  Bisubstrate Inhibitors of Protein Kinases: from Principle to Practical Applications [Minireview]
  ChemMedChem 2010, vol. 5, pp. 23–34
• Hans-Jörg Breyholz, Stefan Wagner, Andreas Faust, Burkhard Riemann, Carsten Höltke, Sven Hermann, Otmar Schober, Michael Schäfers, Klaus Kopka
  Radiofluorinated Pyrimidine-2,4,6-triones as Molecular Probes for Noninvasive MMP-Targeted Imaging [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 777–789
• Xuelai Liu, Pui-yan Lee, Chi-ming Ho, Vincent C. H. Lui, Yan Chen, Chi-ming Che, Paul K. H. Tam, Kenneth K. Y. Wong
  Silver Nanoparticles Mediate Differential Responses in Keratinocytes and Fibroblasts during Skin Wound Healing [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 468–475
• Kok Ping Chan, David Y.-K. Chen
  Chemical Synthesis and Biological Evaluation of the Englerin Analogues [Communication]
  ChemMedChem 2011, vol. 6, pp. 420–423
• Teresa Gonzalo, Maria Isabel Clemente, Louis Chonco, Nick D. Weber, Laura Díaz, María Jesús Serramía, Rafael Gras, Paula Ortega, F. Javier de la Mata, Rafael Gómez, Luis A. Lopez-Fernández, Maria Angeles Muñoz-Fernández, José Luís Jiménez
  Gene Therapy in HIV-Infected Cells to Decrease Viral Impact by Using an Alternative Delivery Method [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 921–929
• Munikumar R. Doddareddy, Elisabeth C. Klaasse, Shagufta, Adriaan P. IJzerman, Andreas Bender
  Prospective Validation of a Comprehensive In silico hERG Model and its Applications to Commercial Compound and Drug Databases [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 716–729
• Sabrina Castellano, Ciro Milite, Rino Ragno, Silvia Simeoni, Antonello Mai, Vittorio Limongelli, Ettore Novellino, Ingo Bauer, Gerald Brosch, Astrid Spannhoff, Donghang Cheng, Mark T. Bedford, Gianluca Sbardella
  Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI-1) [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 398–414
• Janusz M. Dąbrowski, Krystyna Urbanska, Luis G. Arnaut, Mariette M. Pereira, Artur R. Abreu, Sérgio Simões, Grażyna Stochel
  Biodistribution and Photodynamic Efficacy of a Water-Soluble, Stable, Halogenated Bacteriochlorin against Melanoma [Full Paper]
  ChemMedChem 2011, vol. 6, pp. 465–475
• Samir Messaoudi, Abdallah Hamze, Olivier Provot, Bret Tréguier, Jordi Rodrigo De Losada, Jérôme Bignon, Jian-Miao Liu, Joanna Wdzieczak-Bakala, Sylviane Thoret, Joëlle Dubois, Jean-Daniel Brion, Mouad Alami
  Discovery of Isoerianin Analogues as Promising Anticancer Agents [Full Paper]
  ChemMedChem 2011, vol. 6, pp. 488–497
• Claudio Dalvit, Anna Vulpetti
  Fluorine–Protein Interactions and ¹⁹F NMR Isotropic Chemical Shifts: An Empirical Correlation with Implications for Drug Design [Full Paper]
  ChemMedChem 2011, vol. 6, pp. 104–114
• Anne Mai Wassermann, Lisa Peltason, Jürgen Bajorath
  Computational Analysis of Multi-target Structure–Activity Relationships to Derive Preference Orders for Chemical Modifications toward Target Selectivity [Full Paper]
  ChemMedChem 2010, vol. 5, pp. 847–858
• Edmund J. Keliher, Thomas Reiner, Anna Turetsky, Scott A. Hilderbrand, Ralph Weissleder
  High-Yielding, Two-Step ¹⁸F Labeling Strategy for ¹⁸F-PARP1 Inhibitors [Communication]
  ChemMedChem 2011, vol. 6, pp. 424–427

Last update: 22-4-2013