Cover image for Vol. 12 Issue 10

Editorial Board Chairs: Antonello Mai, Rainer Metternich. Assoc. Editors: David Peralta, Scott Williams (Sr)

Impact Factor: 2.98

ISI Journal Citation Reports © Ranking: 2015: 18/59 (Chemistry Medicinal); 77/255 (Pharmacology & Pharmacy)

Online ISSN: 1860-7187

Associated Title(s): Angewandte Chemie International Edition, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemBioChem, Medicinal Research Reviews, Molecular Informatics

August 28, 2008

Ley, Seeberger, and Kubinyi Awarded

Ley, Seeberger, and Kubinyi Awarded

The European Federation for Medicinal Chemistry (EFMC) presented awards to outstanding scientists at the Twentieth International Symposium in Vienna.

The Prous Institute Overton and Meyer Award for new technologies in drug design went to Steven V. Ley (University of Cambridge, UK). The EFMC honored him for his achievements in methodology development and the total synthesis of natural products. Particularly sensational was Ley's total synthesis of azadirachtin, twenty years after this natural product was isolated.[1], His group recently reported in Chemistry—A European Journal on the organocatalytic enantioselective addition of malonates to α,β-unsaturated enones.[1] Ley is a member of the editorial boards of Chemistry—A European Journal, ChemBioChem, ChemMedChem, and Advanced Synthesis & Catalysis.

The EFMC presents this year's UCB–Ehrlich Award for Excellence in Medicinal Chemistry to Peter H. Seeberger. He has been professor of organic chemistry since 2003 at the ETH in Zurich, and researches at the interface between biology and chemistry. He is particularly interested in oligosaccharides that control the interactions between cells. Using an automated oligosaccharide synthesizer that he developed, Seeberger was able to artificially produce known glycanes of pathogens and to further develop them into potential vaccines against illnesses, such as Leishmaniosis, malaria, AIDS, anthrax, and tuberculosis. Seeberger is a member of the editorial advisory board of QSAR & Combinatorial Science. There he recently discussed the development of carbohydrate microarrays[2]; in Chemistry—A European Journal he reported on the automated solid-phase synthesis of protected oligosaccharides with β-mannosidic linkages,[2] and in Chemistry—An Asian Journal he presented the total synthesis of sialylated glycanes that are related to influenza in humans and birds.[2]

With the Nauta Award for Pharmacochemistry, the EFMC honors outstanding achievement in the development and international organization of medicinal chemistry. This year the prize goes to Hugo Kubinyi (formerly at BASF AG, Ludwigshafen). Kubinyi has contributed substantially to chemical informatics, quantitative structure–activity relationships (QSAR),[3], and to combinatorial chemistry and drug development. He heads the editorial advisory board of the journal QSAR & Combinatorial Science and is co-editor of the book series Methods and Principles in Medicinal Chemistry (Wiley-VCH) and co-author of two books in the series.

[1] a) G. E. Veitch, E. Beckmann, B. J. Burke, A. Boyer, S. L. Maslen, S. V. Ley, Angew. Chem. 2007, 119, 7773; Angew. Chem. Int. Ed. 2007, 46, 7629; b) G. E. Veitch, E. Beckmann, B. J. Burke, A. Boyer, C. Ayats, S. V. Ley, Angew. Chem. 2007, 119, 7777; Angew. Chem. Int. Ed. 2007, 46, 7633; c) V. Wascholowski, K. Rahbek Knudsen, C. E. T. Mitchell, S. V. Ley, Chem. Eur. J. 2008, 14, 6155.

[2] a) J. L. de Paz, P. H. Seeberger, QSAR Comb. Sci. 2006, 25, 1027; b) J. D. C. Codée, L. Kröck, B. Castagner, P. H. Seeberger, Chem. Eur. J. 2008, 14, 3987; c) S. Hanashima, P. H. Seeberger, Chem. Asian J. 2007, 2, 1447.

[3] a) H. Kubinyi, Chem. Unserer Zeit 1986, 20, 191; b) H. Kubinyi, Quant. Struct.-Act. Rel. 2002, 21, 348.

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