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August 31, 2009
ChemMedChem 09/2009: Shockingly Hot!
In this issue's Minireview, Sgobba and Rastelli discuss the role of structure-based and in silico techniques in the design and development of heat shock protein 90 (Hsp89) inhibitors and their potential as therapeutic agents.
A cluster of five contributions, describing original research on neurological agents, highlights the importance of diseases such as Alzheimer's and conditions such as anxiety, and the need for novel therapeutics in this field. Giralt et al. describe novel peptide-derived β-amyloid aggregation inhibitors, while Albericio and Royo illustrate the utility of indoloquinolizidine–peptide hybrids as dopamine receptor agonists.
This new clustering feature of ChemMedChem is aimed at highlighting areas of research and ensuring easy navigation of interested readers to important pages. You will find the cluster key words on the front cover of each issue, and a short description of the cluster in the Table of Contents.