Cover image for Vol. 11 Issue 20

Editorial Board Chairs: Antonello Mai, Rainer Metternich. Assoc. Editors: David Peralta, Scott Williams (Sr)

Impact Factor: 2.98

ISI Journal Citation Reports © Ranking: 2015: 18/59 (Chemistry Medicinal); 76/253 (Pharmacology & Pharmacy)

Online ISSN: 1860-7187

Associated Title(s): Angewandte Chemie International Edition, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemBioChem, Medicinal Research Reviews, Molecular Informatics

March 29, 2011

ChemMedChem 04/2011: Women in Chemistry (IYC 2011)

ChemMedChem 04/2011: Women in Chemistry (IYC 2011)The April issue of ChemMedChem is dedicated to women in chemistry, medicinal chemistry in particular.

Two of ChemMedChem's Board members, Professor Gloria Cristalli and Professor Maria Laura Bolognesi, introduce this issue with their Editorial Remembering Marie Curie's Legacy, which highlights a few of the many examples in which female chemists have contributed enormously to their field. Another ChemMedChem Board member, Professor Concepción González-Bello, is featured this month in our Author Profile section.

In their Minireview, Mariangela Biava et al. discuss lead optimization strategies that have led to the discovery of pyrrole derivatives with anti-mycobacterial activity.

This issue contains six Communications: M. L. Bolognesi and colleagues present their work on bifunctional anti-prion compounds that combine a prion-recognition motif with an antioxidant motif. Luciana Mosca et al. introduce a compound that protects cells against oxidative stress while also acting as a PARP-1 inhibitor. Anne K. Duhme-Klair and colleagues present their work on molybdenum-based xanthine oxidase inhibitors. Mikiko Sodeoka and co-workers discuss their development of a phosphatase inhibitor that contains a non-acidic phosphate-mimicking core. Tatiana Segura and colleagues describe clustered Arg-Gly-Asp peptides that enhance the tumor targeting of nonviral vectors for PET imaging. Finally, Fernanda Borges and co-workers present a new class of monoamine oxidase inhibitors.

Stefanie Keil et al. kick off the Full Papers with a presentation of their work on potent partial dual PPAR δ/γ agonists. Aiming Sun, John A. Katzenellenbogen, et&nbspal. discuss their screening and development of compounds that interfere with estrogen receptor–coactivator binding. Emmanuelle Briard et al. present their work on an iodinated radiotracer for PET and SPECT imaging of myelin. Luisa Bracci, Giancarlo Morelli and colleagues discuss target-selective drug delivery using liposomes labeled with neurotensin peptides. Sonsoles Velázquez and co-workers present their synthesis of some unusual bicyclic and heterocyclic compounds with cytostatic and antiviral activity. Lucia Altucci, Antonello Mai, and colleagues reveal the apoptosis-inducing and cytodifferentiation activity of cinnamyl-containing HDAC inhibitors. Mei Lin Go and co-workers present their research on aurones as modulators of ATP binding cassette (ABC) transport proteins. Finally, Charlotte G. Jørgensen et al. present their discovery of benzamide analogues as a new class of 5-HT3 receptor agonists.

We hope you enjoy this special issue of ChemMedChem celebrating women in chemistry. Browse it today!

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