January 19, 2016
2016 Wolf Prize Goes to Nicolaou and Schreiber
Congratulations to professors K. C. Nicolaou (Rice University, Department of Chemistry) and Stuart L. Schreiber (Harvard University, Department of Chemistry & Chemical Biology), who are this year's recipients of the Wolf Prize in Chemistry.
Nicolaou is being recognized for his research group's work in advancing the field of chemical synthesis to the extremes of molecular complexity, linking structure and function and exploring the interfaces between chemistry, biology, and medicine.
Schreiber's award acknowledges his group's pioneering chemical insights into the logic of signal transduction and gene regulation that have led to new therapeutics, as well as advances in chemical biology and medicine through the discovery of small-molecule probes.
The Israel Chemical Society will organize a one-day symposium in honor of both Wolf Prize laureates on June 1, 2016; the symposium will be hosted by the Schulich Faculty of Chemistry of the Technion — Israel Institute of Technology. The Prize ceremony will take place in the Knesset on the following day, June 2.
Nicolaou's Communication, Molecular Design and Chemical Synthesis of a Highly Potent Epothilone, appeared in ChemMedChem's inaugural issue, reporting the science behind the artwork on the journal's first issue cover. This was followed the next year with a Review by Nicolaou, Altmann, and colleagues on the chemistry and biology of epothilones.
More recent publications from the Nicolaou group include a 2015 report on epothilone B side chain analogues, and a January 2016 Communication about imatinib analogues with unusual structural motifs.