Biotechnology Journal

Cover image for Vol. 11 Issue 10

Edited By: Alois Jungbauer and Sang Yup Lee

Impact Factor: 3.781

ISI Journal Citation Reports © Ranking: 2015: 17/77 (BIOCHEMICAL RESEARCH METHODS); 34/161 (Biotechnology & Applied Microbiology)

Online ISSN: 1860-7314

Biotechnology in Biomedicine Virtual Issue

Biotechnology and Bioengineering
Vaccine process technology 

Debottlenecking recombinant protein production in Bacillus megaterium under large-scale conditions—targeted precursor feeding designed from metabolomics

Biotechnology Journal
Current progress of siRNA/shRNA therapeutics in clinical trials 

Metabolic engineering for the production of clinically important molecules: Omega-3 fatty acids, artemisinin, and taxol

Biotechnology Progress
Synthesis and characterization of bovine serum albumin-coated nanocapsules loaded with indocyanine green as potential multifunctional nanoconstructs

Encapsulation of hemoglobin inside liposomes surface conjugated with poly(ethylene glycol) attenuates their reactions with gaseous ligands and regulates nitric oxide dependent vasodilation


Somatic cell reprogramming for regenerative medicine: SCNT vs. iPS cells

Immune tolerance: Are regulatory T cell subsets needed to explain suppression of autoimmunity?

Extracellular vesicles – vehicles that spread cancer genes

Towards Alzheimer's root cause: ECSIT as an integrating hub between oxidative stress, inflammation and mitochondrial dysfunction : Hypothetical role of the adapter protein ECSIT in familial and sporadic Alzheimer's disease pathogenesis

Balancing self-renewal and differentiation by asymmetric division: Insights from brain tumor suppressors in Drosophila neural stem cells

CREB signalling in neural stem/progenitor cells: Recent developments and the implications for brain tumour biology

 Journal of Chemical Technology and Biotechnology

Current strategies and challenges for the purification of stem cells


WIREs Nanomedicine and Nanotechnology

Cancer nanotechnology research in the United States and China: Cooperation to promote innovation

Development of molecular imaging and nanomedicine in China 

Recent advances in stealth coating of nanoparticle drug delivery systems

Thermally responsive polymer­nanoparticle composites for biomedical applications


mRNA export and cancer


Integrative Bioinformatics: A collection of articles from WIREs Systems Biology and Medicine The 2012 International Symposium on Integrative Bioinformatics (IB2012) was held in April 2012 at Hangzhou, China. For more information, please go to

Drug Discovery: An Interdisciplinary View Drug discovery requires a multitude of steps, from identifying targets, to synthesis, screening, and efficacy testing. Multidisciplinary research is required for the discovery process, as highlighted by the articles selected.

Therapeutics: An Interdisciplinary View A collection of articles published throughout the Wiley Interdisciplinary Reviews (WIREs) series on the treatment of various acute and chronic diseases.

Fluorescence in Nanodiagnostics This collection of articles from WIREs Nanomedicine and Nanobiotechnology features fluorescence as a diagnostic tool. The articles cover its uses as quantum dots and contrast agents, and applications in cancer and respiratory disease.

HIV Vaccine Approaches 


Vaccination of Humans

HPV Vaccine

Repetitive Elements: Bioinformatic Identification, Classification and Analysis

Role of Bioinformatics in Genome-wide Association Studies 

Microarray Bioinformatics

FEMS Microbiology Letters
DevR (DosR) binding peptide inhibits adaptation of Mycobacterium tuberculosis under hypoxia

FEMS Yeast Research
Genome sequence of Wickerhamomyces anomalus DSM 6766 reveals genetic basis of biotechnologically important antimicrobial activities

A systems-level approach for metabolic engineering of yeast cell factories

Journal of Applied Microbiology
Biodegradation of kraft lignin by a bacterial strain Comamonas sp. B-9 isolated from eroded bamboo slips

Journal of Chemical Technology and Biotechnology
Current strategies and challenges for the purification of stem cells

Microbial Biotechnology
Transcriptional profiling of vaccine-induced immune responses in humans and non-human primates 

Relevant uses of surface proteins – display on self-organized biological structures

Statistical optimization of simple culture conditions to produce biomass of an ochratoxigenic mould biocontrol yeast strain

Microbial Biotechnology
Transcriptional profiling of vaccine-induced immune responses in humans and non-human primates

 Relevant uses of surface proteins – display on self-organized biological structures

 Books / Reference Works / Current Protocols

 Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications, 2nd Edition

Table of Contents

 Therapeutic Proteins: Strategies to Modulate Their Plasma Half-lives

Sample Chapter

 Molecular and Cellular Therapeutics

Table of Contents

 Statistical Modelling of Molecular Descriptors in QSAR/QSPR

Table of Contents

 Bioinformatics and Biomarker Discovery: "Omic" Data Analysis for Personalized Medicine

Sample Chapter

 Drug Distribution and Pharmacokinetics: From Principles to Applications

Sample Chapter

 Handbook of Therapeutic Antibodies: Technologies, Emerging Developments and Approved Therapeutics

Table of Contents

 Epigenetic Regulation and Epigenomics

Table of Contents

 Series: Drug Discovery in Infectious Diseases

Titles in this series:

Parasitic Helminths

Antiparasitic and Antibacterial Drug Discovery

Apicomplexan Parasites: Molecular Approaches toward Targeted Drug Development

Advances in Malignant Hematology

Sample Chapter

 Leukaemia Diagnosis 4e

Sample Chapter

 Current Protocols in Immunology

Production of Polyclonal Antisera

Production of Monoclonal Antibodies

 Current Protocols in Toxicology

High-Throughput, Multiplexed Analysis of 3-Nitrotyrosine in Individual Proteins

 Current Protocols in Neuroscience

Assessment of Motor Coordination and Balance in Mice Using the Rotarod, Elevated Bridge, and Footprint Tests

Use of Channelrhodopsin for Activation of CNS Neurons

 Current Protocols in Mouse Biology

Hematology Testing in Mice

 Current Protocols in Nucleic Acid Chemistry

Recent Progress in DNA Origami Technology 

A Status Update of Modified Oligonucleotides for Chemotherapeutics Application

 Current Protocols in Microbiology

Screening of Hepatitis C Virus Inhibitors Using Genotype 1a HCV Replicon Cell Lines

 Current Protocols in Bioinformatics

Using MACS to Identify Peaks from ChIP-Seq Data

 Current Protocols in Human Genetics

Molecular Diagnosis of Hearing Loss