Raman spectroscopic identification of Mycobacterium tuberculosis
Stephan Stöckel, Susann Meisel, Björn Lorenz, Sandra Kloß, Sandra Henk, Stefan Dees, Elvira Richter, Sönke Andres, Matthias Merker, Ines Labugger, Petra Rösch and Jürgen Popp
Version of Record online: 7 OCT 2016 | DOI: 10.1002/jbio.201600174
Tuberculosis has been a scourge of humankind from time immemorial and is still one of the world's most dangerous diseases. Thus, the per se cultivation-independent Raman microspectroscopy emerges as a perfect tool for a rapid on-the-spot mycobacterial diagnostic test. For the first time, it could be shown that a definite identification of mycobacterial species is possible by using Raman microspectroscopy on single bacterial cells in combination with elaborated statistical methods.