© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor-in-Chief: Guido Kemeling; Editorial Board Chairs: Matthias Beller, Gabriele Centi, Licheng Sun
Impact Factor: 7.116
ISI Journal Citation Reports © Ranking: 2015: 20/163 (Chemistry Multidisciplinary)
Online ISSN: 1864-564X
Cover Picture: Practical Synthesis of Photochromic Diarylethenes in Integrated Flow Microreactor Systems (ChemSusChem 2/2012)
The synthesis of photochromic diarylethenes involves generating heteroaryllithium compounds by a halogen–lithium exchange reaction of heteroaryl halides, and subsequent reaction with octafluorocyclopentene. In a conventional batch macroreactor the reaction should be carried out at temperatures of −78 °C or lower, because heteroaryllithium compounds are often unstable and decompose at higher temperatures. The front cover features research by Jun-ichi Yoshida et al. (page 339), who report a practical method for the synthesis of photochromic diarylethenes by using integrated flow microreactor systems. Reactions can be conducted without using cryogenic conditions by virtue of effective temperature and residence-time control. Moreover, the synthesis of unsymmetrical diarylethenes, which is difficult to achieve using conventional batch macro systems, is accomplished.