Seawater-Based Biocatalytic Strategy: Stereoselective Reductions of Ketones with Marine Yeasts
Dr. Immacolata Serra, Benedetta Guidi, Dr. Gaetan Burgaud, Dr. Martina L. Contente, Prof. Patrizia Ferraboschi, Dr. Andrea Pinto, Prof. Concetta Compagno, Prof. Francesco Molinari and Dr. Diego Romano
Version of Record online: 15 SEP 2016 | DOI: 10.1002/cctc.201600947
All at sea: Marine yeasts from deep-sub-seafloor sediments were grown in seawater and used as biocatalysts to perform the stereoselective reduction of different ketones in seawater as well. Strains of Meyerozyma guilliermondii and Rhodotorula mucilaginosa were able to reduce different aromatic ketones with high molar conversions and moderate-to-high enantioselectivity.